Ciprian Iliescu | University Politehnica of Bucharest (original) (raw)

Papers by Ciprian Iliescu

Research paper thumbnail of Microfluidic Device for Continuous Magnetophoretic Separation of Red Blood Cells

HAL (Le Centre pour la Communication Scientifique Directe), Apr 1, 2008

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Research paper thumbnail of Microfluidic device for continuous magnetophoretic separation of red blood cells

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Research paper thumbnail of A Comprehensive Review on Thin Film Depositions on Pecvd Reactors

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Research paper thumbnail of Rapid Enhancement of Cellular Spheroid Assembly by Acoustically Driven Microcentrifugation

ACS Biomaterials Science & Engineering, 2016

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Research paper thumbnail of Magnetic field distribution for weak-, strong- and FFAG-focusing particle accelerators and other nuclear instruments

Nuclear Instruments and Methods, 1963

For the magnetic guiding field of the weak-, strong-, and FFAG-focusing ; nuclear instruments use... more For the magnetic guiding field of the weak-, strong-, and FFAG-focusing ; nuclear instruments used in the acceleration or dispersion of charged particles, ; general analytic expressions, valid for any point of the magnet gap, are derived ; concerning the following parameters: magnetic scalar potential, magnetic ; induction, and magnetic vector potential. These expressions are useful for the ; study of particle motion as well as for pole face design. (auth);

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Research paper thumbnail of SARS-CoV-2: From Structure to Pathology, Host Immune Response and Therapeutic Management

Microorganisms, 2020

Coronaviruses are large, enveloped viruses with a single-stranded RNA genome, infecting both huma... more Coronaviruses are large, enveloped viruses with a single-stranded RNA genome, infecting both humans and a wide range of wild and domestic animals. SARS-CoV-2, the agent of the COVID-19 pandemic, has 80% sequence homology with SARS-CoV-1 and 96–98% homology with coronaviruses isolated from bats. The spread of infection is favored by prolonged exposure to high densities of aerosols indoors. Current studies have shown that SARS-CoV-2 is much more stable than other coronaviruses and viral respiratory pathogens. The severe forms of infection are associated with several risk factors, including advanced age, metabolic syndrome, diabetes, obesity, chronic inflammatory or autoimmune disease, and other preexisting infectious diseases, all having in common the pre-existence of a pro-inflammatory condition. Consequently, it is essential to understand the relationship between the inflammatory process and the specific immune response in SARS-CoV-2 infection. In this review, we present a general c...

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Research paper thumbnail of IoT PCR for pandemic disease detection and its spread monitoring

Sensors and Actuators B-chemical, 2020

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Research paper thumbnail of Antiviral Immunity in SARS-CoV-2 Infection: From Protective to Deleterious Responses

Microorganisms, Dec 13, 2021

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Research paper thumbnail of Early Notice Pointer, an IoT-like Platform for Point-of-Care Feet and Body Balance Screening

Micromachines, Apr 27, 2022

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Research paper thumbnail of Theoretical Analysis and Experiment of a Novel Dep Chip with 3-D Silicon Electrodes

International Journal of Software Engineering and Knowledge Engineering, Apr 1, 2005

This paper presents a novel dielectrophoresis (DEP) device where the DEP electrodes define the ch... more This paper presents a novel dielectrophoresis (DEP) device where the DEP electrodes define the channel walls. This is achieved by fabricating microfluidic channel walls from highly doped silicon so that they can also function as DEP electrodes. Compared with planar electrodes, this device increases the exhibited dielectrophoretic force on the particle, therefore decreases the applied potential and reduces the heating of the solution. A DEP device with triangle electrodes has been designed and fabricated. Compared with the other two configurations, semi-circular and square, triangle electrode presents an increased force, which can decrease the applied voltage and reduce the Joule effect. Yeast cells have been used to for testing the performance of the device.

