Dionicio Siegel • UCSD Profiles (original) (raw)

1. MS/MS Mass Spectrometry Filtering Tree for Bile Acid Regio- and Stereoisomer Annotation. Anal Chem. 2026 Feb 17; 98(6):4571-4584. Mohanty I, Xing S, Castillo V, Agongo J, Patan A, El Abiead Y, Mannochio-Russo H, Gonçalves Nunes WD, Zemlin J, Mizrahi I, Siegel D, Wang M, Hagey LR, Dorrestein PC. PMID: 41642850; PMCID: PMC12921657.
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   Translation:Animals
2. ATGL-catalyzed biosynthesis mediates the upregulation of fatty acid hydroxy fatty acids (FAHFA) levels in white adipose tissue with fasting. J Biol Chem. 2026 Jan 20; 302(3):111169. Santoro A, Chen Z, Nelson AT, Siegel D, Kahn BB. PMID: 41570983; PMCID: PMC12934275.
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3. View in: PubMed Mentions:
4. The microbiome diversifies long- to short-chain fatty acid-derived N-acyl lipids. Cell. 2025 Jul 24; 188(15):4154-4169.e19. Mannochio-Russo H, Charron-Lamoureux V, van Faassen M, Lamichhane S, Gonçalves Nunes WD, Deleray V, Ayala AV, Tanaka Y, Patan A, Vittali K, Rajkumar P, El Abiead Y, Zhao HN, Gomes PWP, Mohanty I, Lee C, Sund A, Sharma M, Liu Y, Pattynama D, Walker GT, Norton GJ, Khatib L, Andalibi MS, Wang CX, Ellis RJ, Moore DJ, Iudicello JE, Franklin D, Letendre S, Chin L, Walker C, Renwick S, Zemlin J, Meehan MJ, Song X, Kasper D, Burcham Z, Kim JJ, Kadakia S, Raffatellu M, Bode L, Chu H, Zengler K, Wang M, Siegel D, Knight R, Dorrestein PC. PMID: 40499541; PMCID: PMC12428309.
   View in: PubMed Mentions: 6 Fields:
   Translation:Humans
5. Specific FAHFAs predict worsening glucose tolerance in non-diabetic relatives of people with Type 2 diabetes. J Lipid Res. 2025 Jul; 66(7):100819. Syed I, Sluis K, Aryal P, Solomon Z, Patel R, Konduri S, Siegel D, Smith U, Kahn BB. PMID: 40334782; PMCID: PMC12271064.
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6. MS/MS Mass Spectrometry Filtering Tree for Bile Acid Isomer Annotation. bioRxiv. 2025 Mar 09. Mohanty I, Xing S, Castillo V, Agongo J, Patan A, Abiead YE, Mannochio-Russo H, Zuffa S, Zemlin J, Tronel A, Gouellec AL, Soranzo T, Wang CX, Iudicello JE, Andalibi MS, Ellis RJ, Moore DJ, Franklin DR, Sala-Climent M, Guma M, Voigt RM, Kaddaruh-Dauok R, Siegel D, Wang M, Hagey LR, Dorrestein PC. PMID: 41659560; PMCID: PMC12874289.
   View in: PubMed Mentions: 1
7. Acute inflammation upregulates FAHFAs in adipose tissue and in differentiated adipocytes. J Biol Chem. 2024 12; 300(12):107972. Ertunc ME, Konduri S, Ma Z, Pinto AFM, Donaldson CJ, Momper J, Siegel D, Saghatelian A. PMID: 39510180; PMCID: PMC11647607.
