Previously unknown role for the ubiquitin ligase Ubr1 in endoplasmic reticulum-associated protein degradation (original) (raw)

Membrane Topology and Function of Der3/Hrd1p as a Ubiquitin-Protein Ligase (E3) Involved in Endoplasmic Reticulum Degradation

Dieter H Wolf

Journal of Biological Chemistry, 2001

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2011 An unusual transmembrane helix in the endoplasmic reticulum ubiquitin ligase Doa10 modulates degradation of its cognate E2 enzyme. The Journal of biological chemistry 286

Mark Hochstrasser

2016

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A subset of membrane-associated proteins is ubiquitinated in response to mutations in the endoplasmic reticulum degradation machinery

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Proceedings of the National Academy of Sciences, 2003

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The E3 Ubiquitin Ligases HRD1 and SCFFbs2 Recognize the Protein Moiety and Sugar Chains, Respectively, of an ER‐Associated Degradation Substrate

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Israel Journal of Chemistry, 2006

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Degradation of a Cytosolic Protein Requires Endoplasmic Reticulum-associated Degradation Machinery

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A complex of Yos9p and the HRD ligase integrates endoplasmic reticulum quality control into the degradation machinery

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Endoplasmic reticulum-associated protein degradation

Thomas Sommer

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The VCP/p97 and YOD1 Proteins Have Different Substrate-dependent Activities in Endoplasmic Reticulum-associated Degradation (ERAD)

Oscar Burrone

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Structural basis of ER-associated protein degradation mediated by the Hrd1 ubiquitin ligase complex

Linda Hendershot

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Human HRD1 Is an E3 Ubiquitin Ligase Involved in Degradation of Proteins from the Endoplasmic Reticulum

Ram Doolman

Journal of Biological Chemistry, 2003

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Genome-wide identification and gene expression profiling of ubiquitin ligases for endoplasmic reticulum protein degradation

Sudip Kumar Dutta

Scientific reports, 2016

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VCP/p97 and YOD1 have different substrate-dependent activities in endoplasmic reticulum-associated degradation (ERAD)

Gianluca Petris

Journal of Biological Chemistry, 2015

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A Proteasomal ATPase Contributes to Dislocation of Endoplasmic Reticulum-associated Degradation (ERAD) Substrates

Shoshana Bar-nun

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ER-associated degradation (ERAD): Novel components and cellular regulation

Sigurd Braun

2005

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A genomic screen identifies Dsk2p and Rad23p as essential components of ER-associated degradation

Dieter H Wolf

EMBO reports, 2004

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Ubiquitin-specific protease 25 functions in Endoplasmic Reticulum-associated degradation

Gemma Marfany

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Gp78 Cooperates with RMA1 in Endoplasmic Reticulum-associated Degradation of CFTRΔF508

Kazuhiro Iwai

Molecular Biology of the Cell, 2008

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A role for mammalian Ubc6 homologues in ER-associated protein degradation

Helen Yu

Journal of Cell Science, 2002

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Endoplasmic Reticulum Degradation of a Mutated ATP-binding Cassette Transporter Pdr5 Proceeds in a Concerted Action of Sec61 and the Proteasome

Karl Kuchler

Journal of Biological Chemistry, 1998

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Conserved cytoplasmic domains promote Hrd1 ubiquitin ligase complex formation for ER-associated degradation (ERAD)

Markus Queisser

Journal of Cell Science, 2017

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ER degradation' of a mutant yeast plasma membrane protein by the ubiquitin-proteasome pathway

Jm Galan

FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 1998

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Sec61p is part of the endoplasmic reticulum-associated degradation machinery

Dieter H Wolf

The EMBO Journal, 2009

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Multiple Endoplasmic Reticulum-associated Pathways Degrade Mutant Yeast Carboxypeptidase Y in Mammalian Cells

Ari Helenius

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Der3p/Hrd1p is required for endoplasmic reticulum-associated degradation of misfolded lumenal and integral membrane proteins

Dieter H Wolf, Richard Plemper

Molecular biology of the cell, 1998

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Disposing of misfolded ER proteins: A troubled substrate's way out of the ER

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Molecular and Cellular Endocrinology, 2019

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The ER-resident ubiquitin-specific protease 19 participates in the UPR and rescues ERAD substrates

Mikael Altun

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Ubx4 Modulates Cdc48 Activity and Influences Degradation of Misfolded Proteins of the Endoplasmic Reticulum

Dieter H Wolf

Journal of Biological Chemistry, 2009

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Identification of an Htm1 (EDEM)-dependent, Mns1-independent Endoplasmic Reticulum-associated Degradation (ERAD) Pathway in Saccharomyces cerevisiae: APPLICATION OF A NOVEL ASSAY FOR GLYCOPROTEIN ERAD

Hiroto Hirayama

Journal of Biological Chemistry, 2010

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Ubiquitin-recognition protein Ufd1 couples the endoplasmic reticulum (ER) stress response to cell cycle control

Ze'ev Ronai

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ER-associated degradation: Protein quality control and beyond

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Journal of Cell Biology, 2014

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A novel mammalian endoplasmic reticulum ubiquitin ligase homologous to the yeast Hrd1

Hedva Gonen

Biochemical and Biophysical Research Communications, 2003

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The Hrd1p ligase complex forms a linchpin between ER-lumenal substrate selection and Cdc48p recruitment

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Distinct activation of an E2 ubiquitin-conjugating enzyme by its cognate E3 ligases

Yuval Reiss

Proceedings of the National Academy of Sciences of the United States of America, 2015

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Endoplasmic reticulum degradation: reverse protein flow of no return

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AAA-ATPase p97/Cdc48p, a cytosolic chaperone required for endoplasmic reticulum-associated protein degradation

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2002

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