Novel diadenosine polyphosphate analogs with oxymethylene bridges replacing oxygen in the polyphosphate chain (original) (raw)

Selective degradation of 2'-adenylated diadenosine tri- and tetraphosphates, Ap(3)A and Ap(4)A, by two specific human dinucleoside polyphosphate hydrolases

Andrzej Guranowski

Archives of biochemistry and biophysics, 2000

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Phosphonate analogs of diadenosine 5',5'''-P1,P4-tetraphosphate as substrates or inhibitors of prokaryotic and eukaryotic enzymes degrading dinucloside tetraphosphates

Radii Khomutov

Biochemistry, 1987

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Phosphorothioate analogues of 2',5'-oligoadenylate. Enzymatic synthesis, properties, and biological activities of 2',5'-phosphorothioates from adenosine 5'-O-(2-thiotriphosphate) and adenosine 5'-O-(3-thiotriphosphate)

Nancy Reichenbach, Wolfgang Pfleiderer

Biochemistry, 1987

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The pro-oligonucleotide approach. V: Influence of the phosphorus atom environment on the hydrolysis of enzymolabile dinucleoside phosphotriesters

Francois Morvan

Bioorganic & Medicinal Chemistry Letters, 1997

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Enzymatic synthesis of mono and dinucleoside polyphosphates

Hugo Fraga, Rui Fontes

Biochimica et Biophysica Acta (BBA) - General Subjects, 2011

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Amino Acid Phosphoramidate Nucleotides as Alternative Substrates

Olga Adelfinskaya

… Chemie (International ed.), 2007

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n-Decyl-NHpppA2′p5′A2′p5′A a phosphatase-resistant, active pppA2′p5′A2′p5′A analog

Janos Ludwig

Biochemical and Biophysical Research Communications, 1985

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Influence of the Nucleobase and Anchimeric Assistance of the Carboxyl Acid Groups in the Hydrolysis of Amino Acid Nucleoside Phosphoramidates

Arnout Ceulemans

Chemistry - A European Journal, 2011

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Synthesis of diadenosine 5',5'''-P1,P4-tetraphosphate (AppppA) from adenosine 5'-phosphosulfate and adenosine 5'-triphosphate catalyzed by yeast AppppA phosphorylase

Andrzej Guranowski

Biochemistry, 1988

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Synthesis of a Biologically Important Adenosine Triphosphate Analogue, ApppD

Petri Turhanen

ACS omega, 2017

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[25] Enzymatic regeneration of adenosine 5′-triphosphate: Acetyl phosphate, phosphoenolpyruvate, methoxycarbonyl phosphate, dihydroxyacetone phosphate, 5-phospho-α-d-ribosyl pyrophosphate, uridine-5′-diphosphoglucose

Debbie Crans

Immobilized Enzymes and Cells, Part C, 1987

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Design and synthesis of phosphonoacetic acid (PPA) ester and amide bioisosters of ribofuranosylnucleoside diphosphates as potential ribonucleotide reductase inhibitors and evaluation of their enzyme inhibitory, cytostatic and antiviral activity

Angela Angusti

Antiviral Chemistry Chemotherapy, 2003

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Targeting 5'-deoxy-5'-(methylthio)adenosine phosphorylase by 5'-haloalkyl analogs of 5'-deoxy-5'-(methylthio)adenosine

Carl Porter

Journal of Medicinal Chemistry, 1991

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5′,6′-Nucleoside Phosphonate Analogues Architecture: Synthesis and Comparative Evaluation towards Metabolic Enzymes

Chahrazade Amri

ChemMedChem, 2011

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Synthesis and biological activities of a phosphorodithioate analog of 2′, 5′-oligoadenylate

Peter Haeberli

Nucleic Acids Research, 1995

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The enzymatic hydrolysis of the phosphate ester bond in some thionucleotides

Joseph Nagyvary

Biochimica et biophysica acta, 1979

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Insights into Phosphate Cooperativity and Influence of Substrate Modifications on Binding and Catalysis of Hexameric Purine Nucleoside Phosphorylases

Mario Murakami, P. Giuseppe, Camila Ramos Santos

PLoS ONE, 2012

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New Tripodal, “Supercharged” Analogues of Adenosine Nucleotides: Inhibitors for the Fhit Ap3A Hydrolase

Charles Brenner

Angewandte Chemie International Edition, 1999

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Reconstitution of apophosphorylase with pyridoxal 5'-phosphate analogs

Jery Hedrick

Biochemistry, 1969

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Anopheles gambiae Purine Nucleoside Phosphorylase: Catalysis, Structure, and Inhibition

Mahmoud Ghanem

Biochemistry, 2007

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Prospecting for Unannotated Enzymes: Discovery of a 3′,5′-Nucleotide Bisphosphate Phosphatase within the Amidohydrolase Superfamily

Swapnil Ghodge

Biochemistry, 2014

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2'-Deoxynucleoside 5'-triphosphates modified at alpha-, beta- and gamma- phosphates as substrates for DNA polymerases

Alexander Skoblov

Nucleic Acids Research, 1998

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3-Acetyloxy-2-cyano-2-(alkylaminocarbamoyl)propyl Groups as Biodegradable Protecting Groups of Nucleoside 5´-mono-Phosphates

Harri Lonnberg

Molecules, 2011

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Structural basis of the inhibition of class C acid phosphatases by adenosine 5;#8242;-phosphorothioate

harkewal singh

2012

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Functionalized Oxoindolin Hydrazine Carbothioamide Derivatives as Highly Potent Inhibitors of Nucleoside Triphosphate Diphosphohydrolases

Saira Afzal

Frontiers in Pharmacology, 2020

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The Practical Synthesis of a Methylenebisphosphonate Analogue of Benzamide Adenine Dinucleotide: Inhibition of Human Inosine Monophosphate Dehydrogenase (Type I and II) 1

Andrzej Zatorski

Journal of Medicinal Chemistry, 1997

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cyclo-Diphosphates as intermediates in reactions of nucleoside phosphorothioates with cyanogen bromide

Douglas Sammons

Journal of the American Chemical Society, 1984

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A novel adenosine triphosphate analog with a heavy atom to target the nucleotide binding site of proteins

Nariman Naber

Protein Science, 1995

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Recombinant purine nucleoside phosphorylases from thermophiles: preparation, properties and activity towards purine and pyrimidine nucleosides

Peter Neubauer

FEBS Journal, 2013

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Practical enzymic synthesis of adenosine 5'-0-(3-thiotriphosphate) (ATP.gamma.-S)

Debbie Crans

The Journal of Organic …, 1984

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3' Esters of ADP as Energy-Transfer Inhibitors and Probes of the Catalytic Site of Oxidative Phosphorylation

Günes Onur

European Journal of Biochemistry, 1979

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