Microtubule-associated deacetylase HDAC6 promotes angiogenesis by regulating cell migration in an EB1-dependent manner (original) (raw)
References
Bertos, N.R., Gilquin, B., Chan, G.K., Yen, T.J., Khochbin, S., and Yang, X.J. (2004). Role of the tetradecapeptide repeat domain of human histone deacetylase 6 in cytoplasmic retention. J Biol Chem 279, 48246–48254. Article Google Scholar
Bornens, M. (2008). Organelle positioning and cell polarity. Nat Rev Mol Cell Biol 9, 874–886. Article Google Scholar
Boyault, C., Sadoul, K., Pabion, M., and Khochbin, S. (2007). HDAC6, at the crossroads between cytoskeleton and cell signaling by acetylation and ubiquitination. Oncogene 26, 5468–5476. Article Google Scholar
Chang, S., Young, B.D., Li, S., Qi, X., Richardson, J.A., and Olson, E. N. (2006). Histone deacetylase 7 maintains vascular integrity by repressing matrix metalloproteinase 10. Cell 126, 321–334. Article Google Scholar
Fischer, D.D., Cai, R., Bhatia, U., Asselbergs, F.A., Song, C., Terry, R., Trogani, N., Widmer, R., Atadja, P., and Cohen, D. (2002). Isolation and characterization of a novel class II histone deacetylase, HDAC10. J Biol Chem 277, 6656–6666. Article Google Scholar
Folkman, J. (2007). Angiogenesis: an organizing principle for drug discovery? Nat Rev Drug Discov 6, 273–286. Article Google Scholar
Gao, J., Sun, L., Huo, L., Liu, M., Li, D., and Zhou, J. (2010). CYLD regulates angiogenesis by mediating vascular endothelial cell migration. Blood 115, 4130–4137. Article Google Scholar
Guardiola, A.R., and Yao, T.P. (2002). Molecular cloning and characterization of a novel histone deacetylase HDAC10. J Biol Chem 277, 3350–3356. Article Google Scholar
Haberland, M., Montgomery, R.L., and Olson, E.N. (2009). The many roles of histone deacetylases in development and physiology: implications for disease and therapy. Nat Rev Genet 10, 32–42. Article Google Scholar
Haggarty, S.J., Koeller, K.M., Wong, J.C., Grozinger, C.M., and Schreiber, S.L. (2003). Domain-selective small-molecule inhibitor of histone deacetylase 6 (HDAC6)-mediated tubulin deacetylation. Proc Natl Acad Sci U S A 100, 4389–4394. Article Google Scholar
Kim, M.S., Kwon, H.J., Lee, Y.M., Baek, J.H., Jang, J.E., Lee, S.W., Moon, E.J., Kim, H.S., Lee, S.K., Chung, H.Y., et al. (2001). Histone deacetylases induce angiogenesis by negative regulation of tumor suppressor genes. Nat Med 7, 437–443. Article Google Scholar
Lamalice, L., Le Boeuf, F., and Huot, J. (2007). Endothelial cell migration during angiogenesis. Circ Res 100, 782–794. Article Google Scholar
Lansbergen, G., and Akhmanova, A. (2006). Microtubule plus end: a hub of cellular activities. Traffic 7, 499–507. Article Google Scholar
Lee, Y.S., Lim, K.H., Guo, X., Kawaguchi, Y., Gao, Y., Barrientos, T., Ordentlich, P., Wang, X.F., Counter, C.M., and Yao, T.P. (2008). The cytoplasmic deacetylase HDAC6 is required for efficient oncogenic tumorigenesis. Cancer Res 68, 7561–7569. Article Google Scholar
Li, R., and Gundersen, G.G. (2008). Beyond polymer polarity: how the cytoskeleton builds a polarized cell. Nat Rev Mol Cell Biol 9, 860–873. Article Google Scholar
Marks, P.A. (2007). Discovery and development of SAHA as an anticancer agent. Oncogene 26, 1351–1356. Article Google Scholar
McKinsey, T.A., Zhang, C.L., Lu, J., and Olson, E.N. (2000). Signal-dependent nuclear export of a histone deacetylase regulates muscle differentiation. Nature 408, 106–111. Article Google Scholar
Rodriguez, O.C., Schaefer, A.W., Mandato, C.A., Forscher, P., Bement, W.M., and Waterman-Storer, C.M. (2003). Conserved microtubule-actin interactions in cell movement and morphogenesis. Nat Cell Biol 5, 599–609. Article Google Scholar
Semenza, G.L. (2007). Vasculogenesis, angiogenesis, and arteriogenesis: mechanisms of blood vessel formation and remodeling. J Cell Biochem 102, 840–847. Article Google Scholar
Urbich, C., Rössig, L., Kaluza, D., Potente, M., Boeckel, J.N., Knau, A., Diehl, F., Geng, J.G., Hofmann, W.K., Zeiher, A.M., et al. (2009). HDAC5 is a repressor of angiogenesis and determines the angiogenic gene expression pattern of endothelial cells. Blood 113, 5669–5679. Article Google Scholar
Valenzuela-Fernández, A., Cabrero, J.R., Serrador, J.M., and Sánchez-Madrid, F. (2008). HDAC6: a key regulator of cytoskeleton, cell migration and cell-cell interactions. Trends Cell Biol 18, 291–297. Article Google Scholar
Vega, R.B., Harrison, B.C., Meadows, E., Roberts, C.R., Papst, P.J., Olson, E.N., and McKinsey, T.A. (2004). Protein kinases C and D mediate agonist-dependent cardiac hypertrophy through nuclear export of histone deacetylase 5. Mol Cell Biol 24, 8374–8385. Article Google Scholar
Xu, W.S., Parmigiani, R.B., and Marks, P.A. (2007). Histone deacetylase inhibitors: molecular mechanisms of action. Oncogene 26, 5541–5552. Article Google Scholar
Zhang, Y., Kwon, S., Yamaguchi, T., Cubizolles, F., Rousseaux, S., Kneissel, M., Cao, C., Li, N., Cheng, H.L., Chua, K., et al. (2008). Mice lacking histone deacetylase 6 have hyperacetylated tubulin but are viable and develop normally. Mol Cell Biol 28, 1688–1701. Article Google Scholar
Zilberman, Y., Ballestrem, C., Carramusa, L., Mazitschek, R., Khochbin, S., and Bershadsky, A. (2009). Regulation of microtubule dynamics by inhibition of the tubulin deacetylase HDAC6. J Cell Sci 122, 3531–3541. Article Google Scholar