Thyberg, J. & Moskalewski, S. Role of microtubules in the organization of the Golgi complex. Exp. Cell Res.246, 263–279 (1999). CASPubMed Google Scholar
Ho, W. C., Allan, V. J., van Meer, G., Berger, E. G. & Kreis, T. E. Reclustering of scattered Golgi elements occurs along microtubules. Eur. J. Cell Biol.48, 250–263 (1989). CASPubMed Google Scholar
Rogaliski, A., Bergmann, J. & Singer, S. Effect of microtubule assembly status on the intracellular processing and surface expression of an integral protein of the plasma membrane. J. Cell Biol.99, 1101–1109 (1984). Google Scholar
Cooper, M. S., Cornell-Bell, A. H., Chernjavsky, A., Dani, J. W. & Smith, S. J. Tubulovesicular processes emerge from _trans_-Golgi cisternae, extend along microtubules, and interlink adjacent _trans_-Golgi elements into a reticulum. Cell61, 135–145 (1990). CASPubMed Google Scholar
Susalka, S., Hancock, W. & Pfister, K. Distinct cytoplasmic dynein complexes are transported by different mechanisms in axons. Biochim. Biophys. Acta1496, 76–88 (2000). CASPubMed Google Scholar
King, S. The dynein microtubule motor. Biochim. Biophys. Acta1496, 60–75 (2000). CASPubMed Google Scholar
Roghi, C. & Allan, V. Dynamic association of cytoplasmic dynein heavy chain 1a with the Golgi apparatus and intermediate compartment. J. Cell Sci.112, 4673–4685 (1999). CASPubMed Google Scholar
Tai, A. W., Chuang, J.-Z. & Sung, C.-H. Localization of Tctex-1, a cytoplasmic dynein light chain, to the Golgi apparatus and evidence for dynein complex heterogeneity. J. Biol. Chem.273, 19639–19649 (1998). CASPubMed Google Scholar
Habermann, A., Schroer, T., Griffiths, G. & Burkhardt, J. Immunolocalization of cytoplasmic dynein and dynactin subunits in cultured macrophages: enrichment on early endocytic organelles. J. Cell Sci.114, 229–240 (2001). CASPubMed Google Scholar
Sodeik, B., Ebersold, M. & Helenius, A. Microtubule-mediated transport of incoming herpes simplex virus 1 capsids to the nucleus. J. Cell Biol.136, 1007–1021 (1997). CASPubMedPubMed Central Google Scholar
Burkhardt, J., Echeverri, C., Nilsson, T. & Vallee, R. Overexpression of the Dynamitin (p50) subunit of the dynactin complex disrupts dynein-dependent maintenance of membrane organelle distribution. J. Cell Biol.139, 469–484 (1997). CASPubMedPubMed Central Google Scholar
Lippincott-Schwartz, J. et al. Microtubule-dependent retrograde transport of proteins into the ER in the presence of Brefeldin A suggests an ER recycling pathway. Cell60, 821–836 (1990). CASPubMed Google Scholar
Harada, A. et al. Golgi vesiculation and lysosome dispersion in cells lacking cytoplasmic dynein. J. Cell Biol.141, 51–59 (1998). CASPubMedPubMed Central Google Scholar
Vaughan, P., Lesyzk, J. & Vaughan, K. Cytoplasmic dynein intermediate chain phosphorylation regulates binding to dynactin. J. Biol. Chem.276, 26171–26179 (2001). CASPubMed Google Scholar
Presley, J. F. et al. ER-to-Golgi transport visualized in living cells. Nature389, 81–85 (1997). CASPubMed Google Scholar
Stephens, D. J. & Pepperkok, R. Imaging of procollagen transport reveals COPI-dependent cargo sorting during ER-to-Golgi transport in mammalian cells. J. Cell Sci.115, 1149–1160 (2002). CASPubMed Google Scholar
King, S. & Schroer, T. Dynactin increases the processivity of the cytoplasmic dynein motor. Nature Cell Biol.2, 20–24 (1999). Google Scholar
Schroer, T. Structure and function of dynactin. Seminars Cell Dev. Biol.7, 321–328 (1996). CAS Google Scholar
Karki, S. & Holzbaur, E. Cytoplasmic dynein and dynactin in cell division and intracellular transport. Curr. Opin. Cell Biol.11, 45–53 (1999). CASPubMed Google Scholar
Fouquet, J., Kann, M., Soues, S. & Melki, R. ARP1 in Golgi organisation and attachment of manchette microtubules to the nucleus during mammalian spermatogenesis. J. Cell Sci.113, 877–886 (2000). CASPubMed Google Scholar
