Memory CD8+ T cells vary in differentiation phenotype in different persistent virus infections (original) (raw)
Koup, R.A. et al. Temporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndrome. J. Virol.68, 4650–4655 (1994). CASPubMed Central Google Scholar
Callan, M.F. et al. Large clonal expansions of CD8+ T cells in acute infectious mononucleosis. Nature Med.2, 906–911 (1996). ArticleCAS Google Scholar
Wills, M.R. et al. The human cytotoxic T-lymphocyte (CTL) response to cytomegalovirus is dominated by structural protein pp65: frequency, specificity, and T-cell receptor usage of pp65-specific CTL. J. Virol.70, 7569–7579 (1996). CASPubMed Central Google Scholar
Lechner, F. et al. CD8+ T lymphocyte responses are induced during acute hepatitis C virus infection but are not sustained. Eur. J. Immunol.30, 2479–2487 (2000). ArticleCAS Google Scholar
Appay, V. et al. HIV-specific CD8(+) T cells produce antiviral cytokines but are impaired in cytolytic function. J. Exp. Med.192, 63–75 (2000). ArticleCAS Google Scholar
Gillespie, G.M. et al. Functional heterogeneity and high frequencies of cytomegalovirus-specific CD8(+) T lymphocytes in healthy seropositive donors. J. Virol.74, 8140–8150 (2000). ArticleCAS Google Scholar
Hislop, A.D. et al. EBV-specific CD8+ T cell memory: relationships between epitope specificity, cell phenotype, and immediate effector function. J. Immunol.167, 2019–2029 (2001). ArticleCAS Google Scholar
Lechner, F. et al. Analysis of successful immune responses in persons infected with hepatitis C virus. J. Exp. Med.191, 1499–1512 (2000). ArticleCAS Google Scholar
Effros, R.B. et al. Shortened telomeres in the expanded CD28−CD8+ cell subset in HIV disease implicate replicative senescence in HIV pathogenesis. AIDS10, F17–22 (1996). ArticleCAS Google Scholar
Posnett, D.N., Edinger, J.W., Manavalan, J.S., Irwin, C. & Marodon, G. Differentiation of human CD8 T cells: implications for in vivo persistence of CD8+ CD28− cytotoxic effector clones. Int. Immunol.11, 229–241 (1999). ArticleCAS Google Scholar
Borthwick, N.J., Lowdell, M., Salmon, M. & Akbar, A.N. Loss of CD28 expression on CD8(+) T cells is induced by IL-2 receptor γ chain signalling cytokines and type I IFN, and increases susceptibility to activation-induced apoptosis. Int. Immunol.12, 1005–1013 (2000). ArticleCAS Google Scholar
Hamann, D. et al. Evidence that human CD8+CD45RA+CD27− cells are induced by antigen and evolve through extensive rounds of division. Int. Immunol.11, 1027–1033 (1999). ArticleCAS Google Scholar
Roos, M.T. et al. Changes in the composition of circulating CD8+ T cell subsets during acute Epstein–Barr and human immunodeficiency virus infections in humans. J. Infect. Dis.182, 451–458 (2000). ArticleCAS Google Scholar
Globerson, A. & Effros, R.B. Ageing of lymphocytes and lymphocytes in the aged. Immunol. Today21, 515–521 (2000). ArticleCAS Google Scholar
De Rosa, S.C., Herzenberg, L.A. & Roederer, M. 11-color, 13-parameter flow cytometry: identification of human naive T cells by phenotype, function, and T-cell receptor diversity. Nature Med.7, 245–248 (2001). ArticleCAS Google Scholar
Ahmed, R. & Gray, D. Immunological memory and protective immunity: Understanding their relation. Science272, 54–60 (1996). ArticleCAS Google Scholar
Doherty, P.C. & Christensen, J.P. Accessing complexity: The dynamics of virus-specific T cell responses. Annu. Rev. Immunol.18, 561–592 (2000). ArticleCAS Google Scholar
Bevan, M.J. & Fink, P.J. The CD8 response on autopilot. Nature Immunol.2, 381–382 (2001). ArticleCAS Google Scholar
Hu, H. et al. CD4(+) T cell effectors can become memory cells with high efficiency and without further division. Nature Immunol.2, 705–710 (2001). ArticleCAS Google Scholar
Hamann, D. et al. Phenotypic and functional separation of memory and effector human CD8+ T cells. J. Exp. Med.186, 1407–1418 (1997). ArticleCAS Google Scholar
