Multiple loci on 8q24 associated with prostate cancer susceptibility (original) (raw)
References
- Amundadottir, L.T. et al. Nat. Genet. 38, 652–658 (2006).
Article CAS Google Scholar - Freedman, M.L. et al. Proc. Natl. Acad. Sci. USA 103, 14068–14073 (2006).
Article CAS Google Scholar - Gudmundsson, J. et al. Nat. Genet. 39, 631–637 (2007).
Article CAS Google Scholar - Haiman, C.A. et al. Nat. Genet. 39, 638–644 (2007).
Article CAS Google Scholar - Robbins, C. et al. Genome Res. 17, 1717–1722 (2007).
Article CAS Google Scholar - Witte, J.S. Nat. Genet. 39, 579–580 (2007).
Article CAS Google Scholar - Yeager, M. et al. Nat. Genet. 39, 645–649 (2007).
Article CAS Google Scholar - Zheng, S.L. et al. J. Natl. Cancer Inst. 99, 1525–1533 (2007).
Article CAS Google Scholar - Eeles, R.A. et al. Nat. Genet. 40, 316–321 (2008).
Article CAS Google Scholar - Easton, D.F. et al. Nature 447, 1087–1093 (2007).
Article CAS Google Scholar - Ghoussaini, M. et al. J. Natl. Cancer Inst. 100, 962–966 (2008).
Article CAS Google Scholar - Yeager, M. et al. Hum. Genet. 124, 161–170 (2008).
Article CAS Google Scholar - Pomerantz, M.M. et al. Cancer Res. 69, 5568–5574 (2009).
Article CAS Google Scholar - Pomerantz, M.M. et al. Nat. Genet. 41, 882–884 (2009).
Article CAS Google Scholar - Tuupanen, S. et al. Nat. Genet. 41, 885–890 (2009).
Article CAS Google Scholar
Acknowledgements
Acknowledgments are presented in the Supplementary Note.
Author information
Author notes
- Rosalind A Eeles and Douglas F Easton: These authors contributed equally to this work.
Authors and Affiliations
- Cancer Research UK Genetic Epidemiology Unit, University of Cambridge, Cambridge, UK
Ali Amin Al Olama, Jonathan Morrison & Douglas F Easton - The Institute of Cancer Research, Surrey, Sutton, UK
Zsofia Kote-Jarai, Michelle Guy, Daniel A Leongamornlert, Malgorzata Tymrakiewicz, Sameer Jhavar, Ed Saunders, David P Dearnaley, Amanda L Hall, Lynne T O'Brien, Rosemary A Wilkinson, Emma Sawyer, Alan Horwich, Robert A Huddart, Vincent S Khoo, Christopher C Parker, Colin Cooper & Rosalind A Eeles - Cancer Epidemiology Centre, The Cancer Council Victoria, Carlton, Victoria, Australia
Graham G Giles & Gianluca Severi - Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, The University of Melbourne, Carlton, Victoria, Australia
Graham G Giles, Gianluca Severi, John L Hopper & Dallas R English - Department of Pathology, Genetic Epidemiology Laboratory, The University of Melbourne, Parkville, Victoria, Australia
Melissa C Southey - University of Nottingham Medical School, Queens Medical Centre, Nottingham, UK
Kenneth R Muir & Artitaya Lophatananon - The Royal Marsden National Health Service Foundation Trust, Sutton, Surrey, London, UK
David P Dearnaley, Audrey T Ardern-Jones, Amanda L Hall, Alan Horwich, Robert A Huddart, Vincent S Khoo, Christopher C Parker, Christopher J Woodhouse, Alan Thompson, Tim Christmas, Chris Ogden & Rosalind A Eeles - Department of Social Medicine, University of Bristol, Bristol, UK
Jenny L Donovan - Nuffield Department of Surgery, University of Oxford, Oxford, UK
Freddie C Hamdy - Cancer Research UK Cambridge Research Institute, Li Ka Shing Centre, Cambridge, UK
David E Neal - Departments of Oncology and Surgery, Surgical Oncology (Uro-Oncology), University of Cambridge, Addenbrooke's Hospital, Cambridge, UK
David E Neal
Authors
- Ali Amin Al Olama
You can also search for this author inPubMed Google Scholar - Zsofia Kote-Jarai
You can also search for this author inPubMed Google Scholar - Graham G Giles
You can also search for this author inPubMed Google Scholar - Michelle Guy
You can also search for this author inPubMed Google Scholar - Jonathan Morrison
You can also search for this author inPubMed Google Scholar - Gianluca Severi
You can also search for this author inPubMed Google Scholar - Daniel A Leongamornlert
You can also search for this author inPubMed Google Scholar - Malgorzata Tymrakiewicz
You can also search for this author inPubMed Google Scholar - Sameer Jhavar
You can also search for this author inPubMed Google Scholar - Ed Saunders
