Direct proteomic mapping of the lung microvascular endothelial cell surface in vivo and in cell culture (original) (raw)

References

  1. Schnitzer, J.E. Update on the cellular and molecular basis of capillary permeability. Trends Cardiovasc. Med. 3, 124–130 (1993).
    Article CAS PubMed Google Scholar
  2. Michiels, C. Endothelial cell functions. J. Cell. Physiol. 196, 430–443 (2003).
    Article CAS PubMed Google Scholar
  3. Madri, J.A. & Williams, S.K. Capillary endothelial cell culture: Phenotype modulation by matrix components. J. Cell Biol. 97, 153–165 (1983).
    Article CAS PubMed Google Scholar
  4. Goerdt, S. et al. Characterization and differential expression of an endothelial cell- specific surface antigen in continuous and sinusoidal endothelial, in skin vascular lesions and in vitro. Exp. Cell Biol. 57, 185–192 (1989).
    CAS PubMed Google Scholar
  5. Gumkowski, F., Kaminska, G., Kaminski, M., Morrissey, L.W. & Auerbach, R. Heterogeneity of mouse vascular endothelium. Blood Vessels 24, 11–23 (1987).
    CAS PubMed Google Scholar
  6. Aird, W.C. et al. Vascular bed-specific expression of an endothelial cell gene is programmed by the tissue microenvironment. J. Cell Biol. 138, 1117–1124 (1997).
    Article CAS PubMed PubMed Central Google Scholar
  7. Janzer, R.C. & Raff, M.C. Astrocytes induce blood-brain barrier properties in endothelial cells. Nature 325, 253–257 (1987).
    Article CAS PubMed Google Scholar
  8. Stewart, P.A. & Wiley, M.J. Developing nervous tissue induces formation of blood-brain barrier characteristics in invading endothelial cells: a study using quail-chick transplantation chimeras. Dev. Biol. 84, 183–192 (1981).
    Article CAS PubMed Google Scholar
  9. Auerbach, R., Alby, L., Morrissey, L.W., Tu, M. & Joseph, J. Expression of organ-specific antigens on capillary endothelial cells. Microvasc. Res. 29, 401–411 (1985).
    Article CAS PubMed Google Scholar
  10. St. Croix, B. et al. Genes expressed in human tumor endothelium. Science 289, 1197–1202 (2000).
    Article CAS PubMed Google Scholar
  11. Obermeyer, N., Janson, N., Bergmann, J., Buck, F. & Ito, W.D. Proteome analysis of migrating versus nonmigrating rat heart endothelial cells reveals distinct expression patterns. Endothelium 10, 167–178 (2003).
    Article CAS PubMed Google Scholar
  12. Bruneel, A. et al. Proteomic study of human umbilical vein endothelial cells in culture. Proteomics 3, 714–723 (2003).
    Article CAS PubMed Google Scholar
  13. Pasqualini, R. & Ruoslahti, E. Organ targeting in vivo using phage display peptide libraries. Nature 380, 364–366 (1996).
    Article CAS PubMed Google Scholar
  14. Rajotte, D. et al. Molecular heterogeneity of the vascular endothelium revealed by in vivo phage display. J. Clin. Invest. 102, 430–437 (1998).
    Article CAS PubMed PubMed Central Google Scholar
  15. Schnitzer, J.E., McIntosh, D.P., Dvorak, A.M., Liu, J. & Oh, P. Separation of caveolae from associated microdomains of GPI-anchored proteins. Science 269, 1435–1439 (1995).
    Article CAS PubMed Google Scholar
  16. Oh, P. & Schnitzer, J.E. Isolation and subfractionation of plasma membranes to purify caveolae seperately from glycosyl-phosphatidylinositol-anchored protein microdomain in Cell Biology: A Laboratory Handbook, vol. 2 (ed. Celis, J..) 34–45 (Academic Press, Orlando, 1998).
    Google Scholar
  17. Rizzo, V., Morton, C., DePaola, N., Schnitzer, J.E. & Davies, P.F. Recruitment of endothelial caveolae into mechanotransduction pathways by flow conditioning in vitro. Am. J. Physiol. Heart Circ. Physiol. 285, H1720–H1729 (2003).
    Article CAS PubMed Google Scholar
  18. Schnitzer, J.E., Liu, J. & Oh, P. Endothelial caveolae have the molecular transport machinery for vesicle budding, docking, and fusion including VAMP, NSF, SNAP, annexins, and GTPases. J. Biol. Chem. 270, 14399–14404 (1995).
    Article CAS PubMed Google Scholar
  19. Schnitzer, J.E. & Oh, P. Aquaporin-1 in plasma membrane and caveolae provides mercury-sensitive water channels across lung endothelium. Am. J. Physiol. 270, H416–H422 (1996).
    CAS PubMed Google Scholar
  20. Schnitzer, J.E. & Oh, P. Antibodies to SPARC inhibit albumin binding to SPARC, gp60, and microvascular endothelium. Am. J. Physiol. 263, H1872–H1879 (1992).
    CAS PubMed Google Scholar
