Immune selection in neoplasia: towards a microevolutionary model of cancer development (original) (raw)
Ademmer K, Ebert M, Muller Ostermeyer F, Friess H, Buchler MW, Schubert W and Malfertheiner P (1998) Effector T lymphocyte subsets in human pancreatic cancer: detection of CD8(+) CD18(+) cells and CD8(+) CD103(+) cells by multi-epitope imaging. Clin Exp Immunol112: 21–26 ArticleCASPubMedPubMed Central Google Scholar
Agrawal B, Krantz MJ, Reddish MA and Longenecker BM (1998) Cancer-associated MUC1 mucin inhibits human T-cell proliferation, which is reversible by IL-2. Nat Med4: 43–49 ArticleCASPubMed Google Scholar
Aizawa K, Ueki K, Suzuki S, Yabusaki H, Kanda T, Nishimaki T, Suzuki T and Hatakeyama K (1999) Apoptosis and Bcl-2 expression in gastric carcinomas: Correlation with clinicopathological variables, p53 expression, cell proliferation and prognosis. International Journal of Oncology14: 85–91 CASPubMed Google Scholar
Alexandroff AB, Jackson AM, O’Donnell MA and James K (1999) BCG immunotherapy of bladder cancer: 20 years on. Lancet353: 1689–1694 ArticleCASPubMed Google Scholar
Bennett M, O’Connell J, O’Sullivan G, Roche D, Brady C, Kelly J, Collins J and Shanahan F (1999) Expression of Fas ligand by human gastric adenocarcinomas: a potential mechanism of immune escape in stomach cancer. Gut44: 156–162 ArticleCASPubMedPubMed Central Google Scholar
Boon T (1992) Toward a genetic analysis of tumor rejection antigens. Adv Cancer Res58: 177–210 ArticleCASPubMed Google Scholar
Cai ZZ, Bettaieb A, ElMahdani N, Legres LG, Stancou R, Masliah J and Chouaib S (1997) Alteration of the sphingomyelin/ceramide pathway is associated with resistance of human breast carcinoma MCF7 cells to tumor necrosis factor-alpha-mediated cytotoxicity. J Biol Chem272: 6918–6926 ArticleCASPubMed Google Scholar
Chen YT, Scanlan MJ, Sahin U, Tureci O, Gure AO, Tsang SL, Williamson B, Stockert E, Pfreundschuh M and Old LJ (1997) A testicular antigen aberrantly expressed in human cancers detected by autologous antibody screening. Proc Nat Acad Sci USA94: 1914–1918 ArticleCASPubMedPubMed Central Google Scholar
Cheng JH, Zhou T, Liu CD, Shapiro JP, Brauer MJ, Kiefer MC, Barr PJ and Mountz JD (1994) Protection from Fas-mediated apoptosis by a soluble form of the Fas molecule. Science263: 1759–1762 ArticleCASPubMed Google Scholar
Chouaib S, Asselin Paturel C, MamiChouaib F, Caignard A and Blay JY (1997) The host-tumor immune conflict: from immunosuppression to resistance and destruction. Immunol Today18: 493–497 ArticleCASPubMed Google Scholar
Christofori G and Semb H (1999) The role of the cell-adhesion molecule E-cadherin as a tumour-suppressor gene. Trends Biochem Sci24: 73–76 ArticleCASPubMed Google Scholar
Cox AL, Skipper J, Chen Y, Henderson RA, Darrow TL, Shabanowitz J, Engelhard VH, Hunt DF and Slingluff CL (1994) Identification of a peptide recognized by 5 melanoma-specific human cytotoxic T cell lines. Science264: 716–719 ArticleCASPubMed Google Scholar
Cromme FV, Vanbommel PFJ, Walboomers JMM, Gallee MPW, Stern PL, Kenemans P, Helmerhorst TJM, Stukart MJ and Meijer C (1994) Differences in MHC and TAP-1 expression in cervical cancer lymph node metastases as compared with the primary tumours. Br J Cancer69: 1176–1181 ArticleCASPubMedPubMed Central Google Scholar
Dawkins R (1988) The Blind Watchmaker Penguin: London Google Scholar
