The DNA Helicase Activity of BLM Is Necessary for the Correction of the Genomic Instability of Bloom Syndrome Cells (original) (raw)

Cell cycle regulation of the endogenous wild type Bloom's syndrome DNA helicase

Bruno Chatton, Jozo Delic

Oncogene, 2000

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Point mutations causing Bloom's syndrome abolish ATPase and DNA helicase activities of the BLM protein

Bruno Chatton

Oncogene, 1998

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Bloom helicase is involved in DNA surveillance in early S phase in vertebrate cells

Akira Shimamoto

Oncogene, 2001

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Regulation and localization of the Bloom syndrome protein in response to DNA damage

Judith Campisi

The Journal of cell …, 2001

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Transfection of BLM into Cultured Bloom Syndrome Cells Reduces the Sister-Chromatid Exchange Rate toward Normal

Tianzhang Ye

The American Journal of Human Genetics, 1999

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Processive translocation mechanism of the human Bloom's syndrome helicase along single-stranded DNA

Kata Sarlós

Nucleic acids research, 2010

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Dephosphorylation and Subcellular Compartment Change of the Mitotic Bloom's Syndrome DNA Helicase in Response to Ionizing Radiation

lionel tintignac

Journal of Biological Chemistry, 2002

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Increased error-prone non homologous DNA end-joining – a proposed mechanism of chromosomal instability in Bloom's syndrome

Terry Gaymes

Oncogene, 2002

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Possible anti-recombinogenic role of Bloom's syndrome helicase in double-strand break processing

Bernard Salles

Nucleic Acids Research, 2003

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Control of Translocations between Highly Diverged Genes by Sgs1, the Saccharomyces cerevisiae Homolog of the Bloom's Syndrome Protein

Joan Wu

Molecular and Cellular Biology, 2006

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The Bloom's syndrome gene product is homologous to RecQ helicases

Tianzhang Ye

Cell, 1995

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The Bloom's Syndrome Protein (BLM) Interacts with MLH1 but Is Not Required for DNA Mismatch Repair

Kathleen Goss

Journal of Biological Chemistry, 2001

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Phosphorylation of the Bloom's Syndrome Helicase and Its Role in Recovery from S-Phase Arrest

Alwyn Dart

Molecular and Cellular Biology, 2004

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Structural basis of Bloom syndrome (BS) causing mutations in the BLM helicase domain

Jouni Väliaho

Molecular medicine (Cambridge, Mass.), 2000

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BLAP75, an essential component of Bloom's syndrome protein complexes that maintain genome integrity

CHANG XU

Embo Journal, 2005

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SGSl, a Homologue of the Bloom's and Werner's Syndrome Genes, Is Required for Maintenance of Genome Stability in Saccharomyces cereuiSiae

Edward Louist, Paul Watt

2000

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Direct association of Bloom's syndrome gene product with the human mismatch repair protein MLH1

Igor Stagljar

Nucleic Acids Research, 2001

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Mitotic phosphorylation of Bloom helicase at Thr182 is required for its proteasomal degradation and maintenance of chromosomal stability

Vivek Srivastava

Oncogene, 2015

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Implications of somatic recombination and sister chromatid exchange in Bloom's syndrome and cells treated with mitomycin C

David Comings

Human Genetics, 1975

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Chromosomal instability associated with a novel BLM frameshift mutation (c.1980-1982delAA) in two unrelated Tunisian families with Bloom syndrome

F. Fakhfakh

Journal of the European Academy of Dermatology and Venereology, 2013

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A role for PML and the nuclear body in genomic stability

Tianzhang Ye

Oncogene, 1999

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Visualization of human Bloom's syndrome helicase molecules bound to homologous recombination intermediates

Mihály Kovács

The FASEB Journal, 2013

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Bloom's and Werner's syndrome genes suppress hyperrecombination in yeast sgs1 mutant: Implication for genomic instability in human diseases

Akira Shimamoto

Proceedings of the National Academy of Sciences, 1998

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A Small Molecule Inhibitor of the BLM Helicase Modulates Chromosome Stability in Human Cells

Csanad Z. Bachrati, Giang Nguyen

Chemistry & Biology, 2013

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Complex activities of the human Bloom's syndrome helicase are encoded in a core region comprising the RecA and Zn-binding domains

Kata Sarlós

Nucleic Acids …, 2012

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Mobile D-loops are a preferred substrate for the Bloom's syndrome helicase

Csanad Z. Bachrati, Rhona Borts

Nucleic Acids Research, 2006

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The distribution and expression of the Bloom's syndrome gene product in normal and neoplastic human cells

Marta Canamero

British journal of cancer, 2001

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Ubiquitin-dependent recruitment of the Bloom Syndrome helicase upon replication stress is required to suppress homologous recombination

Priyanka Modi

The EMBO Journal, 2013

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Stability of microsatellites and minisatellites in Bloom syndrome, a human syndrome of genetic instability

F. Praz

Mutation Research/DNA Repair, 1996

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Mechanisms by Which Bloom Protein Can Disrupt Recombination Intermediates of Okazaki Fragment Maturation

Jeremy Bartos

Journal of Biological Chemistry, 2006

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Genome stability: Failure to unwind causes cancer

Paul Watt

Current Biology, 1996

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Protease inhibitors reduce the frequency of spontaneous chromosome abnormalities in cells from patients with Bloom syndrome

Ann Kennedy

Proceedings of the National Academy of Sciences, 1984

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Binding and Melting of D-Loops by the Bloom Syndrome Helicase

Tianzhang Ye

Biochemistry, 2000

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