ANATOMY SLIMS | JIPMER - Academia.edu (original) (raw)

Papers by ANATOMY SLIMS

Journal of basic and clinical physiology and pharmacology, Mar 29, 2021

Objectives The threat to human health or the surroundings by the use of artificial fruit ripening... more Objectives The threat to human health or the surroundings by the use of artificial fruit ripening agents has become a global concern. Calcium carbide (CaC2) and ethylene glycol (EG) are the two widely using ripening agents. The present study evaluates the toxic effect of chronic exposures of CaC2 and EG in rats. Methods CaC2 and EG were administered to the rats for 180 days orally. The alterations in oxido-reduction status, haematological, biochemical and histopathological parameters were analysed. Arsenic content in CaC2 and animal samples were detected by atomic absorption spectrometer and phosphorus by molybdate-UV method. Results At chronic doses, there were no significant alterations in haematological and biochemical parameters except in creatinine level especially by EG. However, histological details revealed microvesicular fatty change in liver, corpuscles degeneration in kidney and lymphocytes infiltration in various tissues. In intestine, the mucosal lesion scoring was found high (p<0.01). SOD and CAT activities and GSH level was reduced significantly by CaC2 administration (p<0.01). Arsenic and phosphorus detected is above the toxic level: 7.222 and 13.91 mg/dL in CaC2, 1.634 and 6.22 mg/dL in blood and 0.563 and 6.99 mg/dL in liver, respectively. Conclusions The study suggests that the industrial grade CaC2 and EG induce systemic toxicity to rats and the liver is the most susceptible organ. The CaC2 and EG toxicity is mediated through the upset of redox balance and subsequent inflammatory responses. This could be due to the presence of arsenic and phosphorus contents that detected above the normal level in the industrial grade CaC2.

The journal of hand surgery, Apr 20, 2020

Background: Palmaris longus tendon is often used as a donor tendon by surgeons in tendon grafts. ... more Background: Palmaris longus tendon is often used as a donor tendon by surgeons in tendon grafts. It is one of the flexor muscles of the forearm and documented well for its variations in both morphology and number of tendons. Prevalence of absence of this muscle varies among the individuals of same population and individuals of various ethnic groups. The aim of this study was to assess the existence of Palmaris longus muscle within a group of students and its association with side of the limb and gender of the individual.Methods: Three hundred medical students of 150 males and 150 females with age group of 18–21 years were clinically assessed. The standard Schaffer’s test was used for the assessment of PL tendon. If the tendon was not found in this test, the confirmation was done by other four tests.Results: Results of this study shows that an overall absence of palmaris longus muscle in both sexes was found to be 32%, out of which 21% absence was found in males and 43% absence found in females. Among the males, the unilateral agenesis was seen in 16% and bilateral agenesis in 4% and in females the unilateral agenesis was seen in 29% and bilateral agenesis seen in 14%.Conclusions: To conclude; in the present study, prevalence of Palmaris longus muscle agenesis was found to be more in female subjects on their left side. Surgeons who plan for tendon reconstructive procedures should know variations of Palmaris longus muscle and its clinical assessment.

Advances in autism, Sep 26, 2019

Adolescence is a phase of rapid growth and development during which physical, physiological and b... more Adolescence is a phase of rapid growth and development during which physical, physiological and behavioural changes occur. They constitute more than 1.2 billion worldwide, and about 21% of Indian population. Morbidity and mortality occurring in this age group is mostly due to preventable causes. Adolescent risky behavior often results from their inadequate knowledge and lack of understanding of the risks involved. Aim: The aim of the study was to assess the effectiveness of video assisted teaching on the knowledge and perception on high-risk behaviours among adolescent boys. Materials and Methods: Experimental design was used. By using systematic random sampling 40 students studying from 6 th , 7 th and 8 th standard were selected. Results: Maximum number of students were in the age group of 12 years (42.5%). Half of the students were studying in 7 th standard (50%), Maximum students were residing at rural areas (60%). Majority of the students 31(77.5%) were Hindus. 12(30%) of the student's fathers were smokers, 16(40%) of the student's fathers were alcoholics. The mean knowledge score in the experimental group after the intervention (16.1) was higher than the mean knowledge score before the intervention (9.5). The mean perception score in the experimental group after the intervention (85) was higher than the mean perception score before the intervention (78.8). Conclusion: Smoking prevention is an important issue and healthcare professionals, especially nurses have a major role in helping people to understand the consequences of smoking for their lives.