   View in: PubMed Mentions: 1 Fields:
   Translation:AnimalsCells
8. The microbiome diversifies N-acyl lipid pools - including short-chain fatty acid-derived compounds. bioRxiv. 2024 Nov 02. Mannochio-Russo H, Charron-Lamoureux V, van Faassen M, Lamichhane S, Nunes WDG, Deleray V, Patan A, Vittali K, Rajkumar P, El Abiead Y, Zhao HN, Gomes PWP, Mohanty I, Lee C, Sund A, Sharma M, Liu Y, Pattynama D, Walker GT, Norton GJ, Khatib L, Andalibi MS, Wang CX, Ellis RJ, Moore DJ, Iudicello JE, Franklin D, Letendre S, Chin L, Walker C, Renwick S, Zemlin J, Meehan MJ, Song X, Kasper D, Burcham Z, Kim JJ, Kadakia S, Raffatellu M, Bode L, Zengler K, Wang M, Siegel D, Knight R, Dorrestein PC. PMID: 39554097; PMCID: PMC11565975.
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9. Development of a Prepharmacy Underrepresented Mentorship Program for Undergraduate Students. Am J Pharm Educ. 2024 Sep; 88(9):101260. Mnatzaganian CL, Fricovsky E, Cartlidge C, Siqueira-Neto J, Siegel D, Cooper D, Lee KC, Atayee RS. PMID: 39128793.
   View in: PubMed Mentions: Fields:
   Translation:Humans
10. Beneficial metabolic effects of PAHSAs depend on the gut microbiota in diet-induced obese mice but not in chow-fed mice. Proc Natl Acad Sci U S A. 2024 Jul 09; 121(28):e2318691121. Lee J, Wellenstein K, Rahnavard A, Nelson AT, Holter MM, Cummings BP, Yeliseyev V, Castoldi A, Clish CB, Bry L, Siegel D, Kahn BB. PMID: 38968121; PMCID: PMC11252816.
    View in: PubMed Mentions: 2 Fields:
    Translation:Animals
11. Tracking Inhibition of Human Small C-Terminal Domain Phosphatase 1 Using 193 nm Ultraviolet Photodissociation Mass Spectrometry. J Am Soc Mass Spectrom. 2024 Jun 05; 35(6):1330-1341. Escobar EE, Yang W, Lanzillotti MB, Juetten KJ, Shields S, Siegel D, Zhang YJ, Brodbelt JS. PMID: 38662915; PMCID: PMC11384422.
    View in: PubMed Mentions: 1 Fields:
    Translation:HumansCells
12. The underappreciated diversity of bile acid modifications. Cell. 2024 Mar 28; 187(7):1801-1818.e20. Mohanty I, Mannochio-Russo H, Schweer JV, El Abiead Y, Bittremieux W, Xing S, Schmid R, Zuffa S, Vasquez F, Muti VB, Zemlin J, Tovar-Herrera OE, Moraïs S, Desai D, Amin S, Koo I, Turck CW, Mizrahi I, Kris-Etherton PM, Petersen KS, Fleming JA, Huan T, Patterson AD, Siegel D, Hagey LR, Wang M, Aron AT, Dorrestein PC. PMID: 38471500; PMCID: PMC12248420.
    View in: PubMed Mentions: 88 Fields:
    Translation:HumansAnimals
13. Reverse metabolomics for the discovery of chemical structures from humans. Nature. 2024 02; 626(7998):419-426. Gentry EC, Collins SL, Panitchpakdi M, Belda-Ferre P, Stewart AK, Carrillo Terrazas M, Lu HH, Zuffa S, Yan T, Avila-Pacheco J, Plichta DR, Aron AT, Wang M, Jarmusch AK, Hao F, Syrkin-Nikolau M, Vlamakis H, Ananthakrishnan AN, Boland BS, Hemperly A, Vande Casteele N, Gonzalez FJ, Clish CB, Xavier RJ, Chu H, Baker ES, Patterson AD, Knight R, Siegel D, Dorrestein PC. PMID: 38052229; PMCID: PMC10849969.
    View in: PubMed Mentions: 66 Fields:
    Translation:HumansAnimalsCells
14. Short synthesis of a broadly Reactive, cell permeable serine hydrolase Fluorophosphonate-Alkyne probe. Bioorg Med Chem Lett. 2023 Oct 15; 95:129434. Konduri S, Schweer J, Siegel D. PMID: 37557924.
