Specification of motoneurons from human embryonic stem cells (original) (raw)
Jessell, T.M. Neuronal specification in the spinal cord: inductive signals and transcriptional codes. Nat. Rev. Genet.1, 20–29 (2000). ArticleCASPubMed Google Scholar
Briscoe, J. & Ericson, J. Specification of neuronal fates in the ventral neural tube. Curr. Opin. Neurobiol.11, 43–49 (2001). ArticleCASPubMed Google Scholar
Bally-Cuif, L. & Hammerschmidt, M. Induction and patterning of neuronal development, and its connection to cell cycle control. Curr. Opin. Neurobiol.13, 16–25 (2003). ArticleCASPubMed Google Scholar
Vasiliauskas, D. & Stern, C.D. Patterning the embryonic axis: FGF signaling and how vertebrate embryos measure time. Cell106, 133–136 (2001). ArticleCASPubMed Google Scholar
Martin, G.R. Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells. Proc. Natl. Acad. Sci. USA78, 7634–7638 (1981). ArticleCASPubMedPubMed Central Google Scholar
Evans, M.J. & Kaufman, M.H. Establishment in culture of pluripotential cells from mouse embryos. Nature292, 154–156 (1981). ArticleCASPubMed Google Scholar
Tropepe, V. et al. Direct neural fate specification from embryonic stem cells: a primitive mammalian neural stem cell stage acquired through a default mechanism. Neuron30, 65–78 (2001). ArticleCASPubMed Google Scholar
Kawasaki, H. et al. Induction of midbrain dopaminergic neurons from ES cells by stromal cell-derived inducing activity. Neuron28, 31–40 (2000). ArticleCASPubMed Google Scholar
Ying, Q.L., Stavridis, M., Griffiths, D., Li, M. & Smith, A. Conversion of embryonic stem cells into neuroectodermal precursors in adherent monoculture. Nat. Biotechnol.21, 183–186 (2003). ArticleCASPubMed Google Scholar
Lee, S.H., Lumelsky, N., Studer, L., Auerbach, J.M. & McKay, R.D. Efficient generation of midbrain and hindbrain neurons from mouse embryonic stem cells. Nat. Biotechnol.18, 675–679 (2000). ArticleCASPubMed Google Scholar
Barberi, T. et al. Neural subtype specification of fertilization and nuclear transfer embryonic stem cells and application in parkinsonian mice. Nat. Biotechnol.21, 1200–1207 (2003). ArticleCASPubMed Google Scholar
Wichterle, H., Lieberam, I., Porter, J.A. & Jessell, T.M. Directed differentiation of embryonic stem cells into motor neurons. Cell110, 385–397 (2002). ArticleCASPubMed Google Scholar
Thomson, J.A. et al. Embryonic stem cell lines derived from human blastocysts. Science282, 1145–1147 (1998). ArticleCASPubMed Google Scholar
Zhang, S.C., Wernig, M., Duncan, I.D., Brustle, O. & Thomson, J.A. In vitro differentiation of transplantable neural precursors from human embryonic stem cells. Nat. Biotechnol.19, 1129–1133 (2001). ArticleCASPubMed Google Scholar
Pevny, L.H., Sockanathan, S., Placzek, M. & Lovell-Badge, R. A role for SOX1 in neural determination. Development125, 1967–1978 (1998). CASPubMed Google Scholar
Stern, C.D. Initial patterning of the central nervous system: how many organizers? Nat. Rev. Neurosci.2, 92–98 (2001). ArticleCASPubMed Google Scholar
Lu, Q.R. et al. Common developmental requirement for Olig function indicates a motor neuron/oligodendrocyte connection. Cell109, 75–86 (2002). ArticleCASPubMed Google Scholar
Zhou, Q., Choi, G. & Anderson, D.J. The bHLH transcription factor Olig2 promotes oligodendrocyte differentiation in collaboration with Nkx2.2. Neuron31, 791–807 (2001). ArticleCASPubMed Google Scholar
Shirasaki, R. & Pfaff, S.L. Transcriptional codes and the control of neuronal identity. Annu. Rev. Neurosci.25, 251–281 (2002). ArticleCASPubMed Google Scholar
Arber, S. et al. Requirement for the homeobox gene Hb9 in the consolidation of motor neuron identity. Neuron23, 659–674 (1999). ArticleCASPubMed Google Scholar
Lumsden, A. & Krumlauf, R. Patterning the vertebrate neuraxis. Science274, 1109–1115 (1996). ArticleCASPubMed Google Scholar
Liu, J.P., Laufer, E. & Jessell, T.M. Assigning the positional identity of spinal motor neurons: rostrocaudal patterning of Hox-c expression by FGFs, Gdf11, and retinoids. Neuron32, 997–1012 (2001). ArticleCASPubMed Google Scholar
Gao, B.X., Cheng, G. & Ziskind-Conhaim, L. Development of spontaneous synaptic transmission in the rat spinal cord. J. Neurophysiol.79, 2277–2287 (1998). ArticleCASPubMed Google Scholar