Journal of basic and clinical physiology and pharmacology, Jun 28, 2021

Journal of Clinical and Diagnostic Research, 2017

Introduction: The increasing scientific evidence of various health hazards on exposure of Radiofr... more Introduction: The increasing scientific evidence of various health hazards on exposure of Radiofrequency Radiation (RFR) emitted from both the cell phones and base stations have caused significant media attention and public discussion in recent years. The mechanism of interaction of RF fields with developing tissues of children and fetuses may be different from that of adults due to their smaller physical size and variation in tissue electromagnetic properties. The present study may provide an insight into the basic mechanisms by which RF fields interact with developing tissues in an embryo. Aim: To evaluate the possible tissue and DNA damage in developing liver of chick embryo following chronic exposure to Ultra-High Frequency/Radiofrequency Radiation (UHF/RFR) emitted from 2G and 3G cell phone.

Pectoralis minimus is a rare muscle usually found in the pectoral region. The aberrant muscle in ... more Pectoralis minimus is a rare muscle usually found in the pectoral region. The aberrant muscle in the present report was arising from the first two costal cartilages and the second chondro-sternal joint of right side. The tendon of the muscle inserted into the superior surface of coracoid process and continued laterally to merge with coracoacromial ligament and coracohumeral ligament. This muscle was unique in its attachment and not reported previously. Pectoralis minimus may help in scapulo humeral rhythm. The knowledge of this aberrant muscle helps radiologist and surgeons in the diagnosis and surgical interventions of the area.

The Journal of Hand Surgery (Asian-Pacific Volume), 2020

International Journal of Research in Pharmaceutical Sciences, 2020

Polycystic ovarian syndrome is a female reproductive defect with a prevalence rate of 2.2% to 26%... more Polycystic ovarian syndrome is a female reproductive defect with a prevalence rate of 2.2% to 26% in the world and Indian adolescents at a rate of 9.13%. The polycystic ovarian syndrome is a heterogeneous endocrine syndrome related to increase in the secretion of hyperandrogenemia with increasing risk of hyperinsulinism, type 2 diabetes mellitus, Hirsutism dyslipidemia, cardiovascular diseases and finally leading to an endometrial tumor. The endocrine hormones are regulated by various factors like environment, photoperiod, ambient temperature, relative humidity availability of food, etc. Cynodon dactylon or Bermuda grass is seen all over the world. C. dactylon is a stoloniferous, hardy perennial grass, very much variable with long rapid growing, rooting at nodes, forming a dense tuft on the top of the soil.C.dactylon plant was collected and 100gm of plant powder was mixed with 1,000ml of distilled water and heated till boiling temperature. The mixture was filtered and lyophilization...

Journal of Basic and Clinical Physiology and Pharmacology, 2019

Background Naturally ripened fruits play a vital role in human nutrition. Under certain condition... more Background Naturally ripened fruits play a vital role in human nutrition. Under certain conditions, synthetic chemicals like calcium carbide (CaC2) and ethylene glycol (EG) are being freely used illegally in India and other countries for fruit ripening without serious concern on its toxic effects. This preclinical study evaluated the toxicity on different organs after the exposure of industrial-grade CaC2 and EG to the rats. Methods Acute toxicity was induced by the oral administration of a single dose of chemicals to the rats, and their morbidity and mortality were monitored. For subacute study, different organs of animals were analyzed biochemically and histologically after the exposure of low doses of chemicals for 30 days. Results At an acute dose of 5 mg/kg body weight of CaC2, 85% of the animals were found dead within 14 days; however, no mortality was observed following EG administration. At subacute doses, RBC and hemoglobin levels were found to be declined (p < 0.01), wh...

