Biochemical Properties of 5‐SULFUR‐SUBSTITUTED Pyrimidine Nucleosides and Nucleotides* (original) (raw)
Spectrophotometric and chemical studies of 5-mercaptouracil, 5-mercaptodeoxyuridine, and their S-substituted derivatives
Thomas Kalman
Journal of pharmaceutical sciences, 1966
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The reactions of mercurated pyrimidine nucleotides with thiols and with hydrogen sulfide
Christine Van Broeckhoven
Nucleic Acids Research, 1978
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5-Mercaptodeoxyuridine—Its enzymatic synthesis and mode of action in microbiological systems
Thomas Kalman
Biochemical Pharmacology, 1969
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5-Substituted pyrimidine nucleosides and nucleotides
Tony K Bradshaw
Chemical Society Reviews, 1977
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Formation of 6-thioxanthosine 5′-phosphate from 6-mercaptopurine and from 6-thioxanthine in Ehrlich ascites-tumour cells
jan stephenson
Biochimica Et Biophysica Acta (bba) - Nucleic Acids and Protein Synthesis - BIOCHIM BIOPHYS ACTA NUCLEIC ACIDS PROTEIN SYNTH, 1965
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Interaction of 5-fluoro-4-thio-2′-deoxyuridine 5′-phosphate with mammalian tumour thymidylate synthase: Role of the pyrimidine N(3)-H dissociation
Joanna Ciesla
Biochemical and Biophysical Research Communications, 1987
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Synthesis and biological activity of 5-fluoro-4'-thiouridine and some related nucleosides
Sp Dutta
Journal of Medicinal Chemistry, 1975
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Inhibition of poly(ADP-ribose)polymerase activity by nucleoside analogs of thymidine
Joanna Rzeszowska-wolny
Biochemical Pharmacology, 1992
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Methylation of 4-thio-2′-deoxyuridylate by thymidylate synthetase
Thomas Kalman
Biochemical and Biophysical Research Communications, 1973
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Studies on the interaction with thymidylate synthase of analogues of 2′-deoxyuridine-5′-phosphate and 5-fluoro-2′-deoxyuridine-5′-phosphate with modified phosphate groups
Wojciech Rode
Biochemical Pharmacology, 1987
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Synthesis and reactions of derivatives of 5-alkyl- and 5-halo-pyrimidines
Najim Al-Masoudi
Carbohydrate Research, 1995
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Steric Complementarity of Some Pyrimidine Derivatives with Active Sites of Mouse Thymidylate Synthase ( MUS Musculus )
Veronika Khayrullina
2016
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Interaction of the 5′-phosphates of the anti-hiv agents, 3′-azido-3′-deoxythymidine and 3′-azido-2′,3′-dideoxyuridine, with thymidylate synthase
Joanna Ciesla
Biochemical and Biophysical Research Communications, 1988
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Antiviral, antitumor, and thymidylate synthetase inhibition studies of 5-substituted styryl derivatives of 2′-deoxyuridine and their 5′-phosphates
Johan Descamps
Biochemical Pharmacology, 1981
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Sulfur Analogs of Pyrimidine Bases: Synthesis of 2-Alkylthio- and 4-Alkylthio-5-bromouracils and In Silico Evaluation of Their Biological Activity
Grażyna Bartkowiak
Journal of Heterocyclic Chemistry, 2013
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Synthesis and biological investigations of 5-substituted pyrimidine nucleosides coupled to a dihydropyridine/pyridinium salt redox chemical delivery system
Edward E Knaus
Archiv der Pharmazie, 2001
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Chemical synthesis of 4′-thio and 4′-sulfinyl pyrimidine nucleoside analogues
Mieke Guinan
Organic and Biomolecular Chemistryistry, 2021
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Enzymatic cleavage of 5-substituted-2'-deoxyuridines by pyrimidine nucleoside phosphorylases
I. Szinai
Biochemical Pharmacology, 1986
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The influence of the exocyclic pyrimidine 5-methyl group on DNAse I cleavage and sequence recognition by drugs
Christian BAILLY
Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression, 1999
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Synthesis, structure, and biological evaluation of C-2 sulfonamido pyrimidine nucleosides
Marija Luić, Biserka Žinić
Tetrahedron, 2003
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On the paradoxically concentration-dependent metabolism of 6-mercaptopurine in WEHI-3b murine leukemia cells
Pierre Lafolie
Cancer research, 1990
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Sulphonamide Antifolates Inhibiting Thymidylate Synthase. Synthesis, Enzyme Inhibition and Cytotoxicity
Wojciech Rode
Advances in Experimental Medicine and Biology, 1993
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Initial studies on the mechanism of action of a new oncolytic thiazole nucleoside, 2-β-d-ribofuranosylthiazole-4-carboxamide NSC 286193)
Bach Ardalan
Biochemical Pharmacology, 1982
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5‘-Phosphoramidates and 5‘-Diphosphates of 2‘-O-Allyl-β-d-arabinofuranosyl- uracil, -cytosine, and -adenine: Inhibition of Ribonucleotide Reductase
Stefano Manfredini
Journal of Medicinal Chemistry, 1999
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Metabolic effects of novel N-1-sulfonylpyrimidine derivatives on human colon carcinoma cells
Biserka Žinić
Farmacia Hospitalaria, 2005
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Studies on the mechanism of action of 2-β-d-ribofuranosylthiazole-4-carboxamide—V
Gurpreet Ahluwalia
Biochemical Pharmacology, 1984
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Inhibition of Microorganisms by Pyrimidine Nucleosides
Bipin Mehta
Annals of the New York Academy of Sciences, 1975
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Chemotherapeutic Characterization in Mice of 2-Amino-9-β-d-ribofuranosylpurine-6-sulfinamide (Sulfinosine), a Novel Purine Nucleoside with Unique Antitumor Properties
Rick Finch
Cancer Research, 1990
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Nucleosides of 1,4-thiazin-3-one and derivatives as tetrahedral intermediate analogs of enzymes in pyrimidine nucleoside metabolism
Corey Levenson
Journal of Medicinal Chemistry, 1988
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Inhibition of orotidylate decarboxylase by pyrimidine-3-thiocarboxamide (APR-TC) in B lymphoblasts
Donald Smee
Biochemical Pharmacology, 1988
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