Activation of the COOH-terminal Src kinase (Csk) by cAMP-dependent Protein Kinase Inhibits Signaling through the T Cell Receptor (original) (raw)

Combined Spatial and Enzymatic Regulation of Csk by cAMP and Protein Kinase A Inhibits T Cell Receptor Signaling

Kjetil Taskén

Journal of Biological Chemistry, 2003

View PDFchevron_right

Interrogating cAMP-dependent Kinase Signaling in Jurkat T Cells via a Protein Kinase A Targeted Immune-precipitation Phosphoproteomics Approach

Matthew Stokes

Molecular & Cellular Proteomics, 2013

View PDFchevron_right

Cyclic AMP-mediated immune regulation — Overview of mechanisms of action in T cells

Kjetil Taskén

Cellular Signalling, 2011

View PDFchevron_right

Inhibition of T lymphocyte activation by cAMP is associated with down-regulation of two parallel mitogen-activated protein kinase pathways, the extracellular signal-related kinase and c-Jun N-terminal kinase

yossi granot

Journal of Immunology, 1996

View PDFchevron_right

Removal of C-Terminal Src Kinase from the Immune Synapse by a New Binding Protein

Michel Moutschen

Molecular and Cellular Biology, 2005

View PDFchevron_right

Regulation of src family tyrosine kinases in lymphocytes

Tomas Mustelin

Trends in Biochemical Sciences, 1993

View PDFchevron_right

Inhibition of Antigen-Specific T Cell Proliferation and Cytokine Production by Protein Kinase A Type I

Kjetil Taskén

The Journal of Immunology, 2002

View PDFchevron_right

Knockdown of C-terminal Src kinase by siRNA-mediated RNA interference augments T cell receptor signaling in mature T cells

Mohammed Amarzguioui

European Journal of Immunology, 2004

View PDFchevron_right

cAMP: a multifaceted modulator of immune synapse assembly and T cell activation

Cosima Baldari

Journal of leukocyte biology, 2017

View PDFchevron_right

Tyrosine 192 within the SH2 domain of the Src-protein tyrosine kinase p56Lck regulates T-cell activation independently of Lck/CD45 interactions

Susana Minguet

Cell Communication and Signaling

View PDFchevron_right

Effects of Type I Protein Kinase A Modulation on the T Cell Distal Pole Complex

Kjetil Taskén

Scandinavian Journal of Immunology, 2011

View PDFchevron_right

Function of the Src-family kinases, Lck and Fyn, in T-cell development and activation

Arthur Weiss

Oncogene, 2004

View PDFchevron_right

Suppression of T-cell responsiveness by inducible cAMP early repressor (ICER)

Josef Bodor

Journal of leukocyte biology, 2001

View PDFchevron_right

Regulation of Src Family Kinases Involved in T Cell Receptor Signaling by Protein-tyrosine Phosphatase CD148

Arthur Weiss

Journal of Biological Chemistry, 2011

View PDFchevron_right

c Cytokine Receptor-Induced Stimulation of cAMP Response Element Binding Protein Phosphorylation Requires Protein Kinase C In Myeloid Cells: A Novel Cytokine Signal Transduction Cascade

Yufang Shi

The Journal of Immunology, 2001

View PDFchevron_right

Molecular mechanism of T-cell activation: role of protein tyrosine kinases in antigen receptor-mediated signal transduction

Margot Thome

Research in immunology

View PDFchevron_right

p56lck-independent activation and tyrosine phosphorylation of p72syk by T-cell antigen receptor/CD3 stimulation

T. Mustelin

Proceedings of the National Academy of Sciences, 1994

View PDFchevron_right

CD2 singnaling in T cells involves tyrosine phosphorylation and activation of the Tec family kinase, EMT/ITK/TSK

Arnold Han

International Immunology, 1996

View PDFchevron_right

The lymphocyte-specific protein tyrosine kinase p56lck is hyperphosphorylated on serine and tyrosine residues within minutes after activation via T cell receptor or CD2

Andrés Alcover, Remi Fagard

European Journal of Immunology, 1989

View PDFchevron_right

T Cell Activation Results in Conformational Changes in the Src Family Kinase Lck to Induce Its Activation

Roland Hartig

Science Signaling, 2013

View PDFchevron_right

Inhibition of cAMP degradation improves regulatory T cell-mediated suppression

Tobias Bopp

The Journal of …, 2009

View PDFchevron_right

The T-cell antigen receptor utilizes Lck, Raf-1, and MEK-1 for activating mitogen-activated protein kinase. Evidence for the existence of a second protein kinase C-dependent pathway in an Lck-negative Jurkat cell mutant

Arthur Weiss

Journal of Biological Chemistry, 1994

View PDFchevron_right

Release from Tonic Inhibition of T Cell Activation through Transient Displacement of C-terminal Src Kinase (Csk) from Lipid Rafts

Tomas Mustelin

Journal of Biological Chemistry, 2001

View PDFchevron_right

TCR/CD3-Induced Activation and Binding of Emt/Itk to Linker of Activated T Cell Complexes: Requirement for the Src Homology 2 Domain

T. Kawakami

The Journal of Immunology, 2000

View PDFchevron_right