Driscoll J, Brown MG, Finley D and Monaco JJ (1993) MHC linked LMP gene products specifically alter peptidase activities of the proteasome. Nature365: 262–264 ArticleCASPubMed Google Scholar
Eder IE, Stenzl A, Hobisch A, Cronauer MV, Bartsch G and Klocker H (1997) Expression of transforming growth factors beta-1, beta 2 and beta 3 in human bladder carcinomas. Br J Cancer75: 1753–1760 ArticleCASPubMedPubMed Central Google Scholar
Engel AM, Svane IM, Rygaard J and Werdelin O (1997) MCA sarcomas induced in scid mice are more immunogenic than MCA sarcomas induced in congenic, immunocompetent mice. Scand J Immunol45: 463–470 ArticleCASPubMed Google Scholar
Fey MF and Tobler A (1996) Tumour heterogeneity and clonality – An old theme revisited. Ann Oncol7: 121–128 ArticleCASPubMed Google Scholar
Fuchs EJ and Matzinger P (1996) Is cancer dangerous to the immune system?. Semin Immunol8: 271–280 ArticleCASPubMed Google Scholar
Gallucci S, Lolkema M and Matzinger P (1999) Natural adjuvants: Endogenous activators of dendritic cells. Nat Med5: 1249–1255 ArticleCASPubMed Google Scholar
Garrido F, Cabrera T, Concha A, Glew S, Ruizcabello F and Stern PL (1993) Natural history of HLA expression during tumour development. Immunol Today14: 491–499 ArticleCASPubMed Google Scholar
Garrido F, Ruiz Cabello F, Cabrera T, Perez Villar JJ, Lopez Botet M, Duggan Keen M and Stern PL (1997) Implications for immunosurveillance of altered HLA class I phenotypes in human tumours. Immunol Today18: 89–95 ArticleCASPubMed Google Scholar
Gastl GA, Abrams JS, Nanus DM, Oosterkamp R, Silver J, Liu F, Chen M, Albino AP and Bander NH (1993) Interleukin-10 production by human carcinoma cell lines and its relationship to interleukin-6 expression. Int J Cancer55: 96–101 ArticleCASPubMed Google Scholar
Hahne M, Rimoldi D, Schroter M, Romero P, Schreier M, French LE, Schneider P, Bornand T, Fontana A, Lienard D, Cerottini JC and Tschopp J (1996) Melanoma cell expression of Fas(Apo-1/CD95) ligand: Implications for tumor immune escape. Science274: 1363–1366 ArticleCASPubMed Google Scholar
Hakansson L, Adell G, Boeryd B, Sjogren F and Sjodahl R (1997) Infiltration of mononuclear inflammatory cells into primary colorectal carcinomas: An immunohistological analysis. Br J Cancer75: 374–380 ArticleCASPubMedPubMed Central Google Scholar
Hu HM, Urba WJ and Fox BA (1998) Gene-modified tumor vaccine with therapeutic potential shifts tumor-specific T cell response from a type 2 to a type 1 cytokine profile. J Immunol161: 3033–3041 CASPubMed Google Scholar
Irmler M, Thome M, Hahne M, Schneider P, Hofmann B, Steiner V, Bodmer JL, Schroter M, Burns K, Mattmann C, Rimoldi D, French LE and Tschopp J (1997) Inhibition of death receptor signals by cellular FLIP. Nature388: 190–195 ArticleCASPubMed Google Scholar
Jackson AM, Alexandroff AB, Fleming D, Prescott S, Chisholm GD and James K (1994) Bacillus Calmette-Guerin (BCG) organisms directly alter the growth of bladder tumor cells. International Journal of Oncology5: 697–703 CASPubMed Google Scholar
Janeway CA, Goodnow CC and Medzhitov R (1996) Immunological tolerance – danger, pathogen on the premises. Curr Biol6: 519–522 ArticleCASPubMed Google Scholar
Jodo S, Kobayashi S, Nakajima Y, Matsunaga T, Nakayama N, Ogura N, Kayagaki N, Okumura K and Koike T (1998) Elevated serum levels of soluble Fas/APO-1 (CD95) in patients with hepatocellular carcinoma. Clin Exp Immunol112: 166–171 ArticleCASPubMedPubMed Central Google Scholar
