Myeloid C-type lectins in innate immunity (original) (raw)

• Janeway, C.A., Jr. Approaching the asymptote? Evolution and revolution in immunology. Cold Spring Harb. Symp. Quant. Biol. 54, 1–13 (1989).
  CAS PubMed Google Scholar
• Kawai, T. & Akira, S. Innate immune recognition of viral infection. Nat. Immunol. 7, 131–137 (2006).
  CAS PubMed Google Scholar
• Medzhitov, R. & Janeway, C.A., Jr. Innate immunity: the virtues of a nonclonal system of recognition. Cell 91, 295–298 (1997).
  CAS PubMed Google Scholar
• Akira, S., Uematsu, S. & Takeuchi, O. Pathogen recognition and innate immunity. Cell 124, 783–801 (2006).
  CAS PubMed Google Scholar
• Crocker, P.R. Siglecs in innate immunity. Curr. Opin. Pharmacol. 5, 431–437 (2005).
  CAS PubMed Google Scholar
• Zelensky, A.N. & Gready, J.E. The C-type lectin-like domain superfamily. FEBS J 272, 6179–6217 (2005).
  CAS PubMed Google Scholar
• Geijtenbeek, T.B., van Vliet, S.J. & Engering, A., Hart, B.A. & van Kooyk, Y. Self- and nonself-recognition by C-type lectins on dendritic cells. Annu. Rev. Immunol. 22, 33–54 (2004).
  CAS PubMed Google Scholar
• Drickamer, K. C-type lectin-like domains. Curr. Opin. Struct. Biol. 9, 585–590 (1999).
  CAS PubMed Google Scholar
• O'Rourke, D., Baban, D., Demidova, M., Mott, R. & Hodgkin, J. Genomic clusters, putative pathogen recognition molecules, and antimicrobial genes are induced by infection of C. elegans with M. nematophilum. Genome Res. 16, 1005–1016 (2006).
  CAS PubMed PubMed Central Google Scholar
• Takahashi, K., Ip, W.E., Michelow, I.C. & Ezekowitz, R.A. The mannose-binding lectin: a prototypic pattern recognition molecule. Curr. Opin. Immunol. 18, 16–23 (2006).
  CAS PubMed Google Scholar
• Cash, H.L., Whitham, C.V., Behrendt, C.L. & Hooper, L.V. Symbiotic bacteria direct expression of an intestinal bactericidal lectin. Science 313, 1126–1130 (2006).
  CAS PubMed PubMed Central Google Scholar
• Lanier, L.L. NK cell recognition. Annu. Rev. Immunol. 23, 225–274 (2005).
  CAS PubMed Google Scholar
• Blander, J.M. & Medzhitov, R. Regulation of phagosome maturation by signals from Toll-like receptors. Science 304, 1014–1018 (2004).
  CAS PubMed Google Scholar
• Bonifacino, J.S. & Dell'Angelica, E.C. Molecular bases for the recognition of tyrosine-based sorting signals. J. Cell Biol. 145, 923–926 (1999).
  CAS PubMed PubMed Central Google Scholar
• Mahnke, K. et al. The dendritic cell receptor for endocytosis, DEC-205, can recycle and enhance antigen presentation via major histocompatibility complex class II-positive lysosomal compartments. J. Cell Biol. 151, 673–684 (2000).
  CAS PubMed PubMed Central Google Scholar
• Herre, J. et al. Dectin-1 uses novel mechanisms for yeast phagocytosis in macrophages. Blood 104, 4038–4045 (2004).
  CAS PubMed Google Scholar
• Rogers, N.C. et al. Syk-dependent cytokine induction by Dectin-1 reveals a novel pattern recognition pathway for C type lectins. Immunity 22, 507–517 (2005).
  CAS PubMed Google Scholar
• Underhill, D.M., Rossnagle, E., Lowell, C.A. & Simmons, R.M. Dectin-1 activates Syk tyrosine kinase in a dynamic subset of macrophages for reactive oxygen production. Blood 106, 2543–2550 (2005).
