Scar1 and the related Wiskott–Aldrich syndrome protein, WASP, regulate the actin cytoskeleton through the Arp2/3 complex (original) (raw)

Scar, a WASp-related protein, activates nucleation of actin filaments by the Arp2/3 complex

Laura Machesky

Proceedings of the National Academy of Sciences, 1999

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How WASP-family proteins and the Arp2/3 complex convert intracellular signals into cytoskeletal structures

Dyche Mullins

Current Opinion in Cell Biology, 2000

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Different WASP family proteins stimulate different Arp2/3 complex-dependent actin-nucleating activities

Dyche Mullins

Current Biology, 2001

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SCAR is a primary regulator of Arp2/3-dependent morphological events in Drosophila

Eric Wieschaus

The Journal of Cell Biology, 2002

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The WASP–Arp2/3 pathway: genetic insights

Laura Machesky, Maria Vartiainen

Current Opinion in Cell Biology, 2004

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Arp2/3 complex is bound and activated by two WASP proteins

David King

Proceedings of the National Academy of Sciences, 2011

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The p40/ARPC1 Subunit of Arp2/3 Complex Performs Multiple Essential Roles in WASp-regulated Actin Nucleation

Bruce Goode

Journal of Biological Chemistry, 2010

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Signalling to actin: the Cdc42-N-WASP-Arp2/3 connection

Dominique Pantaloni

Chemistry & Biology, 1999

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Activation of the Arp2/3 Complex by the Actin Filament Binding Protein Abp1p

Bruce Goode

The Journal of Cell Biology, 2001

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WASP family proteins, more than Arp2/3 activators

Ellen Allwood

Biochemical Society transactions, 2016

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Structure of Arp2/3 Complex in Its Activated State and in Actin Filament Branch Junctions

Dorit Hanein

Science, 2001

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The F-actin side binding activity of the Arp2/3 complex is essential for actin nucleation and lamellipod extension

Noureddine Zebda

Current Biology, 2001

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Phosphorylation of the Arp2/3 complex is necessary to nucleate actin filaments

Dyche Mullins

Journal of Cell Biology, 2008

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WIP regulates N-WASP-mediated actin polymerization and filopodium formation

Inés Antón

2001

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Arp2/3 complex-mediated actin polymerisation occurs on specific pre-existing networks in cells and requires spatial restriction to sustain functional lamellipod extension

Peter Munro

Cell motility and the cytoskeleton, 2006

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WAVE, a novel WASP-family protein involved in actin reorganization induced by Rac

Shiro Suetsugu

The EMBO Journal, 1998

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The Interaction between N-WASP and the Arp2/3 Complex Links Cdc42-Dependent Signals to Actin Assembly

MARCO LOPEZ

Cell, 1999

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Spatial and temporal regulation of actin polymerization for cytoskeleton formation through Arp2/3 complex and WASP/WAVE proteins

Shiro Suetsugu

Cell Motility and The Cytoskeleton, 2002

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WASP and SCAR have distinct roles in activating the Arp2/3 complex during myoblast fusion

Renate Renkawitz-pohl

Journal of Cell Science, 2008

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A conserved amphipathic helix in WASP/Scar proteins is essential for activation of Arp2/3 complex

Eduardo martinez torres

Nature Structural Biology, 2003

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Expression of WASP and Scar1/WAVE1 actin-associated proteins is differentially modulated during differentiation of HL-60 cells

Sophie Launay

Cell motility and the cytoskeleton, 2003

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Two tandem verprolin homology domains are necessary for a strong activation of Arp2/3 complex-induced actin polymerization and induction of microspike formation by N-WASP

Shiro Suetsugu

Proceedings of The National Academy of Sciences, 2000

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Dock mediates Scar- and WASp-dependent actin polymerization through interaction with cell adhesion molecules in founder cells and fusion-competent myoblasts

Susanne-filiz Oenel

Journal of Cell Science, 2012

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The Actin Cytoskeleton in Yeast and Animal Cells

Scholar Science Journals

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Requirement of the Basic Region of N-WASP/WAVE2 for Actin-Based Motility

Shiro Suetsugu

Biochemical and Biophysical Research Communications, 2001

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Abi, Sra1, and Kette control the stability and localization of SCAR/WAVE to regulate the formation of actin-based protrusions

Patricia Kunda

Current biology, 2003

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Author response: Three-color single molecule imaging shows WASP detachment from Arp2/3 complex triggers actin filament branch formation

Bruce Goode

2013

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Arp2/3 Complex Inhibition Radically Alters Lamellipodial Actin Architecture, Suspended Cell Shape, and the Cell Spreading Process

Charles Shuster

Molecular biology of the cell, 2015

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How distinct Arp2/3 complex variants regulate actin filament assembly

Theresia Stradal

Nature Cell Biology, 2015

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IQGAP1 Stimulates Actin Assembly through the N-Wasp-Arp2/3 Pathway

Christophe Le Clainche

Journal of Biological Chemistry, 2007

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