Nafiye Urganci - Academia.edu (original) (raw)

Papers by Nafiye Urganci

Medical Journal of Bakırkoy, 2020

Objective: Gastrointestinal disorders may have negative impact on bone metabolism. The aim of the... more Objective: Gastrointestinal disorders may have negative impact on bone metabolism. The aim of the study was to evaluate bone metabolism and bone mineral density in children with Helicobacter pylori (H. pylori) infection. Method: A total of 100 children (mean age: 13.69±2.44 years, M/F: 0.66) with chronic gastritis were divided into two groups according to presence of H. pylori infection and were tested for biochemical parameters such as calcium, phosphorus, magnesium, alkaline phosphatase, parathyroid hormone and vitamin D. Bone mineral density was measured at lumbar spine in all of the patients by dual-energy x-ray absorptiometry (DXA). Results: 48 of 72 patients with H. pylori and 16 of 28 patients without H. pylori had low vitamin D levels (p=0.35). The other biochemical parameters were within normal limits in both groups. Bone mineral density was measured -0.16±2.25 g/cm2 in H. pylori-positive patients and -0.08±2.62 g/cm2 in H. pylori-negative patients (p=0.87). Only 2 patients...

European Journal of Pediatrics

Journal of Pediatric Infectious Diseases

Objective With the increasing prevalence of celiac disease (CD) in the population, possible risk ... more Objective With the increasing prevalence of celiac disease (CD) in the population, possible risk factors are under investigation. Environmental and genetic factors that trigger the immune response have been analyzed for many years. This study investigates the presence of CD in children with rotavirus infection. Rotavirus infection is thought to be a risk factor for CD. Methods Included in the study were 105 of 160 pediatric patients hospitalized due to symptomatic rotavirus infection between 2012 and 2018. These children were screened for CD 45.6 ± 18.2 (14–90) months following the rotavirus infection diagnosed with CD as per ESPGHAN guidelines. Results A total of 105 pediatric patients who had rotavirus gastroenteritis were included in the study. The age of the children with rotavirus infection was 3.98 ± 1 (2–6) months. In terms of CD, it was 45.6 ± 18.2 months. Around 14 to 90 months later, patients were called for control. CD developed in four (3.8%) of the children with rotavir...

Gazzetta Medica Italiana Archivio per le Scienze Mediche

Cyprus Journal of Medical Sciences

Journal of Academic Research in Medicine

JPMA. The Journal of the Pakistan Medical Association, 2018

Johanson-Blizzard Syndrome (JBS) was first described by Johanson and Blizzard. It exhibits autoso... more Johanson-Blizzard Syndrome (JBS) was first described by Johanson and Blizzard. It exhibits autosomal recessive inheritance and is characterized by mutation in the UBR1 gene on the long arm of Chromosome 15. The phenotypic features as well as diarrhoea that occurs due to the exocrine pancreatic insufficiency constitute the main clinical symptoms. This article discusses Johanson-Blizzard Syndrome due to the case followed-up by us with the symptoms of deafness and diarrhoea as well as typical facial appearance.

Iranian Journal of Pediatrics

BMC oral health, Jan 21, 2017

The oral cavity can be an extra-gastric reservoir for Helicobacter pylori (H.pylori). This can pl... more The oral cavity can be an extra-gastric reservoir for Helicobacter pylori (H.pylori). This can play a role in the pathogenesis of halitosis, glossitis, recurrent aphthous stomatitis, and dental caries. The present study was conducted to detect the presence of H.pylori within the dental biofilm and in saliva samples collected from children suffering from dyspepsia and children without any gastrointestinal complaints. Associations with gastric infection, halitosis, and some oral parameters were also evaluated. Seventy children (aged between 5-16) with dyspepsia were selected for the study group and control group composed of 30 healthy children without dyspepsia were also included in the study. After detailed oral and clinical examinations for oral parameters, saliva, and supragingival dental biofilm samples were collected for 16S rRNA and 23S rRNA genes detection by real-time polymerase chain reaction (RT-PCR). The presence of gastric H.pylori was evaluated in endoscopic biopsy specim...