  CAS PubMed PubMed Central Google Scholar
• Gross, O. et al. Card9 controls a non-TLR signalling pathway for innate anti-fungal immunity. Nature 442, 651–656 (2006).
  CAS PubMed Google Scholar
• Engering, A. et al. The dendritic cell-specific adhesion receptor DC-SIGN internalizes antigen for presentation to T cells. J. Immunol. 168, 2118–2126 (2002).
  CAS PubMed Google Scholar
• Kwon, D.S., Gregorio, G., Bitton, N., Hendrickson, W.A. & Littman, D.R. DC-SIGN-mediated internalization of HIV is required for trans-enhancement of T cell infection. Immunity 16, 135–144 (2002).
  CAS PubMed Google Scholar
• Tacken, P.J., Torensma, R. & Figdor, C.G. Targeting antigens to dendritic cells in vivo. Immunobiology 211, 599–608 (2006).
  CAS PubMed Google Scholar
• Dzionek, A. et al. BDCA-2, a novel plasmacytoid dendritic cell-specific type II C-type lectin, mediates antigen capture and is a potent inhibitor of interferon alpha/beta induction. J. Exp. Med. 194, 1823–1834 (2001).
  CAS PubMed PubMed Central Google Scholar
• Carrasco, Y.R. & Batista, F.D. B cell recognition of membrane-bound antigen: an exquisite way of sensing ligands. Curr. Opin. Immunol. 18, 286–291 (2006).
  CAS PubMed Google Scholar
• Brown, G.D. Dectin-1: a signalling non-TLR pattern-recognition receptor. Nat. Rev. Immunol. 6, 33–43 (2006).
  CAS PubMed Google Scholar
• Underhill, D.M. et al. The Toll-like receptor 2 is recruited to macrophage phagosomes and discriminates between pathogens. Nature 401, 811–815 (1999).
  CAS PubMed Google Scholar
• Edwards, A.D. et al. Microbial recognition via Toll-like receptor-dependent and -independent pathways determines the cytokine response of murine dendritic cell subsets to CD40 triggering. J. Immunol. 169, 3652–3660 (2002).
  CAS PubMed Google Scholar
• Steele, C. et al. The beta-glucan receptor dectin-1 recognizes specific morphologies of Aspergillus fumigatus. PLoS Pathog. 1, e42 (2005).
  PubMed PubMed Central Google Scholar
• Hohl, T.M. et al. Aspergillus fumigatus triggers inflammatory responses by stage-specific β-glucan display. PLoS Pathog. 1, e30 (2005).
  PubMed PubMed Central Google Scholar
• Dillon, S. et al. Yeast zymosan, a stimulus for TLR2 and dectin-1, induces regulatory antigen-presenting cells and immunological tolerance. J. Clin. Invest. 116, 916–928 (2006).
  CAS PubMed PubMed Central Google Scholar
• Colonna, M., Samaridis, J. & Angman, L. Molecular characterization of two novel C-type lectin-like receptors, one of which is selectively expressed in human dendritic cells. Eur. J. Immunol. 30, 697–704 (2000).
  CAS PubMed Google Scholar
• Suzuki-Inoue, K. et al. A novel Syk-dependent mechanism of platelet activation by the C-type lectin receptor CLEC-2. Blood 107, 542–549 (2006).
  CAS PubMed Google Scholar
• Bakker, A.B., Baker, E., Sutherland, G.R., Phillips, J.H. & Lanier, L.L. Myeloid DAP12-associating lectin (MDL)-1 is a cell surface receptor involved in the activation of myeloid cells. Proc. Natl. Acad. Sci. USA 96, 9792–9796 (1999).
  CAS PubMed PubMed Central Google Scholar
• Kanazawa, N., Tashiro, K., Inaba, K. & Miyachi, Y. Dendritic cell immunoactivating receptor, a novel C-type lectin immunoreceptor, acts as an activating receptor through association with Fc receptor γ chain. J. Biol. Chem. 278, 32645–32652 (2003).
