Synthesis of 2’Modified Nucleotides (original) (raw)

Synthesis of 2′–modified nucleotides and their incorporation into hammerhead ribozymes

David Sweedler

Nucleic acids …, 1995

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Synthesis and incorporation of 2′-amino acid conjugated nucleotides into ribozymes

Lech Dudycz

Bioorganic & Medicinal Chemistry Letters, 1995

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Chemical Modification of Hammerhead Ribozymes

David Sweedler

Journal of biological …, 1995

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Nuclease-resistant synthetic ribozymes: developing a new class of therapeutics

Nassim Usman

Journal of Clinical Investigation, 2000

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Chimeric DNA-RNA hammerhead ribozymes have enhancedin vitrocatalytic efficiency and increased stabilityin vivo

Piotr Swiderski

Nucleic Acids Research, 1992

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Highly efficient synthesis of 2′-O-amino nucleosides and their incorporation in hammerhead ribozymes

Alexander Karpeisky

Tetrahedron Letters, 1998

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Ribozyme mimics as catalytic antisense reagents

James Bashkin

Applied Biochemistry and Biotechnology, 1995

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Synthetic Hammerhead Ribozymes as Therapeutic Tools to Control Disease Genes

Lorenzo Citti

Current Gene Therapy, 2005

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Chemically Modified Hammerhead Ribozymes with Improved Catalytic Rates

Nassim Usman

Biochemistry, 1996

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New strategy for the synthesis of chemically modified RNA constructs exemplified by hairpin and hammerhead ribozymes

Tom Brown

2010

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Can hammerhead ribozymes be efficient tools to inactivate gene function

Thierry Grange

Nucleic Acids Research, 1994

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Hammerhead ribozyme engineering

Nassim Usman

Current Opinion in Structural Biology, 1996

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Activity and Stability of Hammerhead Ribozymes Containing 2?-C-Methyluridine: a New RNA Mimic

Mariana Gallo

Chemistry & Biodiversity, 2005

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Synthetic Hammerhead Ribozymes as Tools in Gene Expression

Staale Lyngstadaas

Critical Reviews in Oral Biology & Medicine, 2001

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Design and analysis of hammerhead ribozyme activity against an artificial gene target

Jim Carter

Methods in molecular biology (Clifton, N.J.), 2014

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Ribozymes: recent advances in the development of RNA tools

Alfredo Berzal-herranz

FEMS Microbiology Reviews, 2003

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Modified Hammerhead Ribozymes as Potential Therapeutics

Joachim Engels, Valentin Wittmann

Nucleosides and Nucleotides, 1998

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Recent developments in the hammerhead ribozyme field

Narendra Vaish

Nucleic Acids Research, 1998

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Extensive phosphorothioate substitution yields highly active and nuclease-resistant hairpin ribozymes

John Burke

Nucleic Acids Research, 1992

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Rescue of abasic hammerhead ribozymes by exogenous addition of specific bases

Nassim Usman

Proceedings of the National Academy of Sciences, 1996

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Redesigned and chemically-modified hammerhead ribozymes with improved activity and serum stability

Trevor Lockett

BMC chemical biology, 2004

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The Structure, Function and Application of the Hammerhead Ribozyme

Klara Birikh

European Journal of Biochemistry, 1997

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Thirty-five years of research into ribozymes and nucleic acid catalysis: where do we stand today?

Bettina Appel

F1000Research, 2016

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In vitro selection of a purine nucleotide-specific hammerheadlike ribozyme

Narendra Vaish

Proceedings of the …, 1998

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Building Blocks for Ribozyme Mimics: Conjugates of Terpyridine and Bipyridine with Nucleosides

James Bashkin

The Journal of Organic Chemistry, 1996

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A general approach for the use of oligonucleotide effectors to regulate the catalysis of RNA-cleaving ribozymes and DNAzymes

Dipankar Sen

Nucleic Acids Research, 2002

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Faculty of 1000 evaluation for Capturing hammerhead ribozyme structures in action by modulating general base catalysis

Pascale Legault

F1000 - Post-publication peer review of the biomedical literature, 2008

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Synthesis, deprotection, analysis and purification of RNA and ribosomes

David Sweedler

Nucleic acids …, 1995

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An oligodeoxyribonucleotide that supports catalytic activity in the hammerhead ribozyme domain

Pascal Chartrand

Nucleic Acids Research, 1995

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