Novel insight into stem cell mobilization-Plasma sphingosine-1-phosphate is a major chemoattractant that directs the egress of hematopoietic stem progenitor cells from the bone marrow and its level in peripheral blood increases during mobilization due to activation of complement cascade/membrane attack complex (original) (raw)
Lee H, Ratajczak MZ . Innate immunity: a key player in the mobilization of hematopoietic stem/progenitor cells. Arch Immunol Ther Exp (Warsz) 2009; 57: 269–278. ArticleCAS Google Scholar
Kassirer M, Zeltser D, Gluzman B, Leibovitz E, Goldberg Y, Roth A et al. The appearance of L-selectin(low) polymorphonuclear leukocytes in the circulating pool of peripheral blood during myocardial infarction correlates with neutrophilia and with the size of the infarct. Clin Cardiol 1999; 22: 721–726. ArticleCASPubMed Google Scholar
Kyne L, Hausdorff JM, Knight E, Dukas L, Azhar G, Wei JY . Neutrophilia and congestive heart failure after acute myocardial infarction. Am Heart J 2000; 139 (1 Part 1): 94–100. ArticleCASPubMed Google Scholar
Petit I, Szyper-Kravitz M, Nagler A, Lahav M, Peled A, Habler L et al. G-CSF induces stem cell mobilization by decreasing bone marrow SDF-1 and upregulating CXCR4. Nat Immunol 2002; 3: 687–694. ArticleCASPubMed Google Scholar
Sweeney EA, Lortat-Jacob H, Priestley GV, Nakamoto B, Papayannopoulou T . Sulfated polysaccharides increase plasma levels of SDF-1 in monkeys and mice: involvement in mobilization of stem/progenitor cells. Blood 2002; 99: 44–51. ArticleCASPubMed Google Scholar
Lapidot T, Dar A, Kollet O . How do stem cells find their way home? Blood 2005; 106: 1901–1910. ArticleCASPubMed Google Scholar
Peled A, Grabovsky V, Habler L, Sandbank J, Arenzana-Seisdedos F, Petit I et al. The chemokine SDF-1 stimulates integrin-mediated arrest of CD34+ cells on vascular endothelium under shear flow. J Clin Invest 1999; 104: 1199–1211. ArticleCASPubMedPubMed Central Google Scholar
Lévesque JP, Takamatsu Y, Nilsson SK, Haylock DN, Simmons PJ . Vascular cell adhesion molecule-1 (CD106) is cleaved by neutrophil proteases in the bone marrow following hematopoietic progenitor cell mobilization by granulocyte colony-stimulating factor. Blood 2001; 98: 1289–1297. ArticlePubMed Google Scholar
Lévesque JP, Hendy J, Takamatsu Y, Simmons PJ, Bendall LJ . Disruption of the CXCR4/CXCL12 chemotactic interaction during hematopoietic stem cell mobilization induced by GCSF or cyclophosphamide. J Clin Invest 2003; 111: 187–196. ArticlePubMedPubMed Central Google Scholar
Lévesque JP, Hendy J, Winkler IG, Takamatsu Y, Simmons PJ . Granulocyte colony-stimulating factor induces the release in the bone marrow of proteases that cleave c-KIT receptor (CD117) from the surface of hematopoietic progenitor cells. Exp Hematol 2003; 31: 109–117. ArticlePubMed Google Scholar
Molendijk WJ, van Oudenaren A, van Dijk H, Daha MR, Benner R . Complement split product C5a mediates the lipopolysaccharide-induced mobilization of CFU-s and haemopoietic progenitor cells, but not the mobilization induced by proteolytic enzymes. Cell Tissue Kinet 1986; 19: 407–417. CASPubMed Google Scholar
Reca R, Cramer D, Yan J, Laughlin MJ, Janowska-Wieczorek A, Ratajczak J et al. A novel role of complement in mobilization: immunodeficient mice are poor granulocyte-colony stimulating factor mobilizers because they lack complement-activating immunoglobulins. Stem Cells 2007; 25: 3093–3100. ArticleCASPubMed Google Scholar
Liu F, Poursine-Laurent J, Link DC . Expression of the G-CSF receptor on hematopoietic progenitor cells is not required for their mobilization by G-CSF. Blood 2000; 95: 3025–3031. CASPubMed Google Scholar
Pruijt JF, Verzaal P, van Os R, de Kruijf EJ, van Schie ML, Mantovani A et al. Neutrophils are indispensable for hematopoietic stem cell mobilization induced by interleukin-8 in mice. Proc Natl Acad Sci USA 2002; 99: 6228–6233. ArticleCASPubMedPubMed Central Google Scholar
Lee HM, Wu W, Wysoczynski M, Liu R, Zuba-Surma EK, Kucia M et al. Impaired mobilization of hematopoietic stem/progenitor cells in C5-deficient mice supports the pivotal involvement of innate immunity in this process and reveals novel promobilization effects of granulocytes. Leukemia 2009; 23: 2052–2062. ArticleCASPubMedPubMed Central Google Scholar
Hänel P, Andréani P, Gräler MH . Erythrocytes store and release sphingosine 1-phosphate in blood. FASEB J 2007; 21: 1202–1209. ArticlePubMed Google Scholar
Ohkawa R, Nakamura K, Okubo S, Hosogaya S, Ozaki Y, Tozuka M et al Plasma sphingosine-1-phosphate measurement in healthy subjects: close correlation with red blood cell parameters. Ann Clin Biochem 2008; 45 (Part 4): 356–363. ArticleCASPubMed Google Scholar
Lee MJ, Van Brocklyn JR, Thangada S, Liu CH, Hand AR, Menzeleev R et al. Sphingosine-1-phosphate as a ligand for the G protein-coupled receptor EDG-1. Science 1998; 279: 1552–1555. ArticleCASPubMed Google Scholar
Lee HM, Wysoczynski M, Liu R, Shin DM, Kucia M, Botto M et al. Mobilization studies in complement-deficient mice reveal that optimal AMD3100 mobilization of hematopoietic stem cells depends on complement cascade activation by AMD3100-stimulated granulocytes. Leukemia 2009; doi: 10.1038/leu.2009.271. e-pub ahead of print.