Current Pediatric Research

The present study was conducted to find out the difference in the weight, height, upper segment, ... more The present study was conducted to find out the difference in the weight, height, upper segment, lower segment and armspan of Down’s syndrome children compared to controls in the preschool period. All the above said parameters were significantly lower in cases compared to the controls. However; when grouped into age groups, the weight of these children was significantly decreased in 0 to 24 months in case of males, while in females between 9 to 24 months only. Height, upper segment and armspan measurements were significantly decreased in 0 to 9 months age group in male children. Among female children only upper segment was significantly decreased in 9 to 24 months age group.

Indian journal of pediatrics, 2004

Acephalus Acardia is an uncommon congenital malformation due to twin reverse arterial perfusion s... more Acephalus Acardia is an uncommon congenital malformation due to twin reverse arterial perfusion syndrome. In this condition the donor twin provides circulation for itself and the recipient acardiac twin. The acardiac twin is grossly abnormal with severe reduction anomalies of the upper part of the body. We report a case with autopsy findings and review of literature.

International Journal of Medicine and Biomedical Research, 2013

Background: The acute angle produced medially when the axis of the forearm deviates laterally fro... more Background: The acute angle produced medially when the axis of the forearm deviates laterally from the long axis of the humerus, with the arm extended and the palm facing forward, is referred t o as the carrying angle. Variations in the angle have clinical as well as pathological significance. Aim: This study was conducted to evaluate the elbow carrying angle in normal adolescents of South India and also analyze the data statistically to find out any significant difference in the angle between the different groups of subjects within the study population. Methods: 60 adolescents with ages varying from 17 to 20 years were evaluated. Carrying angles formed by the long axis of the humerus and ulna, were measured. Results: The result of the study showed that the average carrying angle was 13.6 degrees for females and 6.7 degrees for males. The length of the forearm and the carrying angle showed significant relation. Conclusion: The result of the study could be useful in the management of elbow displacement, fractures, epicondylar disease and surgical planning for elbow reconstruction.

Indian Journal of Ophthalmology, 2005

... Goldenhar's sequence with associated juvenile glaucoma in Turner's syndrome Vasudev... more ... Goldenhar's sequence with associated juvenile glaucoma in Turner's syndrome Vasudev Anand Rao, Subashini Kaliaperumal, Thanikachalam Subramanyan, Kotapalli Ramachandra Rao, Rajesh Bhargavan Department of Ophthalmology Jawaharlal Institute of Postgraduate ...

Fundamental & Clinical Pharmacology, 2009

Oxidative stress is implicated as a common pathologic mechanism contributing to the initiation an... more Oxidative stress is implicated as a common pathologic mechanism contributing to the initiation and progression of hepatic damage in a variety of liver disorders. Present study attempts to evaluate the hepatoprotective activity of picroliv, curcumin and ellagic acid in comparison to silymarin using paracetamol (PCM) induced acute liver damage. Hepatotoxicity was induced by administering a single oral dose of PCM (500 mg/kg) and was assessed by quantifying the serum enzyme activities, phenobarbitone induced sleeping time and histopathological analysis of liver tissues. The antioxidant parameters, malondialdehyde (MDA), reduced glutathione (GSH) and catalase of the liver tissue were also assessed. The herbal drugs were administered for 7 days by oral route at 50 and 100 mg/kg. PCM induced hepatic damage was manifested by a significant increase in the activities of marker enzymes (alanine transaminase, aspartate transaminase and alkaline phosphatase) in serum and MDA level in liver. The...

The Indian journal of medical research, 2009

Polyherbal formulations available with a wide range of indications like protective to liver, appe... more Polyherbal formulations available with a wide range of indications like protective to liver, appetite and growth promoters, gastrointestinal and hepatic regulator, as treatment for hepatic dysfunction, for hepatic regeneration as well as liver stimulant and tonic. Despite the widespread use, there is a lack of scientific evidence on their efficacy and safety. This study was undertaken to evaluate the hepatoprotective activity of six commercially available formulations, namely Liv 52, Livergen, Livokin, Octogen, Stimuliv and Tefroliv in acute liver toxicity in mice model induced by paracetamol (PCM). Swiss albino mice of either sex were used, divided in 28 groups with six in each group. The dose of the polyherbal formulations was calculated from human dose (20 ml/day) using a standard conversion table. They were given as pretreatment (2.60 ml/kg/day) for 7 days by oral route twice a day prior to PCM administration. Hepatotoxicity was induced by administering a single oral dose of PCM...