Karecla PI, Green SJ, Bowden SJ, Coadwell J and Kilshaw PJ (1996) Identification of a binding site for integrin alpha E beta(7) in the N-terminal domain of E-cadherin. J Biol Chem271: 30909–30915 ArticleCASPubMed Google Scholar
Keating PJ, Cromme FV, Duggankeen M, Snijders PJF, Walboomers JMM, Hunter RD, Dyer PA and Stern PL (1995) Frequency of downregulation of individual HLA-A and HLA-B alleles in cervical carcinomas in relation to TAP-1 expression. Br J Cancer72: 405–411 ArticleCASPubMedPubMed Central Google Scholar
Kurokohchi K, Carrington M, Mann DL, Simonis TB, Alexander Miller MA, Feinstone SM, Akatsuka T and Berzofsky JA (1996) Expression of HLA class I molecules and the transporter associated with antigen processing in hepatocellular carcinoma. Hepatology23: 1181–1188 ArticleCASPubMed Google Scholar
Lee PP, Yee C, Savage PA, Fong L, Brockstedt D, Weber JS, Johnson D, Swetter S, Thompson J, Greenberg PD, Roederer M and Davis MM (1999) Characterization of circulating T cells specific for tumor-associated antigens in melanoma patients. Nat Med5: 677–685 ArticleCASPubMed Google Scholar
Lehmann F, Marchand M, Hainaut P, Pouillart P, Sastre X, Ikeda H, Boon T and Coulie PG (1995) Differences in the antigens recognized by cytolytic T cells on 2 successive mctastases of a melanoma patient are consistent with immune selection. Eur J Immunol25: 340–347 ArticleCASPubMed Google Scholar
Lengauer C, Kinzler KW and Vogelstein B (1998) Genetic instabilities in human cancers. Nature396: 643–649 ArticleCASPubMed Google Scholar
Ljunggren HG, Stam NJ, Ohlen C, Neefjes JJ, Hoglund P, Heemels MT, Bastin J, Schumacher TNM, Townsend A, Karre K and Ploegh HL (1990) Empty MHC class I molecules come out in the cold. Nature346: 476–480 ArticleCASPubMed Google Scholar
Maeda H and Shiraishi A (1996) TGF-beta contributes to the shift toward Th2-type responses through direct and IL-1O-mediated pathways in tumor-bearing mice. J Immunol156: 73–78 CASPubMed Google Scholar
Maeurer MJ, Gollin SM, Martin D, Swaney W, Bryant J, Castelli C, Robbins P, Parmiani G, Storkus WJ and Lotze MT (1996) Tumor escape from immune recognition – Lethal recurrent melanoma in a patient associated with downregulation of the peptide transporter protein TAP-1 and loss of expression of the immunodominant MART-1/Melan-A antigen. J Clin Invest98: 1633–1641 ArticleCASPubMedPubMed Central Google Scholar
Marzo AL, Lake RA, Lo D, Sherman L, McWilliam A, Nelson D, Robinson BWS and Scott B (1999) Tumor antigens are constitutively presented in the draining lymph nodes. J Immunol162: 5838–5845 CASPubMed Google Scholar
Matsuda M, Salazar F, Petersson M, Masucci G, Hansson J, Pisa P, Zhang QJ, Masucci MG and Kiessling R (1994) Interleukin-10 pretreatment protects target cells from tumor-specific and allo-specific cytotoxic T cells and downregulates HLA Class I expression. J Exp Med180: 2371–2376 ArticleCASPubMed Google Scholar
Medema JP, Toes REM, Scaffidi C, Zheng TS, Flavell RA, Melief CJM, Peter ME, Offringa R and Krammer PH (1997) Cleavage of FLICE (caspase-8) by granzyme B during cytotoxic T lymphocyte-induced apoptosis. Eur J Immunol27: 3492–3498 ArticleCASPubMed Google Scholar