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Research paper thumbnail of A vascular-liver chip for sensitive detection of nutraceutical metabolites from human pluripotent stem cell derivatives

Biomicrofluidics, May 1, 2020

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Research paper thumbnail of A new fabrication method of low stress PECVD SiNx layers for biomedical applications

Thin Solid Films, Jun 1, 2008

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Research paper thumbnail of Thick and low-stress PECVD amorphous silicon for MEMS applications

Journal of Micromechanics and Microengineering, Dec 11, 2007

ABSTRACT This paper presents a solution for the deposition of thick amorphous silicon (alpha-Si:H... more ABSTRACT This paper presents a solution for the deposition of thick amorphous silicon (alpha-Si:H) in PECVD reactors for MEMS applications, such as sacrificial layer or mask layer for dry or wet etching of glass. This achievement was possible by tuning the deposition parameters to a 'zero' value of the residual stress in the a-Si: H layer. The influence of the process parameters, such as power, frequency mode, temperature, pressure and SiH(4)/Ar flow rates for tuning the residual stress and for a good deposition rate is analyzed. The deposition of low-stress and thick (more than 12 mu m in our case) alpha-Si:H layers was possible without generation of hillock defects (previously reported in literature for layers thicker then 2 mu m). Finally, the paper presents some MEMS applications of such a deposited alpha-Si: H layer: masking layer for deep wet etching as well as dry etching of glass, and sacrificial layer for dry or wet release.

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Research paper thumbnail of In Vivo Experimental Study of Noninvasive Insulin Microinjection through Hollow Si Microneedle Array

Micromachines, Jan 20, 2018

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Research paper thumbnail of A microfluidic device for impedance spectroscopy analysis of biological samples

Sensors and Actuators B-chemical, Apr 10, 2007

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Research paper thumbnail of Defect-free wet etching through pyrex glass using Cr/Au mask

Microsystem Technologies-micro-and Nanosystems-information Storage and Processing Systems, Mar 7, 2006

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Research paper thumbnail of Fabrication of a dielectrophoretic chip with 3D silicon electrodes

Journal of Micromechanics and Microengineering, Dec 17, 2004

This paper describes a device in which the DEP electrodes form the channel walls. This is achieve... more This paper describes a device in which the DEP electrodes form the channel walls. This is achieved by fabricating microfluidic channel walls from highly doped silicon so that they can also function as DEP electrodes. The device is fully enclosed and there is no fluidic ...

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Research paper thumbnail of Cell Culture on MEMS Platforms: A Review

International Journal of Molecular Sciences, Dec 18, 2009

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Research paper thumbnail of Manipulation of Biological Samples using Electric Field

CAS ... proceedings, Oct 1, 2007

The paper presents original contributions at manipulation of biological samples using electric fi... more The paper presents original contributions at manipulation of biological samples using electric field (dielectrophoresis). Design considerations, fabrication processes and experimental results of three original three dimensional (3D) dielectrophoretic (DEP) structures: DEP chip with 3D silicon electrodes, DEP chip with 3D electric field gradient and 3D filtering chip are analyzed. The paper presents also the experimental results of trapping yeast cells.

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Research paper thumbnail of A new fabrication process of silicon nanotips: NERCOM

Proceedings of SPIE, Dec 28, 2005

This paper presents a new fabrication process for nanotips array using notching effect of reflect... more This paper presents a new fabrication process for nanotips array using notching effect of reflected charges on mask (NERCOM). The NERCOM fabrication process is based on two phenomena: flowing of thick photoresist mask after bake and the notching effect of the reflected charges from the photoresist mask in a plasma etching process. Heating the photoresist at different temperature and time will generate different profile of the masking layer walls. During the plasma etching process, the charges (ions and radicals) are reflected by the oblique profile of the masking layer walls and generate an undercut. This phenomenon is utilized with an isotropic etching process in a Deep RIE system to produce tips. Due to the isotropy of the process, the tips are generated. The results indicate that the radii of the tips are in the range of 40 to 60 nm.

