Genetic alterations in hepatocellular carcinomas: association between loss of chromosome 4q and p53 gene mutations (original) (raw)
References
Aguilar, F., Hussain, S. P. & Cerutti, P. (1993) Aflatoxin B1 induces the transversion of G-T in codon 249 of the tumor suppressor gene in human hepatocytes. Proc Natl Acad Sci USA90: 8586–8590. ArticleCAS Google Scholar
Bankfalvi, A., Navabi, H., Bier, B., Bocker, W., Jasani, B. & Schmid, K. W. (1994) Wet autoclave pretreatment for antigen retrieval in diagnostic immunohistochemistry. J Pathol174: 223–228. ArticleCAS Google Scholar
Becker, S. A., Zhou, Y-Z & Slagle, B. L. (1996) Frequent loss of chromosome 8p in hepatitis B virus-positive hepatocellular carcinomas from China. Cancer Res56: 5092–5097. CASPubMed Google Scholar
Boige, V., Laurent-Puig, P., Fouchet, P., Flejou, J. F., Monges, G., Bedossa, P., Bioulac-Sage, P., Capron, F., Schmitz, A., Olschwang, S. & Thomas, G. (1997) Concerted nonsyntenic allelic losses in hyperploid hepatocellular carcinoma as determined by a high-resolution allelotype. Cancer Res57: 1986–1990. CASPubMed Google Scholar
Bourdon, J-C, D’Errico, A., Paterlini, P., Grigioni, W., May, E. & Debuire, B. (1995) p53 protein accumulation in European hepatocellular carcinoma is not always dependent on p53 gene mutation. Gastroenterology108: 1176–1182. ArticleCAS Google Scholar
Bressac, B., Kew, M., Wands, J. & Ozturk, M. (1991) Selective G to T mutations of p53 gene in hepatocellular carcinoma from southern Africa. Nature (Lond)350: 429–431. ArticleCAS Google Scholar
Brockmoller, J., Kerb, R., Drakoulis, N., Nitz, M. & Roots, I. (1993) Genotype and phenotype of glutathione S-transferase class μ isoenzymes μ and ψ in lung cancer patients and control. Cancer Res53: 1004–1011. CASPubMed Google Scholar
Buetow, K. H., Murray, J. C., Israel, J. L., London, W. T., Smith, M., Kew, M., Blanquet, V., Brechot, C., Redeker, A. & Govindarajah, S. (1989) Loss of heterozygosity suggests tumor suppressor gene responsible for primary hepatocellular carcinoma. Proc Natl Acad Sci USA86: 8852–8856. ArticleCAS Google Scholar
Chen, H-L, Chen, Y-C & Chen, D-S (1996) Chromosome 1p aberrations are frequent in human primary hepatocellular carcinoma. Cancer Genet Cytogenet86: 102–106. ArticleCAS Google Scholar
Comstock, K. E., Sanderson, B. J. S., Claflin, G. & Henner, W. D. (1990) GST1 gene deletion determined by polymerase chain reaction. Nucleic Acids Res18: 3670 ArticleCAS Google Scholar
Coursaget, P., Depril, N., Chabaud, M., Nandi, R., Mayelo, V., LeCann, P. & Yvonnet, B. (1993) High prevalence of mutations at codon 249 of the p53 gene in hepatocellular carcinomas from Senegal. Br J Cancer67: 1395–1397. ArticleCAS Google Scholar
De Souza, A. T., Hankins, G. R., Washington, M. K., Orton, T. C. & Jirtle, R. L. (1995) M6P/IGF2R gene is mutated in human hepatocellular carcinomas with loss of heterozygosity. Nature Genet11: 447–449. ArticleCAS Google Scholar
Devilee, P., Vliet, M., Bardoel, A., Kievits, T., Kuipers-Dijkshoon, N., Pearson, P. L. & Cornelisse, C. J. (1991) Frequent somatic imbalance of marker alleles for chromosome 1 in human primary breast carcinoma. Cancer Res51: 1020–1025. CASPubMed Google Scholar
Dohner, H., Bloomfield, C. D., Frizzera, G., Frestedt, J. & Arthur, D. C. (1992) Recurring chromosome abnormalities in Hodgkin’s disease. Genes Chromosom Cancer5: 392–398. ArticleCAS Google Scholar
