Genome-wide association identifies a susceptibility locus for coronary artery disease in the Chinese Han population (original) (raw)

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Acknowledgements

We thank the study subjects for their participation in and support of this project. We greatly appreciate the generous help from L. Li, G.Q. Shen, Y.J. Qian, F. Xu, F.C. Sun, F.S. Ji, B. Liu, X.Y. Zhou, Y. Xiao, S. Rao and B. Yang. This study was supported by China National 863 Scientific Program (2006AA02Z476), the China National Basic Research Program (973 program 2007CB512002), a Hubei Province Natural Science Key Program (2008CDA047), a Key Academic Program Leader Award of Wuhan City (200951830560), the National Natural Science Foundation of China (30670857, 30800457 and 81070106) and in part by the Center for Cardiovascular Genetics, Department of Molecular Cardiology, Lerner Research Institute, Cleveland Clinic.

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Author notes

1. Fan Wang, Cheng-Qi Xu, Qing He, Jian-Ping Cai, Xiu-Chun Li, Dan Wang, Xin Xiong, Yu-Hua Liao, Qiu-Tang Zeng, Yan-Zong Yang and Xiang Cheng: These authors contributed equally to this work.

Authors and Affiliations

1. Key Laboratory of Molecular Biophysics of the Ministry of Education, Cardio-X Institute, College of Life Science and Technology and Center for Human Genome Research, Huazhong University of Science and Technology, Wuhan, China
   Fan Wang, Cheng-Qi Xu, Xiu-Chun Li, Dan Wang, Xin Xiong, Cong Li, Rong Yang, Chu-Chu Wang, Qiu-Lun Lu, Ying Bai, Yu-Feng Huang, Dan Yin, Qing Yang, Xiao-Jing Wang, Si-Si Li, Yuan-Yuan Zhao, Fen-Fen Fu, Yuan Huang, Nan Wang, Chun-Yan Luo, Li-Ying Ji, Lei Li, Hui Liu, Er-Wen Huang, Jin Cui, Xiang Ren, Hui Li, Tie Ke, Xian-Qin Zhang, Jing-Yu Liu, Mu-Gen Liu, Li-Song Shi, Xin Tu & Qing K Wang
2. Beijing Hospital, Ministry of Health, Beijing, China
   Qing He, Jian-Ping Cai, Da-Peng Dai & Na Jia
3. Institute of Cardiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
   Yu-Hua Liao, Qiu-Tang Zeng & Xiang Cheng
4. First Affiliated Hospital of Dalian Medical University, Dalian, China
   Yan-Zong Yang, Rong-Feng Zhang, Lian-Jun Gao & Yun-Long Xia
5. Renmin Hospital of Wuhan University, Wuhan, China
   Gang Wu, Hao Xia & Bo Yang
6. Zhongnan Hospital of Wuhan University, Wuhan, China
   Jing Wan & Jiang-Hua Ren
7. Affiliated Hospital of Jining Medical Collage, Shandong, China
   Qing-Xian Li, Sheng-Wei Shi & Nan Lin
8. Department of Pharmacology, Harbin Medical University, Harbin, China
   Zhen-Wei Pan
9. The First Affiliated Hospital, Harbin Medical University, Harbin, China
   Yue Li
10. The Second Affiliated Hospital, Harbin Medical University, Harbin, China
    Bo Yu
11. The First Hospital of Wuhan City, Wuhan, China
    Yan-Xia Wu, Yu-He Ke & Jian Lei

Authors

1. Fan Wang
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2. Cheng-Qi Xu
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3. Qing He
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4. Jian-Ping Cai
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5. Xiu-Chun Li
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6. Dan Wang
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7. Xin Xiong
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8. Yu-Hua Liao
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9. Qiu-Tang Zeng
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10. Yan-Zong Yang
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11. Xiang Cheng
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12. Cong Li
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13. Rong Yang
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14. Chu-Chu Wang
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15. Gang Wu
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16. Qiu-Lun Lu
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17. Ying Bai
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18. Yu-Feng Huang
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19. Dan Yin
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20. Qing Yang
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21. Xiao-Jing Wang
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22. Da-Peng Dai
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23. Rong-Feng Zhang
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24. Jing Wan
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25. Jiang-Hua Ren
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26. Si-Si Li
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27. Yuan-Yuan Zhao
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28. Fen-Fen Fu
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29. Yuan Huang
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30. Qing-Xian Li
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31. Sheng-Wei Shi
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32. Nan Lin
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33. Zhen-Wei Pan
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34. Yue Li
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35. Bo Yu
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36. Yan-Xia Wu
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37. Yu-He Ke
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38. Jian Lei
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39. Nan Wang
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40. Chun-Yan Luo
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41. Li-Ying Ji
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42. Lian-Jun Gao
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43. Lei Li
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44. Hui Liu
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45. Er-Wen Huang
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46. Jin Cui
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47. Na Jia
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48. Xiang Ren
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49. Hui Li
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50. Tie Ke
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51. Xian-Qin Zhang
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52. Jing-Yu Liu
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53. Mu-Gen Liu
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54. Hao Xia
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55. Bo Yang
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56. Li-Song Shi
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57. Yun-Long Xia
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58. Xin Tu
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59. Qing K Wang
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Contributions

Study concept and design: Q.K.W., J.-P.C., X.T., Q.H. and M.-G.L.

Acquisition of data: C.-Q.X., Q.H., J.-P.C., X.-C.L., D.W., X.X., Y.-H.L., Q.-T.Z., X.C., Y.-Z.Y., C.L., R.Y., C.-C.W., G.W., Q.-L.L., Y.B., Y.-F.H., D.Y., Q.Y., X.-J.W., D.-P.D., R.-F.Z., J.W., J.-H.R., S.-S.L., Y.-Y.Z., F.-F.F., Y.H., Q.-X.L., S.-W.S., N.L., Z.-W.P., Y.L., B.Y., Y.-X.W., Y.-H.K., J.L., N.W., C.-Y.L., L.-Y.J., L.-J.G., L.L., H. Liu, E.-W.H., J.C., N.J., X.R., H. Li, T.K., X.-Q.Z., J.-Y.L., H.X., B.Y., L.-S.S. and Y.-L.X.

Analysis and interpretation of data: C.-Q.X., F.W., D.-P.D., J.-P.C., L.-S.S., X.-C.L., D.W., X.X., Q.H., X.T. and Q.K.W.

Drafting of the manuscript: C.-Q.X., F.W. and X.T.

Critical revision of the manuscript: Q.K.W., F.W. and C.-Q.X.

Statistical analysis: F.W. and C.-Q.X.

Study supervision: Q.K.W., Q.H., J.-P.C., X.T., Y.-H.L. and Y.-Z.Y.

Corresponding authors

Correspondence toXin Tu or Qing K Wang.

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Competing interests

The authors declare no competing financial interests.

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Wang, F., Xu, CQ., He, Q. et al. Genome-wide association identifies a susceptibility locus for coronary artery disease in the Chinese Han population.Nat Genet 43, 345–349 (2011). https://doi.org/10.1038/ng.783

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• Received: 07 October 2010
• Accepted: 10 February 2011
• Published: 06 March 2011
• Issue Date: April 2011
• DOI: https://doi.org/10.1038/ng.783