You can also search for this author inPubMed Google Scholar - John L Hopper
You can also search for this author inPubMed Google Scholar - Melissa C Southey
You can also search for this author inPubMed Google Scholar - Kenneth R Muir
You can also search for this author inPubMed Google Scholar - Dallas R English
You can also search for this author inPubMed Google Scholar - David P Dearnaley
You can also search for this author inPubMed Google Scholar - Audrey T Ardern-Jones
You can also search for this author inPubMed Google Scholar - Amanda L Hall
You can also search for this author inPubMed Google Scholar - Lynne T O'Brien
You can also search for this author inPubMed Google Scholar - Rosemary A Wilkinson
You can also search for this author inPubMed Google Scholar - Emma Sawyer
You can also search for this author inPubMed Google Scholar - Artitaya Lophatananon
You can also search for this author inPubMed Google Scholar - Alan Horwich
You can also search for this author inPubMed Google Scholar - Robert A Huddart
You can also search for this author inPubMed Google Scholar - Vincent S Khoo
You can also search for this author inPubMed Google Scholar - Christopher C Parker
You can also search for this author inPubMed Google Scholar - Christopher J Woodhouse
You can also search for this author inPubMed Google Scholar - Alan Thompson
You can also search for this author inPubMed Google Scholar - Tim Christmas
You can also search for this author inPubMed Google Scholar - Chris Ogden
You can also search for this author inPubMed Google Scholar - Colin Cooper
You can also search for this author inPubMed Google Scholar - Jenny L Donovan
You can also search for this author inPubMed Google Scholar - Freddie C Hamdy
You can also search for this author inPubMed Google Scholar - David E Neal
You can also search for this author inPubMed Google Scholar - Rosalind A Eeles
You can also search for this author inPubMed Google Scholar - Douglas F Easton
You can also search for this author inPubMed Google Scholar
Consortia
The UK Genetic Prostate Cancer Study Collaborators/British Association of Urological Surgeons' Section of Oncology
The UK Prostate testing for cancer and Treatment study (ProtecT Study) Collaborators
Contributions
A.A.A.O. and D.F.E. performed the statistical analysis and drafted the manuscript with major input from R.A.E. and Z.K.-J. R.A.E. and D.F.E. are joint PIs on this study. M.G. provided data management for the UK Genetic Prostate Cancer Study study. J.M. provided database and bioinformatics support. G.G.G., J.L.H. and D.R.E. are principal investigators (PIs) of the Australian studies; J.L.D., F.C.H. and D.E.N. are joint PIs of ProtecT. M.C.S. led the Australian genotyping. G.S. coordinated the Australian studies. Z.K.-J coordinated the genotyping in stage 2 with support from D.A.L., M.T., S.J. and E.S. K.R.M. and R.A.E. are joint PIs of the Prostate Cancer Research Fund study. D.P.D., A.T.A.-J., A.L.H., L.T.O'B., R.A.W., E.S., A.L., A.H., R.A.H., V.S.K., C.C.P., C.J.W., A.T., T.C., C.O. and C.C. identified and collected clinical material, processed samples, undertook genotyping or collated data. Other members of The UK Genetic Prostate Cancer Study Collaborators/British Association of Urological Surgeons' Section of Oncology and The UK ProtecT Study Collaborators, listed in the Supplementary Note, collected clinical samples and provided data management support.
Corresponding author
Correspondence toDouglas F Easton.
Additional information
Full lists of members are provided in the Supplementary Note.
Full lists of members are provided in the Supplementary Note.
Supplementary information
Rights and permissions
About this article
Cite this article
Al Olama, A., Kote-Jarai, Z., Giles, G. et al. Multiple loci on 8q24 associated with prostate cancer susceptibility.Nat Genet 41, 1058–1060 (2009). https://doi.org/10.1038/ng.452
- Received: 06 July 2009
- Accepted: 25 August 2009
- Published: 20 September 2009
- Issue Date: October 2009
- DOI: https://doi.org/10.1038/ng.452