Immediate effect of acupuncture at Sanyinjiao (SP6) and Xuanzhong (GB39) on uterine arterial blood flow in primary dysmenorrhea - PubMed (original) (raw)
Randomized Controlled Trial
. 2010 Oct;16(10):1073-8.
doi: 10.1089/acm.2009.0326. Epub 2010 Oct 9.
Affiliations
- PMID: 20932189
- DOI: 10.1089/acm.2009.0326
Randomized Controlled Trial
Immediate effect of acupuncture at Sanyinjiao (SP6) and Xuanzhong (GB39) on uterine arterial blood flow in primary dysmenorrhea
Yan-Pu Yu et al. J Altern Complement Med. 2010 Oct.
Abstract
Objective: The objective of this study was to compare immediate effect of acupuncture at SP6 on uterine arterial blood flow in primary dysmenorrhea with that of GB39.
Design: This was a prospective, randomized clinical trial.
Setting: Sixty-six (66) patients with primary dysmenorrhea from the Affiliated Hospital of Shangdong University of Traditional Chinese Medicine were recruited.
Interventions: The SP6 group (n =32) was treated with manual acupuncture at bilateral SP6 for 5 minutes after obtaining needling sensation (de qi) during the period of menstrual pain, whereas the control group (n = 34) was needled at GB39 of both sides for 5 minutes when they suffered menstrual pain.
Main outcome measures: Differences in pulsatility index (PI), resistance index (RI), and ratio of systolic peak and diastolic peak (A/B) in uterine arteries were the main outcome measures.
Results: Highly significant reductions were observed in the SP6 treatment group 5 minutes after treatment in menstrual pain scores (8.17 ± 1.90 versus 11.20 ± 2.66; p < 0.001), values of PI (1.75 ± 0.48 versus 2.32 ± 0.70; p < 0.001), RI (0.72 ± 0.11 versus 0.78 ± 0.07; p < 0.001), and A/B (4.33 ± 1.37 versus 5.23 ± 1.67; p < 0.001). Compared with the GB39 control group, patients in the SP6 treatment group showed significant reductions in 5 minutes after treatment in the changes of menstrual pain scores (3.03 ± 2.36 versus 0.00 ± 0.29; p < 0.001), values of PI (0.57 ± 0.42 versus -0.10 ± 0.58; p < 0.001), RI (0.06 ± 0.08 versus -0.03 ± 0.15; p < 0.01), and A/B (0.90 ± 0.87 versus 0.23 ± 1.02; p < 0.01). There were no significant changes in menstrual pain scores, values of PI, RI, or A/B before and after treatment in the GB39 control group (p > 0.05). No adverse events from treatment were reported.
Conclusions: This study suggests that needling at SP6 can immediately improve uterine arterial blood flow of patients with primary dysmenorrhea, while GB39 does not have these effects.
Similar articles
- A comparative study on the immediate effects of electroacupuncture at Sanyinjiao (SP6), Xuanzhong (GB39) and a non-meridian point, on menstrual pain and uterine arterial blood flow, in primary dysmenorrhea patients.
Ma YX, Ma LX, Liu XL, Ma YX, Lv K, Wang D, Liu JP, Xing JM, Cao HJ, Gao SZ, Zhu J. Ma YX, et al. Pain Med. 2010 Oct;11(10):1564-75. doi: 10.1111/j.1526-4637.2010.00949.x. Epub 2010 Sep 7. Pain Med. 2010. PMID: 21199306 Clinical Trial. - A randomized controlled trial of single point acupuncture in primary dysmenorrhea.
Liu CZ, Xie JP, Wang LP, Liu YQ, Song JS, Chen YY, Shi GX, Zhou W, Gao SZ, Li SL, Xing JM, Ma LX, Wang YX, Zhu J, Liu JP. Liu CZ, et al. Pain Med. 2014 Jun;15(6):910-20. doi: 10.1111/pme.12392. Epub 2014 Mar 17. Pain Med. 2014. PMID: 24636695 Clinical Trial. - Does Traditional Chinese Medicine pattern affect acupoint specific effect? Analysis of data from a multicenter, randomized, controlled trial for primary dysmenorrhea.