  CAS PubMed Google Scholar
• Ravetch, J.V. & Lanier, L.L. Immune inhibitory receptors. Science 290, 84–89 (2000).
  CAS PubMed Google Scholar
• Kanazawa, N. et al. DCIR acts as an inhibitory receptor depending on its immunoreceptor tyrosine-based inhibitory motif. J. Invest. Dermatol. 118, 261–266 (2002).
  CAS PubMed Google Scholar
• Richard, M., Thibault, N., Veilleux, P., Gareau-Page, G. & Beaulieu, A.D. Granulocyte macrophage-colony stimulating factor reduces the affinity of SHP-2 for the ITIM of CLECSF6 in neutrophils: a new mechanism of action for SHP-2. Mol. Immunol. 43, 1716–1721 (2006).
  CAS PubMed Google Scholar
• Marshall, A.S. et al. Identification and characterization of a novel human myeloid inhibitory C-type lectin-like receptor (MICL) that is predominantly expressed on granulocytes and monocytes. J. Biol. Chem. 279, 14792–14802 (2004).
  CAS PubMed Google Scholar
• Barrow, A.D. & Trowsdale, J. You say ITAM and I say ITIM, let's call the whole thing off: the ambiguity of immunoreceptor signalling. Eur. J. Immunol. 36, 1646–1653 (2006).
  CAS PubMed Google Scholar
• Hamerman, J.A. & Lanier, L.L. Inhibition of immune responses by ITAM-bearing receptors. Sci. STKE 2006, re1 (2006).
  PubMed Google Scholar
• Chen, C.H. et al. Dendritic-cell-associated C-type lectin 2 (DCAL-2) alters dendritic-cell maturation and cytokine production. Blood 107, 1459–1467 (2006).
  CAS PubMed PubMed Central Google Scholar
• Geijtenbeek, T.B. et al. Mycobacteria target DC-SIGN to suppress dendritic cell function. J. Exp. Med. 197, 7–17 (2003).
  CAS PubMed PubMed Central Google Scholar
• Caparros, E. et al. DC-SIGN ligation on dendritic cells results in ERK and PI3K activation and modulates cytokine production. Blood 107, 3950–3958 (2006).
  CAS PubMed Google Scholar
• Gantner, B.N., Simmons, R.M., Canavera, S.J., Akira, S. & Underhill, D.M. Collaborative induction of inflammatory responses by dectin-1 and Toll-like receptor 2. J. Exp. Med. 197, 1107–1117 (2003).
  CAS PubMed PubMed Central Google Scholar
• Brown, G.D. et al. Dectin-1 mediates the biological effects of β-glucans. J. Exp. Med. 197, 1119–1124 (2003).
  CAS PubMed PubMed Central Google Scholar
• Napolitani, G., Rinaldi, A., Bertoni, F., Sallusto, F. & Lanzavecchia, A. Selected Toll-like receptor agonist combinations synergistically trigger a T helper type 1–polarizing program in dendritic cells. Nat. Immunol. 6, 769–776 (2005).
  CAS PubMed PubMed Central Google Scholar
• Gautier, G. et al. A type I interferon autocrine-paracrine loop is involved in Toll-like receptor-induced interleukin-12p70 secretion by dendritic cells. J. Exp. Med. 201, 1435–1446 (2005).
  CAS PubMed PubMed Central Google Scholar
• Stahl, P., Schlesinger, P.H., Sigardson, E., Rodman, J.S. & Lee, Y.C. Receptor-mediated pinocytosis of mannose glycoconjugates by macrophages: characterization and evidence for receptor recycling. Cell 19, 207–215 (1980).
  CAS PubMed Google Scholar
• Ariizumi, K. et al. Identification of a novel, dendritic cell-associated molecule, dectin-1, by subtractive cDNA cloning. J. Biol. Chem. 275, 20157–20167 (2000).