Holleran, E. et al. βIII spectrin binds to the Arp1 subunit of dynactin. J. Biol. Chem.276, 36598–36605 (2001). CASPubMed Google Scholar
Holleran, E. A., Tokito, M. K., Karki, S. & Holzbaur, E. L. F. Centractin (ARP1) associates with spectrin revealing a potential mechanism to link dynactin to intracellular organelles. J. Cell Biol.135, 1815–1829 (1996). CASPubMed Google Scholar
Devarajan, P., Stabach, P., DeMatteis, M. & Morrow, J. Na,K-ATPase transport from endoplasmic reticulum to Golgi requires the Golgi spectrin ankyrin G119 skeleton in Madin Darby canine kidney cells. Proc. Natl Acad. Sci. USA94, 10711–10716 (1997). CASPubMedPubMed Central Google Scholar
Stankewich, M. et al. A widely expressed βIII spectrin associated with Golgi and cytoplasmic vesicles. Proc. Natl Acad. Sci. USA95, 14158–14163 (1998). CASPubMedPubMed Central Google Scholar
Echeverri, C. J., Paschal, B. M., Vaughan, K. T. & Vallee, R. B. Molecular characterisation of the 50-kD subunit of dynactin reveals function for the complex in chromosome alignment and spindle organisation during mitosis. J. Cell Biol.132, 617–633 (1996). ArticleCASPubMed Google Scholar
Quintyne, N. et al. Dynactin is required for microtubule anchoring at centrosomes. J. Cell Biol.147, 321–334 (1999). CASPubMedPubMed Central Google Scholar
Valetti, C. et al. Role of dynactin in endocytic traffic: effects of dynamitin overexpression and colocalization with CLIP-170. Mol. Biol. Cell10, 4107–4120 (1999). CASPubMedPubMed Central Google Scholar
Tynan, S. H., Purohit, A., Doxsey, S. J. & Vallee, R. B. Light intermediate chain 1 defines a functional subfraction of cytoplasmic dynein which binds to pericentrin. J. Biol. Chem.275, 32763–32768 (2000). CASPubMed Google Scholar
Tai, A., Chuang, J.-Z. & Sung, C.-H. Cytoplasmic dynein regulation by subunit heterogeneity and its role in apical transport. J. Cell Biol.153, 1499–1509 (2001). CASPubMedPubMed Central Google Scholar
Hoogenraad, C. C. et al. Mammalian Golgi-associated Bicaudal-D2 functions in the dynein–dynactin pathway by interacting with these complexes. EMBO J.20, 4041–4054 (2001). CASPubMedPubMed Central Google Scholar
Vaisberg, E. A., Grissom, P. M. & McIntosh, J. R. Mammalian cells express three distinct dynein heavy chains that are localized to different cytoplasmic organelles. J. Cell Biol.133, 831–842 (1996). CASPubMed Google Scholar
Grissom, P., Vaisberg, E. & McIntosh, J. Identification of a novel light intermediate chain (D2LIC) for mammalian cytoplasmic dynein. Mol. Biol. Cell13, 817–829 (2002). CASPubMedPubMed Central Google Scholar
Miki, H., Setou, M., Kaneshiro, K. & Hirokawa, N. All kinesin superfamily protein, KIF, genes in mouse and human. Proc. Natl Acad. Sci. USA98, 7004–7011 (2001). CASPubMedPubMed Central Google Scholar
Bloom, G. & Endow, S. Motor proteins 1: kinesins. Protein Profile2, 1105–1171 (1995). CASPubMed Google Scholar
Vallee, R. & Sheetz, M. Targeting of motor proteins. Science271, 1539–1544 (1996). CASPubMed Google Scholar
Hirokawa, N. Kinesin and dynein superfamily proteins and the mechanism of organelle transport. Science279, 519–526 (1998). CASPubMed Google Scholar
Marks, D., Larkin, J. & McNiven, M. Association of kinesin with the Golgi apparatus in rat hepatocytes. J. Cell. Sci.107, 2417–2426 (1994). CASPubMed Google Scholar
Johnson, K., Hall, E. & Boekelheide, K. Kinesin localizes to the _trans_-Golgi network regardless of microtubule organization. Eur. J. Cell Biol.69, 276–287 (1996). CASPubMed Google Scholar
Gyoeva, F., Bybikova, E. & Minin, A. An isoform of kinesin light chain specific for the Golgi complex. J. Cell Sci.113, 2047–2054 (2000). CASPubMed Google Scholar
