Nonsense-mediated messenger RNA decay is initiated by endonucleolytic cleavage in Drosophila (original) (raw)
References
Wagner, E. & Lykke-Andersen, J. mRNA surveillance: the perfect persist. J. Cell Sci.115, 3033–3038 (2002) CASPubMed Google Scholar
Wilusz, C. J., Wormington, M., Stuart, W. & Peltz, S. W. The cap-to-tail guide to mRNA turnover. Nature Rev. Mol. Cell Biol.2, 237–246 (2001) ArticleCAS Google Scholar
Cao, D. & Parker, R. Computational modeling and experimental analysis of nonsense-mediated decay in yeast. Cell113, 533–545 (2003) ArticleCASPubMed Google Scholar
Chen, C. Y. & Shyu, A. B. Rapid deadenylation triggered by a nonsense codon precedes decay of the RNA body in a mammalian cytoplasmic nonsense-mediated decay pathway. Mol. Cell. Biol.23, 4805–4813 (2003) ArticleCASPubMedPubMed Central Google Scholar
Hagan, K. W., Ruiz-Echevarria, M. J., Quan, Y. & Peltz, S. W. Characterization of cis-acting sequences and decay intermediates involved in nonsense-mediated mRNA turnover. Mol. Cell. Biol.15, 809–823 (1995) ArticleCASPubMedPubMed Central Google Scholar
Lejeune, F., Li, X. & Maquat, L. E. Nonsense-mediated mRNA decay in mammalian cells involves decapping, deadenylating, and exonucleolytic activities. Mol. Cell12, 675–687 (2003) ArticleCASPubMed Google Scholar
Mitchell, P. & Tollervey, D. An NMD pathway in yeast involving accelerated deadenylation and exosome-mediated 3′ → 5′ degradation. Mol. Cell11, 1405–1413 (2003) ArticleCASPubMed Google Scholar
Muhlrad, D. & Parker, R. Premature translational termination triggers mRNA decapping. Nature370, 578–581 (1994) ArticleADSCASPubMed Google Scholar
Muhlrad, D. & Parker, R. Aberrant mRNAs with extended 3′ UTRs are substrates for rapid degradation by mRNA surveillance. RNA5, 1299–1307 (1999) ArticleCASPubMedPubMed Central Google Scholar
He, F. & Jacobson, A. Upf1p, Nmd2p, and Upf3p regulate the decapping and exonucleolytic degradation of both nonsense-containing mRNAs and wild-type mRNAs. Mol. Cell. Biol.21, 1515–1530 (2001) ArticleCASPubMedPubMed Central Google Scholar
Ivanov, I. P., Simin, K., Letsou, A., Atkins, J. F. & Gesteland, R. F. The Drosophila gene for antizyme requires ribosomal frameshifting for expression and contains an intronic gene for snRNP Sm D3 on the opposite strand. Mol. Cell. Biol.18, 1553–1561 (1998) ArticleCASPubMedPubMed Central Google Scholar
Persengiev, S. P., Zhu, X. & Green, M. R. Nonspecific, concentration-dependent stimulation and repression of mammalian gene expression by small interfering RNAs (siRNAs). RNA10, 12–18 (2004) ArticleCASPubMedPubMed Central Google Scholar
Binder, R., Hwang, S. P., Ratnasabapathy, R. & Williams, D. L. Degradation of apolipoprotein II mRNA occurs via endonucleolytic cleavage at 5′-AAU-3′/5′-UAA-3′ elements in single-stranded loop domains of the 3′-noncoding region. J. Biol. Chem.264, 16910–16918 (1989) CASPubMed Google Scholar
Binder, R. et al. Evidence that the pathway of transferrin receptor mRNA degradation involves an endonucleolytic cleavage within the 3′ UTR and does not involve poly(A) tail shortening. EMBO J.13, 1969–1980 (1994) ArticleCASPubMedPubMed Central Google Scholar
Bremer, K. A., Stevens, A. & Schoenberg, D. R. An endonuclease activity similar to Xenopus PMR1 catalyzes the degradation of normal and nonsense-containing human beta-globin mRNA in erythroid cells. RNA9, 1157–1167 (2003) ArticleCASPubMedPubMed Central Google Scholar