  CAS PubMed Google Scholar
• Adachi, Y. et al. Characterization of β-glucan recognition site on C-type lectin, dectin 1. Infect. Immun. 72, 4159–4171 (2004).
  CAS PubMed PubMed Central Google Scholar
• Kim, Y.S. et al. Gram-negative bacteria-binding protein, a pattern recognition receptor for lipopolysaccharide and β-1,3-glucan that mediates the signaling for the induction of innate immune genes in Drosophila melanogaster cells. J. Biol. Chem. 275, 32721–32727 (2000).
  CAS PubMed Google Scholar
• Ochiai, M. & Ashida, M. A pattern-recognition protein for β-1,3-glucan. The binding domain and the cDNA cloning of β-1,3-glucan recognition protein from the silkworm, Bombyx mori. J. Biol. Chem. 275, 4995–5002 (2000).
  CAS PubMed Google Scholar
• Gantner, B.N., Simmons, R.M. & Underhill, D.M. Dectin-1 mediates macrophage recognition of Candida albicans yeast but not filaments. EMBO J. 24, 1277–1286 (2005).
  CAS PubMed PubMed Central Google Scholar
• Kang, P.B. et al. The human macrophage mannose receptor directs Mycobacterium tuberculosis lipoarabinomannan-mediated phagosome biogenesis. J. Exp. Med. 202, 987–999 (2005).
  CAS PubMed PubMed Central Google Scholar
• Bergman, M.P. et al. Helicobacter pylori modulates the T helper cell 1/T helper cell 2 balance through phase-variable interaction between lipopolysaccharide and DC-SIGN. J. Exp. Med. 200, 979–990 (2004).
  CAS PubMed PubMed Central Google Scholar
• Swain, S.D., Lee, S.J., Nussenzweig, M.C. & Harmsen, A.G. Absence of the macrophage mannose receptor in mice does not increase susceptibility to Pneumocystis carinii infection in vivo. Infect. Immun. 71, 6213–6221 (2003).
  CAS PubMed PubMed Central Google Scholar
• Lee, S.J., Zheng, N.Y., Clavijo, M. & Nussenzweig, M.C. Normal host defense during systemic candidiasis in mannose receptor-deficient mice. Infect. Immun. 71, 437–445 (2003).
  CAS PubMed PubMed Central Google Scholar
• Mi, Y., Shapiro, S.D. & Baenziger, J.U. Regulation of lutropin circulatory half-life by the mannose/_N_-acetylgalactosamine-4–SO4 receptor is critical for implantation in vivo. J. Clin. Invest. 109, 269–276 (2002).
  CAS PubMed PubMed Central Google Scholar
• van Gisbergen, K.P., Sanchez-Hernandez, M., Geijtenbeek, T.B. & van Kooyk, Y. Neutrophils mediate immune modulation of dendritic cells through glycosylation-dependent interactions between Mac-1 and DC-SIGN. J. Exp. Med. 201, 1281–1292 (2005).
  CAS PubMed PubMed Central Google Scholar
• van Gisbergen, K.P., Ludwig, I.S., Geijtenbeek, T.B. & van Kooyk, Y. Interactions of DC-SIGN with Mac-1 and CEACAM1 regulate contact between dendritic cells and neutrophils. FEBS Lett. 579, 6159–6168 (2005).
  CAS PubMed Google Scholar
• Lee, S.J. et al. Mannose receptor-mediated regulation of serum glycoprotein homeostasis. Science 295, 1898–1901 (2002).
  CAS PubMed Google Scholar
• Oka, K. et al. Lectin-like oxidized low-density lipoprotein receptor 1 mediates phagocytosis of aged/apoptotic cells in endothelial cells. Proc. Natl. Acad. Sci. USA 95, 9535–9540 (1998).
  CAS PubMed PubMed Central Google Scholar
• Yuita, H. et al. Retardation of removal of radiation-induced apoptotic cells in developing neural tubes in macrophage galactose-type C-type lectin-1-deficient mouse embryos. Glycobiology 15, 1368–1375 (2005).