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Research paper thumbnail of Microfluidic Device for Continuous Magnetophoretic Separation of Red Blood Cells

HAL (Le Centre pour la Communication Scientifique Directe), Apr 1, 2008

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Research paper thumbnail of Microfluidic device for continuous magnetophoretic separation of red blood cells

Bookmarks Related papers MentionsView impact

Research paper thumbnail of A Comprehensive Review on Thin Film Depositions on Pecvd Reactors

Bookmarks Related papers MentionsView impact

Research paper thumbnail of Rapid Enhancement of Cellular Spheroid Assembly by Acoustically Driven Microcentrifugation

ACS Biomaterials Science & Engineering, 2016

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Research paper thumbnail of Magnetic field distribution for weak-, strong- and FFAG-focusing particle accelerators and other nuclear instruments

Nuclear Instruments and Methods, 1963

For the magnetic guiding field of the weak-, strong-, and FFAG-focusing ; nuclear instruments use... more For the magnetic guiding field of the weak-, strong-, and FFAG-focusing ; nuclear instruments used in the acceleration or dispersion of charged particles, ; general analytic expressions, valid for any point of the magnet gap, are derived ; concerning the following parameters: magnetic scalar potential, magnetic ; induction, and magnetic vector potential. These expressions are useful for the ; study of particle motion as well as for pole face design. (auth);

Bookmarks Related papers MentionsView impact

Research paper thumbnail of SARS-CoV-2: From Structure to Pathology, Host Immune Response and Therapeutic Management

Microorganisms, 2020

Coronaviruses are large, enveloped viruses with a single-stranded RNA genome, infecting both huma... more Coronaviruses are large, enveloped viruses with a single-stranded RNA genome, infecting both humans and a wide range of wild and domestic animals. SARS-CoV-2, the agent of the COVID-19 pandemic, has 80% sequence homology with SARS-CoV-1 and 96–98% homology with coronaviruses isolated from bats. The spread of infection is favored by prolonged exposure to high densities of aerosols indoors. Current studies have shown that SARS-CoV-2 is much more stable than other coronaviruses and viral respiratory pathogens. The severe forms of infection are associated with several risk factors, including advanced age, metabolic syndrome, diabetes, obesity, chronic inflammatory or autoimmune disease, and other preexisting infectious diseases, all having in common the pre-existence of a pro-inflammatory condition. Consequently, it is essential to understand the relationship between the inflammatory process and the specific immune response in SARS-CoV-2 infection. In this review, we present a general c...

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Research paper thumbnail of IoT PCR for pandemic disease detection and its spread monitoring

Sensors and Actuators B-chemical, 2020

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Research paper thumbnail of Antiviral Immunity in SARS-CoV-2 Infection: From Protective to Deleterious Responses

Microorganisms, Dec 13, 2021

Bookmarks Related papers MentionsView impact

Research paper thumbnail of Early Notice Pointer, an IoT-like Platform for Point-of-Care Feet and Body Balance Screening

Micromachines, Apr 27, 2022

Bookmarks Related papers MentionsView impact

Research paper thumbnail of Theoretical Analysis and Experiment of a Novel Dep Chip with 3-D Silicon Electrodes

International Journal of Software Engineering and Knowledge Engineering, Apr 1, 2005

This paper presents a novel dielectrophoresis (DEP) device where the DEP electrodes define the ch... more This paper presents a novel dielectrophoresis (DEP) device where the DEP electrodes define the channel walls. This is achieved by fabricating microfluidic channel walls from highly doped silicon so that they can also function as DEP electrodes. Compared with planar electrodes, this device increases the exhibited dielectrophoretic force on the particle, therefore decreases the applied potential and reduces the heating of the solution. A DEP device with triangle electrodes has been designed and fabricated. Compared with the other two configurations, semi-circular and square, triangle electrode presents an increased force, which can decrease the applied voltage and reduce the Joule effect. Yeast cells have been used to for testing the performance of the device.