    View in: PubMed Mentions: 2 Fields:
15. A class of anti-inflammatory lipids decrease with aging in the central nervous system. Nat Chem Biol. 2023 02; 19(2):187-197. Tan D, Konduri S, Erikci Ertunc M, Zhang P, Wang J, Chang T, Pinto AFM, Rocha A, Donaldson CJ, Vaughan JM, Ludwig RG, Willey E, Iyer M, Gray PC, Maher P, Allen NJ, Zuchero JB, Dillin A, Mori MA, Kohama SG, Siegel D, Saghatelian A. PMID: 36266352; PMCID: PMC9898107.
    View in: PubMed Mentions: 12 Fields:
    Translation:HumansAnimalsCells
16. Effects of Eupalinilide E and UM171, alone and in combination on cytokine stimulated ex-vivo expansion of human cord blood hematopoietic stem cells. Blood Cells Mol Dis. 2020 09; 84:102457. Zhang J, Huang X, Guo B, Cooper S, Capitano ML, Johnson TC, Siegel DR, Broxmeyer HE. PMID: 32604056; PMCID: PMC7942758.
    View in: PubMed Mentions: 4 Fields:
    Translation:HumansAnimalsCells
17. Pan-active imidazolopiperazine antimalarials target the Plasmodium falciparum intracellular secretory pathway. Nat Commun. 2020 04 14; 11(1):1780. LaMonte GM, Rocamora F, Marapana DS, Gnädig NF, Ottilie S, Luth MR, Worgall TS, Goldgof GM, Mohunlal R, Santha Kumar TR, Thompson JK, Vigil E, Yang J, Hutson D, Johnson T, Huang J, Williams RM, Zou BY, Cheung AL, Kumar P, Egan TJ, Lee MCS, Siegel D, Cowman AF, Fidock DA, Winzeler EA. PMID: 32286267; PMCID: PMC7156427.
    View in: PubMed Mentions: 25 Fields:
    Translation:AnimalsCells
18. Total Synthesis of Micrococcin P1 through Scalable Thiazole Forming Reactions of Cysteine Derivatives and Nitriles. Org Lett. 2020 03 20; 22(6):2365-2370. Christy MP, Johnson T, McNerlin CD, Woodard J, Nelson AT, Lim B, Hamilton TL, Freiberg KM, Siegel D. PMID: 32134277.
    View in: PubMed Mentions: 7 Fields:
19. Global chemical effects of the microbiome include new bile-acid conjugations. Nature. 2020 03; 579(7797):123-129. Quinn RA, Melnik AV, Vrbanac A, Fu T, Patras KA, Christy MP, Bodai Z, Belda-Ferre P, Tripathi A, Chung LK, Downes M, Welch RD, Quinn M, Humphrey G, Panitchpakdi M, Weldon KC, Aksenov A, da Silva R, Avila-Pacheco J, Clish C, Bae S, Mallick H, Franzosa EA, Lloyd-Price J, Bussell R, Thron T, Nelson AT, Wang M, Leszczynski E, Vargas F, Gauglitz JM, Meehan MJ, Gentry E, Arthur TD, Komor AC, Poulsen O, Boland BS, Chang JT, Sandborn WJ, Lim M, Garg N, Lumeng JC, Xavier RJ, Kazmierczak BI, Jain R, Egan M, Rhee KE, Ferguson D, Raffatellu M, Vlamakis H, Haddad GG, Siegel D, Huttenhower C, Mazmanian SK, Evans RM, Nizet V, Knight R, Dorrestein PC. PMID: 32103176; PMCID: PMC7252668.
    View in: PubMed Mentions: 304 Fields:
    Translation:HumansAnimals
20. PAHSAs enhance hepatic and systemic insulin sensitivity through direct and indirect mechanisms. J Clin Invest. 2019 10 01; 129(10):4138-4150. Zhou P, Santoro A, Peroni OD, Nelson AT, Saghatelian A, Siegel D, Kahn BB. PMID: 31449056; PMCID: PMC6763232.
