The down side of glucocorticoid receptor regulation (original) (raw)

Autoregulation of glucocorticoid receptor gene expression

Steroids, 1991

Molecular basis of glucocorticoid action

Srpski arhiv za celokupno lekarstvo, 2005

Differential Hormone-Dependent Transcriptional Activation and -Repression by Naturally Occurring Human Glucocorticoid Receptor Variants

George P Chrousos

Molecular Endocrinology, 1997

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Molecular genetic dissection of glucocorticoid receptor function in vivo

J. Tuckermann

Zeitschrift für Rheumatologie, 2000

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Human glucocorticoid receptor cDNA contains sequences sufficient for receptor down-regulation

John Cidlowski

Journal of Biological Chemistry, 1990

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A Novel Point Mutation in the Ligand-Binding Domain (LBD) of the Human Glucocorticoid Receptor (hGR) Causing Generalized Glucocorticoid Resistance: The Importance of the C Terminus of hGR LBD in Conferring Transactivational Activity

George P Chrousos

The Journal of Clinical Endocrinology & Metabolism, 2005

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Modulation of transcription parameters in glucocorticoid receptor-mediated repression

Yunguang Sun, Stoney Simons

Molecular and Cellular Endocrinology, 2008

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A Fraction Enriched in a Novel Glucocorticoid Receptor-interacting Protein Stimulates Receptor-dependent Transcription in Vitro

M. Beato

Journal of Biological Chemistry, 1995

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Differential gene induction by glucocorticoid and progesterone receptors

Steven Nordeen

The Journal of Steroid Biochemistry and Molecular Biology, 1998

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Twenty-First Century Glucocorticoid Receptor Molecular Biology

Colin Logie

Corticosteroids, 2018

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The human glucocorticoid receptor: Molecular basis of biologic function

Nicolas Nicolaides

Steroids, 2010

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Purified glucocorticoid receptors bind selectively in vitro to a cloned DNA fragment whose transcription is regulated by glucocorticoids in vivo

Sam Okret

Proceedings of the National Academy of Sciences, 1981

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Overexpressed glucocorticoid receptor negatively regulates gene expression under conditions that favour accumulation of non-hormone-binding forms of the receptor

Dimitra Mitsiou

The Journal of Steroid Biochemistry and Molecular Biology, 2003

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A Novel Point Mutation in Helix 11 of the Ligand-Binding Domain of the Human Glucocorticoid Receptor Gene Causing Generalized Glucocorticoid Resistance

liliana mejia, Evangelia Charmandari

The Journal of Clinical Endocrinology & Metabolism, 2007

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Human glucocorticoid receptor gene promotor—homologous down regulation

Palaniswami Rathanaswami

The Journal of Steroid Biochemistry and Molecular Biology, 1991

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Mechanism of gene expression by the glucocorticoid receptor: Role of protein-protein interactions

Iain McEwan

BioEssays, 1997

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The Glucocorticoid Receptor: Coding a Diversity of Proteins and Responses through a Single Gene

John Cidlowski

Molecular Endocrinology, 2002

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Glucocorticoid receptor control of transcription: precision and plasticity via allostery

Eric Ortlund

Nature Reviews Molecular Cell Biology

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Molecular mechanisms regulating glucocorticoid sensitivity and resistance

John Cidlowski

Molecular and Cellular Endocrinology, 2009

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Glucocorticoid receptor (GR) β has intrinsic, GRα-independent transcriptional activity

George P Chrousos

Biochemical and Biophysical Research Communications, 2009

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The human glucocorticoid receptor: One gene, multiple proteins and diverse responses

John Cidlowski

Steroids, 2005

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A trilogy of glucocorticoid receptor actions

CHEK KUN TAN

Proceedings of the National Academy of Sciences of the United States of America, 2016

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A Novel Point Mutation of the Human Glucocorticoid Receptor Gene Causes Primary Generalized Glucocorticoid Resistance Through Impaired Interaction With the LXXLL Motif of the p160 Coactivators: Dissociation of the Transactivating and Transreppressive Activities

George P Chrousos, Nicolas Nicolaides

The Journal of Clinical Endocrinology & Metabolism, 2014

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Acquired Glucocorticoid Resistance Due to Homologous Glucocorticoid Receptor Downregulation: A Modern Look at an Age-Old Problem

lee-maine spies

Cells

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Mutational Analysis of the Mouse Glucocorticoid Receptor

Mark Danielsen

Cancer Research, 1989

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Regulation of the human glucocorticoid receptor by long-term and chronic treatment with glucocorticoid

John Cidlowski

Steroids, 1994

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Transactivation Specificity of Glucocorticoid VersusProgesterone Receptors

Sandro Rusconi

Journal of Biological Chemistry, 2001

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Evidence for a Common Step in Three Different Processes for Modulating the Kinetic Properties of Glucocorticoid Receptor-induced Gene Transcription

Stoney Simons

Journal of Biological Chemistry, 2000

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Translational Regulatory Mechanisms Generate N-Terminal Glucocorticoid Receptor Isoforms with Unique Transcriptional Target Genes

John Cidlowski

Molecular Cell, 2005

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A natural sequence consisting of overlapping glucocorticoid-responsive elements mediates glucocorticoid, but not androgen, regulation of gene expression

Michèle Garlatti

Biochemical Journal, 2000

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Glucocorticoid receptor physiology

Edwin Sanchez

Reviews in Endocrine and Metabolic Disorders, 2007

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Glucocorticoid Receptor Phosphorylation Differentially Affects Target Gene Expression

Dang Thoa

Molecular Endocrinology, 2008

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The down side of glucocorticoid receptor regulation (original) (raw)

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