Common variants on chromosomes 2q35 and 16q12 confer susceptibility to estrogen receptor–positive breast cancer (original) (raw)

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Acknowledgements

We thank all participants for taking part in this research. We thank S. Sveinsdottir and K. Alexiusdottir for assistance in recruitment of patients and collection of clinical information. This project was funded in part by contract number 018827 (POLYGENE) from the 6th Framework Program of the European Union, the Swedish Cancer Society, the Gustav V Jubilee Foundation, the Bert von Kantzow Foundation and the Nilsson-Ehle Foundation.

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Authors and Affiliations

1. deCODE genetics, Sturlugata 8, Reykjavik, 101, Iceland
   Simon N Stacey, Andrei Manolescu, Patrick Sulem, Thorunn Rafnar, Julius Gudmundsson, Sigurjon A Gudjonsson, Gisli Masson, Margret Jakobsdottir, Steinunn Thorlacius, Agnar Helgason, Magali Mouy, Jona Saemundsdottir, Valgerdur M Backman, Larus Gudmundsson, Kristleifur Kristjansson, Jon T Bergthorsson, Jelena Kostic, Michael L Frigge, Frank Geller, Daniel Gudbjartsson, Jeffrey R Gulcher, Unnur Thorsteinsdottir, Augustine Kong & Kari Stefansson
2. Comprehensive Cancer Center IKO, Nijmegen, 6501 BG, The Netherlands
   Katja K Aben
3. Departments of Epidemiology and Biostatistics and Clinical Chemistry, Radboud University Nijmegen Medical Center, Nijmegen, 6500 HB, The Netherlands
   Katja K Aben, Dorine W Swinkels & Lambertus A Kiemeney
4. Department of Surgery, Canisius Wilhelmina Hospital, Nijmegen, 6500, GS, The Netherlands
   Luc J Strobbe
5. INR Thrombosis Service, 6525 GA Nijmegen, The Netherlands.,
   Marjo T Albers-Akkers
6. Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, 90033, California, USA
   Brian E Henderson & Christopher A Haiman
7. Cancer Research Center, University of Hawaii, Honolulu, 96813, Hawaii, USA
   Laurence N Kolonel & Loic Le Marchand
8. Division of Medical Oncology, University Hospital, Av. San Juan Bosco 15, Zaragoza, 50009, Spain
   Esther Millastre, Raquel Andres, Alejandro Tres & Jose I Mayordomo
9. Health Science Institute, Nanotechnology Institute of Aragon, Zaragoza, Spain
   Javier Godino
10. Division of Pathology, San Jorge General Hospital, Av. Martínez de Velasco 38, Huesca, 22004, Spain
    Maria Dolores Garcia-Prats
11. Division of Medical Oncology, Ernest Lluch Hospital, Calatayud, 50300, Spain
    Eduardo Polo
12. Departments of Oncology, Surgery and Radiation Physics, Landspitali-University Hospital, 101 Reykjavik, Iceland
    Helgi Sigurdsson, Thora Jonsdottir, Jon Hrafnkelsson, Jakob Johannsson, Thorarinn Sveinsson, Gardar Myrdal, Hlynur Niels Grimsson, Thorvaldur Jonsson & Oskar Th Johannsson
13. Department of Molecular Medicine, Karolinska Institute, Stockholm, S171 76, Sweden
    Susanna von Holst, Barbro Werelius & Annika Lindblom
14. Department of Oncology, Karolinska University Hospital at Södersjukhuset, Stockholm, S118 83, Sweden
    Sara Margolin

Authors

1. Simon N Stacey
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2. Andrei Manolescu
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3. Patrick Sulem
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4. Thorunn Rafnar
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5. Julius Gudmundsson
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6. Sigurjon A Gudjonsson
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7. Gisli Masson
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8. Margret Jakobsdottir
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9. Steinunn Thorlacius
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10. Agnar Helgason
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11. Katja K Aben
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12. Luc J Strobbe
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13. Marjo T Albers-Akkers
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14. Dorine W Swinkels
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15. Brian E Henderson
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16. Laurence N Kolonel
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17. Loic Le Marchand
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18. Esther Millastre
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19. Raquel Andres
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20. Javier Godino
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21. Maria Dolores Garcia-Prats
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22. Eduardo Polo
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23. Alejandro Tres
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24. Magali Mouy
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25. Jona Saemundsdottir
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26. Valgerdur M Backman
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27. Larus Gudmundsson
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28. Kristleifur Kristjansson
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29. Jelena Kostic
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30. Michael L Frigge
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31. Frank Geller
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32. Daniel Gudbjartsson
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33. Helgi Sigurdsson
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34. Thora Jonsdottir
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35. Jon Hrafnkelsson
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36. Jakob Johannsson
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37. Thorarinn Sveinsson
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38. Gardar Myrdal
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39. Hlynur Niels Grimsson
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40. Thorvaldur Jonsson
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41. Susanna von Holst
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42. Barbro Werelius
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43. Sara Margolin
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44. Annika Lindblom
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45. Jose I Mayordomo
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46. Christopher A Haiman
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47. Lambertus A Kiemeney
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48. Oskar Th Johannsson
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49. Jeffrey R Gulcher
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50. Unnur Thorsteinsdottir
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51. Augustine Kong
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52. Kari Stefansson
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Corresponding authors

Correspondence toSimon N Stacey or Kari Stefansson.

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Competing interests

Simon N Stacey, Andrei Manolescu, Patrick Sulem, Thorunn Rafnar, Julius Gudmundsson, Sigurjon A Gudjonsson, Gisli Masson, Margret Jakobsdottir, Steinunn Thorlacius, Agnar Helgason, Magali Mouy, Jona Saemundsdottir, Valgerdur M Backman, Larus Gudmundsson, Kristleifur Kristjansson, Jon T Bergthorsson, Jelena Kostic, Michael L Frigge, Frank Geller, Daniel Gudbjartsson, Jeffrey R Gulcher, Unnur Thorsteinsdottir, Augustine Kong and Kari Stefansson are employees and/or shareholders of deCODE genetics.

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Stacey, S., Manolescu, A., Sulem, P. et al. Common variants on chromosomes 2q35 and 16q12 confer susceptibility to estrogen receptor–positive breast cancer.Nat Genet 39, 865–869 (2007). https://doi.org/10.1038/ng2064

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• Received: 04 April 2007
• Accepted: 10 May 2007
• Published: 27 May 2007
• Issue Date: July 2007
• DOI: https://doi.org/10.1038/ng2064