    View in: PubMed Mentions: 51 Fields:
    Translation:AnimalsCells
21. Gut bacteria responding to dietary change encode sialidases that exhibit preference for red meat-associated carbohydrates. Nat Microbiol. 2019 12; 4(12):2082-2089. Zaramela LS, Martino C, Alisson-Silva F, Rees SD, Diaz SL, Chuzel L, Ganatra MB, Taron CH, Secrest P, Zuñiga C, Huang J, Siegel D, Chang G, Varki A, Zengler K. PMID: 31548686; PMCID: PMC6879853.
    View in: PubMed Mentions: 41 Fields:
    Translation:HumansAnimalsCells
22. Stereochemistry of Linoleic Acid Esters of Hydroxy Linoleic Acids. Org Lett. 2019 10 04; 21(19):8080-8084. Wang H, Kolar MJ, Chang T, Rizo J, Konduri S, McNerlin C, Saghatelian A, Siegel D. PMID: 31545060.
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23. PAHSAs attenuate immune responses and promote β cell survival in autoimmune diabetic mice. J Clin Invest. 2019 08 05; 129(9):3717-3731. Syed I, Rubin de Celis MF, Mohan JF, Moraes-Vieira PM, Vijayakumar A, Nelson AT, Siegel D, Saghatelian A, Mathis D, Kahn BB. PMID: 31380811; PMCID: PMC6715391.
    View in: PubMed Mentions: 36 Fields:
    Translation:HumansAnimalsCells
24. Linoleic acid esters of hydroxy linoleic acids are anti-inflammatory lipids found in plants and mammals. J Biol Chem. 2019 07 05; 294(27):10698-10707. Kolar MJ, Konduri S, Chang T, Wang H, McNerlin C, Ohlsson L, Härröd M, Siegel D, Saghatelian A. PMID: 31152059; PMCID: PMC6615670.
    View in: PubMed Mentions: 43 Fields:
    Translation:HumansAnimalsCells
25. Discovery of FAHFA-Containing Triacylglycerols and Their Metabolic Regulation. J Am Chem Soc. 2019 06 05; 141(22):8798-8806. Tan D, Ertunc ME, Konduri S, Zhang J, Pinto AM, Chu Q, Kahn BB, Siegel D, Saghatelian A. PMID: 31056915; PMCID: PMC6662584.
    View in: PubMed Mentions: 34 Fields:
    Translation:AnimalsCells
26. Synthesis of chemically edited derivatives of the endogenous regulator of inflammation 9-PAHSA. J Antibiot (Tokyo). 2019 06; 72(6):498-506. Wang H, Chang T, Konduri S, Huang J, Saghatelian A, Siegel D. PMID: 30988370; PMCID: PMC6784544.
    View in: PubMed Mentions: 3 Fields:
    Translation:AnimalsCells
27. Metal-Binding Pharmacophore Library Yields the Discovery of a Glyoxalase 1 Inhibitor. J Med Chem. 2019 02 14; 62(3):1609-1625. Perez C, Barkley-Levenson AM, Dick BL, Glatt PF, Martinez Y, Siegel D, Momper JD, Palmer AA, Cohen SM. PMID: 30628789; PMCID: PMC6467756.
    View in: PubMed Mentions: 16 Fields:
    Translation:HumansAnimalsCells
28. Open-source discovery of chemical leads for next-generation chemoprotective antimalarials. Science. 2018 12 07; 362(6419). Antonova-Koch Y, Meister S, Abraham M, Luth MR, Ottilie S, Lukens AK, Sakata-Kato T, Vanaerschot M, Owen E, Jado JC, Maher SP, Calla J, Plouffe D, Zhong Y, Chen K, Chaumeau V, Conway AJ, McNamara CW, Ibanez M, Gagaring K, Serrano FN, Eribez K, Taggard CM, Cheung AL, Lincoln C, Ambachew B, Rouillier M, Siegel D, Nosten F, Kyle DE, Gamo FJ, Zhou Y, Llinás M, Fidock DA, Wirth DF, Burrows J, Campo B, Winzeler EA. PMID: 30523084; PMCID: PMC6516198.
