Christian Jimenez - Academia.edu (original) (raw)

Papers by Christian Jimenez

The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association, 2021

OBJECTIVE This study compares patients undergoing early cleft lip repair (ECLR) (<3-months) an... more OBJECTIVE This study compares patients undergoing early cleft lip repair (ECLR) (<3-months) and traditional lip repair (TLR) (3-6 months) with/without nasoalveolar molding (NAM) to evaluate the effects of surgical timing on weight gain in hopes of guiding future treatment paradigms. DESIGN Retrospective review. SETTING Children's Hospital of Los Angeles, California. PATIENT, PARTICIPANTS A retrospective chart review evaluated patients who underwent ECLR or TLR ± NAM from November 2009 through January 2020. INTERVENTIONS No intervention was performed. MAIN OUTCOME MEASURE(S) Patient demographics, birth and medical history, perioperative variables, and complications were collected. Infant weights and age-based percentiles were recorded at birth, surgery, 8-weeks, 6-months, 12-months, and 24-months postoperatively. The main outcomes were weight change and weight percentile amongst ECLR and TLR ± NAM groups. RESULTS 107 patients met inclusion criteria: ECLR, n = 51 (47.6%); TLR +...

La pandemia COVID-19 presenta una crisis sanitaria, una crisis humanitaria y una crisis económica... more La pandemia COVID-19 presenta una crisis sanitaria, una crisis humanitaria y una crisis económica, con impactos previstos a largo plazo, especialmente para las personas jóvenes quienes son el 25,2% de la población en Colombia. Esto se agrava por las múltiples o cruzadas desigualdades, como el origen étnico, la situación socioeconómica, la condición de discapacidad, la edad, la ubicación geográfica y la orientación sexual, entre otras. <br>Por ello, Profamilia en alianza con Panership Maternal Newborn and Child Health realizó una evaluación rápida sobre los desafíos, servicios y prácticas para poder superarlos con 23 adolescentes de entre 15 y 19 años y mujeres de entre 20 y 29 años. El objetivo de la investigación fue evaluar las necesidades, experiencias y prácticas resilientes de los adolescentes y las mujeres jóvenes durante la crisis del COVID-19 en Colombia, con el propósito de fundamentar las actividades de promoción y las principales respuestas de política con relevanci...

El documento está organizado en una Introducción y tres Secciones. La Introducción describe la im... more El documento está organizado en una Introducción y tres Secciones. La Introducción describe la importancia de hacer visibles las realidades experimentadas por las mujeres y los adolescentes en la defensa y las respuestas políticas a nivel mundial y nacional. La sección 1 presenta los objetivos y la metodología seguida. La Sección 2 presenta los resultados logrados y describe los desafíos y las necesidades de las adolescentes y las mujeres jóvenes durante la pandemia de COVID-19, así como las prácticas resilientes de los adolescentes y los jóvenes para enfrentar los desafíos de la pandemia. La Sección 3 contiene mensajes de promoción centrados en las experiencias de adolescentes y jóvenes durante la pandemia. Esperamos que estos resultados contribuyan a una mejor comprensión de la situación de las adolescentes y mujeres jóvenes en circunstancias vulnerables durante la pandemia de COVID-19 y que sirvan como insumo para desarrollar estrategias de respuesta eficientes.

Annals of Mediterranean Surgery, 2021

La carcinomatosis peritoneal de origen digestivo es un tema de actualidad debido a los avances en... more La carcinomatosis peritoneal de origen digestivo es un tema de actualidad debido a los avances en su tratamiento durante los últimos años. La aparición de los protocolos PIPAC (Quimioterapia en aerosol intraperitoneal presurizado) abre un nuevo camino al tratamiento paliativo de estos pacientes permitiendo, con mínima morbilidad, un alivio sintomático en las etapas finales de la enfermedad. La buena coordinación de los equipos oncológicos es de especial importancia para la correcta planificación de estos pacientes, y la inclusión en el protocolo PIPAC desde el inicio del tratamiento con intención paliativa. Presentamos nuestra experiencia adquirida tras la implementación de este protocolo, las consideraciones sobre la técnica y las dificultades que hemos notado durante su implementación.

2019 49th European Microwave Conference (EuMC), 2019

Two OAM modes are created using concentrically stacked phased circular arrays. To generate a more... more Two OAM modes are created using concentrically stacked phased circular arrays. To generate a more homogeneous intensity ring a new design parameter for N is introduced and a modes segmentation procedure is proposed to reduce interference between modes in a reception system. Furthermore, a set of design rules are exposed for determining: the minimum and maximum separation between Rx-Tx systems, allowed geometric distributions, the effect of interference on the orthogonal modes, polarization, the effects of feeding networks and the collimation of the radiation pattern through dielectric lenses. For a frequency of 24.125 GHz the separation between the Rx-Tx system is increased from 15.7 cm (without lenses) to 82.7 cm with 10λ lenses.