Feiguin, F., Ferreira, A., Kosik, K. S. & Caceres, A. Kinesin-mediated organelle translocation revealed by specific cellular manipulations. J. Cell Biol.127, 1021–1039 (1994). CASPubMed Google Scholar
Girod, A. et al. Evidence for a COP-I-independent transport route from the Golgi complex to the endoplasmic reticulum. Nature Cell Biol.1, 423–430 (1999). CASPubMed Google Scholar
White, J. et al. Rab6 coordinates a novel Golgi to ER retrograde transport pathway in live cells. J. Cell Biol.147, 743–759 (1999). CASPubMedPubMed Central Google Scholar
Dorner, C. et al. Characterization of KIF1C, a new kinesin-like protein involved in vesicle transport from the Golgi apparatus to the endoplasmic reticulum. J. Biol. Chem.273, 20267–20275 (1998). CASPubMed Google Scholar
Nakajima, K. et al. Molecular motor KIF1C is not essential for mouse survival and motor-dependent retrograde Golgi apparatus-to-endoplasmic reticulum transport. Mol. Cell. Biol.22, 866–873 (2002). CASPubMedPubMed Central Google Scholar
Le Bot, N., Antony, C., White, J., Karsenti, E. & Vernos, I. Role of xklp3, a subunit of the Xenopus kinesin II heterotrimeric complex, in membrane transport between the endoplasmic reticulum and the Golgi apparatus. J. Cell Biol.143, 1559–1573 (1998). CASPubMedPubMed Central Google Scholar
Yang, Z. & Goldstein, L. S. B. Characterization of the KIF3C neural kinesin-like motor from mouse. Mol. Biol. Cell9, 249–261 (1998). CASPubMedPubMed Central Google Scholar
Marra, P. et al. The GM130 and GRASP65 Golgi proteins cycle through and define a subdomain of the intermediate compartment. Nature Cell Biol.3, 1101–1113 (2001). CASPubMed Google Scholar
Robertson, A. & Allan, V. Brefeldin A-dependent membrane tubule formation reconstituted in vitro is driven by a cell cycle-regulated microtubule motor. Mol. Biol. Cell11, 941–955 (2000). CASPubMedPubMed Central Google Scholar
Martinez, O. et al. GTP-bound forms of rab6 induce the redistribution of Golgi proteins into the endoplasmic reticulum. Proc. Natl Acad. Sci. USA94, 1828–1833 (1997). CASPubMedPubMed Central Google Scholar
Echard, A. et al. Interaction of a Golgi-associated kinesin-like protein with Rab6. Science279, 580–585 (1998). CASPubMed Google Scholar
Opdam, F. et al. The small GTPase Rab6B, a novel Rab6 subfamily member, is cell-type specifically expressed and localised to the Golgi apparatus. J. Cell. Sci.113, 2725–2735 (2000). CASPubMed Google Scholar
Hill, E., Clarke, M. & Barr, F. The Rab6-binding kinesin, Rab6-KIFL, is required for cytokinesis. EMBO J.19, 5711–5719 (2000). CASPubMedPubMed Central Google Scholar
Fontijn, R. et al. The human kinesin-like protein RB6K is under tight cell cycle control and is essential for cytokinesis. Mol. Cell. Biol.21, 2944–2955 (2001). CASPubMedPubMed Central Google Scholar
Lane, J. & Allan, V. Microtubule-based membrane movement. Biochim. Biophys. Acta1376, 27–55 (1998). CASPubMed Google Scholar
Kamal, A. & Goldstein, L. Principles of cargo attachment to cytoplasmic motor proteins. Curr. Opin. Cell Biol.14, 63–68 (2002). CASPubMed Google Scholar
Nelson, W. & Yeaman, C. Protein trafficking in the exocytic pathway of polarized epithelial cells. Trends Cell Biol.11, 483–486 (2001). CASPubMed Google Scholar
McNiven, M. A. & Marlowe, K. J. Contributions of molecular motor enzymes to vesicle-based protein transport in gastrointestinal epithelial cells. Gastroenterology116, 438–451 (1999). CASPubMed Google Scholar
Lafont, F. & Simons, K. The role of microtubule-based motors in the exocytic transport of polarized cells. Semin. Cell Dev. Biol.7, 343–355 (1996). CAS Google Scholar
Noda, Y. et al. KIFC3, a microtubule minus end-directed motor for the apical transport of annexin XIIIb-associated triton-insoluble membranes. J. Cell Biol.155, 77–88 (2001). CASPubMedPubMed Central Google Scholar
