Ali Gamal - Academia.edu (original) (raw)

Papers by Ali Gamal

Research paper thumbnail of Anthraquinones from Galium sinaicum

Phytochemistry, 1995

The new anthraquinones, 7-methylanthragallol 1,3-dimethyl ether, 7-methyl-anthragaUol 2-methyl et... more The new anthraquinones, 7-methylanthragallol 1,3-dimethyl ether, 7-methyl-anthragaUol 2-methyl ether, 6-methylanthragallol 3-methyl ether, 8-hydroxyanthragallol 2,3-dimethyl ether, 7-formylanthragallol 1,3-dimethyl ether, copareolatin 5,7-dimethyl ether, copareolatin 6,7-dimethyl ether, 6-methoxylucidin to-ethyl ether and 6-hydroxyxanthopurpurin, as well as a novel bianthraquinone, bisinaiquinone [10,2'-bi(9-hydroxy-3-methyl-l,4-anthraquinonyl)] were isolated from the roots of Galium sinaicum. Their structures were established by spectroscopic techniques including 2D-NMR. In addition, eight known anthraquinones were also isolated and fully characterized.

Research paper thumbnail of Anthraquinones from the polar fractions of Galium sinaicum

Phytochemistry, 1996

The new anthraquinones, 6,7-dimethoxy xanthopurpurin, 6-hydroxy-7-methoxy rubiadin, 5-hydroxy-6hy... more The new anthraquinones, 6,7-dimethoxy xanthopurpurin, 6-hydroxy-7-methoxy rubiadin, 5-hydroxy-6hydroxymethyl anthragallol 1,3-dimethyl ether, 7-carboxy anthragallol 1,3-dimethyl ether, anthragallol l-methyl ether 3-O-fl-D-glucopyranoside, anthragallol l-methyl ether 3-O-rutinoside, anthragallol 3-O-rutinoside and alizarin 1-methyl ether 2-O-primeveroside were isolated from the CH2CI 2 and n-BuOH extracts of Galium sinaicum roots and their structures were established by various spectroscopic techniques. In addition, two known anthraquinones were also isolated and fully characterized.

Research paper thumbnail of Studies on the chemical constituents of Atraphaxis spinosa L. var. sinaica Boiss

Natural Medicines, 1994

From an ethereal extract of Atraphaxis ginosa L. var. sinaica Borss. (Polygonaceae) , nine compou... more From an ethereal extract of Atraphaxis ginosa L. var. sinaica Borss. (Polygonaceae) , nine compounds were isolated and identified asN-trans-p-coumaroyl-3', 4'-dihydroxyphenylethylamine (1), Ntrans-f.eruloyl-3',4'-dihydroxyphenylethylamine (2), (-)-fisetinidol (B), (-)-catechin (4),butin (5), quercetin (6), quercetin-3-methvl ether (?),5-deoxykaempferol (8) and B-sitosterol glucoside (9).

Research paper thumbnail of Lignan bis-glucosides from Galium sinaicum

Research paper thumbnail of Flavonol Glycosides From Galium Sinaicum

…, 1999

D The flavonoid glycosides kaempferol 3-O-p-D-glucoside (l), kaemplerol 3'O-B'D'xylopyranosyl (1'... more D The flavonoid glycosides kaempferol 3-O-p-D-glucoside (l), kaemplerol 3'O-B'D'xylopyranosyl (1' -->2) O-p-D-glucopyranoside (ll), kaempf erol 3-O-[2-O-p-D-xylopyranosyl-6-O-u-L-rhamnopyranosyll p-D-glucopyranoside (lll), quercetin 3-O-p-D-glucopyranoside (lV), quercetin 3-O-<r-rhamnopyranosyl(1--->6)-p-D-glucopyranoside (V), quercetin 3-O-[2-O-p-D-xylopyranosyl-6-O-u-L-rhamnopyranosyll-p-D-glucopyranoside (Vl) were isolated from n-butanol extract ol the aerial parts of Galium sina' icum in addition to 7-carboxy-anthragallol-1 ,3-dimethyl ether (Vll) and vomifoliol (Vlll). The structures ol these compounds were established by various spectroscopic iechniques. Compounds lll and Vl were isolated for the first time from a Rubiaceous species while for ll and Vlll, this study represents the f irst report in the genus Galium. Keyphrases d Gatium sinaicum, Rubiaceae, aerial parts, llavonol glycosides, vomiloliol, anthragallol.

