α-Conotoxin Vc1.1 Structure–Activity Relationship at the Human α9α10 Nicotinic Acetylcholine Receptor Investigated by Minimal Side Chain Replacement (original ) (raw )Structural mechanisms for α-conotoxin activity at the human α3β4 nicotinic acetylcholine receptor
Lotten Ragnarsson
Scientific reports, 2017
View PDFchevron_right
Key Structural Determinants in the Agonist Binding Loops of Human β2 and β4 Nicotinic Acetylcholine Receptor Subunits Contribute to α3β4 Subtype Selectivity of α-Conotoxins
David J Adams
The Journal of biological chemistry, 2016
View PDFchevron_right
Molecular Determinants Conferring the Stoichiometric-Dependent Activity of α-Conotoxins at the Human α9α10 Nicotinic Acetylcholine Receptor Subtype
David J Adams
Journal of medicinal chemistry, 2018
View PDFchevron_right
Solution structure of α-conotoxin PIA, a novel antagonist of α6 subunit containing nicotinic acetylcholine receptors
Baldomero Olivera
Biochemical and Biophysical Research Communications, 2005
View PDFchevron_right
Solution conformation of a neuronal nicotinic acetylcholine receptor antagonist α-conotoxin OmIA that discriminates α3 vs. α6 nAChR subtypes
Baldomero Olivera
Biochemical and Biophysical Research Communications, 2006
View PDFchevron_right
α-Conotoxins active at α3-containing nicotinic acetylcholine receptors and their molecular determinants for selective inhibition
David J Adams
British journal of pharmacology, 2017
View PDFchevron_right
Orthosteric and/or Allosteric Binding of α-Conotoxins to Nicotinic Acetylcholine Receptors and Their Models
miloud gharrafi
Marine Drugs, 2018
View PDFchevron_right
Molecular determinants of α-conotoxin potency for inhibition of human and rat α6β4 nicotinic acetylcholine receptors
Todd Talley
Journal of Biological Chemistry, 2018
View PDFchevron_right
Positional Scanning Mutagenesis of -Conotoxin PeIA Identifies Critical Residues That Confer Potency and Selectivity for 6/ 3 2 3 and 3 2 Nicotinic Acetylcholine Receptors
Layla Azam
Journal of Biological Chemistry, 2013
View PDFchevron_right
Ribbon α-Conotoxin KTM Exhibits Potent Inhibition of Nicotinic Acetylcholine Receptors
Owen McDougal
Marine Drugs, 2019
View PDFchevron_right
α-Conotoxin PIA Is Selective for α6 Subunit-Containing Nicotinic Acetylcholine Receptors
Baldomero Olivera
The Journal of Neuroscience, 2003
View PDFchevron_right
Mutagenesis of α-Conotoxins for Enhancing Activity and Selectivity for Nicotinic Acetylcholine Receptors
Owen McDougal
Toxins, 2019
View PDFchevron_right
A New α-Conotoxin Which Targets α3β2 Nicotinic Acetylcholine Receptors
Baldomero Olivera
Journal of Biological Chemistry, 1996
View PDFchevron_right
Solution conformation of alpha-conotoxin GIC, a novel potent antagonist of alpha3beta2 nicotinic acetylcholine receptors
Baldomero Olivera
Biochemical Journal, 2004
View PDFchevron_right
αS-Conotoxin RVIIIA: A Structurally Unique Conotoxin That Broadly Targets Nicotinic Acetylcholine Receptors
Baldomero Olivera
Biochemistry
View PDFchevron_right
alpha.-Conotoxin EI, A New Nicotinic Acetylcholine Receptor Antagonist with Novel Selectivity
Baldomero Olivera
Biochemistry, 1995
View PDFchevron_right
Novel ?-conotoxins from Conus spurius and the ?-conotoxin EI share high-affinity potentiation and low-affinity inhibition of nicotinic acetylcholine receptors
Francesco Peri
Febs Journal, 2007
View PDFchevron_right
Alanine Scan of α-Conotoxin RegIIA Reveals a Selective α3β4 Nicotinic Acetylcholine Receptor Antagonist
David J Adams
Journal of Biological Chemistry, 2014
View PDFchevron_right
Differential Targeting of Nicotinic Acetylcholine Receptors by Novel αA-Conotoxins
Baldomero Olivera
Journal of Biological Chemistry, 1997
View PDFchevron_right
Alpha-conotoxins as pharmacological probes of nicotinic acetylcholine receptors
Michael McIntosh
Acta Pharmacologica Sinica, 2009
View PDFchevron_right
Amino Acid Residues That Confer High Selectivity of the 6 Nicotinic Acetylcholine Receptor Subunit to -Conotoxin MII[S4A,E11A,L15A]
Layla Azam
Journal of Biological Chemistry, 2008
View PDFchevron_right
Conotoxin αD-GeXXA utilizes a novel strategy to antagonize nicotinic acetylcholine receptors
David J Adams
Scientific reports, 2015
View PDFchevron_right
α4/7-conotoxin Lp1.1 is a novel antagonist of neuronal nicotinic acetylcholine receptors
Tanya Sanders
Peptides, 2008
View PDFchevron_right
Single amino acid substitutions in α-conotoxin PnIA shift selectivity for subtypes of the mammalian neuronal nicotinic acetylcholine receptor
David J Adams
1999
View PDFchevron_right
Solution Conformation of αA-conotoxin EIVA, a Potent Neuromuscular Nicotinic Acetylcholine Receptor Antagonist from Conus ermineus
Baldomero Olivera
Journal of Biological Chemistry, 2003
View PDFchevron_right
alpha.-Conotoxins, small peptide probes of nicotinic acetylcholine receptors
Lourdes J Cruz
Biochemistry, 1991
View PDFchevron_right
αS-conotoxin GVIIIB potently and selectively blocks α9α10 nicotinic acetylcholine receptors
Baldomero Olivera
Biochemical pharmacology, 2015
View PDFchevron_right
Crystal structure of nicotinic acetylcholine receptor homolog AChBP in complex with an α-conotoxin PnIA variant
Maxim Zhmak
Nature Structural & Molecular Biology, 2005
View PDFchevron_right
α-Conotoxins EpI and AuIB switch subtype selectivity and activity in native versus recombinant nicotinic acetylcholine receptors
Alfred Maelicke
FEBS Letters, 2003
View PDFchevron_right
α-Conotoxin OmIA Is a Potent Ligand for the Acetylcholine-binding Protein as Well as α3β2 and α7 Nicotinic Acetylcholine Receptors
Baldomero Olivera
Journal of Biological Chemistry, 2006
View PDFchevron_right
Atypical -Conotoxin LtIA from Conus litteratus Targets a Novel Microsite of the 3 2 Nicotinic Receptor
Cheryl Dowell
Journal of Biological Chemistry, 2010
View PDFchevron_right
α-Conotoxins PnIA and [A10L]PnIA Stabilize Different States of the α7-L247T Nicotinic Acetylcholine Receptor
David J Adams
Journal of Biological Chemistry, 2003
View PDFchevron_right