Members of the H3K4 trimethylation complex regulate lifespan in a germline-dependent manner in C. elegans (original) (raw)

• Blander, G. & Guarente, L. The Sir2 family of protein deacetylases. Annu. Rev. Biochem. 73, 417–435 (2004)
  Article CAS PubMed Google Scholar
• Dang, W. et al. Histone H4 lysine 16 acetylation regulates cellular lifespan. Nature 459, 802–807 (2009)
  Article CAS ADS PubMed PubMed Central Google Scholar
• Nottke, A., Colaiacovo, M. P. & Shi, Y. Developmental roles of the histone lysine demethylases. Development 136, 879–889 (2009)
  Article CAS PubMed PubMed Central Google Scholar
• Hamilton, B. et al. A systematic RNAi screen for longevity genes in C. elegans. Genes Dev. 19, 1544–1555 (2005)
  Article CAS PubMed PubMed Central Google Scholar
• Li, J. et al. Caenorhabditis elegans HCF-1 functions in longevity maintenance as a DAF-16 regulator. PLoS Biol. 6, e233 (2008)
  Article PubMed PubMed Central Google Scholar
• McColl, G. et al. Pharmacogenetic analysis of lithium-induced delayed aging in Caenorhabditis elegans. J. Biol. Chem. 283, 350–357 (2008)
  Article CAS PubMed Google Scholar
• Chen, S. et al. The conserved NAD(H)-dependent corepressor CTBP-1 regulates Caenorhabditis elegans life span. Proc. Natl Acad. Sci. USA 106, 1496–1501 (2009)
  Article CAS ADS PubMed PubMed Central Google Scholar
• Siebold, A. P. et al. Polycomb repressive complex 2 and trithorax modulate Drosophila longevity and stress resistance. Proc. Natl Acad. Sci. USA 107, 169–174 (2010)
  Article CAS ADS PubMed Google Scholar
• Wysocka, J., Myers, M. P., Laherty, C. D., Eisenman, R. N. & Herr, W. Human Sin3 deacetylase and trithorax-related Set1/Ash2 histone H3–K4 methyltransferase are tethered together selectively by the cell-proliferation factor HCF-1. Genes Dev. 17, 896–911 (2003)
  Article CAS PubMed PubMed Central Google Scholar
• Lee, S. S. et al. A systematic RNAi screen identifies a critical role for mitochondria in C. elegans longevity. Nature Genet. 33, 40–48 (2003)
  Article CAS PubMed Google Scholar
• Hansen, M., Hsu, A. L., Dillin, A. & Kenyon, C. New genes tied to endocrine, metabolic, and dietary regulation of lifespan from a Caenorhabditis elegans genomic RNAi screen. PLoS Genet. 1, e17 (2005)
  Article PubMed Central Google Scholar
• Miller, T. et al. COMPASS: a complex of proteins associated with a trithorax-related SET domain protein. Proc. Natl Acad. Sci. USA 98, 12902–12907 (2001)
  Article CAS ADS PubMed PubMed Central Google Scholar
• Papoulas, O. et al. The Drosophila trithorax group proteins BRM, ASH1 and ASH2 are subunits of distinct protein complexes. Development 125, 3955–3966 (1998)
  CAS PubMed Google Scholar
• Dou, Y. et al. Regulation of MLL1 H3K4 methyltransferase activity by its core components. Nature Struct. Mol. Biol. 13, 713–719 (2006)
  Article CAS Google Scholar
• Wysocka, J. et al. WDR5 associates with histone H3 methylated at K4 and is essential for H3 K4 methylation and vertebrate development. Cell 121, 859–872 (2005)
  Article CAS PubMed Google Scholar
• Simonet, T., Dulermo, R., Schott, S. & Palladino, F. Antagonistic functions of SET-2/SET1 and HPL/HP1 proteins in C. elegans development. Dev. Biol. 312, 367–383 (2007)
  Article CAS PubMed Google Scholar
• Ruthenburg, A. J., Allis, C. D. & Wysocka, J. Methylation of lysine 4 on histone H3: intricacy of writing and reading a single epigenetic mark. Mol. Cell 25, 15–30 (2007)
  Article CAS PubMed Google Scholar
• Schneider, J. et al. Molecular regulation of histone H3 trimethylation by COMPASS and the regulation of gene expression. Mol. Cell 19, 849–856 (2005)
  Article CAS PubMed Google Scholar
• Christensen, J. et al. RBP2 belongs to a family of demethylases, specific for tri-and dimethylated lysine 4 on histone 3. Cell 128, 1063–1076 (2007)
  Article CAS PubMed Google Scholar
• Xu, L. & Strome, S. Depletion of a novel SET-domain protein enhances the sterility of mes-3 and mes-4 mutants of Caenorhabditis elegans. Genetics 159, 1019–1029 (2001)
  CAS PubMed PubMed Central Google Scholar
• Arantes-Oliveira, N., Apfeld, J., Dillin, A. & Kenyon, C. Regulation of life-span by germ-line stem cells in Caenorhabditis elegans. Science 295, 502–505 (2002)