Research paper thumbnail of PART I Introduction to Algae and Their Importance 1 Biological Importance of Marine Algae 3

Research paper thumbnail of Umbellactal (I), a Novel Diterpenoid from the Formosan Soft Coral Xenia umbellata

Research paper thumbnail of ChemInform Abstract: Socotroside, a New Pentacyclic Cucurbitane Glycoside from Dendrosicyos socotrana

Research paper thumbnail of ChemInform Abstract: Sesquiterpene Lactones from Smyrnium olusatrum (I)-(III)

Research paper thumbnail of Dendrocyin: An Isocucurbitacin with Novel Cyclic Side Chain from Dendrosicyos socotrana

ChemInform, 2005

2005 Terpenes U 0200 Dendrocyin: An Isocucurbitacin with Novel Cyclic Side Chain from Dendrosicyo... more 2005 Terpenes U 0200 Dendrocyin: An Isocucurbitacin with Novel Cyclic Side Chain from Dendrosicyos socotrana. -One new compound (I) together with one known compound is isolated from the title plants' stems. -(HUSSEIN*, H. A.; ABDEL-HALIM, O. B.; MARWAN, E.-S. M.; EL-GAMAL, A. A.; MOSANA, R.; Phytochemistry 65 (2004) 18, 2551-2556; Dep. Pharmacogn., Fac. Pharm., Mansoura Univ., Mansoura 35516, Egypt; Eng.) -C. Oppel

Research paper thumbnail of Xenibellal, a novel norditerpenoid from the Formosan soft coral Xenia umbellata

Tetrahedron Letters, 2005

Xenibellal, isolated from the soft coral Xenia umbellata, is an unprecedented norditerpenoid. The... more Xenibellal, isolated from the soft coral Xenia umbellata, is an unprecedented norditerpenoid. The structure of xenibellal was established by extensive analysis of spectroscopic data.

Research paper thumbnail of Vibsanin O, a novel diterpenoid from Viburnum awabuki

Tetrahedron Letters, 2003

Vibsanin O, isolated from the leaves and twigs of Viburnum awabuki, is an unprecedented bicyclic ... more Vibsanin O, isolated from the leaves and twigs of Viburnum awabuki, is an unprecedented bicyclic diterpenoid. The structures of vibsanin O was established by extensive analysis of spectroscopic data.

Research paper thumbnail of Biological importance of marine algae

Saudi Pharmaceutical Journal, 2010

Marine organisms are potentially prolific sources of highly bioactive secondary metabolites that ... more Marine organisms are potentially prolific sources of highly bioactive secondary metabolites that might represent useful leads in the development of new pharmaceutical agents. Algae can be classified into two main groups; first one is the microalgae, which includes blue green algae, dinoflagellates, bacillariophyta (diatoms). . . etc., and second one is macroalgae (seaweeds) which includes green, brown and red algae. The microalgae phyla have been recognized to provide chemical and pharmacological novelty and diversity. Moreover, microalgae are considered as the actual producers of some highly bioactive compounds found in marine resources. Red algae are considered as the most important source of many biologically active metabolites in comparison to other algal classes. Seaweeds are used for great number of application by man. The principal use of seaweeds as a source of human food and as a source of gums (phycocollides). Phycocolloides like agar agar, alginic acid and carrageenan are primarily constituents of brown and red algal cell walls and are widely used in industry.

Research paper thumbnail of Anthraquinones from the polar fractions of Galium sinaicum

Phytochemistry, 1996

The new anthraquinones, 6,7-dimethoxy xanthopurpurin, 6-hydroxy-7-methoxy rubiadin, 5-hydroxy-6hy... more The new anthraquinones, 6,7-dimethoxy xanthopurpurin, 6-hydroxy-7-methoxy rubiadin, 5-hydroxy-6hydroxymethyl anthragallol 1,3-dimethyl ether, 7-carboxy anthragallol 1,3-dimethyl ether, anthragallol l-methyl ether 3-O-fl-D-glucopyranoside, anthragallol l-methyl ether 3-O-rutinoside, anthragallol 3-O-rutinoside and alizarin 1-methyl ether 2-O-primeveroside were isolated from the CH2CI 2 and n-BuOH extracts of Galium sinaicum roots and their structures were established by various spectroscopic techniques. In addition, two known anthraquinones were also isolated and fully characterized.