    View in: PubMed Mentions: 75 Fields:
    Translation:HumansAnimalsCells
29. Faster Protocol for Endogenous Fatty Acid Esters of Hydroxy Fatty Acid (FAHFA) Measurements. Anal Chem. 2018 04 17; 90(8):5358-5365. Kolar MJ, Nelson AT, Chang T, Ertunc ME, Christy MP, Ohlsson L, Härröd M, Kahn BB, Siegel D, Saghatelian A. PMID: 29578702; PMCID: PMC5962352.
    View in: PubMed Mentions: 19 Fields:
    Translation:Cells
30. In Vitro Efficacy of Ebselen and BAY 11-7082 Against Naegleria fowleri. Front Microbiol. 2018; 9:414. Debnath A, Nelson AT, Silva-Olivares A, Shibayama M, Siegel D, McKerrow JH. PMID: 29559968; PMCID: PMC5845744.
    View in: PubMed Mentions: 24
31. Palmitic Acid Hydroxystearic Acids Activate GPR40, Which Is Involved in Their Beneficial Effects on Glucose Homeostasis. Cell Metab. 2018 02 06; 27(2):419-427.e4. Syed I, Lee J, Moraes-Vieira PM, Donaldson CJ, Sontheimer A, Aryal P, Wellenstein K, Kolar MJ, Nelson AT, Siegel D, Mokrosinski J, Farooqi IS, Zhao JJ, Yore MM, Peroni OD, Saghatelian A, Kahn BB. PMID: 29414687; PMCID: PMC5807007.
    View in: PubMed Mentions: 89 Fields:
    Translation:HumansAnimalsCells
32. Mapping the malaria parasite druggable genome by using in vitro evolution and chemogenomics. Science. 2018 01 12; 359(6372):191-199. Cowell AN, Istvan ES, Lukens AK, Gomez-Lorenzo MG, Vanaerschot M, Sakata-Kato T, Flannery EL, Magistrado P, Owen E, Abraham M, LaMonte G, Painter HJ, Williams RM, Franco V, Linares M, Arriaga I, Bopp S, Corey VC, Gnädig NF, Coburn-Flynn O, Reimer C, Gupta P, Murithi JM, Moura PA, Fuchs O, Sasaki E, Kim SW, Teng CH, Wang LT, Akidil A, Adjalley S, Willis PA, Siegel D, Tanaseichuk O, Zhong Y, Zhou Y, Llinás M, Ottilie S, Gamo FJ, Lee MCS, Goldberg DE, Fidock DA, Wirth DF, Winzeler EA. PMID: 29326268; PMCID: PMC5925756.
    View in: PubMed Mentions: 148 Fields:
    Translation:Animals
33. Directing Stem Cell Fate: The Synthetic Natural Product Connection. Chem Rev. 2017 Sep 27; 117(18):12052-12086. Johnson TC, Siegel D. PMID: 28771328.
    View in: PubMed Mentions: 9 Fields:
    Translation:HumansCells
34. Synthetic Route Development for the Laboratory Preparation of Eupalinilide E. J Org Chem. 2017 05 05; 82(9):4640-4653. Johnson TC, Chin MR, Siegel D. PMID: 28440078.
    View in: PubMed Mentions: 4 Fields:
    Translation:Cells
35. Stereochemistry of Endogenous Palmitic Acid Ester of 9-Hydroxystearic Acid and Relevance of Absolute Configuration to Regulation. J Am Chem Soc. 2017 04 05; 139(13):4943-4947. Nelson AT, Kolar MJ, Chu Q, Syed I, Kahn BB, Saghatelian A, Siegel D. PMID: 28350171; PMCID: PMC5568760.