  CAS PubMed Google Scholar
• Delneste, Y. et al. Involvement of LOX-1 in dendritic cell-mediated antigen cross-presentation. Immunity 17, 353–362 (2002).
  CAS PubMed Google Scholar
• van Gisbergen, K.P., Aarnoudse, C.A., Meijer, G.A., Geijtenbeek, T.B. & van Kooyk, Y. Dendritic cells recognize tumor-specific glycosylation of carcinoembryonic antigen on colorectal cancer cells through dendritic cell-specific intercellular adhesion molecule-3-grabbing nonintegrin. Cancer Res. 65, 5935–5944 (2005).
  CAS PubMed Google Scholar
• van Vliet, S.J. et al. Carbohydrate profiling reveals a distinctive role for the C-type lectin MGL in the recognition of helminth parasites and tumor antigens by dendritic cells. Int. Immunol. 17, 661–669 (2005).
  CAS PubMed Google Scholar
• Yoshida, T. et al. SRCL/CL-P1 recognizes GalNAc and a carcinoma-associated antigen, Tn antigen. J. Biochem. 133, 271–277 (2003).
  CAS PubMed Google Scholar
• Aarnoudse, C.A., Garcia Vallejo, J.J., Saeland, E. & van Kooyk, Y. Recognition of tumor glycans by antigen-presenting cells. Curr. Opin. Immunol. 18, 105–111 (2006).
  CAS PubMed Google Scholar
• van Vliet, S.J., Gringhuis, S.I., Geijtenbeek, T.B. & van Kooyk, Y. Regulation of effector T cells by antigen-presenting cells via interaction of the C-type lectin MGL with CD45. Nat. Immunol. 7, 1200–1208 (2006).
  CAS PubMed Google Scholar
• Ryan, E.J. et al. Dendritic cell-associated lectin-1: a novel dendritic cell-associated, C-type lectin-like molecule enhances T cell secretion of IL-4. J. Immunol. 169, 5638–5648 (2002).
  CAS PubMed Google Scholar
• Aragane, Y. et al. Involvement of dectin-2 in ultraviolet radiation-induced tolerance. J. Immunol. 171, 3801–3807 (2003).
  CAS PubMed Google Scholar
• Chieppa, M. et al. Cross-linking of the mannose receptor on monocyte-derived dendritic cells activates an anti-inflammatory immunosuppressive program. J. Immunol. 171, 4552–4560 (2003).
  CAS PubMed Google Scholar
• Howard, M.J. & Isacke, C.M. The C-type lectin receptor Endo180 displays internalization and recycling properties distinct from other members of the mannose receptor family. J. Biol. Chem. 277, 32320–32331 (2002).
  CAS PubMed Google Scholar
• Bonifaz, L. et al. Efficient targeting of protein antigen to the dendritic cell receptor DEC-205 in the steady state leads to antigen presentation on major histocompatibility complex class I products and peripheral CD8+ T cell tolerance. J. Exp. Med. 196, 1627–1638 (2002).
  CAS PubMed PubMed Central Google Scholar
• van Kooyk, Y. & Geijtenbeek, T.B. DC-SIGN: escape mechanism for pathogens. Nat. Rev. Immunol. 3, 697–709 (2003).
  CAS PubMed Google Scholar
• Kang, Y.S. et al. SIGN-R1, a novel C-type lectin expressed by marginal zone macrophages in spleen, mediates uptake of the polysaccharide dextran. Int. Immunol. 15, 177–186 (2003).
  CAS PubMed Google Scholar
• Arce, I., Martinez-Munoz, L., Roda-Navarro, P. & Fernandez-Ruiz, E. The human C-type lectin CLECSF8 is a novel monocyte/macrophage endocytic receptor. Eur. J. Immunol. 34, 210–220 (2004).