  21. Wolters, D.A., Washburn, M.P. & Yates, J.R., III. An automated multidimensional protein identification technology for shotgun proteomics. Anal. Chem. 73, 5683–5690 (2001).
    Article CAS PubMed Google Scholar
  22. Jeffries, W.A. et al. Transferrin receptor on endothelium of brain capillaries. Nature 312, 162–163 (1984).
    Article Google Scholar
  23. Schnitzer, J.E. & Oh, P. Albondin-mediated capillary permeability to albumin. Differential role of receptors in endothelial transcytosis and endocytosis of native and modified albumins. J. Biol. Chem. 269, 6072–6082 (1994).
    CAS PubMed Google Scholar
  24. Schnitzer, J.E. gp60 is an albumin-binding glycoprotein expressed by continuous endothelium involved in albumin transcytosis. Am. J. Physiol. 262, H246–H254 (1992).
    CAS PubMed Google Scholar
  25. Christian, S. et al. Nucleolin expressed at the cell surface is a marker of endothelial cells in angiogenic blood vessels. J. Cell Biol. 163, 871–878 (2003).
    Article CAS PubMed PubMed Central Google Scholar
  26. Negrutskii, B.S. & El'skaya, A.V. Eukaryotic translation elongation factor 1 alpha: structure, expression, functions, and possible role in aminoacyl-tRNA channeling. Prog. Nucleic Acid Res. Mol. Biol. 60, 47–78 (1998).
    Article CAS PubMed Google Scholar
  27. Honscha, W., Ottallah, M., Kistner, A., Platte, H. & Petzinger, E. A membrane-bound form of protein disulfide isomerase (PDI) and the hepatic uptake of organic anions. Biochim. Biophys. Acta 1153, 175–183 (1993).
    Article CAS PubMed Google Scholar
  28. Hebert, C. et al. Cell surface colligin/Hsp47 associates with tetraspanin protein CD9 in epidermoid carcinoma cell lines. J. Cell. Biochem. 73, 248–258 (1999).
    Article CAS PubMed Google Scholar
  29. Schnitzer, J. The endothelial cell surface and caveolae in health and disease. in Vascular Endothelium: Physiology, Pathology and Therapeutic Opportunities (eds. Born, G.V.R. & Schwartz, C.J.) 77–95 (1997).
    Google Scholar
  30. Washburn, M.P., Wolters, D. & Yates, J.R. III. Large-scale analysis of the yeast proteome by multidimensional protein identification technology. Nat. Biotechnol. 19, 242–247 (2001).
    Article CAS PubMed Google Scholar
  31. McIntosh, D.P., Tan, X.Y., Oh, P. & Schnitzer, J.E. Targeting endothelium and its dynamic caveolae for tissue-specific transcytosis in vivo: a pathway to overcome cell barriers to drug and gene delivery. Proc. Natl. Acad. Sci. USA 99, 1996–2001 (2002).
    Article CAS PubMed PubMed Central Google Scholar
  32. Carver, L.A. & Schnitzer, J.E. Caveolae: mining little caves for new cancer targets. Nat. Rev. Cancer 3, 571–581 (2003).
    Article CAS PubMed Google Scholar
  33. Weinman, E.J., Steplock, D. & Shenolikar, S. Acute regulation of NHE3 by protein kinase A requires a multiprotein signal complex. Kidney Int. 60, 450–454 (2001).
    Article CAS PubMed Google Scholar
  34. Abe, J., Suzuki, H., Notoya, M., Yamamoto, T. & Hirose, S. Ig-hepta, a novel member of the G protein-coupled hepta-helical receptor (GPCR) family that has immunoglobulin-like repeats in a long N-terminal extracellular domain and defines a new subfamily of GPCRs. J. Biol. Chem. 274, 19957–19964 (1999).
    Article CAS PubMed Google Scholar
  35. van der Merwe, P.A. et al. The NH2-terminal domain of rat CD2 binds rat CD48 with a low affinity and binding does not require glycosylation of CD2. Eur. J. Immunol. 23, 1373–1377 (1993).
    Article CAS PubMed Google Scholar
  36. Magee, J.C., Stone, A.E., Oldham, K.T. & Guice, K.S. Isolation, culture, and characterization of rat lung microvascular endothelial cells. Am. J. Physiol. 267, L433–L441 (1994).
    CAS PubMed Google Scholar
  37. Link, A.J. et al. Direct analysis of protein complexes using mass spectrometry. Nat. Biotechnol. 17, 676–682 (1999).
    Article CAS PubMed Google Scholar
  38. Eng, J. & McCormac, A. & Yates, J.R. An approach to correlate tandem mass spectral data of peptides with amino acid sequences in a protein database. J. Am. Soc. Mass Spectrom. 5, 976–989 (1994).
    Article CAS PubMed Google Scholar
  39. Tabb, D.L., McDonald, W.H. & Yates, J.R. III. DTASelect and Contrast: tools for assembling and comparing protein identifications from shotgun proteomics. J. Proteome Res. 1, 21–26 (2002).
    Article CAS PubMed PubMed Central Google Scholar

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