Dendritic cells: On the move from bench to bedside (original) (raw)

• Banchereau, J. & Steinman, R.M. Dendritic cells and the control of immunity. Nature 392, 245–252 (1998).
  Article CAS Google Scholar
• Lotze, M.T., Shurin, M., Davis, I., Amoscato, A. & Storkus, W.J. Dendritic cell based therapy of cancer. Adv. Exp. Med. Biol. 417, 551–569 (1997).
  Article CAS Google Scholar
• Clark, G.J. & Hart, D.N.J. Phenotypic characterization of dendritic cells. in Dendritic Cells: Biology and Clinical Applications (ed. Lotze, M.T.) 555–557 (Academic, London, 1998).
  Google Scholar
• Gilboa, E., Nair, S.K. & Lyerly, H.K. Immunotherapy of cancer with dendritic-cell-based vaccines. Cancer Immunol. Immunother. 46, 82–87 (1998).
  Article CAS Google Scholar
• Young, J.W. & Inaba, K. Dendritic cells as adjuvants for class I major histocompatibility complex-restricted antitumor immunity. J. Exp.Med. 183, 7–11 (1996).
  Article CAS Google Scholar
• Timmerman, J.M. & Levy, R. Dendritic cell vaccines for cancer immunotherapy. Annu. Rev. Med. 50, 507–529 (1999).
  Article CAS Google Scholar
• Nestle, F.O. et al. Vaccination of melanoma patients with peptide- or tumor lysate-pulsed dendritic cells. Nature Med. 4, 328–332 (1998).
  Article CAS Google Scholar
• Thurner, B. et al. Vaccination with mage-3A1 peptide-pulsed mature, monocyte-derived dendritic cells expands specific cytotoxic T cells and induces regression of some metastases in advanced stage IV melanoma. J. Exp. Med. 190, 1669–1678 (1999).
  Article CAS Google Scholar
• Fong, L. & Engleman, E.G. Dendritic cells in cancer immunotherapy. Annu. Rev. Immunol. 18, 245–273 (2000).
  Article CAS Google Scholar
• Sallusto, F. & Lanzavecchia, A. Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony- stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor-α. J. Exp. Med. 179, 1109–1118 (1994).
  Article CAS Google Scholar
• Romani, N. et al. Proliferating dendritic cell progenitors in human blood. J. Exp. Med. 180, 83–93 (1994).
  Article CAS Google Scholar
• Randolph, G.J., Inaba, K., Robbiani, D.F., Steinman, R.M. & Muller, W.A. Differentiation of phagocytic monocytes into lymph node dendritic cells in vivo. Immunity 11, 753–7561 (1999).
  Article CAS Google Scholar
• Banchereau, J., Pulendran, B., Steinman, R. & Palucka, K. Will the making of plasmacytoid dendritic cells in vitro help unravel their mysteries? J. Exp. Med. 192 (2000).
• Hart, D.N.J. et al. 7th leucocyte differentiation antigen workshop dendritic cells section summary. in Leucocyte Typing Vol. VII (ed. Mason, D.) (Oxford University Press, Oxford, 2000).
  Google Scholar
• Schuler, G. & Steinman, R.M. Murine epidermal Langerhans cells mature into potent allostimulatory dendritic cells in vitro. J. Exp. Med. 161, 526–546 (1985).
  Article CAS Google Scholar
• Dhodapkar, M.V. et al. Rapid generation of broad T-cell immunity in humans after a single injection of mature dendritic cells. J. Clin. Invest. 104, 173–180. (1999).
  Article CAS Google Scholar
• Lodge, P.A., Jones, L.A., Bader, R.A., Murphy, G.P. & Salgaller, M.L. Dendritic cell-based immunotherapy of prostate cancer: immune monitoring of a phase II clinical trial. Cancer Res. 60, 829–833. (2000).
  CAS PubMed Google Scholar
• Murphy, G.P. et al. Infusion of dendritic cells pulsed with HLA-A2-specific prostate-specific membrane antigen peptides: A phase 2 prostate cancer vaccine trial involving patients with hormone-refractory metastatic disease. Prostate. 38, 73–78 (1999).
  Article CAS Google Scholar
• Hsu, F.J. et al. Vaccination of patients with B-cell lymphoma using autologous antigen-pulsed dendritic cells. Nature Med. 2, 52–57 (1996).
  Article CAS Google Scholar
• Dhodapkar, M.V., Steinman, R.M., Krasovsky, J., Munz, M. & Bhardwaj, N. Antigen-specific inhibition of effector T cell function in humans after injection of immature dendritic cells. J. Exp. Med. 193, 233–238 (2001).
  Article CAS Google Scholar
• Toes, R.E. et al. Enhancement of tumor outgrowth through CTL tolerization after peptide vaccination is avoided by peptide presentation on dendritic cells. J. Immunol. 160, 4449–4456 (1998).
  CAS PubMed Google Scholar
• Small, E.J. et al. Immunotherapy of hormone-refractory prostate cancer with antigen-loaded dendritic cells. J. Clin. Oncol. 18, 3894–3903 (2000).
  Article CAS Google Scholar
• Binder, R.J., Han, D.K. & Srivastava, P.K. CD91: a receptor for heat shock protein gp96. Nature Immunol. 1, 151–155 (2000).
  Article CAS Google Scholar
• Kugler, A. et al. Regression of human metastatic renal cell carcinoma after vaccination with tumor cell-dendritic cell hybrids. Nature Med. 6, 332–336 (2000).