  Article CAS ADS PubMed Google Scholar
• Berman, J. R. & Kenyon, C. Germ-cell loss extends C. elegans life span through regulation of DAF-16 by kri-1 and lipophilic-hormone signaling. Cell 124, 1055–1068 (2006)
  Article CAS PubMed Google Scholar
• Budovskaya, Y. V. et al. An elt-3/elt-5/elt-6 GATA transcription circuit guides aging in C. elegans. Cell 134, 291–303 (2008)
  Article CAS PubMed PubMed Central Google Scholar
• Sijen, T. et al. On the role of RNA amplification in dsRNA-triggered gene silencing. Cell 107, 465–476 (2001)
  Article CAS PubMed Google Scholar
• Kelly, W. G., Xu, S., Montgomery, M. K. & Fire, A. Distinct requirements for somatic and germline expression of a generally expressed Caenorhabditis elegans gene. Genetics 146, 227–238 (1997)
  CAS PubMed PubMed Central Google Scholar
• Mitchell, D. H., Stiles, J. W., Santelli, J. & Sanadi, D. R. Synchronous growth and aging of Caenorhabditis elegans in the presence of fluorodeoxyuridine. J. Gerontol. 34, 28–36 (1979)
  Article CAS PubMed Google Scholar
• Lee, S. S., Kennedy, S., Tolonen, A. C. & Ruvkun, G. DAF-16 target genes that control C. elegans life-span and metabolism. Science 300, 644–647 (2003)
  Article CAS ADS PubMed Google Scholar
• Haag, E. S., Wang, S. & Kimble, J. Rapid coevolution of the nematode sex-determining genes fem-3 and tra-2. Curr. Biol. 12, 2035–2041 (2002)
  Article CAS PubMed Google Scholar
• Gerisch, B., Weitzel, C., Kober-Eisermann, C., Rottiers, V. & Antebi, A. A hormonal signaling pathway influencing C. elegans metabolism, reproductive development, and life span. Dev. Cell 1, 841–851 (2001)
  Article CAS PubMed Google Scholar
• Greer, E. L. et al. An AMPK-FOXO pathway mediates longevity induced by a novel method of dietary restriction in C. elegans. Curr. Biol. 17, 1646–1656 (2007)
  Article CAS PubMed PubMed Central Google Scholar
• Mello, C. C. et al. The PIE-1 protein and germline specification in C. elegans embryos. Nature 382, 710–712 (1996)
  Article CAS ADS PubMed Google Scholar
• Fire, A., Harrison, S. W. & Dixon, D. A modular set of lacZ fusion vectors for studying gene expression in Caenorhabditis elegans. Gene 93, 189–190 (1990)
  Article CAS PubMed Google Scholar
• Cheeseman, I. M. et al. A conserved protein network controls assembly of the outer kinetochore and its ability to sustain tension. Genes Dev. 18, 2255–2268 (2004)
  Article CAS PubMed PubMed Central Google Scholar
• Venteicher, A. S., Meng, Z., Mason, P. J., Veenstra, T. D. & Artandi, S. E. Identification of ATPases pontin and reptin as telomerase components essential for holoenzyme assembly. Cell 132, 945–957 (2008)
  Article CAS PubMed PubMed Central Google Scholar
• Klassen, M. P. & Shen, K. Wnt signaling positions neuromuscular connectivity by inhibiting synapse formation in C. elegans. Cell 130, 704–716 (2007)
  Article CAS PubMed Google Scholar
• Praitis, V., Casey, E., Collar, D. & Austin, J. Creation of low-copy integrated transgenic lines in Caenorhabditis elegans. Genetics 157, 1217–1226 (2001)
  CAS PubMed PubMed Central Google Scholar
• Merritt, C. & Seydoux, G. In WormBook (ed. The C. elegans Research Community). 10.1895/wormbook.1.148.1 〈http://www.wormbook.org/〉 (2010)
• Tusher, V. G., Tibshirani, R. & Chu, G. Significance analysis of microarrays applied to the ionizing radiation response. Proc. Natl Acad. Sci. USA 98, 5116–5121 (2001)
  Article CAS ADS PubMed PubMed Central Google Scholar
• Eisen, M. B., Spellman, P. T., Brown, P. O. & Botstein, D. Cluster analysis and display of genome-wide expression patterns. Proc. Natl Acad. Sci. USA 95, 14863–14868 (1998)
  Article CAS ADS PubMed PubMed Central Google Scholar
• Saldanha, A. J. Java Treeview–extensible visualization of microarray data. Bioinformatics 20, 3246–3248 (2004)
  Article CAS PubMed Google Scholar
• Beissbarth, T. & Speed, T. P. GOstat: find statistically overrepresented Gene Ontologies within a group of genes. Bioinformatics 20, 1464–1465 (2004)
  Article CAS PubMed Google Scholar
• Shi, X. et al. Modulation of p53 function by SET8-mediated methylation at lysine 382. Mol. Cell 27, 636–646 (2007)
  Article CAS PubMed PubMed Central Google Scholar