Liu YQ, Ma LX, Xing JM, Cao HJ, Wang YX, Tang L, Li M, Wang Y, Liang Y, Pu LY, Yu XM, Guo LZ, Jin JL, Wang Z, Ju HM, Jiang YM, Liu JJ, Yuan HW, Li CH, Zhang P, She YF, Liu JP, Zhu J. Liu YQ, et al. J Altern Complement Med. 2013 Jan;19(1):43-9. doi: 10.1089/acm.2011.0404. Epub 2012 Jul 23. J Altern Complement Med. 2013. PMID: 22823583 Clinical Trial. - Effectiveness of SP6 (Sanyinjiao) acupressure for relief of primary dysmenorrhea symptoms: A systematic review with meta- and sensitivity analyses.
Abaraogu UO, Igwe SE, Tabansi-Ochiogu CS. Abaraogu UO, et al. Complement Ther Clin Pract. 2016 Nov;25:92-105. doi: 10.1016/j.ctcp.2016.09.003. Epub 2016 Sep 9. Complement Ther Clin Pract. 2016. PMID: 27863617 Review. - Effects of moxibustion or acupoint therapy for the treatment of primary dysmenorrhea: a meta-analysis.
Xu T, Hui L, Juan YL, Min SG, Hua WT. Xu T, et al. Altern Ther Health Med. 2014 Jul-Aug;20(4):33-42. Altern Ther Health Med. 2014. PMID: 25141361 Review.
Cited by
- Influence of the Intensity, Components, and Spreading of the Deqi Sensation on the Analgesic Effect of SP6 Needling in Primary Dysmenorrhea Patients: A Secondary Analysis of a Randomised Controlled Trial.
Hu NJ, Liu YQ, Zhao MY, Wang P, Wu GW, Hu SQ, Sun JJ, Wang YF, Zhang Z, Ma LX, Zhu J. Hu NJ, et al. Evid Based Complement Alternat Med. 2019 May 16;2019:6462576. doi: 10.1155/2019/6462576. eCollection 2019. Evid Based Complement Alternat Med. 2019. PMID: 31223331 Free PMC article. - An update and systematic review on the treatment of primary dysmenorrhea.
Sharghi M, Mansurkhani SM, Larky DA, Kooti W, Niksefat M, Firoozbakht M, Behzadifar M, Azami M, Servatyari K, Jouybari L. Sharghi M, et al. JBRA Assist Reprod. 2019 Jan 31;23(1):51-57. doi: 10.5935/1518-0557.20180083. JBRA Assist Reprod. 2019. PMID: 30521155 Free PMC article. - Positive Effect of Acupuncture and Cupping in Infertility Treatment.
Wang JX, Yang Y, Song Y, Ma LX. Wang JX, et al. Med Acupunct. 2018 Apr 1;30(2):96-99. doi: 10.1089/acu.2017.1265. Med Acupunct. 2018. PMID: 29682150 Free PMC article. - Immediate Analgesic Effect of Perpendicular Needling or Transverse Needling at SP 6 in Primary Dysmenorrhea: A Pilot Study.
Mohammadi A, Ma LX, Yang Y, Song Y, Wang JX. Mohammadi A, et al. Med Acupunct. 2019 Aug 1;31(4):207-217. doi: 10.1089/acu.2019.1362. Epub 2019 Aug 19. Med Acupunct. 2019. PMID: 31456866 Free PMC article. - Effect of Sanyinjiao (Spleen-6) Acupoint for Pain Management in Primary Dysmenorrhea: An Updated Systematic Review and Meta-Analysis.
Ravi P, Boopalan D, Vijayakumar V, Anandhan A, Vanamoorthy MK, Chidambaram Y, Kasi M, Kuppusamy M. Ravi P, et al. Med Acupunct. 2024 Aug 21;36(4):178-188. doi: 10.1089/acu.2023.0100. eCollection 2024 Aug. Med Acupunct. 2024. PMID: 39309625 Review.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Medical
Research Materials
Miscellaneous