Melcher A, Todryk S, Hardwick N, Ford M, Jacobson M and Vile RG (1998) Tumor immunogenicity is determined by the mechanism of cell death via induction of heat shock protein expression. Nat Med4: 581–587 ArticleCASPubMed Google Scholar
Morisaki T, Katano M, Ikubo A, Anan K, Nakamura M, Nakamura K, Sato H, Tanaka M and Torisu M (1996) Immunosuppressive cytokines (IL-10, TGF-beta) genes expression in human gastric carcinoma tissues. J Surg Oncol63: 234–239 ArticleCASPubMed Google Scholar
Multhoff G, Botzler C, Wiesnet M, Muller E, Meier T, Wilmanns W and Issels RD (1995) A stress inducible 72-Kda heat shock protein (Hsp72) is expressed on the surface of human tumour cells, but not on normal cells. Int J Cancer61: 272–279 ArticleCASPubMed Google Scholar
Niehans GA, Brunner T, Frizelle SP, Liston JC, Salerno CT, Knapp DJ, Green DR and Kratzke RA (1997) Human lung carcinomas express Fas ligand. Cancer Res57: 1007–1012 CASPubMed Google Scholar
Ochsenbein AF, Klenerman P, Karrer U, Ludewig B, Pericin M, Hengartner H and Zinkernagel RM (1999) Immune surveillance against a solid tumor fails because of immunological ignorance. Proc Natl Acad Sci USA96: 2233–2238 ArticleCASPubMedPubMed Central Google Scholar
O’Connell J, Bennett MW, O’Sullivan GC, Roche D, Kelly J, Collins JK and Shanahan F (1998) Fas ligand expression in primary colon adenocarcinomas: Evidence that the Fas counterattack is a prevalent mechanism of immune evasion in human colon cancer. J Pathol186: 240–246 ArticlePubMed Google Scholar
Pena JC, Thompson CB, Recant W, Vokes EE and Rudin CM (1999) Bcl-x(L) and Bcl-2 expression in squamous cell carcinoma of the head and neck. Cancer85: 164–170 ArticleCASPubMed Google Scholar
Pitti RM, Marsters SA, Lawrence DA, Roy M, Kischkel FC, Dowd P, Huang A, Donahue CJ, Sherwood SW, Baldwin DT, Godowski PJ, Wood WI, Gurney AL, Hillan KJ, Cohen RL, Goddard AD, Botstein D and Ashkenazi A (1998) Genomic amplification of a decoy receptor for Fas ligand in lung and colon cancer. Nature396: 699–703 ArticleCASPubMed Google Scholar
Poppas DP, Pavlovich CP, Folkman J, Voest EE, Chen XH, Luster AD and O’Donnell MA (1998) Intravesical bacille Calmette-Guerin induces the antiangiogenic chemokine interferon-inducible protein 10. Urology52: 268–275 ArticleCASPubMed Google Scholar
Restifo NP, Esquivel F, Kawakami Y, Yewdell JW, Mule JJ, Rosenberg SA and Bennink JR (1993) Identification of human cancers deficient in antigen processing. J Exp Med177: 265–272 ArticleCASPubMed Google Scholar
Romero P, Dunbar PR, Valmori D, Pittet M, Ogg GS, Rimoldi D, Chen JL, Lienard D, Cerottini JC and Cerundolo V (1998) Ex vivo staining of metastatic lymph nodes by class I major histocompatibility complex tetramers reveals high numbers of antigen-experienced tumor-specific cytolytic T lymphocytes. J Exp Med188: 1641–1650 ArticleCASPubMedPubMed Central Google Scholar
Rosenberg SA (1999) A new era for cancer immunotherapy based on the genes that encode cancer antigens. Immunity10: 281–287 ArticleCASPubMed Google Scholar
Sahin U, Tureci O, Schmitt H, Cochlovius B, Johannes T, Schmits R, Stenner F, Luo GR, Schobert I and Pfreundschuh M (1995) Human neoplasms elicit multiple specific immune responses in the autologous host. Proc Nat Acad Sci USA92: 11810–11813 ArticleCASPubMedPubMed Central Google Scholar
Seliger B, Hohne A, Knuth A, Bernhard H, Ehring B, Tampe R and Huber C 1996 a) Reduced membrane major histocompatibility complex class I density and stability in a subset of human renal cell carcinomas with low TAP and LMP expression. Clinical Cancer Research2: 1427–1433 CASPubMed Google Scholar