Keller, P., Toomre, D., Diaz, E., White, J. & Simons, K. Multicolour imaging of post-Golgi sorting and trafficking in live cells. Nature Cell Biol.3, 140–149 (2001). CASPubMed Google Scholar
Klopfenstein, D., Tomishige, M., Stuurman, N. & Vale, R. Role of phosphatidylinositol(4,5)bisphosphate organization in membrane transport by the Unc104 kinesin motor. Cell109, 347–358 (2002). CASPubMedPubMed Central Google Scholar
Valderrama, F. et al. Actin microfilaments are essential for the cytological positioning and morphology of the Golgi complex. Eur. J. Cell Biol.76, 9–17 (1998). CASPubMed Google Scholar
di Campli, A. et al. Morphological changes in the Golgi complex correlate with actin cytoskeleton rearrangements. Cell Motil. Cytoskeleton43, 334–348 (1999). CASPubMed Google Scholar
Holleran, E. A. & Holzbaur, E. L. F. Speculating about spectrin: new insights into the Golgi-associated cytoskeleton. Trends Cell Biol.8, 26–29 (1998). CASPubMed Google Scholar
Fath, K. R., Trimbur, G. M. & Burgess, D. R. Molecular motors and a spectrin matrix associate with Golgi membranes in vitro. J. Cell Biol.139, 1169–1181 (1997). CASPubMedPubMed Central Google Scholar
Stow, J. L. & Heimann, K. Vesicle budding on Golgi membranes: regulation by G proteins and myosin motors. Biochim. Biophys. Acta1404, 161–171 (1998). CASPubMed Google Scholar
DePina, A. S. & Langford, G. M. Vesicle transport: the role of actin filaments and myosin motors. Microsc. Res. Tech.47, 93–106 (1999). CASPubMed Google Scholar
Drenckhahn, D. & Dermietzel, R. Organization of the actin filament cytoskeleton in the intestinal brush border: a quantitative and qualitative immunoelectron microscope study. J. Cell Biol.107, 1037–1048 (1988). CASPubMed Google Scholar
Fath, K. R. & Burgess, D. R. Golgi-derived vesicles from developing epithelial cells bind actin filaments and possess myosin-I as a cytoplasmically oriented peripheral membrane protein. J. Cell Biol.120, 117–127 (1993). CASPubMed Google Scholar
Fath, K. R., Trimbur, G. M. & Burgess, D. R. Molecular motors are differentially distributed on Golgi membranes from polarized epithelial cells. J. Cell Biol.126, 661–675 (1994). CASPubMed Google Scholar
Montes de Oca, G., Lezama, R. A., Mondragon, R., Castillo, A. M. & Meza, I. Myosin I interactions with actin filaments and _trans_-Golgi-derived vesicles in MDCK cell monolayers. Arch. Med. Res.28, 321–328 (1997). CASPubMed Google Scholar
Balish, M. F., Moeller, E. F. & Coluccio, L. M. Overlapping distribution of the 130- and 110-kDa myosin I isoforms on rat liver membranes. Arch. Biochem. Biophys.370, 285–293 (1999). CASPubMed Google Scholar
Narula, N. et al. Identification of a 200-kD, brefeldin-sensitive protein on Golgi membranes. J. Cell Biol.114, 1113–1124 (1992). Google Scholar
Narula, N. & Stow, J. L. Distinct coated vesicles labeled for p200 bud from _trans_-Golgi network membranes. Proc. Natl Acad. Sci. USA92, 2874–2878 (1995). CASPubMedPubMed Central Google Scholar
Ikonen, E., Parton, R. G., Lafont, F. & Simons, K. Analysis of the role of p200 containing vesicles in post-Golgi traffic. Mol. Biol. Cell7, 961–974 (1996). CASPubMedPubMed Central Google Scholar
Ikonen, E. et al. Myosin II is associated with Golgi membranes: identification of p200 as nonmuscle myosin II on Golgi-derived vesicles. J. Cell Sci.110, 2155–2164 (1997). CASPubMed Google Scholar
Müsch, A., Cohen, D. & Rodriguez-Boulan, E. Myosin II is involved in the production of constitutive transport vesicles from the TGN. J. Cell. Biol.138, 291–306 (1997). PubMedPubMed Central Google Scholar
Stow, J. L., Fath, K. R. & Burgess, D. R. Budding roles for myosin II on the Golgi. Trends Cell Biol.8, 138–141 (1998). CASPubMed Google Scholar
