Diego H - Academia.edu (original) (raw)

Address: Mexico, Distrito Federal, Mexico

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Papers by Diego H

Research paper thumbnail of The CMS Collaboration

Research paper thumbnail of Impaired Nonhomologous End-Joining Provokes Soft Tissue Sarcomas Harboring Chromosomal Translocations, Amplifications, and Deletions

Research paper thumbnail of Long and short-term effects of transmyocardial laser revascularization in acute myocardial ischemia

Lasers in Surgery and Medicine, 1997

This study examined the effect of transmyocardial laser revascularization (TMLR) on infarct size ... more This study examined the effect of transmyocardial laser revascularization (TMLR) on infarct size and global and regional left ventricular (LV) function. Acute ischemia was induced in 24 dogs by ligating the left anterior descending artery. TMLR was done through a left thoracotomy in 12 dogs. The 12 control dogs had ligation only. Global and regional LV function were measured before ligation, then at 6 hours or 3 months after ligation. We calculated the volumetric ratio of damaged myocardium to myocardium at risk (Vd/Vr). At 6 hours, global compensation despite regional dyskinesia was universal; Vd/Vr was the same in control and TMLR dogs. At 3 months, global function during stress was significantly higher in TMLR dogs than in control dogs (P < .05); regional contractions were synergic only in TMLR dogs; mean Vd/Vr was significantly lower in TMLR dogs. TMLR limits infarct expansion and improves long-term global and regional function after acute ischemia.

Research paper thumbnail of The human VASA gene is specifically expressed in the germ cell lineage

Proceedings of The National Academy of Sciences, 2000

Abbreviation: PGC, primordial germ cell.

Research paper thumbnail of Suppression of Ovarian Follicle Activation in Mice by the Transcription Factor Foxo3a

Science, 2003

Foxo transcription factors have been implicated in diverse biological processes, including metabo... more Foxo transcription factors have been implicated in diverse biological processes, including metabolism, cellular stress responses, and aging. Here, we show that Foxo3a-/- female mice exhibit a distinctive ovarian phenotype of global follicular activation leading to oocyte death, early depletion of functional ovarian follicles, and secondary infertility. Foxo3a thus functions at the earliest stages of follicular growth as a suppressor of follicular activation. In addition to providing a molecular entry point for studying the regulation of follicular growth, these results raise the possibility that accelerated follicular initiation plays a role in premature ovarian failure, a common cause of infertility and premature aging in women.

Research paper thumbnail of MAQUINAS HIDRÁ ULICAS UNIDAD 4 BOMBAS ROTODINAMICAS

6. Una bomba centrífuga gira a 750 rpm. El desnivel geodésico entre los depósitos de aspiración e... more 6. Una bomba centrífuga gira a 750 rpm. El desnivel geodésico entre los depósitos de aspiración e impulsión, abiertos a la atmósfera, junto con todas las pérdidas de carga exteriores a la bomba, asciende a 15 m. El ángulo  2 = 45°. La velocidad media del agua en las tuberías, así como la velocidad meridional en el interior de la bomba, se mantienen constante e igual a 2 m/s. La entrada de la corriente en los álabes es radial. El rendimiento manométrico de la bomba es 75%. Ancho del rodete a la salida 15 mm. Calcular: a) diámetro exterior del rodete; b) altura dinámica del rodete que se ha de transformar en altura de presión en la carga espiral; c) si el diámetro del rodete a la entrada es 0,4 el diámetro del rodete a la salida, calcular el caudal y el ancho del rodete a la entrada; d)    e) rendimiento de la bomba, si  m = 0,9 y  v = 1. Datos: Bomba centrífuga n = 750 rpm z 2 -z 1 + Hr 1-2 = 15 m β 2 = 45° v 1 = v 2 = c m = cte = 2 m/s entrada radial α 1 = 90° η h = 75 % b 2 = 15 mm a) d 2 = ? b) H D = ? c) Si: d 1 = 0,4d 2 , Q = ? , b 1 = ? d) β 1 = ? e) η T = ? si: η m = 0,9 y η v = 1 a) Si:

Research paper thumbnail of The CMS Collaboration

Research paper thumbnail of Impaired Nonhomologous End-Joining Provokes Soft Tissue Sarcomas Harboring Chromosomal Translocations, Amplifications, and Deletions

Research paper thumbnail of Long and short-term effects of transmyocardial laser revascularization in acute myocardial ischemia

Lasers in Surgery and Medicine, 1997

This study examined the effect of transmyocardial laser revascularization (TMLR) on infarct size ... more This study examined the effect of transmyocardial laser revascularization (TMLR) on infarct size and global and regional left ventricular (LV) function. Acute ischemia was induced in 24 dogs by ligating the left anterior descending artery. TMLR was done through a left thoracotomy in 12 dogs. The 12 control dogs had ligation only. Global and regional LV function were measured before ligation, then at 6 hours or 3 months after ligation. We calculated the volumetric ratio of damaged myocardium to myocardium at risk (Vd/Vr). At 6 hours, global compensation despite regional dyskinesia was universal; Vd/Vr was the same in control and TMLR dogs. At 3 months, global function during stress was significantly higher in TMLR dogs than in control dogs (P < .05); regional contractions were synergic only in TMLR dogs; mean Vd/Vr was significantly lower in TMLR dogs. TMLR limits infarct expansion and improves long-term global and regional function after acute ischemia.

Research paper thumbnail of The human VASA gene is specifically expressed in the germ cell lineage

Proceedings of The National Academy of Sciences, 2000

Abbreviation: PGC, primordial germ cell.

Research paper thumbnail of Suppression of Ovarian Follicle Activation in Mice by the Transcription Factor Foxo3a

Science, 2003

Foxo transcription factors have been implicated in diverse biological processes, including metabo... more Foxo transcription factors have been implicated in diverse biological processes, including metabolism, cellular stress responses, and aging. Here, we show that Foxo3a-/- female mice exhibit a distinctive ovarian phenotype of global follicular activation leading to oocyte death, early depletion of functional ovarian follicles, and secondary infertility. Foxo3a thus functions at the earliest stages of follicular growth as a suppressor of follicular activation. In addition to providing a molecular entry point for studying the regulation of follicular growth, these results raise the possibility that accelerated follicular initiation plays a role in premature ovarian failure, a common cause of infertility and premature aging in women.

Research paper thumbnail of MAQUINAS HIDRÁ ULICAS UNIDAD 4 BOMBAS ROTODINAMICAS

6. Una bomba centrífuga gira a 750 rpm. El desnivel geodésico entre los depósitos de aspiración e... more 6. Una bomba centrífuga gira a 750 rpm. El desnivel geodésico entre los depósitos de aspiración e impulsión, abiertos a la atmósfera, junto con todas las pérdidas de carga exteriores a la bomba, asciende a 15 m. El ángulo  2 = 45°. La velocidad media del agua en las tuberías, así como la velocidad meridional en el interior de la bomba, se mantienen constante e igual a 2 m/s. La entrada de la corriente en los álabes es radial. El rendimiento manométrico de la bomba es 75%. Ancho del rodete a la salida 15 mm. Calcular: a) diámetro exterior del rodete; b) altura dinámica del rodete que se ha de transformar en altura de presión en la carga espiral; c) si el diámetro del rodete a la entrada es 0,4 el diámetro del rodete a la salida, calcular el caudal y el ancho del rodete a la entrada; d)    e) rendimiento de la bomba, si  m = 0,9 y  v = 1. Datos: Bomba centrífuga n = 750 rpm z 2 -z 1 + Hr 1-2 = 15 m β 2 = 45° v 1 = v 2 = c m = cte = 2 m/s entrada radial α 1 = 90° η h = 75 % b 2 = 15 mm a) d 2 = ? b) H D = ? c) Si: d 1 = 0,4d 2 , Q = ? , b 1 = ? d) β 1 = ? e) η T = ? si: η m = 0,9 y η v = 1 a) Si:

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