Linkage and association studies in African- and Caucasian-American populations demonstrate that SHC3 is a novel susceptibility locus for nicotine dependence (original) (raw)
Sullivan PF, Kendler KS . The genetic epidemiology of smoking. Nicotine Tob Res 1999; 1 (Suppl 2): S51–S57; discussion S69–S70. Article Google Scholar
Li MD, Cheng R, Ma JZ, Swan GE . A meta-analysis of estimated genetic and environmental effects on smoking behavior in male and female adult twins. Addiction 2003; 98: 23–31. Article Google Scholar
Li MD, Ma JZ, Cheng R, Dupont R, Williams KC, Payne TJ et al. A genome-wide scan to identify loci for smoking rate in the Framingham Heart Study populations. BMC Genet 2003; 4 (Suppl I): S103. Article Google Scholar
Bergen AW, Korczak JF, Weissbecker KA, Goldstein AM . A genome-wide search for loci contributing to smoking and alcoholism. Genet Epidemiol 1999; 17 (Suppl 1): S55–S60. Article Google Scholar
Bierut LJ, Rice JP, Goate A, Hinrichs AL, Saccone NL, Foroud T et al. A genomic scan for habitual smoking in families of alcoholics: common and specific genetic factors in substance dependence. Am J Med Genet 2004; 124A: 19–27. Article Google Scholar
Gelernter J, Liu X, Hesselbrock V, Page GP, Goddard A, Zhang H . Results of a genomewide linkage scan: support for chromosomes 9 and 11 loci increasing risk for cigarette smoking. Am J Med Genet 2004; 128B: 94–101. Article Google Scholar
Beuten J, Ma JZ, Payne TJ, Dupont RT, Crews KM, Somes G et al. Single- and multilocus allelic variants within the GABAB receptor subunit 2 (GABAB2) gene are significantly associated with nicotine dependence. Am J Hum Genet 2005; 76: 859–864. ArticleCAS Google Scholar
Beuten J, Ma JZ, Payne TJ, Dupont RT, Lou XY, Crews KM et al. Association of specific haplotyes of neurotropic tyrosine kinase receptor 2 (NTRK2) gene with vulnerability to nicotine dependence in African-Americans and European-Americans. Biol Psychiatry (Advance online publication, 19 May 2006; doi:1016/j.biopsych.2006.02.023).
Yamaguchi F, Yamaguchi K, Tokuda M, Brenner S . Molecular cloning of EDG-3 and N-Shc genes from the puffer fish, Fugu rubripes, and conservation of synteny with the human genome. FEBS Lett 1999; 459: 105–110. ArticleCAS Google Scholar
Pelicci G, Lanfrancone L, Grignani F, McGlade J, Cavallo F, Forni G et al. A novel transforming protein (SHC) with an SH2 domain is implicated in mitogenic signal transduction. Cell 1992; 70: 93–104. ArticleCAS Google Scholar
Pelicci G, Dente L, De Giuseppe A, Verducci-Galletti B, Giuli S, Mele S et al. A family of Shc related proteins with conserved PTB, CH1 and SH2 regions. Oncogene 1996; 13: 633–641. CASPubMed Google Scholar
O'Bryan JP, Songyang Z, Cantley L, Der CJ, Pawson T . A mammalian adaptor protein with conserved Src homology 2 and phosphotyrosine-binding domains is related to Shc and is specifically expressed in the brain. Proc Natl Acad Sci USA 1996; 93: 2729–2734. ArticleCAS Google Scholar
Cattaneo E, Pelicci PG . Emerging roles for SH2/PTB-containing Shc adaptor proteins in the developing mammalian brain. Trends Neurosci 1998; 21: 476–481. ArticleCAS Google Scholar
Conti L, Sipione S, Magrassi L, Bonfanti L, Rigamonti D, Pettirossi V et al. Shc signaling in differentiating neural progenitor cells. Nat Neurosci 2001; 4: 579–586. ArticleCAS Google Scholar
Nakamura T, Muraoka S, Sanokawa R, Mori N . N-Shc and Sck, two neuronally expressed Shc adapter homologs. Their differential regional expression in the brain and roles in neurotrophin and Src signaling. J Biol Chem 1998; 273: 6960–6967. ArticleCAS Google Scholar
Liu HY, Meakin SO . ShcB and ShcC activation by the Trk family of receptor tyrosine kinases. J Biol Chem 2002; 277: 26046–26056. ArticleCAS Google Scholar