Reck-Peterson, S. L., Provance, D. W. J., Mooseker, M. S. & Mercer, J. A. Class V myosins. Biochim. Biophys. Acta1496, 36–51 (2000). CASPubMed Google Scholar
Cheney, R. E. et al. Brain myosin-V is a two-headed unconventional myosin with motor activity. Cell75, 13–23 (1993). CASPubMed Google Scholar
Nascimento, A. A. C., Cheney, R. E., Tauhata, S. B. F., Larson, R. E. & Mooseker, M. S. Enzymatic characterization and functional domain mapping of brain myosin-V. J. Biol. Chem.271, 17561–17569 (1996). CASPubMed Google Scholar
Johnston, G. C., Prendergast, J. A. & Singer, R. A. The Saccharomyces cerevisiae MYO2 gene encodes an essential myosin for vectorial transport of vesicles. J. Cell Biol.113, 539–551 (1991). CASPubMed Google Scholar
Govindan, B., Bowser, R. & Novick, R. The role of Myo2, a yeast class V myosin, in vesicular transport. J. Cell Biol.128, 1055–1068 (1995). CASPubMed Google Scholar
Reck-Peterson, S. L., Novick, P. J. & Mooseker, M. S. The tail of a yeast class V myosin, Myo2p, functions as a localization domain. Mol. Biol. Cell10, 1001–1017 (1999). CASPubMedPubMed Central Google Scholar
Fukuda, M., Kuroda, T. S. & Mikoshiba, K. Slac2-a/melanophilin, the missing link between Rab27 and myosin Va: implications of a tripartite protein complex for melanosome transport. J. Biol. Chem.277, 12432–12436 (2002). CASPubMed Google Scholar
Wu, X. S. et al. Identification of an organelle receptor for myosin-Va. Nature Cell Biol.4, 271–278 (2002). CASPubMed Google Scholar
Huang, J. D. et al. Direct interaction of microtubule- and actin-based transport motors. Nature397, 267–270 (1999). CASPubMed Google Scholar
Wells, A. L. et al. Myosin VI is an actin-based motor that moves backwards. Nature401, 505–508 (1999). CASPubMed Google Scholar
Cramer, L. P. Myosin VI: roles for a minus end-directed actin motor in cells. J. Cell Biol.150, F121–F126 (2000). CASPubMed Google Scholar
Buss, F. et al. The localization of myosin VI at the Golgi complex and leading edge of fibroblasts and its phosphorylation and recruitment into membrane ruffles of A431 cells after growth factor stimulation. J. Cell Biol.143, 1535–1545 (1998). CASPubMedPubMed Central Google Scholar
Buss, F., Arden, S. D., Lindsay, M., Luzio, J. P. & Kendrick-Jones, J. Myosin VI isoform localized to clathrin-coated vesicles with a role in clathrin-mediated endocytosis. EMBO J.20, 3676–3684 (2001). CASPubMedPubMed Central Google Scholar
Marks, B. et al. GTPase activity of dynamin and resulting conformation change are essential for endocytosis. Nature410, 231–235 (2001). CASPubMed Google Scholar
Sweitzer, S. M. & Hinshaw, J. E. Dynamin undergoes a GTP-dependent conformational change causing vesiculation. Cell93, 1021–1029 (1998). CASPubMed Google Scholar
McNiven, M. A. Dynamin: A molecular motor with pinchase action. Cell94, 151–154 (1998). CASPubMed Google Scholar
McNiven, M. A., Cao, H., Pitts, K. R. & Yoon, Y. The dynamin family of mechanoenzymes: pinching in new places. Trends Biochem. Sci.25, 115–120 (2000). CASPubMed Google Scholar
Henley, J. R. & McNiven, M. A. Association of a dynamin-like protein with the Golgi apparatus in mammalian cells. J. Cell Biol.133, 761–775 (1996). CASPubMed Google Scholar
Jones, S. M., Howell, K. E., Henley, J. R., Cao, H. & McNiven, M. A. Role of dynamin in the formation of transport vesicles from the _trans_-Golgi network. Science279, 573–577 (1998). CASPubMed Google Scholar
Kreitzer, G., Marmorstein, A., Okamoto, P., Vallee, R. & Rodriguez-Boulin, E. Kinesin and dynamin are required for post-Golgi transport of a plasma-membrane protein. Nature Cell Biol.2, 125–127 (2000). CASPubMed Google Scholar
Cao, H., Thompson, H. M., Krueger, E. W. & McNiven, M. A. Disruption of Golgi structure and function in mammalian cells expressing a mutant dynamin. J. Cell Sci.113, 1993–2002 (2000). CASPubMed Google Scholar