  Article CAS Google Scholar
• Boczkowski, D., Nair, S.K., Nam, J.H., Lyerly, H.K. & Gilboa, E. Induction of tumor immunity and cytotoxic T lymphocyte responses using dendritic cells transfected with messenger RNA amplified from tumor cells. Cancer Res. 60, 1028–1034 (2000).
  CAS PubMed Google Scholar
• Vonderheide, R.H., Hahn, W.C., Schultze, J.L. & Nadler, L.M. The telomerase catalytic subunit is a widely expressed tumor-associated antigen recognized by cytotoxic T lymphocytes. Immunity 10, 673–679 (1999).
  Article CAS Google Scholar
• Dhodapkar, M.V., Krasovsky, J., Steinman, R.M. & Bhardwaj, N. Mature dendritic cells boost functionally superior CD8(+) T-cell in humans without foreign helper epitopes. J. Clin. Invest. 105, R9–R14 (2000).
  Article CAS Google Scholar
• Eggert, A. et al. Biodistribution and vaccine efficiency of murine dendritic cells are dependent on the route of administration. Cancer Res. 59, 3340–3345 (1999).
  CAS PubMed Google Scholar
• Barratt-Boyes, S.M. et al. Maturation and trafficking of monocyte-derived dendritic cells in monkeys: implications for dendritic cell-based vaccines. J. Immunol. 164, 2487–2495 (2000).
  Article CAS Google Scholar
• Thomas, R. et al. Immature human monocyte-derived dendritic cells migrate rapidly to draining lymph nodes after intradermal injection for melanoma immunotherapy. Melanoma Res. 9, 474–481 (1999).
  Article CAS Google Scholar
• Morse, M.A. et al. Migration of human dendritic cells after injection in patients with metastatic malignancies. Cancer Res. 59, 56–58 (1999).
  CAS PubMed Google Scholar
• Fong, L., Brockstedt, D., Benike, C., Wu, L. & Engleman, E.G. Dendritic cells injected via different routes induce immunity in cancer patients. J. Immunol. 166, 4254–4259. (2001).
  Article CAS Google Scholar
• Serody, J.S., Collins, E.J., Tisch, R.M., Kuhns, J.J. & Frelinger, J.A. T cell activity after dendritic cell vaccination is dependent on both the type of antigen and the mode of delivery. J Immunol. 164, 4961–4967 (2000).
  Article CAS Google Scholar
• Morse, M. et al. A phase 1 study of active immunotherapy with carcinoembryonic antigen peptide (CAP-1)-pulsed, autologous human cultured dendritic cells in patients with metastatic malignancies expressing carcinoembryonic antigen. Clin. Cancer Res. 5, 1331–1338 (1999).
  CAS PubMed Google Scholar
• Feuerstein, B. et al. A method for the production of cryopreserved aliquots of antigen- preloaded, mature dendritic cells ready for clinical use. J. Immunol. Meth. 245, 15–29 (2000).
  Article CAS Google Scholar
• Ludewig, B. et al. Immunotherapy with dendritic cells directed against tumor antigens shared with normal host cells results in severe autoimmune disease. J. Exp. Med. 191, 795–803 (2000).
  Article CAS Google Scholar
• Heiser, A. et al. Human dendritic cells transfected with renal tumor RNA stimulate polyclonal T-Cell responses against antigens expressed by primary and metastatic tumors. Cancer Res. 61, 3388–3393 (2001).
  CAS PubMed Google Scholar
• Mackensen, A., Drager, R., Schlesier, M., Mertelsmann, R. & Lindemann, A. Presence of IgE antibodies to bovine serum albumin in a patient developing anaphylaxis after vaccination with human peptide-pulsed dendritic cells. Cancer Immunol. Immunother. 49, 152–156 (2000).
  Article CAS Google Scholar
• McGuckin, M.A., MacDonald, K.P.A., Tran, M., Wykes, M. & Hart, D.N.J. MUC1 epithelial mucin—expression by normal haematopoietic cells. in Leucocyte Typing, Vol. VII (ed. Mason, D.) (Oxford University Press, Oxford, 2000).
  Google Scholar
• Romero, P., Cerottini, J.C. & Waanders, G.A. Novel methods to monitor antigen-specific cytotoxic T-cell responses in cancer immunotherapy. Mol. Med. Today 4, 305–312 (1998).
  Article CAS Google Scholar
• Kammula, U.S., Marincola, F.M. & Rosenberg, S.A. Real-time quantitative polymerase chain reaction assessment of immune reactivity in melanoma patients after tumor peptide vaccination. J. Natl. Cancer Inst. 92, 1336–1344 (2000).
  Article CAS Google Scholar
• Panelli, M.C. et al. Expansion of tumor-T cell pairs from fine needle aspirates of melanoma metastases. J. Immunol. 164, 495–504 (2000).
  Article CAS Google Scholar
• Marincola, F.M., Jaffee, E.M., Hicklin, D.J. & Ferrone, S. Escape of human solid tumors from T-cell recognition: Molecular mechanisms and functional significance. Adv. Immunol. 74, 181–273 (2000).
  Article CAS Google Scholar
• Hart, D.N.J. & Hill, G.R. Dendritic cell immunotherapy for cancer: application to low-grade lymphoma and multiple myeloma. Immunol. Cell Biol. 77, 451–459 (1999).
  Article CAS Google Scholar