Characterization of human immunodeficiency virus type 1 mutantswith decreased sensitivity to proteinase inhibitor Ro 31-8959 (original) (raw)
The virus-associated human immunodeficiency virus type 1 Gag-Pol carrying an active protease domain in the matrix region is severely defective both in autoprocessing and in trans processing of gag particles
Fu-der Wang
Virology, 2004
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Extensive Regions ofpolAre Required for Efficient Human Immunodeficiency Virus Polyprotein Processing and Particle Maturation
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Replacement of the P1 amino acid of human immunodeficiency virus type 1 Gag processing sites can inhibit or enhance the rate of cleavage by the viral protease
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Initial Cleavage of the Human Immunodeficiency Virus Type 1 GagPol Precursor by Its Activated Protease Occurs by an Intramolecular Mechanism
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HIV-1 Gag Processing Intermediates Trans-dominantly Interfere with HIV-1 Infectivity
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Thomas Meek
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Richard Collins III
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Elena Chertova
Journal of Virology, 2003
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Trans-dominant inhibitory human immunodeficiency virus type 1 protease monomers prevent protease activation and virion maturation
Charles Craik
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Active human immunodeficiency virus protease is required for viral infectivity
Emilio Emini
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Journal of Virology, 1997
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Characterization of Deletion Mutations in the Capsid Region of Human Immunodeficiency Virus Type 1 That Affect Particle Formation and Gag-Pol Precursor Incorporation
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Human immunodeficiency virus type 1 Pr55gag and Pr160gag-pol expressed from a simian virus 40 late replacement vector are efficiently processed and assembled into viruslike particles
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Removal of human immunodeficiency virus type 1 (HIV-1) protease inhibitors from preparations of immature HIV-1 virions does not result in an increase in infectivity or the appearance of mature morphology
TOMINAGA FUKAZAWA
Antimicrobial Agents and Chemotherapy, 1997
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Requirement of the Pr55gag precursor for incorporation of the Vpr product into human immunodeficiency virus type 1 viral particles
Xiaojian Yao
Journal of virology, 1994
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Contribution of the Gag-Pol transframe domain p6* and its coding sequence to morphogenesis and replication of human immunodeficiency virus type 1
Ralf Wagner
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HIV-1 Protease Dimer Interface Mutations that Compensate for Viral Reverse Transcriptase Instability in Infectious Virions
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Human immunodeficiency virus type 1 Vif binds the viral protease by interaction with its N-terminal region
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The Journal of general virology, 2002
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Proteolytic activity in vivo and encapsidation of recombinant human immunodeficiency virus type 1 proteinase expressed in baculovirus-infected cells
Bernard Gay
The Journal of general virology, 1997
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Incorporation of Vpr into Human Immunodeficiency Virus Type 1 Requires a Direct Interaction with the p6 Domain of the p55 Gag Precursor
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The Role of Gag in Human Immunodeficiency Virus Type 1 Virion Morphogenesis and Early Steps of the Viral Life Cycle
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Linker insertion mutations in the human immunodeficiency virus type 1 gag gene: effects on virion particle assembly, release, and infectivity
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Mutations in HIV-1 gag and pol Compensate for the Loss of Viral Fitness Caused by a Highly Mutated Protease
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Requirements for incorporation of Pr160gag-pol from human immunodeficiency virus type 1 into virus-like particles
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