Research paper thumbnail of Anthraquinones from Galium sinaicum

Phytochemistry, 1995

The new anthraquinones, 7-methylanthragallol 1,3-dimethyl ether, 7-methyl-anthragaUol 2-methyl et... more The new anthraquinones, 7-methylanthragallol 1,3-dimethyl ether, 7-methyl-anthragaUol 2-methyl ether, 6-methylanthragallol 3-methyl ether, 8-hydroxyanthragallol 2,3-dimethyl ether, 7-formylanthragallol 1,3-dimethyl ether, copareolatin 5,7-dimethyl ether, copareolatin 6,7-dimethyl ether, 6-methoxylucidin to-ethyl ether and 6-hydroxyxanthopurpurin, as well as a novel bianthraquinone, bisinaiquinone [10,2'-bi(9-hydroxy-3-methyl-l,4-anthraquinonyl)] were isolated from the roots of Galium sinaicum. Their structures were established by spectroscopic techniques including 2D-NMR. In addition, eight known anthraquinones were also isolated and fully characterized.

Research paper thumbnail of Xenibellols A and B, New Diterpenoids from the Formosan Soft Coral Xenia u mbellata

Organic Letters, 2005

Xenibellols A (1) and B (2), possessing an unprecedented diterpenoid skeleton, were isolated from... more Xenibellols A (1) and B (2), possessing an unprecedented diterpenoid skeleton, were isolated from the soft coral Xenia umbellata. The structures of xenibellols A and B were established by extensive analysis of spectroscopic data.

Research paper thumbnail of Cytotoxic lupane-, secolupane-, and oleanane-type triterpenes from Viburnum awabuki

Natural Product Research, 2008

Research paper thumbnail of New Nardosinanes and 19-Oxygenated Ergosterols from the Soft Coral Nephthea a rmata Collected in Taiwan

Journal of Natural Products, 2004

Five new nardosinane sesquiterpenoids, armatins A-E, lemnal-1(10)-ene-2,12-dione (a new natural p... more Five new nardosinane sesquiterpenoids, armatins A-E, lemnal-1(10)-ene-2,12-dione (a new natural product), and two new cytotoxic 19-oxygenated ergosterols, armatinols A and B, were isolated from the methylene chloride extract of the soft coral Nephthea armata, collected in Taiwan. The structures were elucidated by 1D and 2D NMR spectral analysis, and their cytotoxicity was determined against selected cancer cells.

Research paper thumbnail of Steroids and Sesquiterpenoids from the Soft Corals Dendronephthya g igantea and Lemnalia c ervicorni

Journal of Natural Products, 2004

One new cytotoxic steroid, dendronesterone A (1), two new steroids, dendronesterones B and C (2 a... more One new cytotoxic steroid, dendronesterone A (1), two new steroids, dendronesterones B and C (2 and 3), and a known steroid (4) were isolated from the methylene chloride solubles of the Formosan soft coral Dendronephthya gigantea. Two cytotoxic ylangene-type sesquiterpenoids, lemnalol (5) and the new compound cervicol (6), as well as two ylangene-type sesquiterpenoids, isolemnalol (7) (a new compound) and 4-oxo-alpha-ylangene (8), were isolated from the methylene chloride solubles of the Formosan soft coral Lemnalia cervicorni. Their structures were elucidated by 1D and 2D NMR spectral analysis, and their cytotoxicity against selected cancer cells was measured in vitro.

Research paper thumbnail of New Cadinene Sesquiterpenoids from the Formosan Soft Coral Xenia p uerto-galerae

Journal of Natural Products, 2002

Six new cadinene sesquiterpenoids, xenitorins A-F (1-6), were isolated from the methylene chlorid... more Six new cadinene sesquiterpenoids, xenitorins A-F (1-6), were isolated from the methylene chloride solubles of the Formosan soft coral Xenia puerto-galerae. The structures were elucidated by 1D and 2D NMR spectral analysis, and their cytotoxicity against selected cancer cells was measured in vitro.