Advances in Media, Entertainment, and the Arts, 2019

America as a superpower is alleged to be able to set the news agenda through framing devices that... more America as a superpower is alleged to be able to set the news agenda through framing devices that even foreign media often mimics. A noteworthy theory explaining how this agenda is set is given by E.S. Hermann and Noam Chomsky in their propaganda model (PM). The PM model would assume educated elites in the US and in other comparable states (like China) will simply reiterate the framing narrative given by a state. Five films from non-American directors are selected and several issues the state has a consensus on are used (immigration, Iraq) to test the PM. In only three cases was the PM confirmed and even in those not for the reasons given by Hermann and Chomsky. In two cases the PM was moderately disconfirmed. While the PM is a valuable model, it needs refinement by taking more seriously how ideas by social groups in society such as feminism and gender equality complicate the agenda of the state. The conclusion makes recommendations how the PM can be better built to examine how non-...

Handbook of Research on Ethical Challenges in Higher Education Leadership and Administration, 2020

This chapter surveys the influence and thinking of Hannah Arendt and Che Guevara regarding educat... more This chapter surveys the influence and thinking of Hannah Arendt and Che Guevara regarding education. Despite their many differences, both thinkers are surprisingly similar in seeing authority in an ideal community as self-justifying and therefore authorizing a certain amount of repression by the state. The essay turns to the later thinking of Michel Foucault and his theory of a utopian liberalism to provide individuals a way to both join in but not be subjugated by larger collectivities. The chapter concludes that universities can embrace a form of Foucault's utopianism and allow the left and right to debate their respective positions and not need to censor views except in the most extreme cases. The goal in free speech should be to make students into thinking subjects.

Journal of Craniofacial Surgery, 2021

American Journal of Public Health, 2021

The Buprenorphine Nurse Care Manager Initiative (BNCMI) sought to increase access to opioid use d... more The Buprenorphine Nurse Care Manager Initiative (BNCMI) sought to increase access to opioid use disorder treatment in underserved New York City populations by expanding buprenorphine treatment capacity in safety-net primary care clinics. During 2016 to 2020, BNCMI added 116 new buprenorphine providers across 27 BNCMI clinics, and 1212 patients were enrolled; most patients identified as Latinx or Hispanic and were Medicaid beneficiaries. BNCMI increased access to buprenorphine, reached underserved populations, and is part of the New York City Health Department’s multipronged approach to reducing opioid overdose deaths.

The synthesis and fluorescence spectroscopy studies of 21 peptoids, including 19 new tripeptoids,... more The synthesis and fluorescence spectroscopy studies of 21 peptoids, including 19 new tripeptoids, are described. Insight into sequence features that influence biophysical properties in the presence and absence of unilamellar lipid vesicles is provided. Concomitantly, we highlight the educational value of training undergraduates in multidisciplinary research using peptoid science.

Materials Letters, 2021

Abstract In this study, the high-rate performance of high sulfur-loaded cathodes have been demons... more Abstract In this study, the high-rate performance of high sulfur-loaded cathodes have been demonstrated using a novel battery that comprises of a 3 dimensional aluminum foam (current collector), sulfur (active material), acetylene black (conductive additive), and polypyrrole (PPy) coating. Consequently, a stacked laminated cell was prepared, which comprised of two 70 × 70 mm2 PPy-sulfur/ketjen black sheets (sulfur-loading = 4.3 mg/cm2), 1 M lithium bis-(trifluoromethylsulfonyl)imide (LiTFSI) with dimethoxyethane (DME) and 1,3-dioxolane (DOL), (DME/DOL = 1/1 vol%), and three Li foils as the cathodes, electrolyte, and anodes, respectively. The 1 M LiTFSI DME/DOL electrolyte, which is suitable for high rate, is applicable because the PPy coating suppresses dissolution of polysulfide into the electrolyte. The discharge capacities were 462 mAh (1075 mAh/g sulfur) at 0.4C (267 mA) and 251 mAh (583 mAh/g-sulfur) at 3.8C (2670 mA). An enhanced conductive path was formed in the cathode by the 3D Al foam and AB, which considerably improved the high-rate performance. This demonstration is particularly significant from the viewpoint of commercializing the high-power output and high-energy–density Li-S batteries for industrial applications such as small mobile device and drone power source.

IEEE Transactions on Circuits and Systems for Video Technology, 2020

Future frame prediction in video is one of the most important problem in computer vision, and use... more Future frame prediction in video is one of the most important problem in computer vision, and useful for a range of practical applications, such as intention prediction or video anomaly detection. However, this task is challenging because of the complex and dynamic evolution of scene. The difficulty of video frame prediction is to model the inherent spatio-temporal correlation between frames and pose an adaptive and flexible framework for large motion change or appearance variation. In this paper, we construct a deep multi-branch mask network (DMMNet) which adaptively fuses the advantages of optical flow warping and RGB pixel synthesizing methods, i.e., the common two kinds of approaches in this task. In the procedure of DMMNet, we add mask layer in each branch to adaptively adjust the magnitude range of estimated optical flow and the weight of predicted frames by optical flow warping and RGB pixel synthesizing, respectively. In other words, we provide a more flexible masking network for motion and appearance fusion on video frame prediction. Exhaustive experiments on Caltech pedestrian and UCF101 datasets show that the proposed model can obtain favorable video frame prediction performance compared with the state-of-the-art methods. In addition, we also put our model into the video anomaly detection problem, and the superiority is verified by the experiments on UCSD dataset.

