The E3 Ubiquitin Ligases HRD1 and SCFFbs2 Recognize the Protein Moiety and Sugar Chains, Respectively, of an ER‐Associated Degradation Substrate (original) (raw)

A Shared Endoplasmic Reticulum-associated Degradation Pathway Involving the EDEM1 Protein for Glycosylated and Nonglycosylated Proteins

Linda Hendershot

Journal of Biological Chemistry, 2013

View PDFchevron_right

Membrane Topology and Function of Der3/Hrd1p as a Ubiquitin-Protein Ligase (E3) Involved in Endoplasmic Reticulum Degradation

Dieter H Wolf

Journal of Biological Chemistry, 2001

View PDFchevron_right

Previously unknown role for the ubiquitin ligase Ubr1 in endoplasmic reticulum-associated protein degradation

Dieter H Wolf

Proceedings of the National Academy of Sciences, 2013

View PDFchevron_right

Human HRD1 Is an E3 Ubiquitin Ligase Involved in Degradation of Proteins from the Endoplasmic Reticulum

Ram Doolman

Journal of Biological Chemistry, 2003

View PDFchevron_right

2011 An unusual transmembrane helix in the endoplasmic reticulum ubiquitin ligase Doa10 modulates degradation of its cognate E2 enzyme. The Journal of biological chemistry 286

Mark Hochstrasser

2016

View PDFchevron_right

Structural basis of ER-associated protein degradation mediated by the Hrd1 ubiquitin ligase complex

Linda Hendershot

Faculty reviews, 2022

View PDFchevron_right

Degradation of a Cytosolic Protein Requires Endoplasmic Reticulum-associated Degradation Machinery

Beverley M (Dancy) Rabbitts

Journal of Biological Chemistry, 2008

View PDFchevron_right

A subset of membrane-associated proteins is ubiquitinated in response to mutations in the endoplasmic reticulum degradation machinery

Pamela Silver

Proceedings of the National Academy of Sciences, 2003

View PDFchevron_right

A role for mammalian Ubc6 homologues in ER-associated protein degradation

Helen Yu

Journal of Cell Science, 2002

View PDFchevron_right

Genome-wide identification and gene expression profiling of ubiquitin ligases for endoplasmic reticulum protein degradation

Sudip Kumar Dutta

Scientific reports, 2016

View PDFchevron_right

Selective Targeting of Proteins within Secretory Pathway for Endoplasmic Reticulum-associated Degradation

Marco Bestagno

Journal of Biological Chemistry, 2012

View PDFchevron_right

Disposing of misfolded ER proteins: A troubled substrate's way out of the ER

Linda Hendershot

Molecular and Cellular Endocrinology, 2019

View PDFchevron_right

A complex of Yos9p and the HRD ligase integrates endoplasmic reticulum quality control into the degradation machinery

Ernst Jarosch, Thomas Sommer

Nature Cell Biology, 2006

View PDFchevron_right

A novel mammalian endoplasmic reticulum ubiquitin ligase homologous to the yeast Hrd1

Hedva Gonen

Biochemical and Biophysical Research Communications, 2003

View PDFchevron_right

Htm1 protein generates the N-glycan signal for glycoprotein degradation in the endoplasmic reticulum

Thomas Sommer

The Journal of Cell Biology, 2009

View PDFchevron_right

Intrinsic Conformational Determinants Signal Protein Misfolding to the Hrd1/Htm1 Endoplasmic Reticulum-associated Degradation System

Ayaz Sayeed

Molecular Biology of the Cell, 2009

View PDFchevron_right

Conserved cytoplasmic domains promote Hrd1 ubiquitin ligase complex formation for ER-associated degradation (ERAD)

Markus Queisser

Journal of Cell Science, 2017

View PDFchevron_right

Distinct activation of an E2 ubiquitin-conjugating enzyme by its cognate E3 ligases

Yuval Reiss

Proceedings of the National Academy of Sciences of the United States of America, 2015

View PDFchevron_right

Sec61p is part of the endoplasmic reticulum-associated degradation machinery

Dieter H Wolf

The EMBO Journal, 2009

View PDFchevron_right

Ubx4 Modulates Cdc48 Activity and Influences Degradation of Misfolded Proteins of the Endoplasmic Reticulum

Dieter H Wolf

Journal of Biological Chemistry, 2009

View PDFchevron_right

The AAA ATPase p97 links peptide N-glycanase to the endoplasmic reticulum-associated E3 ligase autocrine motility factor receptor

William Lennarz

Proceedings of the National Academy of Sciences, 2006

View PDFchevron_right

The TRC8 E3 ligase ubiquitinates MHC class I molecules before dislocation from the ER

Robert Gemmill

Journal of Experimental Medicine, 2009

View PDFchevron_right

Yos9, a control protein for misfolded glycosylated and non-glycosylated proteins in ERAD

Dieter H Wolf

FEBS Letters, 2011

View PDFchevron_right

Ubiquitin-dependent protein degradation at the endoplasmic reticulum and nuclear envelope

Adrian Mehrtash

Seminars in Cell & Developmental Biology, 2018

View PDFchevron_right

Der3p/Hrd1p is required for endoplasmic reticulum-associated degradation of misfolded lumenal and integral membrane proteins

Dieter H Wolf, Richard Plemper

Molecular biology of the cell, 1998

View PDFchevron_right

The VCP/p97 and YOD1 Proteins Have Different Substrate-dependent Activities in Endoplasmic Reticulum-associated Degradation (ERAD)

Oscar Burrone

Journal of Biological Chemistry, 2015

View PDFchevron_right

A genome-wide screen identifies Yos9p as essential for ER-associated degradation of glycoproteins

Dieter H Wolf

FEBS Letters, 2004

View PDFchevron_right

Editorial: E3 Ubiquitin Ligases: From Structure to Physiology

Victor Bolanos-garcia

Frontiers in Physiology, 2020

View PDFchevron_right

Endoplasmic reticulum-associated protein degradation

Lorenzo Frigerio

Seminars in Cell and …, 2000

View PDFchevron_right

Ubx2 links the Cdc48 complex to ER-associated protein degradation

Ernst Jarosch, Thomas Sommer

Nature Cell Biology, 2005

View PDFchevron_right

Endoplasmic reticulum (ER)-associated degradation of T cell receptor subunits

Swati Tiwari

Journal of Biological Chemistry, 2001

View PDFchevron_right

Endoplasmic reticulum quality control of asialoglycoprotein receptor H2a involves a determinant for retention and not retrieval

Michal Ayalon

Proceedings of the National Academy of Sciences, 1997

View PDFchevron_right

Endoplasmic reticulum-associated protein degradation—one model fits all?

Bassam Ali

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2004

View PDFchevron_right

Ubiquitin-specific protease 25 functions in Endoplasmic Reticulum-associated degradation

Gemma Marfany

PloS one, 2012

View PDFchevron_right

Multiple Endoplasmic Reticulum-associated Pathways Degrade Mutant Yeast Carboxypeptidase Y in Mammalian Cells

Ari Helenius

Journal of Biological Chemistry, 2003

View PDFchevron_right