The Tumor Suppressor Smad4 Is Required for Transforming Growth Factor β–Induced Epithelial to Mesenchymal Transition and Bone Metastasis of Breast Cancer Cells
Clemens Lowik
Cancer Research, 2006
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The Tumor Suppressor Smad4 Is Required for Transforming Growth Factor B-Induced Epithelial to Mesenchymal Transition and Bone Metastasis of Breast Cancer Cells
Jeroen Buijs
2006
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Smad3 is a key nonredundant mediator of transforming growth factor beta signaling in Nme mouse mammary epithelial cells
Silvia Cazzola
Molecular Cancer Research, 2009
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Specific interactions between Smad proteins and AP-1 components determine TGFβ-induced breast cancer cell invasion
Carl-henrik Heldin
Oncogene, 2013
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Transforming Growth Factor-β1, Transforming Growth Factor-β2, and Transforming Growth Factor-β3 Enhance Ovarian Cancer Metastatic Potential by Inducing a Smad3-Dependent Epithelial-to-Mesenchymal Transition
Thúy Vy
Molecular Cancer Research, 2008
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Smad4-expression is decreased in breast cancer tissues: a retrospective study
Jürgen Dippon
BMC cancer, 2006
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Smad4-Independent TGF-β Signaling in Tumor Cell Migration
Andre Menke
Cells Tissues Organs, 2007
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TGF- and the Smad Signaling Pathway Support Transcriptomic Reprogramming during Epithelial-Mesenchymal Cell Transition
Carl-henrik Heldin
Molecular Biology of The Cell, 2005
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Definition of smad3 phosphorylation events that affect malignant and metastatic behaviors in breast cancer cells
eunjin BAE
Cancer research, 2014
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Attenuation of Smad2 activity shows resistance to TGF-β signalling in mammary adenocarcinoma (MCF-7) cells
Suman Sengupta
Cell Biology International, 2013
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Transforming growth factor-β1 suppresses bone morphogenetic protein-2-induced mesenchymal-epithelial transition in HSC-4 human oral squamous cell carcinoma cells via Smad1/5/9 pathway suppression
Masaharu Kamo
Oncology Reports, 2016
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Effect of Smad7 Expression on Metastasis of Mouse Mammary Carcinoma JygMC(A) Cells
Teruo Inamoto
JNCI: Journal of the National Cancer Institute, 2005
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A SNAIL1–SMAD3/4 transcriptional repressor complex promotes TGF-β mediated epithelial–mesenchymal transition
Federico Rojo
Nature Cell Biology, 2009
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Evidence That Smad2 Is a Tumor Suppressor Implicated in the Control of Cellular Invasion
M. Mareel
Journal of Biological Chemistry, 1999
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Breast cancer bone metastasis mediated by the Smad tumor suppressor pathway
Inna Serganova
Proceedings of the National Academy of Sciences, 2005
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Transforming growth factor-β1 suppresses bone morphogenetic protein-2/Smad signaling in human oral squamous cell carcinoma cell HSC-4 by downregulation of Smad1/9 expression
Masaharu Kamo
The Molecular Biology Society of Japan, 2016
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Critical Role of Smad2 in Tumor Suppression and Transforming Growth Factor-β–Induced Apoptosis of Prostate Epithelial Cells
David Danielpour
Cancer Research, 2009
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LMO4 can interact with Smad proteins and modulate transforming growth factor-β signaling in epithelial cells
Xiaoli Xu
Oncogene, 2006
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SMAD4 loss enables EGF, TGFβ1 and S100A8/A9 induced activation of critical pathways to invasion in human pancreatic adenocarcinoma cells
Paddy Tighe
Oncotarget, 2016
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Smad3 in the mammary epithelium has a nonredundant role in the induction of apoptosis, but not in the regulation of proliferation or differentiation by transforming growth factor-β
Gertraud Robinson
Cell Growth and Differentiation, 2002
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Cancer-associated fibroblasts induce epithelial-mesenchymal transition of breast cancer cells through paracrine TGF-β signalling
Stephane Bolduc
British journal of cancer, 2014
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Sustained TGFβ exposure suppresses Smad and non-Smad signalling in mammary epithelial cells, leading to EMT and inhibition of growth arrest and apoptosis
Stefan Imreh
Oncogene, 2007
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Differential effect of the expression of TGF-β pathway inhibitors, Smad-7 and Ski, on invasive breast carcinomas: relation to biologic behavior
Christina Magkou
Apmis, 2011
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The Dual Role of Smad7 in the Control of Cancer Growth and Metastasis
Veronica De Simone
International Journal of Molecular Sciences, 2013
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Differential regulation of TGF-β signaling through Smad2, Smad3 and Smad4
Anke Klippel
Oncogene, 2003
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Transforming growth factor β signaling regulates the invasiveness of normal mammary epithelial cells and the metastasis formation of tumor cells
Vida Vafaizadeh
Hormone Molecular Biology and Clinical Investigation, 2012
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Differential regulation of TGF-beta signaling through Smad2, Smad3 and Smad4
Anke Klippel
Oncogene, 2003
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Smad Signaling Is Required to Maintain Epigenetic Silencing during Breast Cancer Progression
Hamid Abdolmaleky, Panagiotis Papageorgis
Cancer Research, 2010
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TGF-β signaling, Smads, and tumor suppressors
Richard W Padgett
BioEssays, 1998
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Reversible Smad-Dependent Signaling between Tumor Suppression and Oncogenesis
Miki Murata
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Activation of Canonical BMP4-SMAD7 Signaling Suppresses Breast Cancer Metastasis
Robin Anderson
Cancer Research, 2020
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Breast cancer anti-estrogen resistance 3 inhibits transforming growth factor β/Smad signaling and associates with favorable breast cancer disease outcomes
Jimin Guo, Charles Rajadurai
Breast Cancer Research, 2014
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