Dracopoli, N. C., Harnett, P., Bale, S. J., Stanger, B. Z., Tucker, M. A., Housman, D. E. & Kefford, R. F. (1989) Loss of alleles from the distal short arm of chromosome 1 occurs late in melanoma tumor progression. Proc Natl Acad Sci USA88: 4614–4618. Article Google Scholar
Dumenco, L., Oguey, D., Wu, J., Messier, N. & Fausto, N. (1995) Introduction of a murine p53 mutation corresponding to human codon 249 into a murine hepatocyte cell line results in growth advantage, but not in transformation. Hepatology22: 1279–1288. CASPubMed Google Scholar
Emi, M., Fujiwara, Y., Nakajima, T., Tsuchiya, E., Tsuda, H., Hirohashi, S., Maeda, Y., Tsuruta, K., Miyaki, M. & Nakamura, Y. (1992) Frequent loss of heterozygosity for loci on chromosome 8 p in hepatocellular carcinoma, colorectal cancer, and lung cancer. Cancer Res52: 5368–5372. CASPubMed Google Scholar
Fujimori, M., Tokino, T., Hino, O., Kitagawa, T., Imamura, T., Okamoto, E., Mitsunobu, M., Ishikawa, T., Nakagama, H., Harada, H., Yagura, M., Matsubara, K. & Nakamura, Y. (1991) Allelotype study of primary hepatocellular carcinoma. Cancer Res51: 89–93. CASPubMed Google Scholar
Gleeson, C. M., Sloan, J. M., McGuigan, J. A., Ritchie, A. J., Weber, J. L. & Russell, S. H. E. (1997) Allelotype analysis of adenocarcinoma of the gastric cardia. Br J Cancer76: 1455–1465. ArticleCAS Google Scholar
Greenblatt, M. S., Feitelson, M. A., Zhu, M., Bennett, W. P., Welsh, J. A., Borkowski, A. & Harris, C. C. (1997) Integrity of p53 in hepatitis B X antigen-positive and -negative hepatocellular carcinoma. Cancer Res57: 426–432. CASPubMed Google Scholar
Groopman, J. D., Wang, J-S & Scholl, P. (1996) Molecular biomarkers for aflatoxins: from adducts to gene mutations to human liver cancer. Can J Physiol Pharmacol74: 203–209. CASPubMed Google Scholar
Hammoud, Z. T., Kaleem, Z., Cooper, J. D., Sundaresan, S., Patterson, G. A. & Goodfellow, P. J. (1996) Alleotype analysis of esophageal adenocarcinomas: evidence for the involvement of sequence on the long arm of chromosome 4. Cancer Res56: 4499–4502. CASPubMed Google Scholar
Hampton, G. M., Larson, A. A., Baergen, R. N., Sommers, R. L., Kern, S. & Cavenee, W. K. (1996) Simultaneous assessment of loss of heterozygosity at multiple microsatellite loci using semi-automated fluorescence-based detection: subregional mapping of chromosome 4 in cervical carcinoma. Proc Natl Acad Sci USA93: 6704–6709. ArticleCAS Google Scholar
Hayashi, H., Sugio, K., Matsumata, T., Adachi, E., Takenaka, K. & Sugimachi, K. (1995) The clinical significance of p53 gene mutation in hepatocelluar carcinomas from Japan. Hepatology22: 1702–1707. CASPubMed Google Scholar
Henkler, F., Waseem, N., Golding, M. H. C., Alison, M. R. & Koshy, R. (1995) Mutant p53 but not hepatitis B virus X protein is present in hepatitis B virus related human hepatocellular carcinoma. Cancer Res55: 6084–6091. CASPubMed Google Scholar
Hsu, H-C, Peng, S-Y, Lai, P-L, Sheu, J-C, Chen, D-S, Lin, L-I, Slagle, B. L. & Butel, J. S. (1994) Allelotype and loss of heterozygosity of p53 in primary and recurrent hepatocellular carcinomas. Cancer73: 42–47. ArticleCAS Google Scholar
Hsu, I. C., Metcalf, R. A., Sun, T., Welsh, J. A., Wang, N. J. & Harris, C. C. (1991) Mutational hotspot in the p53 gene in human hepatocellular carcinomas. Nature (Lond)350: 427–428. ArticleCAS Google Scholar