Ringstad L, Andersson Nordahl E, Schmidtchen A, Malmsten M . Composition effect on peptide interaction with lipids and bacteria: variants of C3a peptide CNY21. Biophys J 2007; 92: 87–98. ArticleCASPubMed Google Scholar
Schwab SR, Pereira JP, Matloubian M, Xu Y, Huang Y, Cyster JG . Lymphocyte sequestration through S1P lyase inhibition and disruption of S1P gradients. Science 2005; 309: 1735–1739. ArticleCASPubMed Google Scholar
Seitz G, Boehmler AM, Kanz L, Möhle R . The role of sphingosine 1-phosphate receptors in the trafficking of hematopoietic progenitor cells. Ann N Y Acad Sci 2005; 1044: 84–89. ArticleCASPubMed Google Scholar
Glaspy JA, Shpall EJ, LeMaistre CF, Briddell RA, Menchaca DM, Turner SA et al. Peripheral blood progenitor cell mobilization using stem cell factor in combination with filgrastim in breast cancer patients. Blood 1997; 90: 2939–2951. CASPubMed Google Scholar
Chabannon C, Le Corroller AG, Viret F, Eillen C, Faucher C, Moatti JP et al. Cost-effectiveness of repeated aphereses in poor mobilizers undergoing high-dose chemotherapy and autologous hematopoietic cell transplantation. Leukemia 2003; 17: 811–813. ArticleCASPubMed Google Scholar
Bellucci R, De Propris MS, Buccisano F, Lisci A, Leone G, Tabilio A et al. Modulation of VLA-4 and L-selectin expression on normal CD34+ cells during mobilization with G-CSF. Bone Marrow Transplant 1999; 23: 1–8. ArticleCASPubMed Google Scholar
Katayama Y, Battista M, Kao WM, Hidalgo A, Peired AJ, Thomas SA et al. Signals from the sympathetic nervous system regulate hematopoietic stem cell egress from bone marrow. Cell 2006; 124: 407–421. ArticleCASPubMed Google Scholar
McQuibban GA, Butler GS, Gong JH, Bendall L, Power C, Clark-Lewis I et al. Matrix metalloproteinase activity inactivates the CXC chemokine stromal cell-derived factor-1. J Biol Chem 2001; 276: 43503–43508. ArticleCASPubMed Google Scholar
Semerad CL, Christopher MJ, Liu F, Short B, Simmons PJ, Winkler I et al. G-CSF potently inhibits osteoblast activity and CXCL12 mRNA expression in the bone marrow. Blood 2005; 106: 3020–3027. ArticleCASPubMedPubMed Central Google Scholar
Kollet O, Dar A, Lapidot T . The multiple roles of osteoclasts in host defense: bone remodeling and hematopoietic stem cell mobilization. Annu Rev Immunol 2007; 25: 51–69. ArticleCASPubMed Google Scholar
Winkler IG, Levesque JP . Mechanisms of hematopoietic stem cell mobilization: when innate immunity assails the cells that make blood and bone. Exp Hematol 2006; 34: 996–1009. ArticleCASPubMed Google Scholar
van Pel M, van Os R, Velders GA, Hagoort H, Heegaard PM, Lindley IJ et al. Serpina1 is a potent inhibitor of IL-8-induced hematopoietic stem cell mobilization. Proc Natl Acad Sci USA 2006; 103: 1469–1474. ArticleCASPubMedPubMed Central Google Scholar
Pruijt JF, Fibbe WE, Laterveer L, Pieters RA, Lindley IJ, Paemen L et al. Prevention of interleukin-8-induced mobilization of hematopoietic progenitor cells in rhesus monkeys by inhibitory antibodies against the metalloproteinase gelatinase B (MMP-9). Proc Natl Acad Sci USA 1999; 96: 10863–10868. ArticleCASPubMedPubMed Central Google Scholar
King AG, Horowitz D, Dillon SB, Levin R, Farese AM, MacVittie TJ et al. Rapid mobilization of murine hematopoietic stem cells with enhanced engraftment properties and evaluation of hematopoietic progenitor cell mobilization in rhesus monkeys by a single injection of SB-251353, a specific truncated form of the human CXC chemokine GRO-beta. Blood 2001; 97: 1534–1542. ArticleCASPubMed Google Scholar
