Hemifusion in SNARE-mediated membrane fusion (original) (raw)

References

  1. White, J.M. Membrane fusion. Science 258, 917–924 (1992).
    Article CAS Google Scholar
  2. Skehel, J.J. & Wiley, D.C. Coiled coils in both intracellular vesicle and viral membrane fusion. Cell 95, 871–874 (1998).
    Article CAS Google Scholar
  3. Chan, D.C. & Kim, P.S. HIV entry and its inhibition. Cell 93, 681–684 (1998).
    Article CAS Google Scholar
  4. Jahn, R., Lang, T. & Sudhof, T.C. Membrane fusion. Cell 112, 519–533 (2003).
    Article CAS Google Scholar
  5. Earp, L.J., Delos, S.E., Park, H.E. & White, J.M. The many mechanisms of viral membrane fusion proteins. Curr. Top. Microbiol. Immunol. 285, 25–66 (2005).
    CAS PubMed Google Scholar
  6. Chernomordik, L.V. & Kozlov, M.M. Protein-lipid interplay in fusion and fission of biological membranes. Annu. Rev. Biochem. 72, 175–207 (2003).
    Article CAS Google Scholar
  7. Kemble, G.W., Danieli, T. & White, J.M. Lipid-anchored influenza hemagglutinin promotes hemifusion, not complete fusion. Cell 76, 383–391 (1994).
    Article CAS Google Scholar
  8. Melikyan, G.B., Markosyan, R.M., Roth, M.G. & Cohen, F.S. A point mutation in the transmembrane domain of the hemagglutinin of influenza virus stabilizes a hemifusion intermediate that can transit to fusion. Mol. Biol. Cell 11, 3765–3775 (2000).
    Article CAS Google Scholar
  9. Armstrong, R.T., Kushnir, A.S. & White, J.M. The transmembrane domain of influenza hemagglutinin exhibits a stringent length requirement to support the hemifusion to fusion transition. J. Cell Biol. 151, 425–437 (2000).
    Article CAS Google Scholar
  10. Yang, L. & Huang, H.W. Observation of a membrane fusion intermediate structure. Science 297, 1877–1879 (2002).
    Article CAS Google Scholar
  11. Rothman, J.E. Mechanisms of intracellular protein transport. Nature 372, 55–63 (1994).
    Article CAS Google Scholar
  12. Chen, Y.A., Scales, S.J., Patel, S.M., Doung, Y.C. & Scheller, R.H. SNARE complex formation is triggered by Ca2+ and drives membrane fusion. Cell 97, 165–174 (1999).
    Article CAS Google Scholar
  13. Weber, T. et al. SNAREpins: minimal machinery for membrane fusion. Cell 92, 759–772 (1998).
    Article CAS Google Scholar
  14. McNew, J.A. et al. Compartmental specificity of cellular membrane fusion encoded in SNARE proteins. Nature 407, 153–159 (2000).
    Article CAS Google Scholar
  15. Han, X., Wang, C.T., Bai, J., Chapman, E.R. & Jackson, M.B. Transmembrane segments of syntaxin line the fusion pore of Ca2+-triggered exocytosis. Science 304, 289–292 (2004).
    Article CAS Google Scholar
  16. Grote, E., Baba, M., Ohsumi, Y. & Novick, P.J. Geranylgeranylated SNAREs are dominant inhibitors of membrane fusion. J. Cell Biol. 151, 453–466 (2000).
    Article CAS Google Scholar
  17. Chernomordik, L.V. et al. Lysolipids reversibly inhibit Ca(2+)-, GTP- and pH-dependent fusion of biological membranes. FEBS Lett. 318, 71–76 (1993).
    Article CAS Google Scholar
  18. Peters, C. et al. Trans-complex formation by proteolipid channels in the terminal phase of membrane fusion. Nature 409, 581–588 (2001).
    Article CAS Google Scholar
  19. McNew, J.A. et al. Close is not enough: SNARE-dependent membrane fusion requires an active mechanism that transduces force to membrane anchors. J. Cell Biol. 150, 105–117 (2000).
    Article CAS Google Scholar
  20. Hubbell, W.L., Gross, A., Langen, R. & Lietzow, M.A. Recent advances in site-directed spin labeling of proteins. Curr. Opin. Struct. Biol. 8, 649–656 (1998).
