Ribbon α-Conotoxin KTM Exhibits Potent Inhibition of Nicotinic Acetylcholine Receptors (original) (raw)
NMR solution conformation of an antitoxic analogue of alpha-conotoxin GI: identification of a common nicotinic acetylcholine receptor alpha 1-subunit binding surface for small ligands and alpha-conotoxins
K. Hun Mok
Biochemistry
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NMR Solution Conformation of an Antitoxic Analogue of α-Conotoxin GI: Identification of a Common Nicotinic Acetylcholine Receptor α 1 -Subunit Binding Surface for Small Ligands and α-Conotoxins † , ‡
K. Hun Mok
Biochemistry, 1999
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NMR structure determination of α-conotoxin BuIA, a novel neuronal nicotinic acetylcholine receptor antagonist with an unusual 4/4 disulfide scaffold
Baldomero Olivera
Biochemical and Biophysical Research Communications, 2006
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Solution structure of α-conotoxin PIA, a novel antagonist of α6 subunit containing nicotinic acetylcholine receptors
Baldomero Olivera
Biochemical and Biophysical Research Communications, 2005
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Solution conformation of a neuronal nicotinic acetylcholine receptor antagonist α-conotoxin OmIA that discriminates α3 vs. α6 nAChR subtypes
Baldomero Olivera
Biochemical and Biophysical Research Communications, 2006
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Solution conformation of alpha-conotoxin GIC, a novel potent antagonist of alpha3beta2 nicotinic acetylcholine receptors
Baldomero Olivera
Biochemical Journal, 2004
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Three-Dimensional Solution Structure of α-Conotoxin MII, an α3β2 Neuronal Nicotinic Acetylcholine Receptor-Targeted Ligand
Baldomero Olivera
Biochemistry, 1997
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Nuclear Magnetic Resonance Solution Conformation of α-Conotoxin AuIB, an α3β4 Subtype-selective Neuronal Nicotinic Acetylcholine Receptor Antagonist
Baldomero Olivera
Journal of Biological Chemistry, 2000
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Structural mechanisms for α-conotoxin activity at the human α3β4 nicotinic acetylcholine receptor
Lotten Ragnarsson
Scientific reports, 2017
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Alanine Scan of α-Conotoxin RegIIA Reveals a Selective α3β4 Nicotinic Acetylcholine Receptor Antagonist
David J Adams
Journal of Biological Chemistry, 2014
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Molecular determinants of α-conotoxin potency for inhibition of human and rat α6β4 nicotinic acetylcholine receptors
Todd Talley
Journal of Biological Chemistry, 2018
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A Novel Lid-Covering Peptide Inhibitor of Nicotinic Acetylcholine Receptors Derived from αD-Conotoxin GeXXA
David J Adams
Marine drugs, 2017
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alpha.-Conotoxin EI, A New Nicotinic Acetylcholine Receptor Antagonist with Novel Selectivity
Baldomero Olivera
Biochemistry, 1995
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Crystal structure of nicotinic acetylcholine receptor homolog AChBP in complex with an α-conotoxin PnIA variant
Maxim Zhmak
Nature Structural & Molecular Biology, 2005
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NMR structure of alpha-bungarotoxin free and bound to a mimotope of the nicotinic acetylcholine receptor
Ottavia Spiga
Biochemistry, 2002
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A New α-Conotoxin Which Targets α3β2 Nicotinic Acetylcholine Receptors
Baldomero Olivera
Journal of Biological Chemistry, 1996
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Conotoxin αD-GeXXA utilizes a novel strategy to antagonize nicotinic acetylcholine receptors
David J Adams
Scientific reports, 2015
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Differential Targeting of Nicotinic Acetylcholine Receptors by Novel αA-Conotoxins
Baldomero Olivera
Journal of Biological Chemistry, 1997
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Rational Design of α-Conotoxin Analogues Targeting a7 Nicotinic Acetylcholine Receptors : IMPROVED ANTAGONISTIC ACTIVITY BY INCORPORATION OF PROLINE DERIVATIVES
Kasper Harpsøe
The Journal of Biological Chemistry, 2009
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Solution Conformation of αA-conotoxin EIVA, a Potent Neuromuscular Nicotinic Acetylcholine Receptor Antagonist from Conus ermineus
Baldomero Olivera
Journal of Biological Chemistry, 2003
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NMR Structure of α-Bungarotoxin Free and Bound to a Mimotope of the Nicotinic Acetylcholine Receptor †
Ottavia Spiga
Biochemistry, 2002
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Rational Design of -Conotoxin Analogues Targeting 7 Nicotinic Acetylcholine Receptors: IMPROVED ANTAGONISTIC ACTIVITY BY INCORPORATION OF PROLINE DERIVATIVES
Christian Skonberg
Journal of Biological Chemistry, 2009
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α-Conotoxins active at α3-containing nicotinic acetylcholine receptors and their molecular determinants for selective inhibition
David J Adams
British journal of pharmacology, 2017
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Mutagenesis of α-Conotoxins for Enhancing Activity and Selectivity for Nicotinic Acetylcholine Receptors
Owen McDougal
Toxins, 2019
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Determinants of Potency on α-Conotoxin MII, a Peptide Antagonist of Neuronal Nicotinic Receptors
Aldrin Gomes
Biochemistry, 2004
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Discovery of a Potent and Selective α3β4 Nicotinic Acetylcholine Receptor Antagonist from an α-Conotoxin Synthetic Combinatorial Library
Yi-Pin Chang
Journal of Medicinal Chemistry, 2014
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NMR-based binding screen and structural analysis of the complex formed between α-cobratoxin and an 18-mer cognate peptide derived from the α1 subunit of the nicotinic acetylcholine receptor from torpedo californica
Allison Zumberge
Journal of Biological Chemistry, 2002
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Analogs of -Conotoxin MII Are Selective for 6-Containing Nicotinic Acetylcholine Receptors
Layla Azam
Molecular Pharmacology, 2004
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Discovery, Synthesis, and Structure Activity of a Highly Selective α7 Nicotinic Acetylcholine Receptor Antagonist
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Characterization and Three-Dimensional Structure Determination of ψ-Conotoxin Piiif, a Novel Noncompetitive Antagonist of Nicotinic Acetylcholine Receptors
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Biochemistry, 2003
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α-Conotoxin Vc1.1 Structure–Activity Relationship at the Human α9α10 Nicotinic Acetylcholine Receptor Investigated by Minimal Side Chain Replacement
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Stoichiometry dependent inhibition of rat α3β4 nicotinic acetylcholine receptor by the ribbon isomer of α-conotoxin AuIB
David J Adams
Biochemical pharmacology, 2018
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alpha.-Conotoxins, small peptide probes of nicotinic acetylcholine receptors
Lourdes J Cruz
Biochemistry, 1991
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Towards structure determination of neurotoxin II bound to nicotinic acetylcholine receptor: a solid-state NMR approach
Alexander Arseniev
FEBS Letters, 2004
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