Research paper thumbnail of Anthraquinones from Galium sinaicum

Phytochemistry, 1995

The new anthraquinones, 7-methylanthragallol 1,3-dimethyl ether, 7-methyl-anthragaUol 2-methyl et... more The new anthraquinones, 7-methylanthragallol 1,3-dimethyl ether, 7-methyl-anthragaUol 2-methyl ether, 6-methylanthragallol 3-methyl ether, 8-hydroxyanthragallol 2,3-dimethyl ether, 7-formylanthragallol 1,3-dimethyl ether, copareolatin 5,7-dimethyl ether, copareolatin 6,7-dimethyl ether, 6-methoxylucidin to-ethyl ether and 6-hydroxyxanthopurpurin, as well as a novel bianthraquinone, bisinaiquinone [10,2'-bi(9-hydroxy-3-methyl-l,4-anthraquinonyl)] were isolated from the roots of Galium sinaicum. Their structures were established by spectroscopic techniques including 2D-NMR. In addition, eight known anthraquinones were also isolated and fully characterized.

Research paper thumbnail of Anthraquinones from the polar fractions of Galium sinaicum

Phytochemistry, 1996

The new anthraquinones, 6,7-dimethoxy xanthopurpurin, 6-hydroxy-7-methoxy rubiadin, 5-hydroxy-6hy... more The new anthraquinones, 6,7-dimethoxy xanthopurpurin, 6-hydroxy-7-methoxy rubiadin, 5-hydroxy-6hydroxymethyl anthragallol 1,3-dimethyl ether, 7-carboxy anthragallol 1,3-dimethyl ether, anthragallol l-methyl ether 3-O-fl-D-glucopyranoside, anthragallol l-methyl ether 3-O-rutinoside, anthragallol 3-O-rutinoside and alizarin 1-methyl ether 2-O-primeveroside were isolated from the CH2CI 2 and n-BuOH extracts of Galium sinaicum roots and their structures were established by various spectroscopic techniques. In addition, two known anthraquinones were also isolated and fully characterized.

Research paper thumbnail of Studies on the chemical constituents of Atraphaxis spinosa L. var. sinaica Boiss

Natural Medicines, 1994

From an ethereal extract of Atraphaxis ginosa L. var. sinaica Borss. (Polygonaceae) , nine compou... more From an ethereal extract of Atraphaxis ginosa L. var. sinaica Borss. (Polygonaceae) , nine compounds were isolated and identified asN-trans-p-coumaroyl-3', 4'-dihydroxyphenylethylamine (1), Ntrans-f.eruloyl-3',4'-dihydroxyphenylethylamine (2), (-)-fisetinidol (B), (-)-catechin (4),butin (5), quercetin (6), quercetin-3-methvl ether (?),5-deoxykaempferol (8) and B-sitosterol glucoside (9).

Research paper thumbnail of Lignan bis-glucosides from Galium sinaicum

Research paper thumbnail of Flavonol Glycosides From Galium Sinaicum

…, 1999

D The flavonoid glycosides kaempferol 3-O-p-D-glucoside (l), kaemplerol 3'O-B'D'xylopyranosyl (1'... more D The flavonoid glycosides kaempferol 3-O-p-D-glucoside (l), kaemplerol 3'O-B'D'xylopyranosyl (1' -->2) O-p-D-glucopyranoside (ll), kaempf erol 3-O-[2-O-p-D-xylopyranosyl-6-O-u-L-rhamnopyranosyll p-D-glucopyranoside (lll), quercetin 3-O-p-D-glucopyranoside (lV), quercetin 3-O-<r-rhamnopyranosyl(1--->6)-p-D-glucopyranoside (V), quercetin 3-O-[2-O-p-D-xylopyranosyl-6-O-u-L-rhamnopyranosyll-p-D-glucopyranoside (Vl) were isolated from n-butanol extract ol the aerial parts of Galium sina' icum in addition to 7-carboxy-anthragallol-1 ,3-dimethyl ether (Vll) and vomifoliol (Vlll). The structures ol these compounds were established by various spectroscopic iechniques. Compounds lll and Vl were isolated for the first time from a Rubiaceous species while for ll and Vlll, this study represents the f irst report in the genus Galium. Keyphrases d Gatium sinaicum, Rubiaceae, aerial parts, llavonol glycosides, vomiloliol, anthragallol.

