Interaction of muscarinic acetylcholine receptors and three kinds of GTP-binding proteins (Gi, Go and Gn) purified from porcine cerebrum and atrium (original ) (raw )Dual regulation by G proteins of agonist-dependent phosphorylation of muscarinic acetylcholine receptors
T. Haga
FEBS Letters, 1990
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Haga, K., Haga, T. & Ichiyama, A. Reconstitution of the muscarinic acetylcholine receptor. Guanine nucleotide-sensitive high affinity binding of agonists to purified muscarinic receptors reconstituted with GTP-binding proteins (Gi and Go). J. Biol. Chem. 261, 10133-10140
T. Haga
Journal of Biological Chemistry
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Phosphorylation of muscarinic receptors: regulation by G proteins
T. Haga
Life Sciences, 1993
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Phosphorylation by Protein Kinase C of the Muscarinic Acetylcholine Receptor
T. Haga
Journal of Neurochemistry, 1990
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Distinct sequence elements control the specificity of G protein activation by muscarinic acetylcholine receptor subtypes
D Clapham
The EMBO Journal, 1990
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Characterization of M 2 muscarinic receptor activation of different G protein subtypes
Karl Åkerman
Neurochemistry International, 2004
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G-protein mediates voltage regulation of agonist binding to muscarinic receptors: effects on receptor-sodium channel interaction
Malka Cohen-Armon
Biochemistry, 1988
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Preservation of acetylcholine muscarinic M2 receptor G-protein interactions 1995
Abdu Adem
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Activation of a GTP-Binding Protein and a GTP-Binding-Protein-Coupled Receptor Kinase (beta-Adrenergic-Receptor Kinase-1) by a Muscarinic Receptor m2 Mutant Lacking Phosphorylation Sites
T. Haga
European Journal of Biochemistry, 1994
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Agonist and Antagonist Binding of Muscarinic Acetylcholine Receptors Purified from Porcine Brain: Interconversion of High- and Low-Affinity Sites by Sulfhydryl Reagents
T. Haga
Journal of Neurochemistry, 1988
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Functional interaction of purified muscarinic receptors with purified inhibitory guanine nucleotide regulatory proteins reconstituted in phospholipid vesicles
T. Haga
The Journal of biological chemistry, 1986
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Binding characteristics and functional G protein coupling of muscarinic acetylcholine receptors in rat duodenum smooth muscle membranes
Martin Schnittler
Naunyn-Schmiedeberg's Archives of Pharmacology, 1992
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Regulation of muscarinic receptor binding by guanine nucleotides and N-ethylmaleimide
Frederick Ehlert
Journal of supramolecular structure, 1980
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Purification of the muscarinic acetylcholine receptor from porcine atria
T. Haga
Proceedings of the National Academy of Sciences, 1984
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Phosphorylation of Human m1 Muscarinic Acetylcholine Receptors by G Protein-coupled Receptor Kinase 2 and Protein Kinase C
T. Haga
Journal of Biological Chemistry, 1996
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Activation by G protein βγ subunits of β-adrenergic and muscarinic receptor kinase
T. Haga
Journal of Biological Chemistry
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A heterotrimeric G protein complex couples the muscarinic m1 receptor to phospholipase C-beta
Burghardt Wittig
Proceedings of the National Academy of Sciences, 1996
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Immunochemical Studies of the Muscarinic Acetylcholine Receptor
Stefano Marullo
Journal of Receptors and Signal Transduction, 1987
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Recognition of the muscarinic receptor by its endogenous neurotransmitter: binding of [3H]acetylcholine and its modulation by transition metal ions and guanine nucleotides
David Gurwitz
Proceedings of the National Academy of Sciences, 1984
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Agonist binding to M1 muscarinic receptors is sensitive to guanine nucleotides
nick palermo
European Journal of Pharmacology: Molecular Pharmacology, 1989
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GTP-binding proteins mediate the M2-muscarinic effect on the action potential in isolated sympathetic neurons of rabbits
Sumiko Mochida
Neuroscience Letters, 1988
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Sequestration of muscarinic acetylcholine receptor m2 subtypes. Facilitation by G protein-coupled receptor kinase (GRK2) and attenuation by a dominant-negative mutant of GRK2
T. Haga
The Journal of biological chemistry, 1994
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Location of agonist-dependent-phosphorylation sites in the third intracellular loop of muscarinic acetylcholine receptors (m2 subtype)
T. Haga
European Journal of Biochemistry, 1994
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Cardiac muscarinic receptor binding is regulated by Na+ and guanine nucleotides
William Roeske
Journal of Biological Chemistry
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Activation and allosteric modulation of a muscarinic acetylcholine receptor
Peter Gmeiner
Nature, 2013
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Subtype Differences in Pre-Coupling of Muscarinic Acetylcholine Receptors
Vladimír Doležal
PLoS ONE, 2011
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Affinity chromatography of the muscarinic acetylcholine receptor
T. Haga
The Journal of biological chemistry, 1983
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Regulation of Muscarinic Acetylcholine Receptor Expression and Functiona
Jacques Migeon
Annals of the New York Academy of Sciences, 1995
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Selective activation of heterologously expressed G protein-gated K+ channels by M2 muscarinic receptors in rat sympathetic neurones
Malcolm Caulfield , J. Fernandez
The Journal of Physiology, 1999
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Muscarinic Receptors—Characterization, coupling and function
Malcolm Caulfield
Pharmacology & Therapeutics, 1993
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Helix 8 of the M1 Muscarinic Acetylcholine Receptor: Scanning Mutagenesis Delineates a G Protein Recognition Site
José Saldanha
Molecular Pharmacology, 2011
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Mechanism of muscarinic receptor-induced K+ channel activation as revealed by hydrolysis-resistant GTP analogues
Gerda Breitwieser
The Journal of General Physiology, 1988
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Molecular size of muscarinic acetylcholine receptors of rat brain
T. Haga
FEBS Letters, 1980
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IUPHAR XVII. Classification of muscarinic acetylcholine receptors
Malcolm Caulfield
Pharmacological Reviews
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Muscarinic acetylcholine receptors: novel opportunities for drug development
Dinesh Gautam
Nature Reviews Drug Discovery, 2014
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