    View in: PubMed Mentions: 25 Fields:
    Translation:HumansAnimalsCells
36. Synthesis of Eupalinilide E, a Promoter of Human Hematopoietic Stem and Progenitor Cell Expansion. J Am Chem Soc. 2016 05 11; 138(18):6068-73. Johnson TC, Chin MR, Han T, Shen JP, Rana T, Siegel D. PMID: 27096704.
    View in: PubMed Mentions: 8 Fields:
    Translation:HumansCells
37. Evaluation of pentacyclic triterpenes found in Perilla frutescens for inhibition of skin tumor promotion by 12-O-tetradecanoylphorbol-13-acetate. Oncotarget. 2015 Nov 17; 6(36):39292-306. Cho J, Tremmel L, Rho O, Camelio AM, Siegel D, Slaga TJ, DiGiovanni J. PMID: 26513295; PMCID: PMC4770773.
    View in: PubMed Mentions: 7 Fields:
    Translation:AnimalsCells
38. Total Synthesis of Celastrol, Development of a Platform to Access Celastroid Natural Products. J Am Chem Soc. 2015 Sep 23; 137(37):11864-7. Camelio AM, Johnson TC, Siegel D. PMID: 26331410.
    View in: PubMed Mentions: 12 Fields:
39. Dearomatization Reactions Using Phthaloyl Peroxide. Org Lett. 2015 Sep 18; 17(18):4420-3. Eliasen AM, Christy M, Claussen KR, Besandre R, Thedford RP, Siegel D. PMID: 26333308.
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40. Computational and Experimental Studies of Phthaloyl Peroxide-Mediated Hydroxylation of Arenes Yield a More Reactive Derivative, 4,5-Dichlorophthaloyl Peroxide. J Org Chem. 2015 Aug 21; 80(16):8084-95. Camelio AM, Liang Y, Eliasen AM, Johnson TC, Yuan C, Schuppe AW, Houk KN, Siegel D. PMID: 26200205.
    View in: PubMed Mentions: 7 Fields:
    Translation:Cells
41. Synthesis of oxygenated oleanolic and ursolic acid derivatives with anti-inflammatory properties. Bioorg Med Chem Lett. 2015 Oct 01; 25(19):4342-6. Nelson AT, Camelio AM, Claussen KR, Cho J, Tremmel L, DiGiovanni J, Siegel D. PMID: 26259803; PMCID: PMC4835183.
    View in: PubMed Mentions: 13 Fields:
    Translation:AnimalsCells
42. Effect of Combined Treatment with Ursolic Acid and Resveratrol on Skin Tumor Promotion by 12-O-Tetradecanoylphorbol-13-Acetate. Cancer Prev Res (Phila). 2015 Sep; 8(9):817-25. Cho J, Rho O, Junco J, Carbajal S, Siegel D, Slaga TJ, DiGiovanni J. PMID: 26100520; PMCID: PMC4560654.
    View in: PubMed Mentions: 25 Fields:
    Translation:AnimalsCells
43. Expedited access to vinaxanthone and chemically edited derivatives possessing neuronal regenerative effects through ynone coupling reactions. ACS Chem Neurosci. 2015 Apr 15; 6(4):542-50. Chin MR, Zlotkowski K, Han M, Patel S, Eliasen AM, Axelrod A, Siegel D. PMID: 25615693.
    View in: PubMed Mentions: 7 Fields:
    Translation:AnimalsCells
44. Semaphorin3a promotes advanced diabetic nephropathy. Diabetes. 2015 May; 64(5):1743-59. Aggarwal PK, Veron D, Thomas DB, Siegel D, Moeckel G, Kashgarian M, Tufro A. PMID: 25475434; PMCID: PMC4407856.
    View in: PubMed Mentions: 32 Fields:
    Translation:HumansAnimalsCells
45. Preparation of phenols by phthaloyl peroxide-mediated oxidation of arenes. Nat Protoc. 2014 Nov; 9(11):2624-9. Yuan C, Eliasen AM, Camelio AM, Siegel D. PMID: 25321407.
