- Ahkter S, Richie CT, Zhang N, Behringer RR, Zhu C, Legerski RJ . (2005). Snm1-deficient mice exhibit accelerated tumorigenesis and susceptibility to infection. Mol Cell Biol 25: 10071–10078.
Article CAS Google Scholar
- Akhter S, Richie CT, Deng JM, Brey E, Zhang X, Patrick Jr C et al. (2004). Deficiency in SNM1 abolishes an early mitotic checkpoint induced by spindle stress. Mol Cell Biol 24: 10448–10455.
Article CAS Google Scholar
- Akkari YM, Bateman RL, Reifsteck CA, D'Andrea AD, Olson SB, Grompe M . (2001). The 4N cell cycle delay in Fanconi anemia reflects growth arrest in late S phase. Mol Genet Metab 74: 403–412.
Article CAS Google Scholar
- Andreassen PR, D'Andrea AD, Taniguchi T . (2004). ATR couples FANCD2 monoubiquitination to the DNA-damage response. Genes Dev 18: 1958–1963.
Article CAS Google Scholar
- Bakkenist CJ, Kastan MB . (2003). DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation. Nature 421: 499–506.
Article CAS Google Scholar
- Barber LJ, Ward TA, Hartley JA, McHugh PJ . (2005). DNA interstrand cross-link repair in the Saccharomyces cerevisiae cell cycle: overlapping roles for PSO2 (SNM1) with MutS factors and EXO1 during S phase. Mol Cell Biol 25: 2297–2309.
Article CAS Google Scholar
- Bartek J, Lukas C, Lukas J . (2004). Checking on DNA damage in S phase. Nat Rev Mol Cell Biol 5: 792–804.
Article CAS Google Scholar
- Callebaut I, Moshous D, Mornon JP, De Villartay JP . (2002). Metallo-beta-lactamase fold within nucleic acids processing enzymes: the beta-CASP family. Nucleic Acids Res 30: 3592–3601.
Article CAS Google Scholar
- Chan DW, Chen BP, Prithivirajsingh S, Kurimasa A, Story MD, Qin J et al. (2002). Autophosphorylation of the DNA-dependent protein kinase catalytic subunit is required for rejoining of DNA double-strand breaks. Genes Dev 16: 2333–2338.
Article CAS Google Scholar
- Chaturvedi P, Sudakin V, Bobiak ML, Fisher PW, Mattern MR, Jablonski S et al. (2002). Chfr regulates a mitotic stress pathway through its RING-finger domain with ubiquitin ligase activity. Cancer Res 62: 1797–1801.
CAS Google Scholar
- Demuth I, Digweed M, Concannon P . (2004). Human SNM1B is required for normal cellular response to both DNA interstrand crosslink-inducing agents and ionizing radiation. Oncogene 23: 8611–8618.
Article CAS Google Scholar
- Dominski Z . (2007). Nucleases of the metallo-beta-lactamase family and their role in DNA and RNA metabolism. Crit Rev Biochem Mol Biol 42: 67–93.
Article CAS Google Scholar
- Dronkert ML, De Wit J, Boeve M, Vasconcelos ML, van Steeg H, Tan TL et al. (2000). Disruption of mouse SNM1 causes increased sensitivity to the DNA interstrand cross-linking agent mitomycin C. Mol Cell Biol 20: 4553–4561.
Article CAS Google Scholar
- Freibaum BD, Counter CM . (2006). hSnm1B is a novel telomere-associated protein. J Biol Chem 281: 15033–15036..
Article CAS Google Scholar
- Geng L, Zhang X, Zheng S, Legerski RJ . (2007). Artemis links ATM to G2/M checkpoint recovery via regulation of Cdk1-cyclin B. Mol Cell Bio 27: 2625–2635.
Article CAS Google Scholar
- Grossmann KF, Ward AM, Matkovic ME, Folias AE, Moses RE . (2001). S.cerevisiae has three pathways for DNA interstrand crosslink repair. Mutat Res 487: 73–83.
Article CAS Google Scholar
- Haase E, Riehl D, Mack M, Brendel M . (1989). Molecular cloning of SNM1, a yeast gene responsible for a specific step in the repair of cross-linked DNA. Mol Gen Genet 218: 64–71.
Article CAS Google Scholar
- Hanada K, Budzowska M, Modesti M, Maas A, Wyman C, Essers J et al. (2006). The structure-specific endonuclease Mus81-Eme1 promotes conversion of interstrand DNA crosslinks into double-strands breaks. EMBO J 25: 4921–4932.
