n-Decyl-NHpppA2′p5′A2′p5′A a phosphatase-resistant, active pppA2′p5′A2′p5′A analog (original) (raw)

Analogues and Analogue Inhibitors of ppp(A2'p)nA. Their Stability Biological Activity

David Norman

European Journal of Biochemistry, 1983

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Enzymic Synthesis, Characterisation and Nuclear-Magnetic-Resonance Spectra of pppA2'p5'A2'p5'A and Related Oligonucleotides: Comparison with Chemically Synthesised Material

Ronald Brown

European Journal of Biochemistry, 1979

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Enzymatic synthesis of the 2′,5′-A4 tetramer analog, 2′,5′-ppp3′dA(p3′dA)3, by rabbit reticulocyte lysates: Binding and activation of the 2′,5′-An dependent nuclease, hydrolysis of mRNA, and inhibition of protein synthesis

Yair Devash

Biochemical and Biophysical Research Communications, 1983

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The 100-kDa 2',5'-Oligoadenylate Synthetase Catalyzing Preferentially the Synthesis of Dimeric pppA2'p5'A Molecules Is Composed of Three Homologous Domains

Dominique Rebouillat

Journal of Biological Chemistry, 1999

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Novel diadenosine polyphosphate analogs with oxymethylene bridges replacing oxygen in the polyphosphate chain

G. Blackburn, Andrzej Guranowski

FEBS Journal, 2009

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Cordycepin analogs of ppp5'A2'p5'A2'p5'A (2-5A) inhibit protein synthesis through activation of the 2-5A-dependent endonuclease

Marjorie van der Pas, Deborah Eppstein

Journal of Biological Chemistry

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Inhibition of phosphoribosylpyrophosphate synthetase by 4-methoxy-(MRPP) and 4-amino-8-(d-ribofuranosylamino)pyrimido[5,4-d]pyrimidine (ARPP)

Yogesh Sanghvi

Biochemical Pharmacology, 1989

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Synthesis and Breakdown of pppA2'p5'A2'p5'A and Transient Inhibition of Protein Synthesis in Extracts from Interferon-Treated and Control Cells

L. Andrew Ball

European Journal of Biochemistry, 1978

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Synthesis and biological activities of a phosphorodithioate analog of 2′, 5′-oligoadenylate

Peter Haeberli

Nucleic Acids Research, 1995

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Phosphorothioate analogs of (2'-5')(A)4: agonist and antagonist activities in intact cells

Catherine Armande Bisbal

Biochemistry, 1990

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Enzymatic synthesis of mono and dinucleoside polyphosphates

Hugo Fraga, Rui Fontes

Biochimica et Biophysica Acta (BBA) - General Subjects, 2011

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[25] Enzymatic regeneration of adenosine 5′-triphosphate: Acetyl phosphate, phosphoenolpyruvate, methoxycarbonyl phosphate, dihydroxyacetone phosphate, 5-phospho-α-d-ribosyl pyrophosphate, uridine-5′-diphosphoglucose

Debbie Crans

Immobilized Enzymes and Cells, Part C, 1987

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Insoluble derivatives of polynucleotide-phosphorylase

English Learning

FEBS Letters, 1973

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Synthesis of cell-impermeable inhibitor of phospholipase A2

Arie Dagan

FEBS Letters, 1986

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An Enzymatic Procedure for the Preparation and Purification of 3′-Phosphoadenosine 5′-Phospho- [35S]Sulfate ([35S]PAPS): Applications in Syntheses of 8-Azido and 8-Bromo Derivatives of [35S]PAPS

Kunwar Shailubhai

Analytical Biochemistry, 1996

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Methodology for synthesis and isolation of 5-phosphomevalonic acid

Henry Miziorko

Analytical Biochemistry, 2003

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Use of Penetrating Peptides Interacting with PP1/PP2A Proteins As a General Approach for a Drug Phosphatase Technology

Victor J Yuste

Molecular Pharmacology, 2006

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Synthesis of acyl pyrophosphates. Application to the synthesis of nucleotide lipophilic prodrugs

Huynh Đinh

Tetrahedron Letters, 1995

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J. Med.Chem. 1994, 37, 3969-3976.pdf

Bogdan Boduszek

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Amino Acid Phosphoramidate Nucleotides as Alternative Substrates

Olga Adelfinskaya

… Chemie (International ed.), 2007

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Synthesis and Biological Properties of Enzyme-Resistant Analogues of Substance P

chi ming lee

European Journal of Biochemistry, 1981

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Nonhydrolysable Analogues of (p)ppGpp and (p)ppApp Alarmone Nucleotides as Novel Molecular Tools

Duy Do Pham

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Carbocyclic analogues of d-ribose-5-phosphate: Synthesis and behavior with 5-phosphoribosyl α-1-pyrophosphate synthetases

Ronald Parry

Bioorganic & Medicinal Chemistry, 1996

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Preparative enzymic synthesis and isolation of d-threo-2-pentulose 5-phosphate (d-xylulose 5-phosphate)

Alessandra Mocali

Carbohydrate Research, 1985

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Synthesis of an unnatural P-N bond catalyzed with Escherichia coli ribosomes

Marina Kukhanova

FEBS Letters, 1981

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N-(Cyclohexanecarboxyl)-O-Phospho--Serine, a Minimal Substrate for the Dual-Specificity Protein Phosphatase IphP

Richard Gandour

Archives of Biochemistry and Biophysics, 2000

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Substrate-Assisted Catalysis by PARP10 Limits Its Activity to Mono-ADP-Ribosylation

Brian Shilton

Molecular Cell, 2008

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Probing the Stereochemistry of E. coli 3-Deoxy- d - arabino -heptulosonate 7-Phosphate Synthase (Phenylalanine-Sensitive)-Catalyzed Synthesis of KDO 8-P Analogues

Ronald Woodard

The Journal of Organic Chemistry, 2000

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Phosphonate analogs of diadenosine 5',5'''-P1,P4-tetraphosphate as substrates or inhibitors of prokaryotic and eukaryotic enzymes degrading dinucloside tetraphosphates

Radii Khomutov

Biochemistry, 1987

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Synthesis and enzymatic evaluation of the guanosine analogue 2-amino-6-mercapto-7-methylpurine ribonucleoside (MESG): insights into the phosphorolysis reaction mechanism based on the blueprint transition state: SN1 or S N2?

Luiz Basso

Journal of the Brazilian Chemical Society, 2010

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The synthesis and reactivity of new 2-( N, N-diisopropylamino)-3-methylsulfonyl-1,3,2-benzoxazaphospholes. The utility of the 5-chloro analogue in the one-pot synthesis of oligothiophosphates: [Ap sppA, Ap spppA, ppp5′A2′p s5′A, m 7Gp sppA, Ap spppp, Ap spp

Nitin Puri

Tetrahedron, 1995

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Effects of substitution of the absolutely invariant Gln-4 and Phe-5 in bovine pancreatic phospholipase A2 on enzymic activity and substrate binding properties

Guus van Scharrenburg

Biochemistry, 1982

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