    View in: PubMed Mentions: 3 Fields:
    Translation:Cells
46. A protocol to generate phthaloyl peroxide in flow for the hydroxylation of arenes. Org Lett. 2014 Jul 18; 16(14):3628-31. Eliasen AM, Thedford RP, Claussen KR, Yuan C, Siegel D. PMID: 24988535.
    View in: PubMed Mentions: 2 Fields:
    Translation:Cells
47. Complanadine A, a selective agonist for the Mas-related G protein-coupled receptor X2. Bioorg Med Chem Lett. 2014 Aug 01; 24(15):3512-5. Johnson T, Siegel D. PMID: 24930830.
    View in: PubMed Mentions: 8 Fields:
    Translation:HumansCells
48. Small-molecule mechanism of action studies in Caenorhabditis elegans. Chembiochem. 2013 Nov 25; 14(17):2338-44. Zlotkowski K, Eliasen AM, Mitra A, Siegel D. PMID: 24123757.
    View in: PubMed Mentions: 1 Fields:
    Translation:Animals
49. Metal-free oxidation of aromatic carbon-hydrogen bonds through a reverse-rebound mechanism. Nature. 2013 Jul 11; 499(7457):192-6. Yuan C, Liang Y, Hernandez T, Berriochoa A, Houk KN, Siegel D. PMID: 23846658.
    View in: PubMed Mentions: 35 Fields:
    Translation:Cells
50. Syntheses of (+)-complanadine A and lycodine derivatives by regioselective [2 + 2 + 2] cycloadditions. J Org Chem. 2013 Jun 07; 78(11):5647-68. Yuan C, Chang CT, Siegel D. PMID: 23635039.
    View in: PubMed Mentions: 5 Fields:
    Translation:Cells
51. Small-molecule-mediated axonal branching in Caenorhabditis elegans. Chembiochem. 2013 Feb 11; 14(3):307-10. Zlotkowski K, Pierce-Shimomura J, Siegel D. PMID: 23362121; PMCID: PMC4470382.
    View in: PubMed Mentions: 3 Fields:
    Translation:AnimalsCells
52. Syntheses of xanthofulvin and vinaxanthone, natural products enabling spinal cord regeneration. Angew Chem Int Ed Engl. 2013 Mar 18; 52(12):3421-4. Axelrod A, Eliasen AM, Chin MR, Zlotkowski K, Siegel D. PMID: 23086682.
    View in: PubMed Mentions: 6 Fields:
    Translation:AnimalsCells
53. Neuronal growth promoting sesquiterpene-neolignans; syntheses and biological studies. Org Biomol Chem. 2012 Jan 14; 10(2):383-93. Cheng X, Harzdorf N, Khaing Z, Kang D, Camelio AM, Shaw T, Schmidt CE, Siegel D. PMID: 22083452.
    View in: PubMed Mentions: 10 Fields:
    Translation:AnimalsCells
54. Employing modular polyketide synthase ketoreductases as biocatalysts in the preparative chemoenzymatic syntheses of diketide chiral building blocks. Chem Biol. 2011 Oct 28; 18(10):1331-40. Piasecki SK, Taylor CA, Detelich JF, Liu J, Zheng J, Komsoukaniants A, Siegel DR, Keatinge-Clay AT. PMID: 22035802.
    View in: PubMed Mentions: 41 Fields:
    Translation:Cells
55. Caenorhabditis elegans selects distinct crawling and swimming gaits via dopamine and serotonin. Proc Natl Acad Sci U S A. 2011 Oct 18; 108(42):17504-9. Vidal-Gadea A, Topper S, Young L, Crisp A, Kressin L, Elbel E, Maples T, Brauner M, Erbguth K, Axelrod A, Gottschalk A, Siegel D, Pierce-Shimomura JT. PMID: 21969584; PMCID: PMC3198358.
