Singleton deletions throughout the genome increase risk of bipolar disorder (original) (raw)

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Acknowledgements

This paper was prepared as part of the bipolar collaboration of the GAIN, and was submitted before the end of the publication embargo for non-GAIN scientists. We acknowledge Dr Dan Nicolae (University of Chicago) for extensive statistical discussion and advice, Mr Xiaotong Zhang (University of Chicago) for his excellent software support and Ms Kay Grennan (University of Chicago) for her technical assistance. This work was supported by grants from 1R01MH081804-01 (NIMH), NARSAD, the Eklund family and the Geraldi Norton Foundation.

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Authors and Affiliations

1. Department of Psychiatry and Behavioral Neuroscience, The University of Chicago, Chicago, IL, USA
   D Zhang, L Cheng, Y Qian, N Alliey-Rodriguez, C Liu & E S Gershon
2. Department of Psychiatry, University of California, San Diego, La Jolla, CA, USA
   J R Kelsoe, T Greenwood, C Nievergelt, T B Barrett & R McKinney
3. Department of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, CA, USA
   N Schork, E N Smith & C Bloss
4. Scripps Genomic Medicine and Scripps Translational Science Institute, La Jolla, CA, USA
   N Schork, E N Smith & C Bloss
5. Department of Psychiatry, Indiana University School of Medicine, Indianapolis, IN, USA
   J Nurnberger & D Koller
6. Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN, USA
   H J Edenberg
7. Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN, USA
   H J Edenberg & T Foroud
8. Department of Psychiatry, Rush University, Chicago, IL, USA
   W Sheftner
9. Department of Psychiatry, Howard University, Washington, DC, USA
   W B Lawson, E A Nwulia & M Hipolito
10. Department of Psychiatry, University of Iowa, Iowa City, IA, USA
    W Coryell
11. Division of Biosiatistics, Washington University, St Louis, MO, USA
    J Rice
12. Department of Psychiatry, University of California, San Francisco, CA, USA
    W Byerley
13. US Department of Health and Human Services, Genetic Basis of Mood and Anxiety Disorders Unit, National Institute of Mental Health Intramural Research Program, National Institutes of Health, Bethesda, MD, USA
    F McMahon & T G Schulze
14. Department of Psychiatry, University of Pennsylvania, Philadelphia, PA, USA
    W Berrettini
15. Department of Psychiatry, Johns Hopkins School of Medicine, Baltimore, MD, USA
    J B Potash, P L Belmonte & P P Zandi
16. Department of Psychiatry, University of Michigan, Ann Arbor, MI, USA
    M G McInnis & S Zöllner
17. Neurogenomics Division, The Translational Genomics Research Institute, Phoenix, AZ, USA
    D Craig & S Szelinger
18. Department of Human Genetics, The University of Chicago, Chicago, IL, USA
    S L Christian & E S Gershon

Authors

1. D Zhang
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2. L Cheng
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3. Y Qian
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4. N Alliey-Rodriguez
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5. J R Kelsoe
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6. T Greenwood
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7. C Nievergelt
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8. T B Barrett
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9. R McKinney
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10. N Schork
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11. E N Smith
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12. C Bloss
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13. J Nurnberger
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14. H J Edenberg
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15. T Foroud
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16. W Sheftner
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17. W B Lawson
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18. E A Nwulia
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19. M Hipolito
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20. W Coryell
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21. J Rice
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22. W Byerley
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23. F McMahon
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24. T G Schulze
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25. W Berrettini
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26. J B Potash
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27. P L Belmonte
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28. P P Zandi
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29. M G McInnis
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30. S Zöllner
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31. D Craig
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32. S Szelinger
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33. D Koller
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34. S L Christian
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35. C Liu
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36. E S Gershon
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Corresponding authors

Correspondence toC Liu or E S Gershon.

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Supplementary Information accompanies the paper on the Molecular Psychiatry website (http://www.nature.com/mp)

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Zhang, D., Cheng, L., Qian, Y. et al. Singleton deletions throughout the genome increase risk of bipolar disorder.Mol Psychiatry 14, 376–380 (2009). https://doi.org/10.1038/mp.2008.144

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• Received: 26 November 2008
• Accepted: 02 December 2008
• Published: 30 December 2008
• Issue Date: April 2009
• DOI: https://doi.org/10.1038/mp.2008.144

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