Zaki Uitm - Academia.edu (original) (raw)
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Institute of Bioresources and Sustainable Development (IBSD), Dept. of Biotechnology, Govt. of India, Takyelpat Institutional Area, Imphal. India
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Papers by Zaki Uitm
Evidence-Based Complementary and Alternative Medicine, 2011
Zingiber zerumbet Sm., locally known to the Malay as "Lempoyang," is a perennial herb found in ma... more Zingiber zerumbet Sm., locally known to the Malay as "Lempoyang," is a perennial herb found in many tropical countries, including Malaysia. The rhizomes of Z. zerumbet, particularly, have been regularly used as food flavouring and appetizer in various Malays' cuisines while the rhizomes extracts have been used in Malay traditional medicine to treat various types of ailments (e.g., inflammatory-and pain-mediated diseases, worm infestation and diarrhea). Research carried out using different in vitro and in vivo assays of biological evaluation support most of these claims. The active pharmacological component of Z. zerumbet rhizomes most widely studied is zerumbone. This paper presents the botany, traditional uses, chemistry, and pharmacology of this medicinal plant.
A study on improving training efficiency of Artificial Neural Networks algorithm was carried out ... more A study on improving training efficiency of Artificial Neural Networks algorithm was carried out throughout manyprevious works. This paper presents a new approach to improve the training efficiency of back propagation neural networkalgorithms. The proposed algorithm (GDM/AG) adaptively modifies the gradient based search direction by introducing thevalue of gain parameter in the activation function. It has been shown that this modification significantly enhance thecomputational efficiency of training process. The proposed algorithm is generic and can be implemented in almost all gradientbased optimization processes. The robustness of the proposed algorithm is shown by comparing convergence rates and theeffectiveness of gradient descent methods using the proposed method on heart disease data.
This study compared the efficacy of Lactobacillus casei strain Shirota (LAB13) and a probiotic co... more This study compared the efficacy of Lactobacillus casei strain Shirota (LAB13) and a probiotic cocktail for
their anti-obesity and other lipid profile modulating effects. Diet-induced obese rats were supplemented
with two different probiotics which are LAB13 (1 9 109 CFU day
1 per rat) and cocktail of five bacterial
strains (1 9 109 CFU day
1 per rat) for 12 weeks. Comparative data on weight gain, energy intake, liver
weight, subcutaneous fat, total fat weights, total cholesterol and leptin levels in both treatment groups
showed significant reduction in probiotic-treated groups compared to the obese control group. Both probiotics
have the anti-obesity and hypocholesterolaemic effects and are able to reduce body weight and fats
via reduction in energy intake. Only LAB13 was able to reduce the level of triglyceride significantly. Therefore,
the LAB13 is equally effective compared to the probiotic cocktail in weight reduction. LAB13 is more
effective in improving lipid profile which is a common medical complication of obesity.
Evidence-Based Complementary and Alternative Medicine, 2011
Zingiber zerumbet Sm., locally known to the Malay as "Lempoyang," is a perennial herb found in ma... more Zingiber zerumbet Sm., locally known to the Malay as "Lempoyang," is a perennial herb found in many tropical countries, including Malaysia. The rhizomes of Z. zerumbet, particularly, have been regularly used as food flavouring and appetizer in various Malays' cuisines while the rhizomes extracts have been used in Malay traditional medicine to treat various types of ailments (e.g., inflammatory-and pain-mediated diseases, worm infestation and diarrhea). Research carried out using different in vitro and in vivo assays of biological evaluation support most of these claims. The active pharmacological component of Z. zerumbet rhizomes most widely studied is zerumbone. This paper presents the botany, traditional uses, chemistry, and pharmacology of this medicinal plant.
A study on improving training efficiency of Artificial Neural Networks algorithm was carried out ... more A study on improving training efficiency of Artificial Neural Networks algorithm was carried out throughout manyprevious works. This paper presents a new approach to improve the training efficiency of back propagation neural networkalgorithms. The proposed algorithm (GDM/AG) adaptively modifies the gradient based search direction by introducing thevalue of gain parameter in the activation function. It has been shown that this modification significantly enhance thecomputational efficiency of training process. The proposed algorithm is generic and can be implemented in almost all gradientbased optimization processes. The robustness of the proposed algorithm is shown by comparing convergence rates and theeffectiveness of gradient descent methods using the proposed method on heart disease data.
This study compared the efficacy of Lactobacillus casei strain Shirota (LAB13) and a probiotic co... more This study compared the efficacy of Lactobacillus casei strain Shirota (LAB13) and a probiotic cocktail for
their anti-obesity and other lipid profile modulating effects. Diet-induced obese rats were supplemented
with two different probiotics which are LAB13 (1 9 109 CFU day
1 per rat) and cocktail of five bacterial
strains (1 9 109 CFU day
1 per rat) for 12 weeks. Comparative data on weight gain, energy intake, liver
weight, subcutaneous fat, total fat weights, total cholesterol and leptin levels in both treatment groups
showed significant reduction in probiotic-treated groups compared to the obese control group. Both probiotics
have the anti-obesity and hypocholesterolaemic effects and are able to reduce body weight and fats
via reduction in energy intake. Only LAB13 was able to reduce the level of triglyceride significantly. Therefore,
the LAB13 is equally effective compared to the probiotic cocktail in weight reduction. LAB13 is more
effective in improving lipid profile which is a common medical complication of obesity.