    View in: PubMed Mentions: 95 Fields:
    Translation:AnimalsCells
56. Hippocampal and cortical neuronal growth mediated by the small molecule natural product clovanemagnolol. Bioorg Med Chem Lett. 2011 Aug 15; 21(16):4808-12. Khaing Z, Kang D, Camelio AM, Schmidt CE, Siegel D. PMID: 21757342.
    View in: PubMed Mentions: 6 Fields:
    Translation:AnimalsCells
57. Selective inactivation of a human neuronal silencing phosphatase by a small molecule inhibitor. ACS Chem Biol. 2011 May 20; 6(5):511-9. Zhang M, Cho EJ, Burstein G, Siegel D, Zhang Y. PMID: 21348431; PMCID: PMC4814157.
    View in: PubMed Mentions: 19 Fields:
    Translation:HumansCells
58. Hydroxyl-directed cyclizations of 1,6-enynes. Org Lett. 2011 Mar 18; 13(6):1517-9. Camelio AM, Barton T, Guo F, Shaw T, Siegel D. PMID: 21314167.
    View in: PubMed Mentions: 5 Fields:
    Translation:Cells
59. Synthesis of (+)-complanadine A, an inducer of neurotrophic factor excretion. J Am Chem Soc. 2010 May 05; 132(17):5924-5. Yuan C, Chang CT, Axelrod A, Siegel D. PMID: 20387896.
    View in: PubMed Mentions: 18 Fields:
    Translation:AnimalsCells
60. Biomimetic syntheses of the neurotrophic natural products caryolanemagnolol and clovanemagnolol. Org Lett. 2010 Mar 19; 12(6):1304-7. Cheng X, Harzdorf NL, Shaw T, Siegel D. PMID: 20158263.
    View in: PubMed Mentions: 9 Fields:
    Translation:Cells
61. A robust platform for the synthesis of new tetracycline antibiotics. J Am Chem Soc. 2008 Dec 31; 130(52):17913-27. Sun C, Wang Q, Brubaker JD, Wright PM, Lerner CD, Noson K, Charest M, Siegel DR, Wang YM, Myers AG. PMID: 19053822; PMCID: PMC2681267.
    View in: PubMed Mentions: 37 Fields:
    Translation:HumansAnimalsCells
62. Differentiation of nonconventional "carbanions"-the total synthesis of nemorosone and clusianone. Angew Chem Int Ed Engl. 2007; 46(46):8840-4. Tsukano C, Siegel DR, Danishefsky SJ. PMID: 17935090.
    View in: PubMed Mentions: 18 Fields:
    Translation:Cells
63. Studies directed toward the synthesis of terreulactone A: rapid construction of the A, B, C rings. Org Lett. 2006 Feb 02; 8(3):423-5. Liu H, Siegel DR, Danishefsky SJ. PMID: 16435850.
    View in: PubMed Mentions: 4 Fields:
    Translation:AnimalsCells
64. Total synthesis of garsubellin A. J Am Chem Soc. 2006 Feb 01; 128(4):1048-9. Siegel DR, Danishefsky SJ. PMID: 16433500.
    View in: PubMed Mentions: 22 Fields:
    Translation:Animals
65. Synthesis of (-)-tetracycline. J Am Chem Soc. 2005 Jun 15; 127(23):8292-3. Charest MG, Siegel DR, Myers AG. PMID: 15941256.
    View in: PubMed Mentions: 23 Fields:
66. A convergent enantioselective route to structurally diverse 6-deoxytetracycline antibiotics. Science. 2005 Apr 15; 308(5720):395-8. Charest MG, Lerner CD, Brubaker JD, Siegel DR, Myers AG. PMID: 15831754.
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    Translation:Cells
67. Synthesis of a broad array of highly functionalized, enantiomerically pure cyclohexanecarboxylic acid derivatives by microbial dihydroxylation of benzoic acid and subsequent oxidative and rearrangement reactions. Org Lett. 2001 Sep 06; 3(18):2923-6. Myers AG, Siegel DR, Buzard DJ, Charest MG. PMID: 11529791.
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