Nature communications, May 18, 2018

Triple-negative breast cancer (TNBC) is a highly metastatic subtype of breast cancer that has lim... more Triple-negative breast cancer (TNBC) is a highly metastatic subtype of breast cancer that has limited therapeutic options. Thus, developing novel treatments for metastatic TNBC is an urgent need. Here, we show that nanoparticle-mediated delivery of transforming growth factor-β1-activated kinase-1 (TAK1) inhibitor 5Z-7-Oxozeaenol can inhibit TNBC lung metastasis in most animals tested. P38 is a central signal downstream of TAK1 in TNBC cells in TAK1-mediated response to multiple cytokines. Following co-culturing with macrophages or fibroblasts, TNBC cells express interleukin-1 (IL1) or tumor necrosis factor-α (TNFα), respectively. Compared to TAK1 inhibition, suppressing IL1 signaling with recombinant IL1 receptor antagonist (IL1RA) is less efficient in reducing lung metastasis, possibly due to the additional TAK1 signals coming from distinct stromal cells. Together, these observations suggest that TAK1 may play a central role in promoting TNBC cell adaptation to the lung microenviro...

American journal of ophthalmology, Jan 31, 2015

To describe fluocinolone acetonide implant dissociations in the Multicenter Uveitis Steroid Treat... more To describe fluocinolone acetonide implant dissociations in the Multicenter Uveitis Steroid Treatment (MUST) Trial. Randomized clinical trial with extended follow-up. Review of data collected on the first implant in the eye(s) of participants. Dissociation was defined as the drug pellet no longer being affixed to the strut and categorized as spontaneous or surgically-related. 250 eyes (146 patients) had at least one implant placed. Median time follow-up time after implant placement was 6 years (range 0.5 to 9.2). Thirty-four dissociations were reported in 30 participants. There were 22 spontaneous events in 22 participants; 6-year cumulative risk of a spontaneous dissociation was 4.8% (95% confidence interval (CI): 2.4%-9.1%). The earliest event occurred 4.8 years after placement. Nine of 22 eyes with data had a decline in visual acuity >5 letters temporally related to the dissociation. 39 implant removal surgeries were performed, 33 with replacement. Twelve dissociations were no...

American journal of ophthalmology, Jan 16, 2015

To identify factors associated with best-corrected visual acuity (BCVA) presentation and two-year... more To identify factors associated with best-corrected visual acuity (BCVA) presentation and two-year outcome in 479 intermediate, posterior, and panuveitic eyes. Cohort study using randomized controlled trial data METHODS: Multicenter Uveitis Steroid Treatment (MUST) Trial masked BCVA measurements at baseline and 2 years' follow-up used gold standard methods. Twenty-three clinical centers documented characteristics per protocol, which were evaluated as potential predictive factors for baseline BCVA and two-year change in BCVA. Baseline factors significantly associated with reduced BCVA included: age≥50 vs. <50 years; posterior vs. intermediate uveitis; uveitis duration>10 vs. <6 years; anterior chamber (AC) flare>grade 0; cataract; macular thickening; and exudative retinal detachment. Over two years, eyes better than 20/50 and 20/50 or worse at baseline improved, on average, by 1 letter (p=0.52) and 10 letters (p<0.001) respectively. Both treatment groups and all sit...

La Houille Blanche, 2004

Taking into account the large number of hydraulic works exposed to high constraints, day to day m... more Taking into account the large number of hydraulic works exposed to high constraints, day to day maintenance of a large developed river like the Rhone needs permanent supervisions. It is especially the case for hydraulic works sub-jected to large downstream energy dissipation, because ...

Revue d'économie financière, 2005

Ingeniería e …, 2007

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The COVID-19 pandemic poses a health, humanitarian and economic crisis, with a long-term projecte... more The COVID-19 pandemic poses a health, humanitarian and economic crisis, with a long-term projected impact, especially for young people who make up 25.2% of the population in Colombia. This issue is exacerbated by multiple or overlapping inequalities, such as ethnicity, socioeconomic status, disability, age, geographic location, sexual orientation, among others.<br>For this reason, Profamilia, in alliance with Panership Maternal Newborn and Child Health, conducted a brief assessment of the challenges, services, and practices to overcome these challenges with 23 teenagers aged 15-19 and women aged 20-29. The objective of the research was to assess the needs, experiences, and resilient practices of teenagers and young women during the COVID19 crisis in Colombia, to substantiate promotional activities and key policy responses with specific relevance to women, teenagers, and young people. The analysis of these experiences has produced evidence that allows for the creation of useful...