Article CAS Google Scholar
- Henriques JA, Moustacchi E . (1980). Isolation and characterization of pso mutants sensitive to photo-addition of psoralen derivatives in Saccharomyces cerevisiae. Genetics 95: 273–288.
CAS Google Scholar
- Ho GP, Margossian S, Taniguchi T, D'Andrea AD . (2006). Phosphorylation of FANCD2 on two novel sites is required for mitomycin C resistance. Mol Cell Biol 26: 7005–7015.
Article CAS Google Scholar
- Interthal H, Heyer WD . (2000). MUS81 encodes a novel helix-hairpin-helix protein involved in the response to UV- and methylation-induced DNA damage in Saccharomyces cerevisiae. Mol Gen Genet 263: 812–827.
Article CAS Google Scholar
- Ishiai M, Kimura M, Namikoshi K, Yamazoe M, Yamamoto K, Arakawa H et al. (2004). DNA cross-link repair protein SNM1A interacts with PIAS1 in nuclear focus formation. Mol Cell Biol 24: 10733–10741.
Article CAS Google Scholar
- Lambert S, Carr AM . (2005). Checkpoint responses to replication fork barriers. Biochimie 87: 591–602.
Article CAS Google Scholar
- Lenain C, Bauwens S, Amiard S, Brunori M, Giraud-Panis MJ, Gilson E . (2006). The Apollo 5′ exonuclease functions together with TRF2 to protect telomeres from DNA repair. Curr Biol 16: 1303–1310.
Article CAS Google Scholar
- Li X, Hejna J, Moses RE . (2005). The yeast Snm1 protein is a DNA 5′-exonuclease. DNA Repair (Amst) 4: 163–170.
Article CAS Google Scholar
- Li X, Moses RE . (2003). The beta-lactamase motif in Snm1 is required for repair of DNA double-strand breaks caused by interstrand crosslinks in S. cerevisiae. DNA Repair (Amst) 2: 121–129.
Article CAS Google Scholar
- Lukas J, Lukas C, Bartek J . (2004). Mammalian cell cycle checkpoints: signalling pathways and their organization in space and time. DNA Repair (Amst) 3: 997–1007.
Article CAS Google Scholar
- Ma Y, Pannicke U, Schwarz K, Lieber MR . (2002). Hairpin opening and overhang processing by an Artemis/DNA-dependent protein kinase complex in nonhomologous end joining and V(D)J recombination. Cell 108: 781–794.
Article CAS Google Scholar
- Magana-Schwencke N, Henriques JA, Chanet R, Moustacchi E . (1982). The fate of 8-methoxypsoralen photoinduced crosslinks in nuclear and mitochondrial yeast DNA: comparison of wild-type and repair-deficient strains. Proc Natl Acad Sci USA 79: 1722–1726.
Article CAS Google Scholar
- Matsusaka T, Pines J . (2004). Chfr acts with the p38 stress kinases to block entry to mitosis in mammalian cells. J Cell Biol 166: 507–516.
Article CAS Google Scholar
- McPherson JP, Lemmers B, Chahwan R, Pamidi A, Migon E, Matysiak-Zablocki E et al. (2004). Involvement of mammalian Mus81 in genome integrity and tumor suppression. Science 304: 1822–1826.
Article CAS Google Scholar
- Mladenov E, Tsaneva I, Anachkova B . (2007). Activation of the S phase DNA damage checkpoint by mitomycin C. J Cell Physiol 211: 468–476.
Article CAS Google Scholar
- Moshous D, Callebaut I, De Chasseval R, Corneo B, Cavazzana-Calvo M, Le Deist F et al. (2001). Artemis, a novel DNA double-strand break repair/V(D)J recombination protein, is mutated in human severe combined immune deficiency. Cell 105: 177–186.
Article CAS Google Scholar
- Moshous D, Li L, Chasseval R, Philippe N, Jabado N, Cowan MJ et al. (2000). A new gene involved in DNA double-strand break repair and V(D)J recombination is located on human chromosome 10p. Hum Mol Genet 9: 583–588.
Article CAS Google Scholar
- Multani AS, Ozen M, Narayan S, Kumar V, Chandra J, McConkey DJ et al. (2000). Caspase-dependent apoptosis induced by telomere cleavage and TRF2 loss. Neoplasia 2: 339–345.