Nestler EJ . Molecular neurobiology of addiction. Am J Addict 2001; 10: 201–217. ArticleCAS Google Scholar
Brunzell DH, Russell DS, Picciotto MR . In vivo nicotine treatment regulates mesocorticolimbic CREB and ERK signaling in C57Bl/6J mice. J Neurochem 2003; 84: 1431–1441. ArticleCAS Google Scholar
Thomas GM, Huganir RL . MAPK cascade signalling and synaptic plasticity. Nat Rev Neurosci 2004; 5: 173–183. ArticleCAS Google Scholar
Valjent E, Pages C, Herve D, Girault JA, Caboche J . Addictive and non-addictive drugs induce distinct and specific patterns of ERK activation in mouse brain. Eur J Neurosci 2004; 19: 1826–1836. Article Google Scholar
Miyamoto Y, Chen L, Sato M, Sokabe M, Nabeshima T, Pawson T et al. Hippocampal synaptic modulation by the phosphotyrosine adapter protein ShcC/N-Shc via interaction with the NMDA receptor. J Neurosci 2005; 25: 1826–1835. ArticleCAS Google Scholar
Troglio F, Echart C, Gobbi A, Pawson T, Pelicci PG, De Simoni MG et al. The Rai (Shc C) adaptor protein regulates the neuronal stress response and protects against cerebral ischemia. Proc Natl Acad Sci USA 2004; 101: 15476–15481. ArticleCAS Google Scholar
Heatherton TF, Kozlowski LT, Frecker RC, Fagerstrom KO . The Fagerstrom test for nicotine dependence: a revision of the Fagerstrom Tolerance Questionnaire. Br J Addict 1991; 86: 1119–1127. ArticleCAS Google Scholar
O'Connell JR, Weeks DE . PedCheck: a program for identification of genotype incompatibilities in linkage analysis. Am J Hum Genet 1998; 63: 259–266. ArticleCAS Google Scholar
Boehnke M, Cox NJ . Accurate inference of relationships in sib-pair linkage studies. Am J Hum Genet 1997; 61: 423–429. ArticleCAS Google Scholar
Shete S, Jacobs KB, Elston RC . Adding further power to the Haseman and Elston method for detecting linkage in larger sibships: weighting sums and differences. Hum Hered 2003; 55: 79–85. Article Google Scholar
Iyengar SK, Song D, Klein BE, Klein R, Schick JH, Humphrey J et al. Dissection of genomewide-scan data in extended families reveals a major locus and oligogenic susceptibility for age-related macular degeneration. Am J Hum Genet 2004; 74: 20–39. ArticleCAS Google Scholar
Barrett JC, Fry B, Maller J, Daly MJ . Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics 2005; 21: 263–265. ArticleCAS Google Scholar
Gabriel SB, Schaffner SF, Nguyen H, Moore JM, Roy J, Blumenstiel B et al. The structure of haplotype blocks in the human genome. Science 2002; 296: 2225–2229. ArticleCAS Google Scholar
Lange C, Silverman EK, Xu X, Weiss ST, Laird NM . A multivariate family-based association test using generalized estimating equations: FBAT-GEE. Biostatistics 2003; 4: 195–206. Article Google Scholar
Horvath S, Xu X, Lake SL, Silverman EK, Weiss ST, Laird NM . Family-based tests for associating haplotypes with general phenotype data: application to asthma genetics. Genet Epidemiol 2004; 26: 61–69. Article Google Scholar
Nyholt DR . A simple correction for multiple testing for single-nucleotide polymorphisms in linkage disequilibrium with each other. Am J Hum Genet 2004; 74: 765–769. ArticleCAS Google Scholar
Paxinos G, watson C . The Rat Brain in Stereotaxic Coordinates. Academic Press: Sydney, 1986. Google Scholar
Winer J, Jung CK, Shackel I, Williams PM . Development and validation of real-time quantitative reverse transcriptase-polymerase chain reaction for monitoring gene expression in cardiac myocytes in vitro. Anal Biochem 1999; 270: 41–49. ArticleCAS Google Scholar
Nyholt DR . All LODs are not created equal. Am J Hum Genet 2000; 67: 282–288. ArticleCAS Google Scholar
Sun D, Huang W, Hwang YY, Zhang Y, Zhang Q, Li MD . Regulation by nicotine of Gpr51 and Ntrk2 expression in various rat brain regions. Neuropharmacology (Advance online publication, 21 June 2006; doi:10.1038/sj.npp.1301134).
