Multiple loci on 8q24 associated with prostate cancer susceptibility (original) (raw)

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Acknowledgements

Acknowledgments are presented in the Supplementary Note.

Author information

Author notes

  1. Rosalind A Eeles and Douglas F Easton: These authors contributed equally to this work.

Authors and Affiliations

  1. Cancer Research UK Genetic Epidemiology Unit, University of Cambridge, Cambridge, UK
    Ali Amin Al Olama, Jonathan Morrison & Douglas F Easton
  2. The Institute of Cancer Research, Surrey, Sutton, UK
    Zsofia Kote-Jarai, Michelle Guy, Daniel A Leongamornlert, Malgorzata Tymrakiewicz, Sameer Jhavar, Ed Saunders, David P Dearnaley, Amanda L Hall, Lynne T O'Brien, Rosemary A Wilkinson, Emma Sawyer, Alan Horwich, Robert A Huddart, Vincent S Khoo, Christopher C Parker, Colin Cooper & Rosalind A Eeles
  3. Cancer Epidemiology Centre, The Cancer Council Victoria, Carlton, Victoria, Australia
    Graham G Giles & Gianluca Severi
  4. Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, The University of Melbourne, Carlton, Victoria, Australia
    Graham G Giles, Gianluca Severi, John L Hopper & Dallas R English
  5. Department of Pathology, Genetic Epidemiology Laboratory, The University of Melbourne, Parkville, Victoria, Australia
    Melissa C Southey
  6. University of Nottingham Medical School, Queens Medical Centre, Nottingham, UK
    Kenneth R Muir & Artitaya Lophatananon
  7. The Royal Marsden National Health Service Foundation Trust, Sutton, Surrey, London, UK
    David P Dearnaley, Audrey T Ardern-Jones, Amanda L Hall, Alan Horwich, Robert A Huddart, Vincent S Khoo, Christopher C Parker, Christopher J Woodhouse, Alan Thompson, Tim Christmas, Chris Ogden & Rosalind A Eeles
  8. Department of Social Medicine, University of Bristol, Bristol, UK
    Jenny L Donovan
  9. Nuffield Department of Surgery, University of Oxford, Oxford, UK
    Freddie C Hamdy
  10. Cancer Research UK Cambridge Research Institute, Li Ka Shing Centre, Cambridge, UK
    David E Neal
  11. Departments of Oncology and Surgery, Surgical Oncology (Uro-Oncology), University of Cambridge, Addenbrooke's Hospital, Cambridge, UK
    David E Neal

Authors

  1. Ali Amin Al Olama
  2. Zsofia Kote-Jarai
  3. Graham G Giles
  4. Michelle Guy
  5. Jonathan Morrison
  6. Gianluca Severi
  7. Daniel A Leongamornlert
  8. Malgorzata Tymrakiewicz
  9. Sameer Jhavar
  10. Ed Saunders
  11. John L Hopper
  12. Melissa C Southey
  13. Kenneth R Muir
  14. Dallas R English
  15. David P Dearnaley
  16. Audrey T Ardern-Jones
  17. Amanda L Hall
  18. Lynne T O'Brien
  19. Rosemary A Wilkinson
  20. Emma Sawyer
  21. Artitaya Lophatananon
  22. Alan Horwich
  23. Robert A Huddart
  24. Vincent S Khoo
  25. Christopher C Parker
  26. Christopher J Woodhouse
  27. Alan Thompson
  28. Tim Christmas
  29. Chris Ogden
  30. Colin Cooper
  31. Jenny L Donovan
  32. Freddie C Hamdy
  33. David E Neal
  34. Rosalind A Eeles
  35. Douglas F Easton

Consortia

The UK Genetic Prostate Cancer Study Collaborators/British Association of Urological Surgeons' Section of Oncology

The UK Prostate testing for cancer and Treatment study (ProtecT Study) Collaborators

Contributions

A.A.A.O. and D.F.E. performed the statistical analysis and drafted the manuscript with major input from R.A.E. and Z.K.-J. R.A.E. and D.F.E. are joint PIs on this study. M.G. provided data management for the UK Genetic Prostate Cancer Study study. J.M. provided database and bioinformatics support. G.G.G., J.L.H. and D.R.E. are principal investigators (PIs) of the Australian studies; J.L.D., F.C.H. and D.E.N. are joint PIs of ProtecT. M.C.S. led the Australian genotyping. G.S. coordinated the Australian studies. Z.K.-J coordinated the genotyping in stage 2 with support from D.A.L., M.T., S.J. and E.S. K.R.M. and R.A.E. are joint PIs of the Prostate Cancer Research Fund study. D.P.D., A.T.A.-J., A.L.H., L.T.O'B., R.A.W., E.S., A.L., A.H., R.A.H., V.S.K., C.C.P., C.J.W., A.T., T.C., C.O. and C.C. identified and collected clinical material, processed samples, undertook genotyping or collated data. Other members of The UK Genetic Prostate Cancer Study Collaborators/British Association of Urological Surgeons' Section of Oncology and The UK ProtecT Study Collaborators, listed in the Supplementary Note, collected clinical samples and provided data management support.

Corresponding author

Correspondence toDouglas F Easton.

Additional information

Full lists of members are provided in the Supplementary Note.

Full lists of members are provided in the Supplementary Note.

Supplementary information

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Al Olama, A., Kote-Jarai, Z., Giles, G. et al. Multiple loci on 8q24 associated with prostate cancer susceptibility.Nat Genet 41, 1058–1060 (2009). https://doi.org/10.1038/ng.452

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