Article CAS Google Scholar
- Nakanishi K, Taniguchi T, Ranganathan V, New HV, Moreau LA, Stotsky M et al. (2002). Interaction of FANCD2 and NBS1 in the DNA damage response. Nat Cell Biol 4: 913–920.
Article CAS Google Scholar
- Nakanishi K, Yang YG, Pierce AJ, Taniguchi T, Digweed M, D'Andrea AD et al. (2005). Human Fanconi anemia monoubiquitination pathway promotes homologous DNA repair. Proc Natl Acad Sci USA 102: 1110–1115.
Article CAS Google Scholar
- Nojima K, Hochegger H, Saberi A, Fukushima T, Kikuchi K, Yoshimura M et al. (2005). Multiple repair pathways mediate tolerance to chemotherapeutic cross-linking agents in vertebrate cells. Cancer Res 65: 11704–11711.
Article CAS Google Scholar
- Painter RB, Young BR . (1980). Radiosensitivity in ataxia-telangiectasia: a new explanation. Proc Natl Acad Sci USA 77: 7315–7317.
Article CAS Google Scholar
- Pannicke U, Ma Y, Hopfner KP, Niewolik D, Lieber MR, Schwarz K . (2004). Functional and biochemical dissection of the structure-specific nuclease Artemis. EMBO J 23: 1987–1997.
Article CAS Google Scholar
- Pichierri P, Averbeck D, Rosselli F . (2002). DNA cross-link-dependent RAD50/MRE11/NBS1 subnuclear assembly requires the Fanconi anemia C protein. Hum Mol Genet 11: 2531–2546.
Article CAS Google Scholar
- Pichierri P, Rosselli F . (2004a). Fanconi anemia proteins and the s phase checkpoint. Cell Cycle 3: 698–700.
Article CAS Google Scholar
- Pichierri P, Rosselli F . (2004b). The DNA crosslink-induced S-phase checkpoint depends on ATR-CHK1 and ATR-NBS1-FANCD2 pathways. Embo J 23: 1178–1187.
Article CAS Google Scholar
- Riballo E, Kuhne M, Rief N, Doherty A, Smith GC, Recio MJ et al. (2004). A pathway of double-strand break rejoining dependent upon ATM, Artemis, and proteins locating to gamma-H2AX foci. Mol Cell 16: 715–724.
Article CAS Google Scholar
- Richie CT, Peterson C, Lu T, Hittelman WN, Carpenter PB, Legerski RJ . (2002). hSnm1 colocalizes and physically associates with 53BP1 before and after DNA damage. Mol Cell Biol 22: 8635–8647.
Article CAS Google Scholar
- Rooney S, Sekiguchi J, Whitlow S, Eckersdorff M, Manis JP, Lee C et al. (2004). Artemis and p53 cooperate to suppress oncogenic N-myc amplification in progenitor B cells. Proc Natl Acad Sci USA 101: 2410–2415.
Article CAS Google Scholar
- Rooney S, Sekiguchi J, Zhu C, Cheng HL, Manis J, Whitlow S et al. (2002). Leaky SCID phenotype associated with defective V(D)J coding end processing in Artemis-deficient mice. Mol Cell 10: 1379–1390.
Article CAS Google Scholar
- Ruhland A, Kircher M, Wilborn F, Brendel M . (1981). A yeast mutant specifically sensitive to bifunctional alkylation. Mutat Res 91: 457–462.
Article CAS Google Scholar
- Sala-Trepat M, Rouillard D, Escarceller M, Laquerbe A, Moustacchi E, Papadopoulo D . (2000). Arrest of S-phase progression is impaired in Fanconi anemia cells. Exp Cell Res 260: 208–215.
Article CAS Google Scholar
- Scolnick DM, Halazonetis TD . (2000). Chfr defines a mitotic stress checkpoint that delays entry into metaphase. Nature 406: 430–435.
Article CAS Google Scholar
- Seyschab H, Friedl R, Sun Y, Schindler D, Hoehn H, Hentze S et al. (1995). Comparative evaluation of diepoxybutane sensitivity and cell cycle blockage in the diagnosis of Fanconi anemia. Blood 85: 2233–2237.
CAS Google Scholar
- Shen X, Jun S, O'Neal LE, Sonoda E, Bemark M, Sale JE et al. (2006). REV3 and REV1 play major roles in recombination-independent repair of DNA interstrand cross-links mediated by monoubiquitinated proliferating cell nuclear antigen (PCNA). J Biol Chem 281: 13869–13872.