    Article CAS Google Scholar
  21. Rabenstein, M.D. & Shin, Y.K. HIV-1 gp41 tertiary structure studied by EPR spectroscopy. Biochemistry 35, 13922–13928 (1996).
    Article CAS Google Scholar
  22. McHaourab, H.S., Lietzow, M.A., Hideg, K. & Hubbell, W.L. Motion of spin-labeled side chains in T4 lysozyme. Correlation with protein structure and dynamics. Biochemistry 35, 7692–7704 (1996).
    Article CAS Google Scholar
  23. Altenbach, C., Greenhalgh, D.A., Khorana, H.G. & Hubbell, W.L. A collision gradient method to determine the immersion depth of nitroxides in lipid bilayers: application to spin-labeled mutants of bacteriorhodopsin. Proc. Natl. Acad. Sci. USA 91, 1667–1671 (1994).
    Article CAS Google Scholar
  24. Macosko, J.C., Kim, C.H. & Shin, Y.K. The membrane topology of the fusion peptide region of influenza hemagglutinin determined by spin-labeling EPR. J. Mol. Biol. 267, 1139–1148 (1997).
    Article CAS Google Scholar
  25. Chen, Y., Xu, Y., Zhang, F. & Shin, Y.K. Constitutive versus regulated SNARE assembly: a structural basis. EMBO J. 23, 681–689 (2004).
    Article CAS Google Scholar
  26. Rossi, G., Salminen, A., Rice, L.M., Brunger, A.T. & Brennwald, P. Analysis of a yeast SNARE complex reveals remarkable similarity to the neuronal SNARE complex and a novel function for the C terminus of the SNAP-25 homolog, Sec9. J. Biol. Chem. 272, 16610–16617 (1997).
    Article CAS Google Scholar
  27. Meers, P., Ali, S., Erukulla, R. & Janoff, A.S. Novel inner monolayer fusion assays reveal differential monolayer mixing associated with cation-dependent membrane fusion. Biochim. Biophys. Acta 1467, 227–243 (2000).
    Article CAS Google Scholar
  28. Chernomordik, L.V., Frolov, V.A., Leikina, E., Bronk, P. & Zimmerberg, J. The pathway of membrane fusion catalyzed by influenza hemagglutinin: restriction of lipids, hemifusion, and lipidic fusion pore formation. J. Cell Biol. 140, 1369–1382 (1998).
    Article CAS Google Scholar
  29. Mittal, A., Leikina, E., Chernomordik, L.V. & Bentz, J. Kinetically differentiating influenza hemagglutinin fusion and hemifusion machines. Biophys. J. 85, 1713–1724 (2003).
    Article CAS Google Scholar
  30. Poirier, M.A. et al. The synaptic SNARE complex is a parallel four-stranded helical bundle. Nat. Struct. Biol. 5, 765–769 (1998).
    Article CAS Google Scholar
  31. Sutton, R.B., Fasshauer, D., Jahn, R. & Brunger, A.T. Crystal structure of a SNARE complex involved in synaptic exocytosis at 2.4 Å resolution. Nature 395, 347–353 (1998).
    Article CAS Google Scholar
  32. Kweon, D.H., Kim, C.S. & Shin, Y.K. The membrane-dipped neuronal SNARE complex: a site-directed spin labeling electron paramagnetic resonance study. Biochemistry 41, 9264–9268 (2002).
    Article CAS Google Scholar
  33. Kweon, D.H., Kim, C.S. & Shin, Y.K. Insertion of the membrane-proximal region of the neuronal SNARE coiled coil into the membrane. J. Biol. Chem. 278, 12367–12373 (2003).
    Article CAS Google Scholar
  34. Tamm, L.K. Hypothesis: spring-loaded boomerang mechanism of influenza hemagglutinin-mediated membrane fusion. Biochim. Biophys. Acta 1614, 14–23 (2003).
    Article CAS Google Scholar
  35. Kweon, D.H., Kim, C.S. & Shin, Y.K. Regulation of neuronal SNARE assembly by the membrane. Nat. Struct. Biol. 10, 440–447 (2003).
    Article CAS Google Scholar
  36. Kweon, D.H. et al. Probing domain swapping for the neuronal SNARE complex with electron paramagnetic resonance. Biochemistry 41, 5449–5452 (2002).
    Article CAS Google Scholar

Download references