Initial studies on the mechanism of action of a new oncolytic thiazole nucleoside, 2-β-d-ribofuranosylthiazole-4-carboxamide NSC 286193) (original) (raw)

Studies on the mechanism of action of 2-β-d-ribofuranosylthiazole-4-carboxamide—V

Gurpreet Ahluwalia

Biochemical Pharmacology, 1984

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Inhibition of pyrimidine metabolism in myeloid leukemia cells by triazole and pyrazole nucleosides

Yogesh Sanghvi

Biochemical Pharmacology, 1990

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Cytotoxicity and characterization of an active metabolite of benzamide riboside, a novel inhibitor of IMP dehydrogenase

Victor Marquez

International Journal of Cancer, 1994

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Inhibition of ribonucleotide reductase and growth of human colon carcinoma HT-29 cells and mouse leukemia L1210 cells by N-hydroxy-N′-aminoguanidine derivatives

Eric Lien

Biochemical Pharmacology, 1990

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Modulation of the cytotoxic mechanism of 6-thioguanine by 4-amino-5-imidazolecarboxamide

Catherine Morgans

Cancer Chemotherapy and Pharmacology, 1990

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Enhancement of the differentiation-inducing properties of 6-thioguanine by hypoxanthine and its nucleosides in HL-60 promyelocytic leukemia cells

Kimiko Ishiguro

Cancer Research

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CycloSal-phosphate Pronucleotides of Cytostatic 6-(Het)aryl-7-deazapurine Ribonucleosides: Synthesis, Cytostatic Activity, and Inhibition of Adenosine Kinases

Iva Pichová

ChemMedChem, 2010

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5‘-Phosphoramidates and 5‘-Diphosphates of 2‘-O-Allyl-β-d-arabinofuranosyl- uracil, -cytosine, and -adenine: Inhibition of Ribonucleotide Reductase

Stefano Manfredini

Journal of Medicinal Chemistry, 1999

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Mechanism of inhibition of DNA synthesis in Ehrlich ascites tumour cells by diazoacetyl glycine-amide

Tullio Giraldi

Biochemical Pharmacology, 1973

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Investigations into specificity of azepinomycin for inhibition of guanase: Discrimination between the natural heterocyclic inhibitor and its synthetic nucleoside analogues

Ramachandra Hosmane

Bioorganic & Medicinal Chemistry Letters, 2012

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Nucleoside and nucleotide modulation of genetic expression — A new approach to chemotherapy

Ganapathi Revankar

Advances in Enzyme Regulation, 1989

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Effects of the antitumor drugs 3-nitrobenzothiazolo {3,2-a}quinolinium and fagaronine on nucleic acid and protein synthesis

Adriana Báez

Biochemical Pharmacology, 1986

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Inhibition of poly(ADP-ribose)polymerase activity by nucleoside analogs of thymidine

Joanna Rzeszowska-wolny

Biochemical Pharmacology, 1992

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Effects of 8-aminoguanosine on the toxicity of guanosine and deoxyguanosine for malignant and normal lymphoid cells

Ronney Abreu

Journal of Leukocyte Biology

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7-(2-Thienyl)-7-deazaadenosine (AB61), a new potent nucleoside cytostatic with a complex mode of action

Petr Džubák

Molecular cancer therapeutics, 2016

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Evidence for the Involvement of Cytosolic 5′-Nucleotidase (cN-II) in the Synthesis of Guanine Nucleotides from Xanthosine

Rossana Pesi

Journal of Biological Chemistry, 2005

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Synthesis and biological studies of 3-(.beta.-D-ribofuranosyl)-2,3-dihydro-6H-1,3-oxazine-2,6-dione, a new pyrimidine nucleoside analog related to uridine

William F. Wood

Journal of Medicinal Chemistry, 1976

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Studies on the mechanism of 3-deazaguanine cytotoxicity in L1210-sensitive and -resistant cell lines

Bach Ardalan

Cancer Chemotherapy and Pharmacology, 1988

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Nucleosides of 1,4-thiazin-3-one and derivatives as tetrahedral intermediate analogs of enzymes in pyrimidine nucleoside metabolism

Corey Levenson

Journal of Medicinal Chemistry, 1988

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A novel N-hydroxy-N′-aminoguanidine derivative inhibits ribonucleotide reductase activity: Effects in human HL-60 promyelocytic leukemia cells and synergism with arabinofuranosylcytosine (Ara-C)

BN Sinha

Biochemical Pharmacology, 2011

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Studies on the mechanism of action of tiazofurin (2-β-d-ribofuranosylthiazole-4-carboxamide) VI

Gurpreet Ahluwalia

Biochemical Pharmacology, 1986

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Cell proliferation induced by 8-oxoguanosine and 8-methylguanosine, two adducts produced by free radical attack on ribonucleosides and RNA

Ohara Augusto

Chemico-Biological Interactions, 1998

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5-Formyluracil and its nucleoside derivatives confer toxicity and mutagenicity to mammalian cells by interfering with normal RNA and DNA metabolism

Svein Bjelland

Toxicology Letters, 2001

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Synergistic enhancement of 6-thioguanine cytotoxicity by ADP-ribosyltransferase inhibitors

Barbara Durkacz

Cancer research, 1988

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Modulation of the metabolism of beta-L-(-)-2',3'-dideoxy-3'-thiacytidine by thymidine, fludarabine, and nitrobenzylthioinosine

D Lorne Tyrrell

Antimicrobial Agents and Chemotherapy, 1997

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Synthesis and biochemical evaluation of guanidino-alkyl-ribitol derivatives as nucleoside hydrolase inhibitors

Koen Augustyns

European Journal of Medicinal Chemistry, 2008

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Synthesis and biological activity of 5-fluoro-4'-thiouridine and some related nucleosides

Sp Dutta

Journal of Medicinal Chemistry, 1975

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Biochemical Properties of 5‐SULFUR‐SUBSTITUTED Pyrimidine Nucleosides and Nucleotides*

János Aradi

Annals of the New York Academy of Sciences, 1975

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Chemo-Enzymatic Synthesis and Biological Evaluation of 5,6-Disubstituted Benzimidazole Ribo- and 2′-Deoxyribonucleosides

Igor Mikhailopulo

Synthesis, 2012

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On the interactions of indazole derivative with nucleosides - towards modeling the cytotoxic activity mechanism

Marek Doskocz

Computational and Theoretical Chemistry, 2015

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Nucleosides XCI. Some Chemical Properties of the Antileukemic Agent 2,2'-ANHYDRO-1-?-D-ARABINOFURANOSYL-5-FLUOROCYTOSINE

B. Otter

Annals of the New York Academy of Sciences, 1975

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