Sallusto, F., Lenig, D., Forster, R., Lipp, M. & Lanzavecchia, A. Two subsets of memory T lymphocytes with distinct homing potentials and effector functions. Nature401, 708–712 (1999). ArticleCAS Google Scholar
Champagne, P. et al. Skewed maturation of memory HIV-specific CD8 T lymphocytes. Nature410, 106–111 (2001). ArticleCAS Google Scholar
Strasser, A., O'Connor, L. & Dixit, V.M. Apoptosis signaling. Annu. Rev. Biochem.69, 217–245 (2000). ArticleCAS Google Scholar
Lenschow, D.J., Walunas, T.L. & Bluestone, J.A. CD28/B7 system of T cell costimulation. Annu. Rev. Immunol.14, 233–258 (1996). ArticleCAS Google Scholar
Hendriks, J. et al. CD27 is required for generation and long-term maintenance of T cell immunity. Nature Immunol.1, 433–439 (2000). ArticleCAS Google Scholar
Ferbas, J. et al. Virus burden in long-term survivors of human immunodeficiency virus (HIV) infection is a determinant of anti-HIV CD8+ lymphocyte activity. J. Infect. Dis.172, 329–339 (1995). ArticleCAS Google Scholar
Medley, Q.G. et al. Characterization of GMP-17, a granule membrane protein that moves to the plasma membrane of natural killer cells following target cell recognition. Proc. Natl. Acad. Sci. USA93, 685–689 (1996). ArticleCAS Google Scholar
Campbell, J.J. et al. 6-C-kine (SLC), a lymphocyte adhesion-triggering chemokine expressed by high endothelium, is an agonist for the MIP-3β receptor CCR7. J. Cell Biol141, 1053–1059 (1998). ArticleCAS Google Scholar
Campbell, J.J. et al. Chemokines and the arrest of lymphocytes rolling under flow conditions. Science279, 381–384 (1998). ArticleCAS Google Scholar
Chen, G. et al. CD8 T cells specific for human immunodeficiency virus, Epstein–Barr virus, and cytomegalovirus lack molecules for homing to lymphoid sites of infection. Blood98, 156–164 (2001). ArticleCAS Google Scholar
Baars, P.A. et al. Cytolytic mechanisms and expression of activation-regulating receptors on effector-type CD8+CD45RA+CD27− human T cells. J. Immunol.165, 1910–1917 (2000). ArticleCAS Google Scholar
Callan, M.F. et al. CD8(+) T-cell selection, function, and death in the primary immune response in vivo. J. Clin. Invest.106, 1251–1261 (2000). ArticleCAS Google Scholar
Mueller, Y.M. et al. Increased CD95/Fas-induced apoptosis of HIV-specific CD8(+) T cells. Immunity15, 871–882 (2001). ArticleCAS Google Scholar
Ridge, J.P., Di Rosa, F. & Matzinger, P. A conditioned dendritic cell can be a temporal bridge between a CD4+ T-helper and a T-killer cell. Nature393, 474–478 (1998). ArticleCAS Google Scholar
Kalams, S.A. & Walker, B.D. The critical need for CD4 help in maintaining effective cytotoxic T lymphocyte responses. J. Exp. Med.188, 2199–2204 (1998). ArticleCAS Google Scholar
Andrews, D.M., Andoniou, C.E., Granucci, F., Ricciardi-Castagnoli, P. & Degli-Esposti, M.A. Infection of dendritic cells by murine cytomegalovirus induces functional paralysis. Nature Immunol.22, 22 (2001). Google Scholar
Grayson, J.M., Zajac, A.J., Altman, J.D. & Ahmed, R. Cutting edge: Increased expression of Bcl–2 in antigen-specific memory CD8+ T cells. J. Immunol.164, 3950–3954 (2000). ArticleCAS Google Scholar
Homann, D., Teyton, L. & Oldstone, M.B. Differential regulation of antiviral T-cell immunity results in stable CD8+ but declining CD4+ T-cell memory. Nature Med.7, 913–919 (2001). ArticleCAS Google Scholar
Kostense, S. et al. High viral burden in the presence of major HIV-specific CD8(+) T cell expansions: Evidence for impaired CTL effector function. Eur. J. Immunol.31, 677–686 (2001). ArticleCAS Google Scholar
Easterbrook, P.J. Long-term non-progression in HIV infection: Definitions and epidemiological issues. J. Infect.38, 71–73 (1999). ArticleCAS Google Scholar
Bunce, M. et al. Phototyping: Comprehensive DNA typing for HLA-A, B, C, DRB1, DRB3, DRB4, DRB5 & DQB1 by PCR with 144 primer mixes utilizing sequence-specific primers (PCR-SSP). Tissue Antigens46, 355–367 (1995). ArticleCAS Google Scholar
Altman, J.D. et al. Phenotypic analysis of antigen-specific T lymphocytes. Science274, 94–96 (1996); erratum: 280, 1821 (1998). ArticleCAS Google Scholar