Identifying pathways involved in leptin-dependent aggregation of human platelets (original) (raw)
Leptin-dependent platelet aggregation in healthy, overweight and obese subjects
Francesco Perticone
2003
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Aggregation-dependent signaling in human platelets is sensitive to protein serine/threonine phosphatase inhibitors
Christopher Hoyt
Biochemistry, 1995
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Leptin Does Not Play a Major Role in Platelet Aggregation in Obesity and Leptin Deficiency
Özlem Durmuş
Obesity, 2001
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Ca2+ mobilization primes protein kinase C in human platelets. Ca2+ and phorbol esters stimulate platelet aggregation and secretion synergistically through protein kinase C
W. Siess
The Biochemical journal, 1988
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Phosphorylation of the 47 KDa protein in gamma-thrombin-stimulated human platelets does not activate phospholipase A2: Evidence against lipocortin
Eduardo Lapetina
Biochemical and Biophysical Research Communications, 1986
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Platelet Aggregation Unchanged by Lipoprotein-Associated Phospholipase A2 Inhibition: Results from an In Vitro Study and Two Randomized Phase I Trials
Colin Macphee
PLoS ONE, 2014
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Restoration of Responsiveness of Phospholipase Cγ2-Deficient Platelets by Enforced Expression of Phospholipase Cγ1
Peter Newman
PLOS ONE, 2015
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Human group II 14 kDa phospholipase A2 activates human platelets
Kenneth Clemetson
Biochemical Journal, 1997
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Aggregation-dependent, integrin-mediated increases in cytoskeletally associated PtdInsP2 (4,5) levels in human platelets are controlled by translocation of PtdIns 4-P 5-kinase C to the cytoskeleton
nullin divecha
The EMBO Journal, 1996
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Inhibition of Calpain Blocks Platelet Secretion, Aggregation, and Spreading
Ira M Herman
Journal of Biological Chemistry, 1999
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Activation of Human Platelets by Misfolded Proteins
Theo Van Berkel
Arteriosclerosis, Thrombosis, and Vascular Biology, 2007
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Mechanism of Activation and Functional Role of Protein Kinase Cη in Human Platelets
Yamini Bynagari
Journal of Biological Chemistry, 2009
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Co-activation of Gi and Gq proteins exerts synergistic effect on human platelet aggregation through activation of phospholipase C and Ca2+ signalling pathways
Husain Arif
1999
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Biphasic Activation of PKBα/Akt In Platelets
H. Banfic
Journal of Biological Chemistry, 1998
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A role for phosphatidylinositol 3-kinase in platelet aggregation in response to low, but not high, concentrations of PAF or thrombin
Mohamed Sayed
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1999
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Phospholipase A2 and phospholipase C activities of platelets. Differential substrate specificity, Ca2+ requirement, pH dependence, and cellular localization
Md Motasim Billah
Journal of Biological Chemistry, 1980
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Platelets: Physiology and Biochemistry
Beate Kehrel
Seminars in Thrombosis and Hemostasis, 2005
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PKCα regulates platelet granule secretion and thrombus formation in mice
Matthew Harper
The Journal of clinical …, 2009
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Plasma Phospholipid Transfer Protein Promotes Platelet Aggregation
Anna Babinska
Thrombosis and Haemostasis, 2018
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The association of pp125FAK, pp60Src, CDC42Hs and Rap1B with the cytoskeleton of aggregated platelets is a reversible process regulated by calcium
Debabrata Dash
FEBS Letters, 1995
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A Critical Role for Phospholipase C 2 in IIb 3-mediated Platelet Spreading
David Vaux
Journal of Biological Chemistry, 2003
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Intracellular Ca2+ rise in human platelets induced by polymorphonuclear-leucocyte-derived cathepsin G
Chiara cerletti
Biochemical Journal, 1992
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Activation of Protein Kinase C Is Required for the Stable Attachment of Adherent Platelets to Collagen but Is Not Needed for the Initial Rapid Adhesion Under Flow Conditions
Renata Polanowska-Grabowska
Arteriosclerosis, Thrombosis, and Vascular Biology, 1999
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Thrombin activation of human platelets dissociates a complex containing gelsolin and actin from phosphatidylinositide-specific phospholipase Cγ1
Joseph Baldassare
Biochemical Journal, 1997
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Response:Role of PKC in collagen-related peptide-induced platelet activation
Jianguo Jin
Blood, 2009
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A novel role for phospholipase D as an endogenous negative regulator of platelet sensitivity
Tomas Lindahl
Cellular Signalling, 2012
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Hypersensitivity of phospholipase C in platelets of spontaneously hypertensive rats
Adnane Remmal
Hypertension, 1987
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Interrelations of Platelet Aggregation and Secretion
Richard Feinman
Journal of Clinical Investigation, 1977
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Dual Role of Platelet Protein Kinase C in Thrombus Formation: STIMULATION OF PRO-AGGREGATORY AND SUPPRESSION OF PROCOAGULANT ACTIVITY IN PLATELETS
I. Munnix
Journal of Biological Chemistry, 2006
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