RGS9-Gβ5 Substrate Selectivity in Photoreceptors (original) (raw)
RGS9-Gbeta 5 Substrate Selectivity in Photoreceptors. OPPOSING EFFECTS OF CONSTITUENT DOMAINS YIELD HIGH AFFINITY OF RGS INTERACTION WITH THE G PROTEIN-EFFECTOR COMPLEX
Nikolai Skiba
J Biol Chem, 2001
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The effector enzyme regulates the duration of G protein signaling in vertebrate photoreceptors by increasing the affinity between transducin and RGS protein
Nikolai Skiba
The Journal of biological chemistry, 2000
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The GTPase activating factor for transducin in rod photoreceptors is the complex between RGS9 and type 5 G protein subunit
elina makino
Proceedings of the National Academy of Sciences, 1999
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The GTPase activating factor for transducin in rod photoreceptors is the complex between RGS9 and type 5 G protein β subunit
Jason Handy
Proceedings of the National Academy of Sciences, 1999
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A Possible Role of RGS9 in Phototransduction. A BRIDGE BETWEEN THE cGMP-PHOSPHODIESTERASE SYSTEM AND THE GUANYLYL CYCLASE SYSTEM
Fumio Hayashi
Journal of Biological Chemistry, 1998
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Modules in the Photoreceptor RGS9-1· Gβ 5L GTPase-accelerating Protein Complex Control Effector Coupling, GTPase Acceleration, Protein Folding, and Stability
Wei He
2000
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N-terminal Half of the cGMP Phosphodiesterase -Subunit Contributes to Stabilization of the GTPase-accelerating Protein Complex
Lian-wang Guo, Arnold Ruoho
Journal of Biological Chemistry, 2011
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The N Terminus of GTPγS-activated Transducin α-Subunit Interacts with the C Terminus of the cGMP Phosphodiesterase γ-Subunit
Arnold Ruoho
Journal of Biological Chemistry, 2006
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Interactions of a G-protein with its effector: transducin and cGMP phosphodiesterase in retinal rods
P. Deterre
Cellular Signalling, 1993
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R9AP, a membrane anchor for the photoreceptor GTPase accelerating protein, RGS9-1
Theodore Wensel
Proceedings of the National Academy of Sciences, 2002
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G protein-effector coupling: interactions of recombinant inhibitory γ-subunit with transducin and phosphodiesterase
Debora Farber
Biochemistry, 1989
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G protein-effector coupling: interactions of recombinant inhibitory .gamma. subunit with transducin and phosphodiesterase
Debora Farber
Biochemistry, 1989
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RGS9, a GTPase Accelerator for Phototransduction
Theodore Wensel
Neuron, 1998
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Role for the target enzyme in deactivation of photoreceptor G protein in vivo
Peter Calvert
Science (New York, N.Y.), 1998
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The DEP domain determines subcellular targeting of the GTPase activating protein RGS9 in vivo
Polina Lishko
The Journal of neuroscience : the official journal of the Society for Neuroscience, 2003
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Binding of cGMP to the transducin-activated cGMP phosphodiesterase, PDE6, initiates a large conformational change involved in its deactivation
Fumio Hayashi
FEBS Journal, 2011
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Transducin activates cGMP phosphodiesterase by trapping inhibitory γ subunit freed reversibly from the catalytic subunit in solution
Satoru Kawamura
Scientific Reports
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Activation of RGS9-1GTPase Acceleration by Its Membrane Anchor, R9AP
Theodore Wensel
Journal of Biological Chemistry, 2003
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GTP‐dependent binding of Gi, Go and Gs to the γ‐subunit of the effector of Gt
Minh Vương
FEBS Letters, 1994
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A concept for G protein activation by G protein-coupled receptor dimers: the transducin/rhodopsin interface
Andreas Engel
Photochemical & Photobiological Sciences, 2004
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A Constitutively Active Gα Subunit Provides Insights into the Mechanism of G Protein Activation
Garima Singh
Biochemistry, 2012
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High expression levels in cones of RGS9, the predominant GTPase accelerating protein of rods
Theodore Wensel
Proceedings of the National Academy of Sciences, 1998
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Different Properties of the Native and Reconstituted Heterotrimeric G Protein Transducin †
Thomas Angel, Beata Jastrzebska
Biochemistry, 2008
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The molecular architecture of photoreceptor phosphodiesterase 6 (PDE6) with activated G protein elucidates the mechanism of visual excitation
Feixia Chu
Journal of Biological Chemistry, 2019
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Participation of RGS8 in the ternary complex of agonist, receptor and G-protein
Amy Benians
Biochemical Society Transactions 32 1045 1047, 2004
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The N-terminal Domain of RGS4 Confers Receptor-selective Inhibition of G Protein Signaling
Serguei Popov
Journal of Biological Chemistry, 1998
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Timing Is Everything: GTPase Regulation in Phototransduction
Theodore Wensel
Investigative Opthalmology & Visual Science, 2013
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G Protein Selectivity Is a Determinant of RGS2 Function
Sp Henny, Sreesha Srinivasa
Journal of Biological Chemistry, 1999
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Structural Analysis of the Regulatory GAF Domains of cGMP Phosphodiesterase Elucidates the Allosteric Communication Pathway
Feixia Chu
Journal of Molecular Biology, 2020
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