Total chemical synthesis of a functional interacting protein pair: The protooncogene H-Ras and the Ras-binding domain of its effector c-Raf1 (original ) (raw )Design, total chemical synthesis, and binding properties of a [Leu-91-N1-methyl-7-azaTrp]Ras-binding domain of c-Raf-1
Jens Sydor , Martin Engelhard
Proceedings of the National Academy of Sciences, 1999
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A sensitive fluorescence monitor for the detection of activated Ras: total chemical synthesis of site-specifically labeled Ras binding domain of c-Raf1 immobilized on a surface
Christie Hunter
Chemistry & Biology, 2001
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Synthesis of Functional Ras Lipoproteins and Fluorescent Derivatives
Benjamin Bader
Journal of the American Chemical Society, 2001
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Synthesis of degenerated libraries of the ras-binding domain of raf and rapid selection of fast-folding and stable clones with the dihydrofolate reductase protein fragment complementation assay
François-xavier Campbell-valois
Methods in molecular biology (Clifton, N.J.), 2007
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Expanding the chemical toolbox for the synthesis of large and uniquely modified proteins
Somasekhar Bondalapati
Nature Chemistry, 2016
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Chemical synthesis of proteins
Gregg Fields
Trends in Biotechnology, 2000
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Modification and Activation of Ras Proteins by Electrophilic Prostanoids with Different Structure are Site-Selective
Andrea Perez
Biochemistry, 2007
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Synthesis of the Rheb and K-Ras4B GTPases
Debapratim Das
Angewandte Chemie, 2010
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Introduction of unnatural amino acids into proteins using expressed protein ligationStandard IUPAC single- and triple-letter codes for amino acids are used throughout the article
Julio Camarero
Biopolymers, 1999
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Identification of ras/raf binding site and design of interfering peptide with potential clinical application
sylvain choquet
Integrative molecular medicine, 2016
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DNA-instructed acyl transfer reactions for the synthesis of bioactive peptides
Tom Grossmann
Bioorganic & Medicinal Chemistry Letters, 2011
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Protein and nucleic acid engineering. Recent French contributions. Part I
Alan Fersht
Biochimie, 1990
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Mutational analysis of a ras catalytic domain
Berthe Willumsen
Molecular and Cellular Biology, 1986
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Synthesis, characterization and solution properties of ras sequences modified by arylamine carcinogens at the first base of codon 61
Victor Day
Chemical Research in Toxicology, 1990
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Binding properties and biological characterization of new sugar-derived Ras ligands
Vadim Gaponenko , Alessandro Palmioli , Francesco Peri
MedChemComm, 2011
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Synthesis of novel proteins
Francesc Rabanal
Current Opinion in Chemical Biology, 1997
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Photoaffinity labeling of Ras converting enzyme 1 (Rcelp) using a benzophenone-containing peptide substrate
Kelly Kyro , Surya Manandhar
Bioorganic Medicinal Chemistry, 2010
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Through the looking glass - a new world of proteins enabled by chemical synthesis
Kalyaneswar Mandal
Journal of Peptide Science, 2012
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The C-Terminus of H-Ras as a Target for the Covalent Binding of Reactive Compounds Modulating Ras-Dependent Pathways
David Andreu
PLoS ONE, 2011
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Chemical Synthesis of Proteins Containing 300 Amino Acids
yulei li
Chemical Research in Chinese Universities, 2020
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Structure Determination and Dynamics of Peptides Overlapping the Catalytic Hairpin of the Ras-Specific GEF Cdc25 Mm †
Teresa Recca
Biochemistry, 2003
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Dynamically encoded reactivity of Ras enzymes: opening new frontiers for drug discovery
Gyula Pálfy
Cancer and Metastasis Reviews
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Semisynthesis of Dimeric Proteins by Expressed Protein Ligation
Luca D'andrea
Organic Letters, 2008
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Characterization of a 78-residue fragment of c-Raf-1 that comprises a minimal binding domain for the interaction with Ras-GTP
Kathleen Prinzo
Journal of Biological Chemistry, 1994
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Elucidating Structural Details of Ras-Effector Interactions
Saliha Ece Acuner Zorluuysal
International Journal of Advances in Engineering and Pure Sciences, 2019
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Targeting Ras with Macromolecules
Dehua Pei
Cold Spring Harbor Perspectives in Medicine, 2017
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Chemical synthesis of proteins: a tool for protein labeling
Lucia Rosa
2010
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Analysis of the Transforming Potential of the Human H-ras Gene by Random Mutagenesis
Mark Furth
Proceedings of The National Academy of Sciences, 1984
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Improved Binding of Raf to Ras·GDP Is Correlated with Biological Activity
Hans Kalbitzer
Journal of Biological Chemistry, 2009
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A High-throughput Approach to NRPS Domain Substitution for Generation of Novel Peptides
Sarah Messenger
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Synthesis of GTP-Derived Ras Ligands
Herbert Waldmann
ChemBioChem, 2004
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Editorial [Hot Topic: Polypeptide Chemical Ligation Tools in Protein Engineering (Guest Editor: Julio A. Camarero)]
Julio Camarero
Protein & Peptide Letters, 2005
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Isoprenoid addition to Ras protein is the critical modification for its membrane association and transforming activity
Channing Der
Proceedings of the National Academy of Sciences, 1992
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Kinetics of interaction of nucleotides with nucleotide-free H-ras p21
Juergen Feuerstein
Biochemistry, 1990
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