Hsu, I. C., Tokiwa, T., Bennett, W., Metcalf, R. A., Welsh, J. A., Sun, T. & Harris, C. C. (1993) p53 gene mutation and integrated hepatitis B viral DNA sequences in human cancer cell lines. Carcinogenesis (Lond)14: 987–992. ArticleCAS Google Scholar
Inazawa, J., Ariyama, T., Abe, T., Druck, T., Ohta, M., Huebner, K., Yanagisawa, J., Reed, J. C. & Sato, T. (1996) PTPN13, a Fas-associated protein tyrosine phosphatase, is located on the long arm of chromosome 4 at band q21.3. Genomics31: 240–242. ArticleCAS Google Scholar
Katagiri, T., Nakamura, Y. & Miki, Y. (1996) Mutations in the BRCA2 gene in hepatocellular carcinomas. Cancer Res56: 4575–4577. CASPubMed Google Scholar
Kubicka, S., Trautwein, C., Schrem, H., Tillmann, H. & Manns, M. (1995) Low incidence of p53 mutations in European hepatocellular carcinoma with heterogeneous mutation as a rare event. J Hepatol23: 412–419. ArticleCAS Google Scholar
Kuroki, T., Fujiwara, Y., Nakamori, S., Imaoka, S., Kanematsu, T. & Nakamura, Y. (1995a) Evidence for the presence of two tumour-suppressor genes for hepatocellular carcinoma on chromosome 13 q. Br J Cancer72: 383–385. ArticleCAS Google Scholar
Kuroki, T., Fujiwara, Y., Tsuchiya, E., Nakamori, S., Imaoka, S., Kanematsu, T. & Nakamura, Y. (1995b) Accumulation of genetic changes during development and progression of hepatocellular carcinoma: loss of heterozygosity on chromosome arm 1p occurs at an early stage of hepatocarcinogenesis. Genes Chromosom Cancer13: 163–167. ArticleCAS Google Scholar
Leister, I., Weith, A., Bruderlein, S., Cziepluch, C., Kangwanpong, D., Schlag, P. & Schwab, M. (1990) Human colorectal cancer: high frequency of deletions at chromosome 1p35. Cancer Res50: 7232–7235. CASPubMed Google Scholar
Leon, M. & Kew, M. C. (1996) Loss of heterozygosity in chromosome 4q12–q13 in hepatocellular carcinoma in Southern African blacks. Anticancer Res16: 349–352. CASPubMed Google Scholar
Mace, K., Aguilar, F., Wang, J-S, Vautravers, P., Gomez-Lechon, M., Gonzalez, F. J., Groopman, J., Harris, C. C. & Pfeifer, A. M. A. (1991) Aflatoxin B1-induced DNA adduct formation and p53 mutations in CYP450-expressing human liver cell lines. Carcinogenesis (Lond)7: 1291–1297. Google Scholar
Marchio, A., Meddeb, M., Pineau, P., Danglot, G., Tiollais, P., Bernheim, A. & Dejean, A. (1997) Recurrent chromosomal abnormalities in hepatocellular carcinoma detected by comparative genomic hybridization. Genes Chromosom Cancer18: 59–65. ArticleCAS Google Scholar
McGlynn, K. A., Rosvold, E. A., Lustbader, E. D., Hu, Y., Clapper, M. L., Zhou, T., Wild, C. P., Xia, X-L, Baffoe-Bonnie, A., Ofori-Adjei, D., Chen, G-C, London, W. T., Shen, F-M & Buetow, K. H. (1995) Susceptibility to hepatocellular carcinoma is associated with genetic variation in the enzymatic detoxification of aflatoxin B1 . Proc Natl Acad Sci USA92: 2384–2387. ArticleCAS Google Scholar
Mitra, A. B., Murty, VVVS, Li, R. G., Pratap, M., Luthra, U. K. & Chaganti, R. S. K. (1994) Allelotype analysis of cervical carcinoma. Cancer Res54: 4481–4487. CASPubMed Google Scholar
Nagai, H., Pineau, P., Tiollais, P., Buendia, M. A. & Dejean, A. (1997) Comprehensive allelotyping of human hepatocellular carcinoma. Oncogene14: 2927–2933. ArticleCAS Google Scholar