Anatolian Journal of Psychiatry, 2016

Turkiye Klinikleri Journal of Pediatrics, 2014

Turk Pediatri Arsivi, 2002

Gazi Medical Journal, 2010

Turkiye Klinikleri Journal of Pediatrics, 2005

Turkiye Klinikleri Journal of Gastroenterohepatology, 2002

Turk Pediatri Arsivi, 1999

Turkiye Klinikleri Journal of Pediatrics, 2009

The Turkish Journal of Gastroenterology the Official Journal of Turkish Society of Gastroenterology, Feb 1, 2011

We aimed to identify the genetic factors associated with increased tendency toward autoimmune hep... more We aimed to identify the genetic factors associated with increased tendency toward autoimmune hepatitis, a chronic and progressive inflammatory condition. A total of 32 children diagnosed with autoimmune hepatitis were included in the present study, and 160 healthy adult blood donors served as controls. In both groups, HLA phenotypes were examined (HLA-A, B, C, DR, DQ) and compared. In addition, the association between the type of autoimmune hepatitis and HLA status was explored. Compared to controls, patients with autoimmune hepatitis had increased frequencies of the following class 1 HLA antigens: A24.9 (28% vs. 9%, p=0.007), A26 (25% vs. 3%, p<0.001), A32 (34% vs. 4%, p<0.001), B38 (9% vs. 0.6%, p=0.015), and B51 (16% vs. 0%, p<0.001). Among class II HLA antigens, DRB1*04 (22% vs. 0%, p<0.001), DRB1*07 (9% vs. 0%, p=0.004), DRB1*11 (12% vs. 0%, p=0.001), DRB1*15 (25% vs. 0%, p<0.001), DRB1*14 (31% vs. 0%, p<0.001), and DR11.5 (9% vs. 0%, p=0.004) were more frequent in patients compared to controls. Type 1 autoimmune hepatitis was associated with high frequencies of A24.9, A26, A32, and DRB1*15, whereas type 2 autoimmune hepatitis was associated with high frequencies of A26, B51, B38, and DRB1*11. On the other hand, frequencies of A32 and DRB1*04 were high among patients with unclassified autoimmune hepatitis. There seem to be associations between certain HLA antigens and susceptibility to autoimmune hepatitis, but variations among different geographical locations suggest a role for environmental factors.

Turk Pediatri Arsivi, 1998

International Journal of Infectious Diseases, 2006

Medical Journal of Bakırkoy, 2020

Objective: Gastrointestinal disorders may have negative impact on bone metabolism. The aim of the... more Objective: Gastrointestinal disorders may have negative impact on bone metabolism. The aim of the study was to evaluate bone metabolism and bone mineral density in children with Helicobacter pylori (H. pylori) infection. Method: A total of 100 children (mean age: 13.69±2.44 years, M/F: 0.66) with chronic gastritis were divided into two groups according to presence of H. pylori infection and were tested for biochemical parameters such as calcium, phosphorus, magnesium, alkaline phosphatase, parathyroid hormone and vitamin D. Bone mineral density was measured at lumbar spine in all of the patients by dual-energy x-ray absorptiometry (DXA). Results: 48 of 72 patients with H. pylori and 16 of 28 patients without H. pylori had low vitamin D levels (p=0.35). The other biochemical parameters were within normal limits in both groups. Bone mineral density was measured -0.16±2.25 g/cm2 in H. pylori-positive patients and -0.08±2.62 g/cm2 in H. pylori-negative patients (p=0.87). Only 2 patients...

European Journal of Pediatrics

Journal of Pediatric Infectious Diseases

Objective With the increasing prevalence of celiac disease (CD) in the population, possible risk ... more Objective With the increasing prevalence of celiac disease (CD) in the population, possible risk factors are under investigation. Environmental and genetic factors that trigger the immune response have been analyzed for many years. This study investigates the presence of CD in children with rotavirus infection. Rotavirus infection is thought to be a risk factor for CD. Methods Included in the study were 105 of 160 pediatric patients hospitalized due to symptomatic rotavirus infection between 2012 and 2018. These children were screened for CD 45.6 ± 18.2 (14–90) months following the rotavirus infection diagnosed with CD as per ESPGHAN guidelines. Results A total of 105 pediatric patients who had rotavirus gastroenteritis were included in the study. The age of the children with rotavirus infection was 3.98 ± 1 (2–6) months. In terms of CD, it was 45.6 ± 18.2 months. Around 14 to 90 months later, patients were called for control. CD developed in four (3.8%) of the children with rotavir...