Seliger B, Hohne A, Knuth A, Bernhard H, Meyer T, Tampe R, Momburg F and Huber C 1996 b) Analysis of the major histocompatibility complex class I antigen presentation machinery in normal and malignant renal cells: Evidence for deficiencies associated with transformation and progression. Cancer Res56: 1756–1760 CASPubMed Google Scholar
Seliger B, Maeurer MJ and Ferrone S (1997) TAP off – Tumors on. Immunol Today18: 292–299 CASPubMed Google Scholar
Strand S, Hofmann WJ, Hug H, Muller M, Otto G, Strand D, Mariani SM, Stremmel W, Krammer PH and Galle PR (1996) Lymphocyte apoptosis induced by CD95 (Apo-1/Fas) ligand expressing tumor cells – a mechanism of immune evasion. Nat Med2: 1361–1366 ArticleCASPubMed Google Scholar
Svane IM, Engel AM, Nielsen MB, Ljunggren HG, Rygaard J and Werdelin O (1996) Chemically induced sarcomas from nude mice are more immunogenic than similar sarcomas from congenic normal mice. Eur J Immunol26: 1844–1850 ArticleCASPubMed Google Scholar
Taylor Papadimitriou J and Finn OJ (1997) Biology, biochemistry and immunology of carcinoma-associated mucins. Immunol Today18: 105–107 ArticleCASPubMed Google Scholar
Todryk S, Melcher AA, Hardwick N, Linardakis E, Bateman A, Colombo MP, Stoppacciaro A and Vile RG (1999) Heat shock protein 70 induced during tumor cell killing induces Th1 cytokines and targets immature dendritic cell precursors to enhance antigen uptake. J Immunol163: 1398–1408 CASPubMed Google Scholar
Torzewski M, Sarbia M, Heep H, Dutkowski P, Willers R and Gabbert HE (1998) Expression of Bcl-X-L, an antiapoptotic member of the Bcl-2 family, in esophageal squamous cell carcinoma. Clinical Cancer Research4: 577–583 CASPubMed Google Scholar
van de Welvankemenade E, Ligtenberg MJL, de Boer AJ, Buijs F, Vos HL, Melief CJM, Hilkens J and Figdor CG (1993) Episialin (MUC1) inhibits cytotoxic lymphocyte-target cell interaction. J Immunol151: 767–776 Google Scholar
Vanky F, Nagy N, Hising C, Sjovall K, Larson B and Klein E (1997) Human ex vivo carcinoma cells produce transforming growth factor beta and thereby can inhibit lymphocyte functions in vitro. Cancer Immunol Immunother43: 317–323 ArticleCASPubMed Google Scholar
Wick M, Dubey P, Koeppen H, Siegel CT, Fields PE, Chen LP, Bluestone JA and Schreiber H (1997) Antigenic cancer cells grow progressively in immune hosts without evidence for T cell exhaustion or systemic anergy. J Exp Med186: 229–238 ArticleCASPubMedPubMed Central Google Scholar
Yannelli JR, Hyatt C, McConnell S, Hines K, Jacknin L, Parker L, Sanders M and Rosenberg SA (1996) Growth of tumor-infiltrating lymphocytes from human solid cancers: Summary of a 5-year experience. Int J Cancer65: 413–421 ArticleCASPubMed Google Scholar
York IA and Rock KL (1996) Antigen processing and presentation by the class I major histocompatibility complex. Annu Rev Immunol14: 369–396 ArticleCASPubMed Google Scholar
Young DC (1989) Drug resistance: the clinical problem. Drug Resistance in Cancer Therapy Ozols RF (eds, pp 1–26, Kluwer: Dordrecht Google Scholar
Zhang K, Sikut R and Hansson GC (1997) A MUC1 mucin secreted from a colon carcinoma cell line inhibits target cell lysis by natural killer cells. Cell Immunol176: 158–165 ArticleCASPubMed Google Scholar