Journal of evolution of medical and dental sciences, Mar 23, 2020

BACKGROUND Females are more prone for lateral displacement of patella than males due to increased... more BACKGROUND Females are more prone for lateral displacement of patella than males due to increased Q-angle (15-18°) in them compared to males (12-15°). In a normal state, lateral displacement is prevented by geometry of the joint and by the passive stabilizers. Even though contraction of the quadriceps tends to displace the patella laterally, vastus medialis oblique (VMO) acts medially and posteriorly as much as it acts proximally, and so its tension helps in resisting the Q angle effect. There are two procedures in common practice to reduce Q-angle and thereby to prevent lateral displacement of patella-either through vastus medialis oblique (VMO) strengthening or by isometric quadriceps activation (quadriceps muscle strengthening). We wanted to compare the effects of isometric quadriceps activation and VMO strengthening in reducing Q angle in a group of young females. METHODS A non-randomized, two group, pre-test, post-test assessment of Q-angle was done. Twenty healthy females of 18-20 age group were selected and randomly divided into two groups. Isometric quadriceps activation and VMO strengthening was done for 4 weeks. Q-angles were measured before and after the strengthening exercise using a long arm goniometer. RESULTS The mean q angle before treatment was 21. (minimum 20 and maximum 23). While after the treatment, q angles were significantly reduced in both the groups and mean q angle was 16.3. CONCLUSIONS Both the isometric quadriceps activation and VMO strengthening reduced Q-angle significantly and there was no significant difference between the two procedures. Results of this study help the physiotherapist in choosing the exercise for the management of patellofemoral pain and lateral displacement of patella.

Indian journal of anatomy, 2018

Advances in anatomy, Sep 17, 2014

A Mobile phone in operation emits a pulsed radiofrequency electromagnetic field which is absorbed... more A Mobile phone in operation emits a pulsed radiofrequency electromagnetic field which is absorbed into the user's body particularly the head region. Contradictory scientific reports on the health effect of nonionizing radiations on biological tissues have prompted to undertake the present study to evaluate the damage in the developing lens of a chick embryo following exposure to radiation emitted from a 2G cell phone. Fertilized chick embryos were incubated in two groups in a standard egg incubator. The experiment group was exposed to radiation emitted from a 2G cell phone. On completion of scheduled duration, the embryos were collected and processed for routine histological studies. The 9th to 12th day chick embryo eyes were processed for assessment of DNA damage using the alkaline comet assay technique. The lens thickness and the equatorial diameter were measured using oculometer and statistically compared for both groups. In the present study, the exposure of chick embryos to a 2G cell phone caused structural changes in lens epithelial cells, formation of cystic cells and spaces, distortion of lens fibers, and formation of posterior aberrant nuclear layer. The DNA damage in the developing eyes of the experiment group assessed by comet assay was highly significant.

JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH, 2021

Introduction: The cellular phones/mobile phones have emerged as the fastest growing man-made phen... more Introduction: The cellular phones/mobile phones have emerged as the fastest growing man-made phenomenon ever discovered in the history. Controversies still exist among the scientific community regarding the ill-effects of Radiofrequency Radiation (RFR) exposure from cell phones on biological tissues. The present study will provide an insight into the basic mechanisms by which RF fields interact with developing brain in an embryo. Aim: To assess the possible Deoxyribonucleic Acid (DNA) damage in developing brain of chick embryo following chronic exposure to Ultra-High Frequency/Radiofrequency Radiation (UHF/RFR) emitted from 2G and 3G cell phone. Materials and Methods: Fertilised hen eggs were divided into three groups. Experimental Group A (exposed to 2G radiation, 24 eggs), Experimental Group B (exposed to 3G radiation, 24 eggs) and Group C sham exposed control group (24 eggs). After the completion of scheduled duration of exposure (72 minutes per day), the chick embryos were sacri...

Journal of Evolution of Medical and Dental Sciences, 2020