Nasarek, A., Werner, M., Nolte, M., Klempnauer, J. & Georgii, A. (1995) Trisomy 1 and 8 occur frequently in hepatocellular carcinoma but not in liver cell adenoma and focal nodular hyperplasia. A fluorescence in situ hybridization study. Virchows Arch427: 373–378. ArticleCAS Google Scholar
Nasir, J., Theilmann, J. L., Chopra, V., Jones, A. M., Walker, D., Rasper, D. M., Vaillancourt, J. P., Hewitt, J. E., Nicholson, D. W. & Hayden, M. R. (1997) Localization of the cell death genes CPP32 and Mch-2 to human chromosome 4q. Mammalian Genome8: 56–59. ArticleCAS Google Scholar
Ning, Y., Weber, J. L., Killary, A. M., Ledbetter, D. H., Smith, J. R. & Pereira-Smith, O. M. (1991) Genetic analysis of indefinite division in human cells: evidence for a cell senescence-related gene(s) on human chromosome 4. Proc Natl Acad Sci USA88: 5635–5639. ArticleCAS Google Scholar
Nose, H., Imazeki, F., Ohto, M. & Omata, M. (1993) p53 gene mutations and 17p allelic deletions in hepatocellular carcinoma from Japan. Cancer72: 355–360. ArticleCAS Google Scholar
Ozturk, M., Bressac, B., Puisieux, A., Kew, M., Volkmann, M., Bozcall, S., Bella Mura, J., de la Monte, S., Carlson, R., Blum, H., Wands, J., Takahashi, H., von Weizsäcker, F., Galun, E., Siddhartha, K., Carr, B. I., Schröder, C. H., Erken, E., Varinli, S., Rustgi, V. K., Prat, J., Toda, G., Koch, H. K., Liang, X. H., Tang, Z-Y, Shouval, D., Lee, H-S, Vyas, G. N. & Sarosi, I. (1991). p53 mutation in hepatocellular carcinoma after aflatoxin exposure. Lancet 338: 1356–1359
Pershouse, M. A., El-Naggar, A. K., Hurr, K., Lin, H., Yung, W. K. A. & Steck, P. A. (1997) Deletion mapping of chromosome 4 in head and neck squamous cell carcinoma. Oncogene14: 369–373. ArticleCAS Google Scholar
Polascik, T. J., Cairns, P., Chang, W. Y. H., Schoenberg, M. P. & Sidransky, D. (1995) Distinct regions of allelic loss on chromosome 4 in human primary bladder carcinoma. Cancer Res55: 5396–5399. CASPubMed Google Scholar
Ponchel, F., Puisieux, A., Tabone, E., Michot, J. P., Froschl, G., Morel, A. P., Frebourg, T., Fontaniere, B., Oberhammer, F. & Ozturk, M. (1994) Hepatocarcinoma-specific mutant p53-249ser induces mitotic activity but has no effect on transforming growth factor β1-mediated apoptosis. Cancer Res54: 2064–2068. CASPubMed Google Scholar
Qian, G-S, Ross, R. K., Yu, M. C., Yuan, J-M, Gao, Y-T, Henderson, B. E., Wogan, G. N. & Groopman, J. D. (1994) A follow-up study of urinary markers of aflatoxin exposure and liver cancer risk in Shanghai, People’s Republic of China. Cancer Epidemiol Biomarkers Prev3: 3–10. CASPubMed Google Scholar
Rashid, A. & Hamilton, S. R. (1997) Genetic alterations in sporadic and Crohn’s-associated adenocarcinomas of the small intestine. Gastroenterology113: 127–135. ArticleCAS Google Scholar
Redston, M. S., Caldas, C., Seymour, A. B., Hruban, R. H., da Costa, L., Yeo, C. J. & Kern, S. E. (1994) p53 mutations in pancreatic carcinoma and evidence of common involvement of homocopolymer tracts in DNA microdeletions. Cancer Res54: 3025–3033. CASPubMed Google Scholar
Shi, C. Y., Phang, T. W., Lin, Y., Wee, A., Li, B., Lee, H. P. & Ong, C. N. (1995) Codon 249 mutation of the p53 gene is a rare event in hepatocellular carcinomas from ethnic Chinese in Singapore. Br J Cancer72: 146–149. ArticleCAS Google Scholar
Simon, D., Knowles, B. B. & Weith, A. (1991) Abnormalities of chromosome 1 and loss of heterozygosity on 1p in primary hepatomas. Oncogene6: 765–770. CASPubMed Google Scholar