Liles WC, Broxmeyer HE, Rodger E, Wood B, Hübel K, Cooper S et al. Mobilization of hematopoietic progenitor cells in healthy volunteers by AMD3100, a CXCR4 antagonist. Blood 2003; 102: 2728–2730. ArticleCASPubMed Google Scholar
Ramirez P, Rettig MP, Uy GL, Deych E, Holt MS, Ritchey JK et al. BIO5192, a small molecule inhibitor of VLA-4, mobilizes hematopoietic stem and progenitor cells. Blood 2009; 114: 1340–1343. ArticleCASPubMedPubMed Central Google Scholar
Cramer DE, Wagner S, Li B, Liu J, Hansen R, Reca R et al. Mobilization of hematopoietic progenitor cells by yeast-derived beta-glucan requires activation of matrix metalloproteinase-9. Stem Cells 2008; 26: 1231–1240. ArticleCASPubMed Google Scholar
Hattori K, Heissig B, Tashiro K, Honjo T, Tateno M, Shieh JH et al. Plasma elevation of stromal cell-derived factor-1 induces mobilization of mature and immature hematopoietic progenitor and stem cells. Blood 2001; 97: 3354–3360. ArticleCASPubMed Google Scholar
Wright DE, Bowman EP, Wagers AJ, Butcher EC, Weissman IL . Hematopoietic stem cells are uniquely selective in their migratory response to chemokines. J Exp Med 2002; 195: 1145–1154. ArticleCASPubMedPubMed Central Google Scholar
Kozuka T, Ishimaru F, Fujii K, Masuda K, Kaneda K, Imai T et al. Plasma stromal cell-derived factor-1 during granulocyte colony-stimulating factor-induced peripheral blood stem cell mobilization. Bone Marrow Transplant 2003; 31: 651–654. ArticleCASPubMed Google Scholar
Cecyn KZ, Schimieguel DM, Kimura EY, Yamamoto M, Oliveira JS . Plasma levels of FL and SDF-1 and expression of FLT-3 and CXCR4 on CD34+ cells assessed pre and post hematopoietic stem cell mobilization in patients with hematologic malignancies and in healthy donors. Transfus Apher Sci 2009; 40: 159–167. ArticlePubMed Google Scholar
Lamming CE, Augustin L, Blackstad M, Lund TC, Hebbel RP, Verfaillie CM . Spontaneous circulation of myeloid–lymphoid-initiating cells and SCID-repopulating cells in sickle cell crisis. J Clin Invest 2003; 111: 811–819. ArticleCASPubMedPubMed Central Google Scholar
Wei SH, Rosen H, Matheu MP, Sanna MG, Wang SK, Jo E et al. Sphingosine 1-phosphate type 1 receptor agonism inhibits transendothelial migration of medullary T cells to lymphatic sinuses. Nat Immunol 2005; 6: 1228–1235. ArticleCASPubMed Google Scholar
Pappu R, Schwab SR, Cornelissen I, Pereira JP, Regard JB, Xu Y et al. Promotion of lymphocyte egress into blood and lymph by distinct sources of sphingosine-1-phosphate. Science 2007; 316: 295–298. ArticleCASPubMed Google Scholar
Sanchez T, Hla T . Structural and functional characteristics of S1P receptors. J Cell Biochem 2004; 92: 913–922. ArticleCASPubMed Google Scholar
Rivera J, Proia RL, Olivera A . The alliance of sphingosine-1-phosphate and its receptors in immunity. Nat Rev Immunol 2008; 8: 753–763. ArticleCASPubMedPubMed Central Google Scholar
Sainz J, Sata M . CXCR4, a key modulator of vascular progenitor cells. Arterioscler Thromb Vasc Biol 2007; 27: 263–265. ArticleCASPubMed Google Scholar
Bessler M, Hiken J . The pathophysiology of disease in patients with paroxysmal nocturnal hemoglobinuria. Hematology Am Soc Hematol Educ Program 2008, 104–110.
Sensken SC, Bode C, Gräler MH . Accumulation of fingolimod (FTY720) in lymphoid tissues contributes to prolonged efficacy. J Pharmacol Exp Ther 2009; 328: 963–969. ArticleCASPubMed Google Scholar
Jalili A, Shirvaikar N, Marquez-Curtis N, Qiu Y, Korol Ch, Lee H et al. Fifth complement cascade protein (C5) cleavage fragments disrupt the SDF-1/CXCR4 axis: further evidence that innate immunity orchestrates the mobilization of hematopoietic stem/progenitor cells. Exp Hematol 2010; doi: 10.1016/j.exphem.2010.02.002. e-pub ahead of print.