Population structure, differential bias and genomic control in a large-scale, case-control association study (original) (raw)

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Acknowledgements

We thank the individuals with T1D and control individuals for their participation; G. Coleman, S. Field, T. Mistry, K. Bourget, S. Clayton, M. Hardy, P. Lauder, M. Maisuria, W. Meadows and S. Wood for preparing DNA samples; D. Strachan, R. Jones, S. Ring and W. McArdle for providing DNA from the 1958 British Birth Cohort collection; and A. Long, N. Naclerio, T. Cormier, K. Tran, C. Bruckner and S. Picton for genotyping and technical assistance. We acknowledge use of DNA from the 1958 British Birth Cohort collection, funded by the Medical Research Council and the Wellcome Trust. We thank the Juvenile Diabetes Research Foundation, the Wellcome Trust, Diabetes UK and the Medical Research Council for financial support. D.G.C. is a Juvenile Diabetes Research Foundation and Wellcome Trust Principal Research Fellow.

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Authors and Affiliations

  1. Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, University of Cambridge, Cambridge Institute for Medical Research, Wellcome Trust/MRC Building, Cambridge, CB2 2XY, UK
    David G Clayton, Neil M Walker, Deborah J Smyth, Rebecca Pask, Jason D Cooper, Lisa M Maier, Luc J Smink, Alex C Lam, Nigel R Ovington, Helen E Stevens, Sarah Nutland, Joanna M M Howson & John A Todd
  2. ParAllele BioScience, 7300 Shoreline Court, South San Francisco, California, 94080, USA
    Malek Faham, Martin Moorhead, Hywel B Jones, Matthew Falkowski, Paul Hardenbol & Thomas D Willis

Authors

  1. David G Clayton
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  2. Neil M Walker
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  3. Deborah J Smyth
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  4. Rebecca Pask
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  5. Jason D Cooper
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  6. Lisa M Maier
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  7. Luc J Smink
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  8. Alex C Lam
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  9. Nigel R Ovington
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  10. Helen E Stevens
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  11. Sarah Nutland
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  12. Joanna M M Howson
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  13. Malek Faham
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  14. Martin Moorhead
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  15. Hywel B Jones
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  16. Matthew Falkowski
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  17. Paul Hardenbol
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  18. Thomas D Willis
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  19. John A Todd
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Corresponding authors

Correspondence toDavid G Clayton or John A Todd.

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Competing interests

M. Faham, M.M., H.B.J., M. Falkowski, P.H. and T.D.W. are currently employed by ParAllele Bioscience.

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Clayton, D., Walker, N., Smyth, D. et al. Population structure, differential bias and genomic control in a large-scale, case-control association study.Nat Genet 37, 1243–1246 (2005). https://doi.org/10.1038/ng1653

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