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Research paper thumbnail of A vascular-liver chip for sensitive detection of nutraceutical metabolites from human pluripotent stem cell derivatives

Biomicrofluidics, May 1, 2020

Bookmarks Related papers MentionsView impact

Research paper thumbnail of A new fabrication method of low stress PECVD SiNx layers for biomedical applications

Thin Solid Films, Jun 1, 2008

Bookmarks Related papers MentionsView impact

Research paper thumbnail of Thick and low-stress PECVD amorphous silicon for MEMS applications

Journal of Micromechanics and Microengineering, Dec 11, 2007

ABSTRACT This paper presents a solution for the deposition of thick amorphous silicon (alpha-Si:H... more ABSTRACT This paper presents a solution for the deposition of thick amorphous silicon (alpha-Si:H) in PECVD reactors for MEMS applications, such as sacrificial layer or mask layer for dry or wet etching of glass. This achievement was possible by tuning the deposition parameters to a 'zero' value of the residual stress in the a-Si: H layer. The influence of the process parameters, such as power, frequency mode, temperature, pressure and SiH(4)/Ar flow rates for tuning the residual stress and for a good deposition rate is analyzed. The deposition of low-stress and thick (more than 12 mu m in our case) alpha-Si:H layers was possible without generation of hillock defects (previously reported in literature for layers thicker then 2 mu m). Finally, the paper presents some MEMS applications of such a deposited alpha-Si: H layer: masking layer for deep wet etching as well as dry etching of glass, and sacrificial layer for dry or wet release.

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Research paper thumbnail of In Vivo Experimental Study of Noninvasive Insulin Microinjection through Hollow Si Microneedle Array

Micromachines, Jan 20, 2018

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Research paper thumbnail of A microfluidic device for impedance spectroscopy analysis of biological samples

Sensors and Actuators B-chemical, Apr 10, 2007

Bookmarks Related papers MentionsView impact

Research paper thumbnail of Defect-free wet etching through pyrex glass using Cr/Au mask

Microsystem Technologies-micro-and Nanosystems-information Storage and Processing Systems, Mar 7, 2006

Bookmarks Related papers MentionsView impact

Research paper thumbnail of Fabrication of a dielectrophoretic chip with 3D silicon electrodes

Journal of Micromechanics and Microengineering, Dec 17, 2004

This paper describes a device in which the DEP electrodes form the channel walls. This is achieve... more This paper describes a device in which the DEP electrodes form the channel walls. This is achieved by fabricating microfluidic channel walls from highly doped silicon so that they can also function as DEP electrodes. The device is fully enclosed and there is no fluidic ...

Bookmarks Related papers MentionsView impact

Research paper thumbnail of Cell Culture on MEMS Platforms: A Review

International Journal of Molecular Sciences, Dec 18, 2009

Bookmarks Related papers MentionsView impact

Research paper thumbnail of Manipulation of Biological Samples using Electric Field

CAS ... proceedings, Oct 1, 2007

The paper presents original contributions at manipulation of biological samples using electric fi... more The paper presents original contributions at manipulation of biological samples using electric field (dielectrophoresis). Design considerations, fabrication processes and experimental results of three original three dimensional (3D) dielectrophoretic (DEP) structures: DEP chip with 3D silicon electrodes, DEP chip with 3D electric field gradient and 3D filtering chip are analyzed. The paper presents also the experimental results of trapping yeast cells.

Bookmarks Related papers MentionsView impact

Research paper thumbnail of A new fabrication process of silicon nanotips: NERCOM

Proceedings of SPIE, Dec 28, 2005

This paper presents a new fabrication process for nanotips array using notching effect of reflect... more This paper presents a new fabrication process for nanotips array using notching effect of reflected charges on mask (NERCOM). The NERCOM fabrication process is based on two phenomena: flowing of thick photoresist mask after bake and the notching effect of the reflected charges from the photoresist mask in a plasma etching process. Heating the photoresist at different temperature and time will generate different profile of the masking layer walls. During the plasma etching process, the charges (ions and radicals) are reflected by the oblique profile of the masking layer walls and generate an undercut. This phenomenon is utilized with an isotropic etching process in a Deep RIE system to produce tips. Due to the isotropy of the process, the tips are generated. The results indicate that the radii of the tips are in the range of 40 to 60 nm.

Bookmarks Related papers MentionsView impact