Gazzetta Medica Italiana Archivio per le Scienze Mediche

Cyprus Journal of Medical Sciences

Journal of Academic Research in Medicine

JPMA. The Journal of the Pakistan Medical Association, 2018

Johanson-Blizzard Syndrome (JBS) was first described by Johanson and Blizzard. It exhibits autoso... more Johanson-Blizzard Syndrome (JBS) was first described by Johanson and Blizzard. It exhibits autosomal recessive inheritance and is characterized by mutation in the UBR1 gene on the long arm of Chromosome 15. The phenotypic features as well as diarrhoea that occurs due to the exocrine pancreatic insufficiency constitute the main clinical symptoms. This article discusses Johanson-Blizzard Syndrome due to the case followed-up by us with the symptoms of deafness and diarrhoea as well as typical facial appearance.

Iranian Journal of Pediatrics

BMC oral health, Jan 21, 2017

The oral cavity can be an extra-gastric reservoir for Helicobacter pylori (H.pylori). This can pl... more The oral cavity can be an extra-gastric reservoir for Helicobacter pylori (H.pylori). This can play a role in the pathogenesis of halitosis, glossitis, recurrent aphthous stomatitis, and dental caries. The present study was conducted to detect the presence of H.pylori within the dental biofilm and in saliva samples collected from children suffering from dyspepsia and children without any gastrointestinal complaints. Associations with gastric infection, halitosis, and some oral parameters were also evaluated. Seventy children (aged between 5-16) with dyspepsia were selected for the study group and control group composed of 30 healthy children without dyspepsia were also included in the study. After detailed oral and clinical examinations for oral parameters, saliva, and supragingival dental biofilm samples were collected for 16S rRNA and 23S rRNA genes detection by real-time polymerase chain reaction (RT-PCR). The presence of gastric H.pylori was evaluated in endoscopic biopsy specim...

Anatolian Journal of Psychiatry, 2016

Turkiye Klinikleri Journal of Pediatrics, 2014

Turk Pediatri Arsivi, 2002

Gazi Medical Journal, 2010

Turkiye Klinikleri Journal of Pediatrics, 2005

Turkiye Klinikleri Journal of Gastroenterohepatology, 2002

Turk Pediatri Arsivi, 1999

Turkiye Klinikleri Journal of Pediatrics, 2009

The Turkish Journal of Gastroenterology the Official Journal of Turkish Society of Gastroenterology, Feb 1, 2011

We aimed to identify the genetic factors associated with increased tendency toward autoimmune hep... more We aimed to identify the genetic factors associated with increased tendency toward autoimmune hepatitis, a chronic and progressive inflammatory condition. A total of 32 children diagnosed with autoimmune hepatitis were included in the present study, and 160 healthy adult blood donors served as controls. In both groups, HLA phenotypes were examined (HLA-A, B, C, DR, DQ) and compared. In addition, the association between the type of autoimmune hepatitis and HLA status was explored. Compared to controls, patients with autoimmune hepatitis had increased frequencies of the following class 1 HLA antigens: A24.9 (28% vs. 9%, p=0.007), A26 (25% vs. 3%, p<0.001), A32 (34% vs. 4%, p<0.001), B38 (9% vs. 0.6%, p=0.015), and B51 (16% vs. 0%, p<0.001). Among class II HLA antigens, DRB1*04 (22% vs. 0%, p<0.001), DRB1*07 (9% vs. 0%, p=0.004), DRB1*11 (12% vs. 0%, p=0.001), DRB1*15 (25% vs. 0%, p<0.001), DRB1*14 (31% vs. 0%, p<0.001), and DR11.5 (9% vs. 0%, p=0.004) were more frequent in patients compared to controls. Type 1 autoimmune hepatitis was associated with high frequencies of A24.9, A26, A32, and DRB1*15, whereas type 2 autoimmune hepatitis was associated with high frequencies of A26, B51, B38, and DRB1*11. On the other hand, frequencies of A32 and DRB1*04 were high among patients with unclassified autoimmune hepatitis. There seem to be associations between certain HLA antigens and susceptibility to autoimmune hepatitis, but variations among different geographical locations suggest a role for environmental factors.

Turk Pediatri Arsivi, 1998

International Journal of Infectious Diseases, 2006