Diet, gut microbiota and immune responses (original) (raw)

Nature Immunology volume 12, pages 5–9 (2011)Cite this article

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The fields of immunology, microbiology, nutrition and metabolism are rapidly converging. Here we expand on a diet-microbiota model as the basis for the greater incidence of asthma and autoimmunity in developed countries.

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References

  1. Turnbaugh, P.J. et al. Sci. Transl. Med. 1, 6ra14 (2009).
  2. De Filippo, C. et al. Proc. Natl. Acad. Sci. USA 107, 14691–14696 (2010).
    Article Google Scholar
  3. Wen, L. et al. Nature 455, 1109–1113 (2008).
    Article CAS Google Scholar
  4. Maslowski, K.M. et al. Nature 461, 1282–1286 (2009).
    Article CAS Google Scholar
  5. Clarke, T.B. et al. Nat. Med. 16, 228–231 (2010).
    Article CAS Google Scholar
  6. Sin, D.D. & Sutherland, E.R. Thorax 63, 1018–1023 (2008).
    Article CAS Google Scholar
  7. Patterson, C.C. et al. Lancet 373, 2027–2033 (2009).
    Article Google Scholar
  8. Noverr, M.C. & Huffnagle, G.B. Trends Microbiol. 12, 562–568 (2004).
    Article CAS Google Scholar
  9. Devereux, G. Nat. Rev. Immunol. 6, 869–874 (2006).
    Article CAS Google Scholar
  10. Duncan, S.H. et al. Appl. Environ. Microbiol. 73, 1073–1078 (2007).
    Article CAS Google Scholar
  11. Vijay-Kumar, M. et al. Science 328, 228–231 (2010).
    Article CAS Google Scholar
  12. Kalliomaki, M. et al. J. Allergy Clin. Immunol. 107, 129–134 (2001).
    Article CAS Google Scholar
  13. Eerola, E. et al. Br. J. Rheumatol. 33, 1030–1038 (1994).
    Article CAS Google Scholar
  14. Vaahtovuo, J. et al. J. Rheumatol. 35, 1500–1505 (2008).
    CAS PubMed Google Scholar
  15. Wu, H.J. et al. Immunity 32, 815–827 (2010).
    Article CAS Google Scholar
  16. Frank, D.N. et al. Proc. Natl. Acad. Sci. USA 104, 13780–13785 (2007).
    Article CAS Google Scholar
  17. Le Poul, E. et al. J. Biol. Chem. 278, 25481–25489 (2003).
    Article CAS Google Scholar
  18. Quivy, V. & Van Lint, C. Biochem. Pharmacol. 68, 1221–1229 (2004).
    Article CAS Google Scholar
  19. Hoverstad, T. & Midtvedt, T. J. Nutr. 116, 1772–1776 (1986).
    Article CAS Google Scholar
  20. Chervonsky, A.V. Nat. Immunol. 11, 28–35 (2010).
    Article CAS Google Scholar
  21. Round, J.L. & Mazmanian, S.K. Proc. Natl. Acad. Sci. USA 107, 12204–12209 (2010).
    Article CAS Google Scholar
  22. Morland, B. & Midtvedt, T. Infect. Immun. 44, 750–752 (1984).
    CAS PubMed PubMed Central Google Scholar
  23. Slavin, J. Proc. Nutr. Soc. 62, 129–134 (2003).
    Article CAS Google Scholar
  24. Devereux, G. et al. Am. J. Respir. Crit. Care Med. 174, 499–507 (2006).
    Article CAS Google Scholar
  25. Galvez, J. et al. Mol. Nutr. Food Res. 49, 601–608 (2005).
    Article Google Scholar
  26. Muller, H. et al. Scand. J. Rheumatol. 30, 1–10 (2001).
    CAS PubMed Google Scholar
  27. Simopoulos, A.P. J. Am. Coll. Nutr. 21, 495–505 (2002).
    Article CAS Google Scholar
  28. Oh da, Y. et al. Cell 142, 687–698 (2010).
    Article Google Scholar
  29. Strachan, D.P. Thorax 55 Suppl 1, S2–S10 (2000).
    Article Google Scholar
  30. Khoruts, A. et al. J. Clin. Gastroenterol. 44, 354–360 (2010).
    PubMed Google Scholar

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Authors and Affiliations

  1. and is affiliated with the Department of Medicine, Kendle M. Maslowski is with the Garvan Institute of Medical Research, Sydney, Australia, and the Cooperative Research Centre for Asthma and Airways, Sydney, Australia, St Vincent's Clinical School, University of New South Wales, Sydney, Australia.,
    Kendle M Maslowski
  2. Charles R. Mackay is with the Department of Immunology, Faculty of Medicine, Nursing and Health Sciences, Monash University, Melbourne, Australia, and the Cooperative Research Centre for Asthma and Airways, Sydney, Australia.,
    Charles R Mackay

Authors

  1. Kendle M Maslowski
  2. Charles R Mackay

Corresponding author

Correspondence toCharles R Mackay.

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The authors declare no competing financial interests.

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Maslowski, K., Mackay, C. Diet, gut microbiota and immune responses.Nat Immunol 12, 5–9 (2011). https://doi.org/10.1038/ni0111-5

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