  CAS PubMed Google Scholar
• Mc Dermott, R. et al. Birbeck granules are subdomains of endosomal recycling compartment in human epidermal Langerhans cells, which form where Langerin accumulates. Mol. Biol. Cell 13, 317–335 (2002).
  CAS PubMed PubMed Central Google Scholar
• Sato, K. et al. Redistributions of macrophages expressing the macrophage galactose-type C-type lectin (MGL) during antigen-induced chronic granulation tissue formation. Int. Immunol. 17, 559–568 (2005).
  CAS PubMed Google Scholar
• Allavena, P., Chieppa, M., Monti, P. & Piemonti, L. From pattern recognition receptor to regulator of homeostasis: the double-faced macrophage mannose receptor. Crit. Rev. Immunol. 24, 179–192 (2004).
  CAS PubMed Google Scholar
• Koppel, E.A., van Gisbergen, K.P., Geijtenbeek, T.B. & van Kooyk, Y. Distinct functions of DC-SIGN and its homologues L-SIGN (DC-SIGNR) and mSIGNR1 in pathogen recognition and immune regulation. Cell. Microbiol. 7, 157–165 (2005).
  CAS PubMed Google Scholar
• Koppel, E.A. et al. Specific ICAM-3 grabbing nonintegrin-related 1 (SIGNR1) expressed by marginal zone macrophages is essential for defense against pulmonary Streptococcus pneumoniae infection. Eur. J. Immunol. 35, 2962–2969 (2005).
  CAS PubMed Google Scholar
• Nagaoka, K. et al. Association of SIGNR1 with TLR4-MD-2 enhances signal transduction by recognition of LPS in gram-negative bacteria. Int. Immunol. 17, 827–836 (2005).
  CAS PubMed Google Scholar
• Kang, Y.S. et al. The C-type lectin SIGN-R1 mediates uptake of the capsular polysaccharide of Streptococcus pneumoniae in the marginal zone of mouse spleen. Proc. Natl. Acad. Sci. USA 101, 215–220 (2004).
  CAS PubMed Google Scholar
• McGreal, E.P. et al. The carbohydrate-recognition domain of Dectin-2 is a C-type lectin with specificity for high mannose. Glycobiology 16, 422–430 (2006).
  CAS PubMed Google Scholar
• Stambach, N.S. & Taylor, M.E. Characterization of carbohydrate recognition by langerin, a C-type lectin of Langerhans cells. Glycobiology 13, 401–410 (2003).
  CAS PubMed Google Scholar
• Tada, Y. et al. Identification and characterization of endogenous Langerin ligands in murine extracellular matrix. J. Invest. Dermatol. 126, 1549–1558 (2006).
  CAS PubMed Google Scholar
• Turville, S., Wilkinson, J., Cameron, P., Dable, J. & Cunningham, A.L. The role of dendritic cell C-type lectin receptors in HIV pathogenesis. J. Leukoc. Biol. 74, 710–718 (2003).
  CAS PubMed Google Scholar
• Kumamoto, Y. et al. Identification of sialoadhesin as a dominant lymph node counter-receptor for mouse macrophage galactose-type C-type lectin 1. J. Biol. Chem. 279, 49274–49280 (2004).
  CAS PubMed Google Scholar
• Takada, A. et al. Human macrophage C-type lectin specific for galactose and N-acetylgalactosamine promotes filovirus entry. J. Virol. 78, 2943–2947 (2004).
  CAS PubMed PubMed Central Google Scholar
• Tsuiji, M. et al. Molecular cloning and characterization of a novel mouse macrophage C-type lectin, mMGL2, which has a distinct carbohydrate specificity from mMGL1. J. Biol. Chem. 277, 28892–28901 (2002).
  CAS PubMed Google Scholar
• Palma, A.S. et al. Ligands for the β-glucan receptor, Dectin-1, assigned using “designer” microarrays of oligosaccharide probes (neoglycolipids) generated from glucan polysaccharides. J. Biol. Chem. 281, 5771–5779 (2006)
  CAS PubMed Google Scholar