Pelicci G, Troglio F, Bodini A, Melillo RM, Pettirossi V, Coda L et al. The neuron-specific Rai (ShcC) adaptor protein inhibits apoptosis by coupling Ret to the phosphatidylinositol 3-kinase/Akt signaling pathway. Mol Cell Biol 2002; 22: 7351–7363. ArticleCAS Google Scholar
Wall JD, Pritchard JK . Haplotype blocks and linkage disequilibrium in the human genome. Nat Rev Genet 2003; 4: 587–597. ArticleCAS Google Scholar
Perez-Stable EJ, Herrera B, Jacob III P, Benowitz NL . Nicotine metabolism and intake in black and white smokers. JAMA 1998; 280: 152–156. ArticleCAS Google Scholar
Benowitz NL, Perez-Stable EJ, Fong I, Modin G, Herrera B, Jacob III P . Ethnic differences in _N_-glucuronidation of nicotine and cotinine. J Pharmacol Exp Ther 1999; 291: 1196–1203. CASPubMed Google Scholar
Batra V, Patkar AA, Berrettini WH, Weinstein SP, Leone FT . The genetic determinants of smoking. Chest 2003; 123: 1730–1739. ArticleCAS Google Scholar
Noble EP . D2 dopamine receptor gene in psychiatric and neurologic disorders and its phenotypes. Am J Med Genet 2003; 116B: 103–125. Article Google Scholar
Lu L, Hope BT, Dempsey J, Liu SY, Bossert JM, Shaham Y . Central amygdala ERK signaling pathway is critical to incubation of cocaine craving. Nat Neurosci 2005; 8: 212–219. ArticleCAS Google Scholar
Tang K, Wu H, Mahata SK, O'Connor DT . A crucial role for the mitogen-activated protein kinase pathway in nicotinic cholinergic signaling to secretory protein transcription in pheochromocytoma cells. Mol Pharmacol 1998; 54: 59–69. ArticleCAS Google Scholar
Mazzucchelli C, Vantaggiato C, Ciamei A, Fasano S, Pakhotin P, Krezel W et al. Knockout of ERK1 MAP kinase enhances synaptic plasticity in the striatum and facilitates striatal-mediated learning and memory. Neuron 2002; 34: 807–820. ArticleCAS Google Scholar
Sanna PP, Simpson C, Lutjens R, Koob G . ERK regulation in chronic ethanol exposure and withdrawal. Brain Res 2002; 948: 186–191. ArticleCAS Google Scholar
Konu O, Kane JK, Barrett T, Vawter MP, Chang R, Ma JZ et al. Region-specific transcriptional response to chronic nicotine in rat brain. Brain Res 2001; 909: 194–203. ArticleCAS Google Scholar
Chen J, Sidhu A . The role of D1 dopamine receptors and phospho-ERK in mediating cytotoxicity (Commentary). Neurotox Res 2005; 7: 179–181. Article Google Scholar
Wang C, Buck DC, Yang R, Macey TA, Neve KA . Dopamine D2 receptor stimulation of mitogen-activated protein kinases mediated by cell type-dependent transactivation of receptor tyrosine kinases. J Neurochem 2005; 93: 899–909. ArticleCAS Google Scholar
Breslau N, Peterson EL, Schultz LR, Chilcoat HD, Andreski P . Major depression and stages of smoking. A longitudinal investigation. Arch Gen Psychiatry 1998; 55: 161–166. ArticleCAS Google Scholar
Murphy JM, Horton NJ, Monson RR, Laird NM, Sobol AM, Leighton AH . Cigarette smoking in relation to depression: historical trends from the Stirling County Study. Am J Psychiatry 2003; 160: 1663–1669. Article Google Scholar
Kendler KS, Neale MC, MacLean CJ, Heath AC, Eaves LJ, Kessler RC . Smoking and major depression. A causal analysis. Arch Gen Psychiatry 1993; 50: 36–43. ArticleCAS Google Scholar
Dierker LC, Avenevoli S, Stolar M, Merikangas KR . Smoking and depression: an examination of mechanisms of comorbidity. Am J Psychiatry 2002; 159: 947–953. Article Google Scholar