Article CAS Google Scholar
- Sobeck A, Stone S, Costanzo V, De Graaf B, Reuter T, De Winter J et al. (2006). Fanconi anemia proteins are required to prevent accumulation of replication-associated DNA double-strand breaks. Mol Cell Biol 26: 425–437.
Article CAS Google Scholar
- Stiff T, Reis C, Alderton GK, Woodbine L, O'Driscoll M, Jeggo PA . (2005). Nbs1 is required for ATR-dependent phosphorylation events. EMBO J 24: 199–208.
Article CAS Google Scholar
- Summers MK, Bothos J, Halazonetis TD . (2005). The CHFR mitotic checkpoint protein delays cell cycle progression by excluding Cyclin B1 from the nucleus. Oncogene 24: 2589–2598.
Article CAS Google Scholar
- Taniguchi T, Garcia-Higuera I, Xu B, Andreassen PR, Gregory RC, Kim ST et al. (2002). Convergence of the Fanconi anemia and ataxia telangiectasia signaling pathways. Cell 109: 459–472.
Article CAS Google Scholar
- Thompson LH, Hinz JM, Yamada NA, Jones NJ . (2005). How Fanconi anemia proteins promote the four Rs: replication, recombination, repair, and recovery. Environ Mol Mutagen 45: 128–142.
Article CAS Google Scholar
- van Overbeek M, De Lange T . (2006). Apollo, an Artemis-related nuclease, interacts with TRF2 and protects human telomeres in S phase. Curr Biol 16: 1295–1302.
Article CAS Google Scholar
- Wang J, Pluth JM, Cooper PK, Cowan MJ, Chen DJ, Yannone SM . (2005). Artemis deficiency confers a DNA double-strand break repair defect and Artemis phosphorylation status is altered by DNA damage and cell cycle progression. DNA Repair (Amst) 4: 556–570.
Article CAS Google Scholar
- Wang X, Peterson CA, Zheng H, Nairn RS, Legerski RJ, Li L . (2001). Involvement of nucleotide excision repair in a recombination-independent and error-prone pathway of DNA interstrand cross-link repair. Mol Cell Biol 21: 713–720.
Article CAS Google Scholar
- Wilborn F, Brendel M . (1989). Formation and stability of interstrand cross-links induced by cis- and trans-diamminedichloroplatinum (II) in the DNA of Saccharomyces cerevisiae strains differing in repair capacity. Curr Genet 16: 331–338.
Article CAS Google Scholar
- Xu B, Kim ST, Lim DS, Kastan MB . (2002). Two molecularly distinct G(2)/M checkpoints are induced by ionizing irradiation. Mol Cell Biol 22: 1049–1059.
Article CAS Google Scholar
- Yu X, Minter-Dykhouse K, Malureanu L, Zhao WM, Zhang D, Merkle CJ et al. (2005). Chfr is required for tumor suppression and Aurora A regulation. Nat Genet 37: 401–406.
Article CAS Google Scholar
- Zhang N, Kaur R, Lu X, Shen X, Li L, Legerski RJ . (2005). The Pso4 mRNA splicing and DNA repair complex interacts with WRN for processing of DNA interstrand cross-links. J Biol Chem 280: 40559–40567.
Article CAS Google Scholar
- Zhang N, Liu X, Li L, Legerski R . (2007). Double-strand breaks induce homologous recombinational repair of interstrand cross-links via cooperation of MSH2, ERCC1-XPF, REV3, and the Fanconi anemia pathway. DNA Repair (Amst) 6: 1670–1678.
Article CAS Google Scholar
- Zhang X, Succi J, Feng Z, Prithivirajsingh S, Story MD, Legerski RJ . (2004). Artemis is a phosphorylation target of ATM and ATR and is involved in the G2/M DNA damage checkpoint response. Mol Cell Biol 24: 9207–9220.
Article CAS Google Scholar
- Zheng H, Wang X, Legerski RJ, Glazer PM, Li L . (2006). Repair of DNA interstrand cross-links: interactions between homology-dependent and homology-independent pathways. DNA Repair (Amst) 5: 566–574.
Article CAS Google Scholar
- Zheng H, Wang X, Warren AJ, Legerski RJ, Nairn RS, Hamilton JW et al. (2003). Nucleotide excision repair- and polymerase eta-mediated error-prone removal of mitomycin C interstrand cross-links. Mol Cell Biol 23: 754–761.
Article CAS Google Scholar