Research paper thumbnail of PART I Introduction to Algae and Their Importance 1 Biological Importance of Marine Algae 3

Research paper thumbnail of Umbellactal (I), a Novel Diterpenoid from the Formosan Soft Coral Xenia umbellata

Research paper thumbnail of ChemInform Abstract: Socotroside, a New Pentacyclic Cucurbitane Glycoside from Dendrosicyos socotrana

Research paper thumbnail of ChemInform Abstract: Sesquiterpene Lactones from Smyrnium olusatrum (I)-(III)

Research paper thumbnail of Dendrocyin: An Isocucurbitacin with Novel Cyclic Side Chain from Dendrosicyos socotrana

ChemInform, 2005

2005 Terpenes U 0200 Dendrocyin: An Isocucurbitacin with Novel Cyclic Side Chain from Dendrosicyo... more 2005 Terpenes U 0200 Dendrocyin: An Isocucurbitacin with Novel Cyclic Side Chain from Dendrosicyos socotrana. -One new compound (I) together with one known compound is isolated from the title plants' stems. -(HUSSEIN*, H. A.; ABDEL-HALIM, O. B.; MARWAN, E.-S. M.; EL-GAMAL, A. A.; MOSANA, R.; Phytochemistry 65 (2004) 18, 2551-2556; Dep. Pharmacogn., Fac. Pharm., Mansoura Univ., Mansoura 35516, Egypt; Eng.) -C. Oppel

Research paper thumbnail of Xenibellal, a novel norditerpenoid from the Formosan soft coral Xenia umbellata

Tetrahedron Letters, 2005

Xenibellal, isolated from the soft coral Xenia umbellata, is an unprecedented norditerpenoid. The... more Xenibellal, isolated from the soft coral Xenia umbellata, is an unprecedented norditerpenoid. The structure of xenibellal was established by extensive analysis of spectroscopic data.

Research paper thumbnail of Vibsanin O, a novel diterpenoid from Viburnum awabuki

Tetrahedron Letters, 2003

Vibsanin O, isolated from the leaves and twigs of Viburnum awabuki, is an unprecedented bicyclic ... more Vibsanin O, isolated from the leaves and twigs of Viburnum awabuki, is an unprecedented bicyclic diterpenoid. The structures of vibsanin O was established by extensive analysis of spectroscopic data.

Research paper thumbnail of Biological importance of marine algae

Saudi Pharmaceutical Journal, 2010

Marine organisms are potentially prolific sources of highly bioactive secondary metabolites that ... more Marine organisms are potentially prolific sources of highly bioactive secondary metabolites that might represent useful leads in the development of new pharmaceutical agents. Algae can be classified into two main groups; first one is the microalgae, which includes blue green algae, dinoflagellates, bacillariophyta (diatoms). . . etc., and second one is macroalgae (seaweeds) which includes green, brown and red algae. The microalgae phyla have been recognized to provide chemical and pharmacological novelty and diversity. Moreover, microalgae are considered as the actual producers of some highly bioactive compounds found in marine resources. Red algae are considered as the most important source of many biologically active metabolites in comparison to other algal classes. Seaweeds are used for great number of application by man. The principal use of seaweeds as a source of human food and as a source of gums (phycocollides). Phycocolloides like agar agar, alginic acid and carrageenan are primarily constituents of brown and red algal cell walls and are widely used in industry.

Research paper thumbnail of Anthraquinones from the polar fractions of Galium sinaicum

Phytochemistry, 1996

The new anthraquinones, 6,7-dimethoxy xanthopurpurin, 6-hydroxy-7-methoxy rubiadin, 5-hydroxy-6hy... more The new anthraquinones, 6,7-dimethoxy xanthopurpurin, 6-hydroxy-7-methoxy rubiadin, 5-hydroxy-6hydroxymethyl anthragallol 1,3-dimethyl ether, 7-carboxy anthragallol 1,3-dimethyl ether, anthragallol l-methyl ether 3-O-fl-D-glucopyranoside, anthragallol l-methyl ether 3-O-rutinoside, anthragallol 3-O-rutinoside and alizarin 1-methyl ether 2-O-primeveroside were isolated from the CH2CI 2 and n-BuOH extracts of Galium sinaicum roots and their structures were established by various spectroscopic techniques. In addition, two known anthraquinones were also isolated and fully characterized.