Slagle, B. L., Zhou, Y-Z, Birchmeier, W. & Scorsone, K. A. (1993) Deletion of the E-cadherin gene in hepatitis B virus-positive Chinese hepatocellular carcinomas. Hepatology18: 757–762. ArticleCAS Google Scholar
Takahashi, K., Kudo, J., Ishibashi, H., Hirata, Y. & Niho, Y. (1993) Frequent loss of heterozygosity on chromosome 22 in hepatocellular carcinoma. Hepatology17: 794–799. ArticleCAS Google Scholar
Tsuda, H., Zhang, W., Shimosato, Y., Yokota, J., Terada, M., Sugimura, T., Miyamura, T. & Hirohashi, S. (1990) Allele loss on chromosome 16 associated with progression of human hepatocellular carcinoma. Proc Natl Acad Sci USA87: 6791–6794. ArticleCAS Google Scholar
Ueda, H., Ullrich, S. J., Gangemi, J. D., Kappel, C. A., Ngo, L., Feitelson, M. A. & Jay, G. (1995) Functional inactivation but not structural mutation of p53 causes liver cancer. Nature Genet9: 41–47. ArticleCAS Google Scholar
Urano, Y., Watanabe, K., Lin, C. C., Hino, O. & Tamaoki, T. (1991) Interstitial chromosomal deletion within 4q11–q13 in a human hepatoma cell line. Cancer Res51: 1460–1464. CASPubMed Google Scholar
Verhaegh, GWCT, Jongmans, W., Jaspers, N. G. J., Natarajan, A. T., Oshimura, M., Lohman, P. H. M. & Zdzienicka, M. Z. (1995) A gene that regulates DNA replication in response to DNA damage is located on human chromosome 4q. Am J Hum Genet57: 1095–1103. CASPubMedPubMed Central Google Scholar
Walker, G. J., Hayward, N. K., Falvey, S. & Cooksley, W. G. E. (1991) Loss of somatic heterozygosity in hepatocellular carcinoma. Cancer Res51: 4367–4370. CASPubMed Google Scholar
Wang, H. P. & Rogler, C. E. (1988) Deletions in human chromosome arms 11p and 13q in primary hepatocellular carcinomas. Cytogenet Cell Genet48: 72–78. ArticleCAS Google Scholar
Weith, A., Martinsson, T., Cziepluch, C., Bruderlein, S., Amler, L. C., Berthold, F. & Schwab, M. (1989) Neuroblastoma consensus deletion maps to 1p36.1-2. Genes Chromosom Cancer1: 159–166. ArticleCAS Google Scholar
Yeh, S-H, Chen, P-J, Chen, H-L, Lai, M-Y, Wang, C-C & Chen, D-S (1994) Frequent genetic alterations at the distal region of chromosome 1p in human hepatocellular carcinomas. Cancer Res54: 4188–4192. CASPubMed Google Scholar
Yeh, S-H, Chen, P-J, Lai, M-Y & Chen, D-S (1996) Allelic loss on chromosomes 4q and 16q in hepatocellular carcinoma: association with elevated α-fetoprotein production. Gastroenterology110: 184–192. ArticleCAS Google Scholar
Yu, M-W & Chen, C-J (1994) Hepatitis B and C viruses in the development of hepatocellular carcinoma. Crit Rev Oncol Hematol17: 71–91. ArticleCAS Google Scholar
Yumoto, Y., Hanafusa, T., Hada, H., Morita, T., Ooguchi, S., Shinji, N., Mitani, T., Hamaya, K., Koide, N. & Tsuji, T. (1995) Loss of heterozygosity and analysis of mutation of p53 in hepatocellular carcinoma. J Gastroenterol Hepatol10: 179–185. ArticleCAS Google Scholar
Zhang, W., Hirohashi, S., Tsuda, H., Shimosato, Y., Yokota, J., Terada, M. & Sugimura, T. (1990) Frequent loss of heterozygosity on chromosomes 16 and 4 in human hepatocellular carcinoma. Jpn J Cancer Res81: 108–111. ArticleCAS Google Scholar
Zhang, X., Xu, H-J, Murakami, Y., Sachse, R., Yashima, K., Hirohashi, S., Hu, S-X, Benedict, W. F. & Sekiya, T. (1994) Deletions of chromosome 13q, mutations in retinoblastoma 1, and retinoblastoma protein state in human hepatocellular carcinoma. Cancer Res54: 4177–4182. CASPubMed Google Scholar