Cell-surface protein-protein interaction analysis with time-resolved FRET and snap-tag technologies: application to GPCR oligomerization (original) (raw)
Bockaert, J. & Pin, J.P. Molecular tinkering of G protein-coupled receptors: an evolutionary success. EMBO J.18, 1723–1729 (1999). ArticleCAS Google Scholar
Bayburt, T.H., Leitz, A.J., Xie, G., Oprian, D.D. & Sligar, S.G. Transducin activation by nanoscale lipid bilayers containing one and two rhodopsins. J. Biol. Chem.282, 14875–14881 (2007). ArticleCAS Google Scholar
Chabre, M. & le Maire, M. Monomeric G-protein-coupled receptor as a functional unit. Biochemistry44, 9395–9403 (2005). ArticleCAS Google Scholar
Ernst, O.P., Gramse, V., Kolbe, M., Hofmann, K.P. & Heck, M. Monomeric G protein-coupled receptor rhodopsin in solution activates its G protein transducin at the diffusion limit. Proc. Natl. Acad. Sci. USA104, 10859–10864 (2007). ArticleCAS Google Scholar
Whorton, M.R. et al. A monomeric G protein-coupled receptor isolated in a high-density lipoprotein particle efficiently activates its G protein. Proc. Natl. Acad. Sci. USA104, 7682–7687 (2007). ArticleCAS Google Scholar
Bouvier, M. Oligomerization of G-protein-coupled transmitter receptors. Nat. Rev. Neurosci.2, 274–286 (2001). ArticleCAS Google Scholar
Milligan, G. G-protein-coupled receptor heterodimers: pharmacology, function and relevance to drug discovery. Drug Discov. Today11, 541–549 (2006). ArticleCAS Google Scholar
Salahpour, A. & Masri, B. Experimental challenge to a 'rigorous' BRET analysis of GPCR oligomerization. Nat. Methods4, 599–600 (2007). ArticleCAS Google Scholar
James, J.R., Oliveira, M.I., Carmo, A.M., Iaboni, A. & Davis, S.J. A rigorous experimental framework for detecting protein oligomerization using bioluminescence resonance energy transfer. Nat. Methods3, 1001–1006 (2006). ArticleCAS Google Scholar
Meyer, B.H. et al. FRET imaging reveals that functional neurokinin-1 receptors are monomeric and reside in membrane microdomains of live cells. Proc. Natl. Acad. Sci. USA103, 2138–2143 (2006). ArticleCAS Google Scholar
Pfleger, K.D. & Eidne, K.A. Illuminating insights into protein-protein interactions using bioluminescence resonance energy transfer (BRET). Nat. Methods3, 165–174 (2006). ArticleCAS Google Scholar
Selvin, P.R. The renaissance of fluorescence resonance energy transfer. Nat. Struct. Biol.7, 730–734 (2000). ArticleCAS Google Scholar
Bazin, H., Trinquet, E. & Mathis, G. Time resolved amplification of cryptate emission: a versatile technology to trace biomolecular interactions. J. Biotechnol.82, 233–250 (2002). CAS Google Scholar
Kniazeff, J. et al. Closed state of both binding domains of homodimeric mGlu receptors is required for full activity. Nat. Struct. Mol. Biol.11, 706–713 (2004). ArticleCAS Google Scholar
Maurel, D. et al. Cell surface detection of membrane protein interaction with homogeneous time-resolved fluorescence resonance energy transfer technology. Anal. Biochem.329, 253–262 (2004). ArticleCAS Google Scholar
McVey, M. et al. Monitoring receptor oligomerization using time-resolved fluorescence resonance energy transfer and bioluminescence resonance energy transfer. The human delta-opioid receptor displays constitutive oligomerization at the cell surface, which is not regulated by receptor occupancy. J. Biol. Chem.276, 14092–14099 (2001). ArticleCAS Google Scholar
Keppler, A., Pick, H., Arrivoli, C., Vogel, H. & Johnsson, K. Labeling of fusion proteins with synthetic fluorophores in live cells. Proc. Natl. Acad. Sci. USA101, 9955–9959 (2004). ArticleCAS Google Scholar
Keppler, A. et al. A general method for the covalent labeling of fusion proteins with small molecules in vivo. Nat. Biotechnol.21, 86–89 (2003). ArticleCAS Google Scholar
Pin, J.-P. Allosteric functioning of dimeric Class C G-protein coupled receptors. FEBS J.272, 2947–2955 (2005). ArticleCAS Google Scholar
Brock, C., Boudier, L., Maurel, D., Blahos, J. & Pin, J.P. Assembly-dependent surface targeting of the heterodimeric GABAB Receptor is controlled by COPI but not 14–3-3. Mol. Biol. Cell16, 5572–5578 (2005). ArticleCAS Google Scholar
Margeta-Mitrovic, M., Jan, Y.N. & Jan, L.Y. A trafficking checkpoint controls GABA(B) receptor heterodimerization. Neuron27, 97–106 (2000). ArticleCAS Google Scholar
Brock, C. et al. Activation of a dimeric metabotropic glutamate receptor by inter-subunit rearrangement. J. Biol. Chem.282, 33000–33008 (2007). ArticleCAS Google Scholar
Bischoff, S. et al. Spatial distribution of GABA(B)R1 receptor mRNA and binding sites in the rat brain. J. Comp. Neurol.412, 1–16 (1999). ArticleCAS Google Scholar
Kaupmann, K. et al. Expression cloning of GABA(B) receptors uncovers similarity to metabotropic glutamate receptors. Nature386, 239–246 (1997). ArticleCAS Google Scholar
Selvin, P.R. & Hearst, J.E. Luminescence energy transfer using a terbium chelate: improvements on fluorescence energy transfer. Proc. Natl. Acad. Sci. USA91, 10024–10028 (1994). ArticleCAS Google Scholar
Villemure, J.F. et al. Subcellular distribution of GABA(B) receptor homo- and hetero-dimers. Biochem. J.388, 47–55 (2005). ArticleCAS Google Scholar
Lopez-Gimenez, J.F., Canals, M., Pediani, J.D. & Milligan, G. The alpha1b-adrenoceptor exists as a higher-order oligomer: effective oligomerization is required for receptor maturation, surface delivery, and function. Mol. Pharmacol.71, 1015–1029 (2007). ArticleCAS Google Scholar
Damian, M., Martin, A., Mesnier, D., Pin, J.P. & Banères, J.L. Asymmetric conformational changes in a GPCR dimer controlled by G-proteins. EMBO J.25, 5693–5702 (2006). ArticleCAS Google Scholar
Hlavackova, V. et al. Evidence for a single heptahelical domain being turned on upon activation of a dimeric GPCR. EMBO J.24, 499–509 (2005). ArticleCAS Google Scholar
White, J.F. et al. Dimerization of the class A G protein-coupled neurotensin receptor NTS1 alters G protein interaction. Proc. Natl. Acad. Sci. USA104, 12199–12204 (2007). ArticleCAS Google Scholar