Research paper thumbnail of Anthraquinones from Galium sinaicum

Phytochemistry, 1995

The new anthraquinones, 7-methylanthragallol 1,3-dimethyl ether, 7-methyl-anthragaUol 2-methyl et... more The new anthraquinones, 7-methylanthragallol 1,3-dimethyl ether, 7-methyl-anthragaUol 2-methyl ether, 6-methylanthragallol 3-methyl ether, 8-hydroxyanthragallol 2,3-dimethyl ether, 7-formylanthragallol 1,3-dimethyl ether, copareolatin 5,7-dimethyl ether, copareolatin 6,7-dimethyl ether, 6-methoxylucidin to-ethyl ether and 6-hydroxyxanthopurpurin, as well as a novel bianthraquinone, bisinaiquinone [10,2'-bi(9-hydroxy-3-methyl-l,4-anthraquinonyl)] were isolated from the roots of Galium sinaicum. Their structures were established by spectroscopic techniques including 2D-NMR. In addition, eight known anthraquinones were also isolated and fully characterized.

Research paper thumbnail of Xenibellols A and B, New Diterpenoids from the Formosan Soft Coral Xenia u mbellata

Organic Letters, 2005

Xenibellols A (1) and B (2), possessing an unprecedented diterpenoid skeleton, were isolated from... more Xenibellols A (1) and B (2), possessing an unprecedented diterpenoid skeleton, were isolated from the soft coral Xenia umbellata. The structures of xenibellols A and B were established by extensive analysis of spectroscopic data.

Research paper thumbnail of Cytotoxic lupane-, secolupane-, and oleanane-type triterpenes from Viburnum awabuki

Natural Product Research, 2008

Research paper thumbnail of New Nardosinanes and 19-Oxygenated Ergosterols from the Soft Coral Nephthea a rmata Collected in Taiwan

Journal of Natural Products, 2004

Five new nardosinane sesquiterpenoids, armatins A-E, lemnal-1(10)-ene-2,12-dione (a new natural p... more Five new nardosinane sesquiterpenoids, armatins A-E, lemnal-1(10)-ene-2,12-dione (a new natural product), and two new cytotoxic 19-oxygenated ergosterols, armatinols A and B, were isolated from the methylene chloride extract of the soft coral Nephthea armata, collected in Taiwan. The structures were elucidated by 1D and 2D NMR spectral analysis, and their cytotoxicity was determined against selected cancer cells.

Research paper thumbnail of Steroids and Sesquiterpenoids from the Soft Corals Dendronephthya g igantea and Lemnalia c ervicorni

Journal of Natural Products, 2004

One new cytotoxic steroid, dendronesterone A (1), two new steroids, dendronesterones B and C (2 a... more One new cytotoxic steroid, dendronesterone A (1), two new steroids, dendronesterones B and C (2 and 3), and a known steroid (4) were isolated from the methylene chloride solubles of the Formosan soft coral Dendronephthya gigantea. Two cytotoxic ylangene-type sesquiterpenoids, lemnalol (5) and the new compound cervicol (6), as well as two ylangene-type sesquiterpenoids, isolemnalol (7) (a new compound) and 4-oxo-alpha-ylangene (8), were isolated from the methylene chloride solubles of the Formosan soft coral Lemnalia cervicorni. Their structures were elucidated by 1D and 2D NMR spectral analysis, and their cytotoxicity against selected cancer cells was measured in vitro.

Research paper thumbnail of New Cadinene Sesquiterpenoids from the Formosan Soft Coral Xenia p uerto-galerae

Journal of Natural Products, 2002

Six new cadinene sesquiterpenoids, xenitorins A-F (1-6), were isolated from the methylene chlorid... more Six new cadinene sesquiterpenoids, xenitorins A-F (1-6), were isolated from the methylene chloride solubles of the Formosan soft coral Xenia puerto-galerae. The structures were elucidated by 1D and 2D NMR spectral analysis, and their cytotoxicity against selected cancer cells was measured in vitro.