Brown, B. D. & Harland, R. M. Endonucleolytic cleavage of a maternal homeo box mRNA in Xenopus oocytes. Genes Dev.4, 1925–1935 (1990) ArticleCASPubMed Google Scholar
Chernokalskaya, E. et al. A polysomal ribonuclease involved in the destabilization of albumin mRNA is a novel member of the peroxidase gene family. RNA4, 1537–1548 (1998) ArticleCASPubMedPubMed Central Google Scholar
Cunningham, K. S., Dodson, R. E., Nagel, M. A., Shapiro, D. J. & Schoenberg, D. R. Vigilin binding selectively inhibits cleavage of the vitellogenin mRNA 3′-untranslated region by the mRNA endonuclease polysomal ribonuclease 1. Proc. Natl Acad. Sci. USA97, 12498–12502 (2000) ArticleADSCASPubMedPubMed Central Google Scholar
Gallouzi, I. E. et al. A novel phosphorylation-dependent RNase activity of GAP-SH3 binding protein: a potential link between signal transduction and RNA stability. Mol. Cell. Biol.18, 3956–3965 (1998) ArticleCASPubMedPubMed Central Google Scholar
Lee, C. H., Leeds, P. & Ross, J. Purification and characterization of a polysome-associated endoribonuclease that degrades c-myc mRNA in vitro. J. Biol. Chem.273, 25261–25271 (1998) ArticleCASPubMed Google Scholar
Lim, S. K. & Maquat, L. E. Human beta-globin mRNAs that harbor a nonsense codon are degraded in murine erythroid tissues to intermediates lacking regions of exon I or exons I and II that have a cap-like structure at the 5′ termini. EMBO J.11, 3271–3278 (1992) ArticleCASPubMedPubMed Central Google Scholar
Scheper, W., Meinsma, D., Holthuizen, P. E. & Sussenbach, J. S. Long-range RNA interaction of two sequence elements required for endonucleolytic cleavage of human insulin-like growth factor II mRNAs. Mol. Cell. Biol.15, 235–245 (1995) ArticleCASPubMedPubMed Central Google Scholar
Stevens, A. et al. β-Globin mRNA decay in erythroid cells: UG site-preferred endonucleolytic cleavage that is augmented by a premature termination codon. Proc. Natl Acad. Sci. USA99, 12741–12746 (2002) ArticleADSCASPubMedPubMed Central Google Scholar
van Dijk, E. L., Sussenbach, J. S. & Holthuizen, P. E. Identification of RNA sequences and structures involved in site-specific cleavage of IGF-II mRNAs. RNA4, 1623–1635 (1998) ArticleCASPubMedPubMed Central Google Scholar
Wang, Z. & Kiledjian, M. Identification of an erythroid-enriched endoribonuclease activity involved in specific mRNA cleavage. EMBO J.19, 295–305 (2000) ArticlePubMedPubMed Central Google Scholar
Dykxhoorn, D. M., Novina, C. D. & Sharp, P. A. Killing the messenger: short RNAs that silence gene expression. Nature Rev. Mol. Cell Biol.4, 457–467 (2003) ArticleCAS Google Scholar
Hayes, C. S. & Sauer, R. T. Cleavage of the A site mRNA codon during ribosome pausing provides a mechanism for translational quality control. Mol. Cell12, 903–911 (2003) ArticleCASPubMed Google Scholar
Sunohara, T., Jojima, K., Yamamoto, Y., Inada, T. & Aiba, H. Nascent-peptide-mediated ribosome stalling at a stop codon induces mRNA cleavage resulting in nonstop mRNA that is recognized by tmRNA. RNA10, 378–386 (2004) ArticleCASPubMedPubMed Central Google Scholar
Gatfield, D., Unterholzner, L., Ciccarelli, F. D., Bork, P. & Izaurralde, E. Nonsense-mediated mRNA decay in Drosophila: at the intersection of the yeast and mammalian pathways. EMBO J.22, 3960–3970 (2003) ArticleCASPubMedPubMed Central Google Scholar
Bunch, T. A., Grinblat, Y. & Goldstein, L. S. Characterization and use of the Drosophila metallothionein promoter in cultured Drosophila melanogaster cells. Nucleic Acids Res.16, 1043–1061 (1988) ArticleCASPubMedPubMed Central Google Scholar